Life Sciences Commons^™

An Evolutionary Pathway For Coping With Emerging Infectious Disease, Scott Lyell Gardner, Daniel R. Brooks, Walter A. Boeger, Eric P. Hoberg

Zea E-Books Collection

Emerging infectious disease (EID) represents an existential threat to humanity. EIDs are increasing in frequency and impact because of climate change and other human activities. We are losing the battle against EIDs because of improper assessment of the risk of EID. This stems from adherence to a failed paradigm of pathogen-host associations that suggests EIDs ought to be both unpredictable and rare. That, in turn, leads to policies suggesting that crisis response is the best we can do. Real-time and phylogenetic assessments show EIDs to be neither rare nor unpredictable—this is the parasite paradox that shows the failures of the …

Antimicrobial Resistance In Eskape Pathogens And Its Effect On Modern Medicine And Treatment, Cameran Runge

Honors Theses

Abstract

ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella

pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter

spp.) are seeing a growing resistance to multiple classes of antibiotics. Misuse and overuse of antibiotics have played directly into the resistance observed, and the problem is growing exponentially. Antibiotic resistance is partially due to several intrinsic factors limiting the drug's uptake. These include efflux pumps, increased biofilm production, and reduced cell wall permeability in the resistant bacteria. ESKAPE pathogens also acquire resistance through horizontal gene transfer and plasmids. As antibiotics have become less effective, the bacteria can continue to thrive, leading to a detrimental …

Exploring Modern Trends And Prevention Strategies For Childhood Obesity: A Comprehensive Literature Review, Anya E. Bogen

Honors Theses

This literature review seeks to provide an overview of the current research on childhood obesity. The study examines the prevalence and causes of childhood obesity, including genetic, environmental, and behavioral factors. The review also discusses the health consequences associated with childhood obesity, such as the increased risk for chronic diseases and psychological and social problems. Additionally, the review explores the effectiveness of interventions designed to prevent childhood obesity, including individual lifestyle modifications, education from health practitioners and school programs, and global, national, and state programs to promote wellness. The literature review concludes that childhood obesity is a complex and multifactorial …

Multilingual Zambia - Language Issues In Primary/Secondary Schools Of The Eastern/Southern Provinces, Kenzie Steiner

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Introduction: Zambia is a multilingual country that uses 8 different languages for instruction including English and 7 other indigenous languages.

Methods: Survey research conducted between May-June 2022 on 6-7th graders within 9 Zambian schools. Classroom observations made and teachers interviewed.

Results: In Eastern and Southern Provinces, Zambian teachers speak an average of 5 languages while students speak an average of 2. Both teachers and students say English remains the most important language followed by first languages.

Conclusion: Continued research on language-in-education policies and impacts on student performance must be conducted if “One Zambia, One Nation” is meant to promote all …

Syndemics And Social Factors: Infectious Disease Patterns Within The Population Of People Experiencing Homelessness In The United States, Kathleen Berzonsky

Honors Theses

Individuals experiencing homelessness are at increased risk of suffering from infectious diseases. This is due to a number of social factors and healthcare disparities, as well as the idea of syndemics, by which diseases cluster together to worsen disease burden. Current intervention strategies approach treatment from a post-infection perspective, but reducing transmission rates of infectious diseases within the population of people experiencing homelessness will require a shift in the healthcare framework. The issue of people experiencing homelessness must be viewed through a biosocial lens, focusing on preventative care and treatment. I provide an overview of the social factors governing infectious …

Maize, Fish, And Leafy Greens: Agricultural Diversity In Rural Zambia, Claire Gillespie

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

In Zambia, where 40% of children are stunted, there is limited interest in farming among primary school children as they consider their future. As grocery stores replace open-air markets, access to indigenous foods will become more difficult. Although 73 different types of foods were found in open-air markets, Zambian diets tend to be monotonous. Maize is the staple food and maize-based foods such as nshima are consumed daily, perpetuating low nutritional intake. Increasing crop diversity can increase balanced diets in Zambian school children and better support a growing population.

