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Full-Text Articles in Life Sciences

Expressive Writing As A Coping Mechanism For Caregivers Of People With Parkinson's Disease, Sarah Beck Jun 2016

Expressive Writing As A Coping Mechanism For Caregivers Of People With Parkinson's Disease, Sarah Beck

Honors Theses

Caregivers face challenges that take a tremendous toll both mentally and physically, while also having to experience their changing relationship with a loved one who continuously deteriorates. (Ornstein, Gaugler, Devanand, Scarmeas, Zhu, & Stern, 2013). The purpose of my study will be to examine if utilizing expressive writing (EW) can benefit caregivers of loved ones with Parkinson’s disease. I hypothesized that EW would help alleviate caregiver burden, and decrease negative mood and healthier coping means, while caregivers who write within a positive framework will experience the greatest alleviation of burden, better reported mood, and coping means. In this study the …


Association Of Glucocorticoid Receptor Polymorphisms With Metabolic Characteristics And Bariatric Surgery In Bariatric Patients, Sebastien Gingras Jun 2016

Association Of Glucocorticoid Receptor Polymorphisms With Metabolic Characteristics And Bariatric Surgery In Bariatric Patients, Sebastien Gingras

Honors Theses

Cortisol acts on target tissues through the glucocorticoid receptor (GR). When in high concentration in the blood, it causes an obesity phenotype with hyperglycemia, hyperglyceridemia, hypertension and weight gain, known as Cushings’ Syndrome or Disease (CS/D). Hypersensitivity-causing single-nucleotide polymorphisms (SNPs) of the GR have been shown to lead to a similar phenotype. Because of the symptomatic resemblance between CS/D and Metabolic Syndrome (MS), we and others hypothesized that the MS may be a Cushingoid-like state with absence of hypercortisolemia, but with GR hypersensitivity. Additionally, the link between GR SNPs and the success of bariatric surgery as measured by the percent …


The Effects Of Early Confidence Interval Training On User Efficacy In A P300 Brain-Computer Interface Spelling Task, Adam Starkman Jun 2016

The Effects Of Early Confidence Interval Training On User Efficacy In A P300 Brain-Computer Interface Spelling Task, Adam Starkman

Honors Theses

Brain-computer interface (BCI) technology can provide communication for individuals suffering from degenerative neuromuscular disorders. The present study sought to demonstrate improved BCI performance in healthy individuals using confidence interval training with a P300 BCI spelling program. In this BCI interface, electroencephalographic (EEG) activity was recorded as participants attended to a specific target character within a matrix of flashing letters and numbers presented on a computer screen. The BCI uses the P300 Event Related Potential to select the intended character. In a prior patient case, use of a confidence measure that rejected questionable selections improved that user’s spelling efficiency. The present …


The Progression Of Neurological Impairment In Sport-Related Brain Injuries, Nicole Leo Jan 2016

The Progression Of Neurological Impairment In Sport-Related Brain Injuries, Nicole Leo

Honors Theses

Millions of Americans sustain traumatic head injuries each year when participating in various high and low-risk activities. Athletes, in general, are more prone to sustaining brain injuries than others, particularly those that participate in collision sports. This thesis discusses brain damage and long-term effects incurred by collision sport-related traumatic brain injuries such as the formation of amyloid-beta plaques in brain tissue and the increased possibility of developing neurodegenerative diseases such as Alzheimer's. In addition, brain development and plasticity over time are reviewed revealing the concept that brain plasticity and brain development are key processes that occur throughout childhood, adolescence, and …