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Full-Text Articles in Life Sciences
Code For "Noise-Enhanced Coding In Phasic Neuron Spike Trains", Cheng Ly, Brent D. Doiron
Code For "Noise-Enhanced Coding In Phasic Neuron Spike Trains", Cheng Ly, Brent D. Doiron
Statistical Sciences and Operations Research Data
This zip file contains Matlab scripts and ode (XPP) files to calculate the statistics of the models in "Noise-Enhanced Coding in Phasic Neuron Spike Trains". This article is published in PLoS ONE.
Acute Neuroinflammation Induces Ais Structural Plasticity In A Nox2-Dependent Manner, S. D. Benusa, N. M. George, B. A. Sword, G. H. Devries, J. L. Dupree
Acute Neuroinflammation Induces Ais Structural Plasticity In A Nox2-Dependent Manner, S. D. Benusa, N. M. George, B. A. Sword, G. H. Devries, J. L. Dupree
Anatomy and Neurobiology Publications
Background
Chronic microglia-mediated inflammation and oxidative stress are well-characterized underlying factors in neurodegenerative disease, whereby reactive inflammatory microglia enhance ROS production and impact neuronal integrity. Recently, it has been shown that during chronic inflammation, neuronal integrity is compromised through targeted disruption of the axon initial segment (AIS), the axonal domain critical for action potential initiation. AIS disruption was associated with contact by reactive inflammatory microglia which wrap around the AIS, increasing association with disease progression. While it is clear that chronic microglial inflammation and enhanced ROS production impact neuronal integrity, little is known about how acute microglial inflammation influences AIS …