Running From Malnutrition: Zambian Children And Growth In The Eastern And Southern Provinces, Cole Murphy

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Although malnutrition rates remain high in Zambia, there are limited data for primary school children on factors that contribute to poor growth. This study was designed to examine one factor rarely considered in research about stunting, i.e., energy expenditure among primary school children and its contribution to short stature. § §Historically, stunting has been a major public health issue in much of sub-Saharan Africa and continues to yield severe consequences for physical and mental development throughout the lifespan (Iversen et al., 2022). §Both household food insecurity and dietary diversity are significantly associated with stunting in Sub-Saharan Africa (Gassara et al., …

Bugged By Bugs: A Comprehensive Guide To Pest Control, Brandon Runyon

Department of Entomology: Distance Master of Science Projects

This book aims to create a user-friendly guide tocommercial pest control practices covering German cockroaches, bed bugs, odorous house ants, pavement ants, brown recluse spiders, wolf spiders, house flies, and fruit flies. We will address these pests in the following locations: hotels, restaurants, apartments, and offices.

Diagnosing Neurocysticercosis In Skeletonized Human Remains Of Forensic Importance, John O. Obafunwa, Karl Reinhard

Karl Reinhard Publications

Neurocysticercosis is endemic in many parts of the underdeveloped and developing countries, with continuous presence in developed countries due to the influx of migrants from regions where the diseases are endemic. Neuroimaging, anatomic pathological techniques, immunodiagnostic tests, clinical examination and epidemiologic considerations will easily provide the diagnosis. However, physicians in developed countries are perhaps progressively missing the diagnosis, and need to re-acquaint themselves with the condition and acquire a high suspicion index. The authors present a medicolegal case where the forensic team made a conclusion of neurocysticercosis (among other diagnoses), following post mortem examination of a largely skeletonized and mummified …

The 3p Framework: A Comprehensive Approach To Coping With The Emerging Infectious Disease Crisis, Orsolya Molnár, Eric Hoberg, Valeria Trivellone, Gábor Földvári, Daniel R. Brooks

MANTER: Journal of Parasite Biodiversity

The COVID-19 pandemic is the latest example of the profound socioeconomic impact of the emerging infectious disease (EID) crisis. Current health security measures are based on a failed evolutionary paradigm that presumes EID is rare and cannot be predicted because emergence requires the prior evolution of novel genetic capacities for colonizing a new host. Consequently, crisis response through preparation for previously emerged diseases and palliation following outbreaks have been the only health security options, which have become unsustainably expensive and unsuccessful. The Stockholm paradigm (SP) is an alternative evolutionary framework that suggests host changes are the result of changing conditions …

Stepping-Stones And Mediators Of Pandemic Expansion: A Context For Humans As Ecological Super-Spreaders, Eric P. Hoberg, Walter A. Boeger, Daniel R. Brooks, Valeria Trivellone, Salvatore J. Agosta

MANTER: Journal of Parasite Biodiversity

Humans represent ecological super-spreaders in the dissemination and introduction of pathogens. These processes, consistent with the dynamics of the Stockholm paradigm, are exemplified in the origin and globalized distributions of SARS-CoV-2 since initial recognition in central Asia during 2019 and 2020. SARS-like viruses are not widespread in mammals but appear widespread in chiropterans. Bats are isolated ecologically from most other assemblages of mammals in terrestrial systems. Humans may be the stepping-stone hosts for broad global dissemination and wider infection (given the opportunity) among diverse assemblages of mammals in which host and viral capacity are compatible. Human globalization mediated insertion in …

Don’T Forget To Wash! Water, Sanitation, And Hygiene Among Zambian Students, Katie Schmitz

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Introduction: Water, sanitation, and hygiene practices in sub-Saharan Africa, including Zambia, have not met the Millennium Development Goals (MDGs) and remain inadequate to improve the overall health and wellbeing of most populations.

Methods: Survey research, interviews, WASH observations, and anthropometric assessment were conducted between May-June 2022 on 6-7th grade students within 6 Zambian schools.

Results: While hygiene knowledge was prominent, and handwashing stations and pit latrines were available, schools rarely supplied soap or toilet paper. Diarrheal and respiratory diseases were common and water shortages remain problematic with some students traveling long distances to reach a water source.

Discussion: As in …

Dental Decay In Zambian School Children In Eastern And Southern Provinces, Elizabeth Graham

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Introduction: Dental caries is the most prevalent and infectious disease worldwide. Zambia has a high rate of vitamin A deficiency, and this deficiency is associated with dental caries.

Methods: Visual dental checks, interviewing, and anthropometric assessments were done on 781 Zambian primary school children.

