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Full-Text Articles in Life Sciences

Young Germ Cell Depleted Ovaries In Post-Reproductive Mice And Its Effects On Immune Function, Mckenna Walters May 2019

Young Germ Cell Depleted Ovaries In Post-Reproductive Mice And Its Effects On Immune Function, Mckenna Walters

Undergraduate Honors Capstone Projects

It has previously been shown that young, cycling ovarian transplantation in aged female mice increased the general health and life span in regard to their post-reproductive health. It has further been hypothesized that this enhancement of health is directly influenced by the ovarian somatic cells. To address this hypothesis, transplants of young germ cell depleted and germ cell containing ovaries were performed on female mice. The purpose of this study is to continue to discern the reproductive influence on aging health, specifically in the area of immunological well-being. Control group mice were separated by age and treatment mice were subsequently …


A Review Of Osteoarthritis, Madelin Brooke Session May 2019

A Review Of Osteoarthritis, Madelin Brooke Session

Undergraduate Honors Capstone Projects

Osteoarthritis is a degenerative joint disease which plagues many older animals and humans. It is a disease that is characterized by the degeneration of joint cartilage, inflammation, as well as chronic pain and stiffness that results from this disorder. Unfortunately, most of the treatments for this painful and chronic disease mostly involve pain management and temporary relief strategies. These strategies usually include pain medication, non-steroidal anti-inflammatory drugs, injectable lubricants, as well as surgical techniques. However, because these treatments are just temporary fixes meant for pain management and to improve quality of life they must continue throughout the remainder of the …


Investigation Of The Toxic Affect Of Manganese On Ruminal Microbial Digestion And Growth, Erin Dearing May 2005

Investigation Of The Toxic Affect Of Manganese On Ruminal Microbial Digestion And Growth, Erin Dearing

Undergraduate Honors Capstone Projects

This research investigated the toxic effect of manganese, in a reduced chemical state, on rumen microbial metabolism and growth. The reduced form of manganese is the soluble state found in subsurface waters and has a high red-ox potential. In the study, we investigated the effects of reduced manganese at varying concentrations, on rumen microbial ability to replicate and metabolize carbohydrates. The hypotheses that we tested were as follows: (1) reduced manganese decreases the rate of pH drop associated with rumen culture fermentation of a com based diet and (2) reduced manganese decreases the bacterial growth in rumen culture, as measured …