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Full-Text Articles in Life Sciences

A Polyglot Approach To Bioinformatics Data Integration: A Phylogenetic Analysis Of Hiv-1, Steven Reisman, Thomas Hatzopoulous, Konstantin Läufer, George K. Thiruvathukal, Catherine Putonti Jan 2017

A Polyglot Approach To Bioinformatics Data Integration: A Phylogenetic Analysis Of Hiv-1, Steven Reisman, Thomas Hatzopoulous, Konstantin Läufer, George K. Thiruvathukal, Catherine Putonti

George K. Thiruvathukal

As sequencing technologies continue to drop in price and increase in throughput, new challenges emerge for the management and accessibility of genomic sequence data. We have developed a pipeline for facilitating the storage, retrieval, and subsequent analysis of molecular data, integrating both sequence and metadata. Taking a polyglot approach involving multiple languages, libraries, and persistence mechanisms, sequence data can be aggregated from publicly available and local repositories. Data are exposed in the form of a RESTful web service, formatted for easy querying, and retrieved for downstream analyses. As a proof of concept, we have developed a resource for annotated HIV-1 …


The Finney County, Kansas Community Assessment Process: Fact Book, Debra J. Bolton Phd, Shannon L. Dick M.S. Jan 2017

The Finney County, Kansas Community Assessment Process: Fact Book, Debra J. Bolton Phd, Shannon L. Dick M.S.

Dr. Debra Bolton

This multi-lingual/multi-cultural study was called, Community Assets Processt, by the groups that “commissioned” it: Finnup Foundation, Finney County K-State Research & Extension, Western Kansas Community Foundation, Finney County United Way, Finney County Health Department, United Methodist Community Health Center (UMMAM), Center for Children and Families, Garden City Recreation Commission, and the Garden City Cultural Relations Board, because we intend for this to be an ongoing discussion. An objective, for those promoting the study, was to connect foundation, state, and federal funding with activities or services that addressed the true needs of people living in Finney County. The group was looking …


Statistical Contributions To Bioinformatics: Design, Modeling, Structure Learning, And Integration, Jeffrey S. Morris, Veera Baladandayuthapani Dec 2016

Statistical Contributions To Bioinformatics: Design, Modeling, Structure Learning, And Integration, Jeffrey S. Morris, Veera Baladandayuthapani

Jeffrey S. Morris

The advent of high-throughput multi-platform genomics technologies providing whole-genome molecular summaries of biological samples has revolutionalized biomedical research. These technologies yield highly structured big data, whose analysis poses significant quantitative challenges. The field of Bioinformatics has emerged to deal with these challenges, and is comprised of many quantitative and biological scientists working together to eectively process these data and extract the treasure trove of information they contain. Statisticians, with their deep understanding of variability and uncertainty quantification, play a key role in these efforts. In this article, we attempt to summarize some of the key contributions of statisticians to bioinformatics, …


Where's The Beef: Predicting The Effects Of Climate Change On Cattle Production In Western U.S. Rangelands, Sue Miller, Matthew Clark Reeves, Karen Bagne, John Tanaka Dec 2016

Where's The Beef: Predicting The Effects Of Climate Change On Cattle Production In Western U.S. Rangelands, Sue Miller, Matthew Clark Reeves, Karen Bagne, John Tanaka

Karen Bagne

No abstract provided.


Towards A Home-Based Virtual Reality Game System To Promote Exercise, Ashish Amresh, Rahul Salla Dec 2016

Towards A Home-Based Virtual Reality Game System To Promote Exercise, Ashish Amresh, Rahul Salla

Ashish Amresh

This paper presents the design and usability testing results for a home-based virtual reality game system that aims to promote exercise with the spin machine. The novelty of our approach lies in the design of the game mechanics that promote increased calorific output among the participants and the ease of setup with any commercially available Virtual Reality (VR) sensor. The paper describes the motivation behind the developed system, the design details of the games created to promote the use of the system and the results from a usability test conducted with 37 participants.