Results: Caries rates are 20% among sample populations, males have more decay than females, first molars are the most decayed, a majority use toothbrushes to clean their teeth, and children who eat vitamin A rich foods are less likely to have dental caries.

Discussion: Caries’ rates in the Southern and Eastern provinces are higher than in …

Regenerating Agroecosystems By Overcoming Human Exceptionalism In Designing For Increased Equity Of Benefits From Ecoservices, Ali Loker, Charles A. Francis

Department of Agronomy and Horticulture: Faculty Publications

Our commentary explores three critical issues related to ecosystem services. First is how ecoservices are currently designed and implemented primarily for human benefit without concern for how these impact other species. We conclude that awareness of this imbalance is the first step toward meaningful change. Second we observe that human exceptionalism guides most decisions, and ask whether we can overcome this mind-set to embrace ecoregeneration and design of resilient and mutually beneficial agroecosystems. Our attitude toward the challenge and moving toward greater humility about human roles that guide management decisions in the ecosystem is a requisite for change. Third we …

Circling The Drain: The Extinction Crisis And The Future Of Humanity, Rodolfo Dirzo, Gerardo Ceballos, Paul R. Ehrlich

Harold W. Manter Laboratory: Library Materials

Humanity has triggered the sixth mass extinction episode since the beginning of the Phanerozoic. The complexity of this extinction crisis is centered on the intersection of two complex adaptive systems: human culture and ecosystem functioning, although the significance of this intersection is not properly appreciated. Human beings are part of biodiversity and elements in a global ecosystem. Civilization, and perhaps even the fate of our species, is utterly dependent on that ecosystem’s proper functioning, which society is increasingly degrading. The crisis seems rooted in three factors. First, relatively few people globally are aware of its existence. Second, most people who …

Examining Correlates Of Feeding Practices Among Parents Of Preschoolers, Deepa Srivastava, Lucy R. Zheng, Dipti Dev

Department of Child, Youth, and Family Studies: Faculty Publications

Background: Parent feeding practices play a critical role in children’s eating behaviors. Limited research has explored child-level correlates of parent feeding practices.

Aim: To identify correlates of feeding practices (responsive and controlling) among parents of preschoolers US.

Methods: Participants included parents (n = 273) of preschoolers (3–5 years), recruited from Early Care and Education settings (n = 24) located in a metropolitan city in the US. Analysis included descriptives, correlations, and multiple regression.

Results: For responsive feeding practices, positive associations included child’s weight with unintentional modeling (β = .17, 95% CI [0.12, 0.53]), child vegetable consumption with behavioral role modeling …

Global Analysis Of High Cited Papers On “Impact Of Covid-19 On Mental Health” During 2020-21, Ghouse Modin Nabeesab Mamdapur Mr., Brij Mohan Gupta Dr., Sandeep Grover Dr.

Library Philosophy and Practice (e-journal)

A bibliometric analysis based on 160 highly cited papers extracted from the Scopus international database was carried out to provide insights into literature characteristics and publication performances of various participating actors on “Impact of COVID-19 on Mental Health”. Quantitative and qualitative Indicators were applied to measure the productivity and citation impact of most productive participating countries, organizations, authors, journals and significant keywords and to visualise and measure collaborative interaction among them using VOSviewer software. Results obtained from this study can provide valuable information for researchers and policy-makers to identify present and future hotspots in research on “Impact of COVID-19 on …

Rejection Of African Indigenous Food: The Case Of Rwanda, Eugene Baraka

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Rwanda has one of the highest stunting rates among children globally, and malnutrition remains one of the most pressing public health issues. Lack of diversified diets, due to colonialization and nutrition transition, is the leading cause of the double burden of malnutrition in the country where the progress to reduce undernutrition is slow and obesity rates are rapidly rising. Consumption of indigenous foods has proven to diversify diets, but very few studies have been conducted to assess which ones are available for consumption in Rwanda. The purpose of this study was to assess the availability and use of indigenous foods …

Food Sourcing And The Relationship To Height Of 6th To 7th Graders In Southern Ethiopia And Zambia, Flora Bescansa Luers

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Introduction: Zambia and Ethiopia are Sub-Saharan African countries experiencing high rates of malnutrition and stunting. This study examines food sourcing and its relationship to stunting.

Methods: Anthropometric assessment and food frequency-sourcing interviews were taken for 488 6th-7th graders in Livingstone, Zambia and Hawassa, Ethiopia. Data were analyzed using ANOVA.

Results: Most students sourced food from local markets and home gardens; however Zambian students used a greater variety of sources. Those sourcing from home gardens were significantly taller.

Discussion: Home gardening provides economic and health benefits, as well as food security. A focus on preservation and use …

Bedbug Education, Treatment, And Prevention, Elizabeth Bedford

Department of Entomology: Distance Master of Science Projects

Cimex lectularius (bedbug) has become a severe issue in more recent years due to travel, immigration, and importation of products. Unfortunately, most people do not know their biology hence do not treat these arthropods correctly. Many myths and misinformation are currently available to people on the internet and with pest professionals. Education and proper treatment must eradicate these pests in homes, commercial buildings, and other places. To prove whether or not education with treatment garners better results,ten homes were treated with the same heating and chemical process, with only five being educated before, during and after. All homes were inspected …

Molecular Identification Of Parasites In An Intestinal Coprolite From A Mummified Religious Dignitary Of The Piraino Mother Church Crypt, Sicily, Amanda Rollins, Krystiana Krupa, Georgia Millward, Dario Piombino-Mascali, Karl Reinhard, Frederika Kaestle

Karl Reinhard Publications

Intestinal contents were sampled from a spontaneously enhanced mummy from the Sepulcher of the Priests of the Piraino Mother Church in the Province of Messina, Sicily. This adult male mummy, Piraino 1, is an unidentified religious dignitary dating from the late-18th to mid-19th centuries. Immunological and molecular diagnostics were used to test for common and clinically significant parasites. A morphological diagnosis of Trichuris trichiura (whipworm) was confirmed genetically. A previously undetected Enterobius vermicularis (pinworm) infection was also identified genetically. These data indicate that the Piraino 1 individual was simultaneously infected with multiple intestinal parasite species indicative of poor hygiene. This …

Nutritional Aspects Related To Covid-19: A Bibliometric Analysis Using Scopus Database, Arti Muley Dr, Srujana Medithi Dr

Library Philosophy and Practice (e-journal)

Nutrition therapy has lately gained attention as an effective way of combating the novel Coronavirus 2019 (COVID-19), especially to address the immunity in an individual and their overall health. The present study is a bibliometric assessment of research conducted to understand the role of nutrition in treating COVID-19 which was carried out since the pandemic's sudden outburst during 2020 and 2021 and published in the Scopus database. A total of 93 publications were found, and the results were studied by evaluating these documents. The present analysis identifies the active countries where the research was conducted, various types of documents wherein …

Availability And Consumption Of Vitamin A Foods Among Southern Ethiopian And Zambian Primary Students, Trang Vuong

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Understand vitamin A food availability in open-air markets (OAM’s), and consumption of those foods by primary school children in southern Ethiopia/Zambia.

Methods: Conducted inventories of all consumable/potable items and interviewed 6-7th grade students about consumption of items with vitamin A.

Results: Students consumed most of the 14 vitamin A foods/items sold in OAM’s. Zambian students ate more liver, pumpkin, squash, watermelon, and wild fruits, while Ethiopian students almost never consumed squash, watermelon or wild fruits.

Conclusions: The availability of Vitamin A foods in Ethiopian and Zambian OAMs are varied; however, Zambian children reportedly eat more vitamin A foods. Nutrition …

Statement Of World Aquatic Scientific Societies On The Need To Take Urgent Action Against Human-Caused Climate Change, Based On Scientific Evidence [Dear Colleague Letter], Scott A. Bonar, Brian R. Murphy, Leanne H. Roulson, Jesse T. Trushenski, Douglas J. Austen, Michael Edward Douglas

United States Fish and Wildlife: Staff Publications

Dear Colleague Letter from the American Fisheries Society to fellow scientific societies, July 25, 2020, about the urgent need for responsive collective action to mitigate impending radical climate change. Includes the Statement of World Aquatic Scientific Societies on the Need to Take Urgent Action Against Human-Caused Climate Change, Based on Scientific Evidence, emphasizing the importance of aquatic ecosystems. Includes extensive citations and notes.

"Water is the most important natural resource on Earth as it is vital for life. Aquatic ecosystems, freshwater or marine, provide multiple benefits to human society, such as provisioning of oxygen, food, drinking water, genetic resources; regulation …

Grains, Grasses, And Tubers: Staple Carbohydrates In The Diets Of Middle School Children Of Southern Zambia And Ethiopia, Brianna Juma

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Survey staple carbohydrate availability in local markets, complete anthropometric assessment, and interview primary school children about carbohydrate consumption in Southern Zambia and Ethiopia

Methods: Market inventories, anthropometric assessments, and interviews of 6th and 7th grade students

Results: Ethiopians have a greater diversity of available carbohydrates, have better overall anthropometric values compared to Zambian children, and consume more nutritious and varied carbohydrate types.

Conclusions: Diversity in carbohydrate availability and consumption, as well as more nutritious options, are associated with healthier growth rates among primary school children in Southern regions of Zambia and Ethiopia.

Protein Availability And Consumption, And Stunting Rates, For Primary School Children In The Southern Regions Of Ethiopia And Zambia, Megan Wackel

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

•Stunting is common in Sub-Sahara Africa, with millions of children who are short in stature also experiencing poor overall health and development, as well as poor school performance (Semba 2016; Semba, et al., 2016). •As many as 39% of children under 5 years of age in Ethiopia’s Sidama Region (formerly SNNPR) can be classified as stunted (CSA & ICF 2016). By comparison, 29% of under 5’s in Zambia’s Southern Province have short height for age (CSA, MOH, & ICF 2018). •Low protein and essential amino acid intake, among populations of 116 countries, has been suggested as the primary cause of …

Stunting And Infectious Disease In Ethiopian And Zambian Children, Alyssa Arndt

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

PURPOSE: To evaluate whether children who are malnourished/stunted are more likely to have experienced infectious disease.

METHODS: 6th and 7th students (n=546) were interviewed about health history and assessed using anthropometry.

RESULTS: Children who are short for their age also have higher rates of stunting. Malaria is the most experienced infectious disease.

CONCLUSIONS: Given that malaria was the most common infectious disease experience listed among middle school children, and that those who have experienced disease are more likely to be stunted, increased malaria prevention methods may improve the long-term health of Ethiopian and Zambian schoolchildren.

On The Inadequacy Of Species Distribution Models For Modelling The Spread Of Sars-Cov-2: Response To Araújo And Naimi, Joseph D. Chipperfield, Blas M. Benito, Robert B. O'Hara, Richard J. Telford, Colin J. Carlson

Public Health Resources

The ongoing pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing significant damage to public health and economic livelihoods, and is putting significant strains on healthcare services globally. This unfolding emergency has prompted the preparation and dissemination of the article “Spread of SARS-CoV-2 Coronavirus likely to be constrained by climate” by Araújo and Naimi (2020). The authors present the results of an ensemble forecast made from a suite of species distribution models (SDMs), where they attempt to predict the suitability of the climate for the spread of SARS-CoV-2 over the coming months. They argue that climate is …

Surveillance Of Culex And Aedes Mosquitoes In Lincoln, Lancaster County, Nebraska, William Noundou

Department of Entomology: Dissertations, Theses, and Student Research

In 2018, West Nile virus (WNV) was identified as the leading cause of mosquito-borne disease in the continental United States. In response to this very serious problem, the Lincoln-Lancaster County Public Health Department (LLCHD) reinforced their mosquito surveillance program, which constitutes one of the best available tools to fight against this serious threat to human health. The objectives of this study were to 1) expand knowledge of the activity and relative abundance of mosquito communities in understudied areas and 2) evaluate differences in mosquito communities by urban and rural location, especially focusing on known vector species. A total of 6 …

Dental Health Factors Among Primary School Children In Southern Regions Of Ethiopia And Zambia, Gisselle Hernandez

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Assess oral health status, and factors affecting oral health, among primary schoolchildren in southern Ethiopia and Zambia. Methods: Visual dental assessments, anthropometric measurements, and questionnaires used to collect data among 6th and 7th grade students. Results: Although stunting rates were nearly equal, decay rates were not; 17.51% of Zambian students and 47.27% of Ethiopian students had one or more decayed teeth. Ethiopian students with dental fluorosis (74.55%) had higher rates of decay than those without the condition (p < .05). There were also significant differences between Ethiopians and Zambians regarding use of dental hygiene tools: Ethiopians were more likely to use dental sticks, while Zambians employed toothbrushes for cleaning. Conclusions: Dental health and hygiene education, focused on unique socioecological settings, could improve the oral health status of Ethiopian and Zambian children.

PowerPoint file attached below