Life Sciences Commons^™

The Involvement Of Urinary Kallikrein In The Renal Escape From The Sodium Retaining Effect Of Mineralocorticoids, M. Marin-Grez, N. B. Oza, Oscar A. Carretero

Henry Ford Hospital Medical Journal

It is well known that the normal kidney "escapes" the sodium retaining effect of mineralocorticoids. However, the mechanism that mediates this "escape" is not understood. The possible role of kallikrein in this "escape" phenomenon was investigated by placing seven dogs in metabolic cages and giving them a constant sodium diet. After they had been on this diet three days, urine was collected for two 24-hour periods. DOCA (25 mg/day) was then given intramuscularly for five days. Urine was collected daily during this DOCA period and for two additional 24- hour periods. Urine volume, sodium, potassium, protein, and kallikrein excretion were …

Experience With Cleft Lip And Palate At The Henry Ford Hospital, W. Peter Mccabe

Henry Ford Hospital Medical Journal

A detailed analysis is presented of 321 patients with clefts of the lip and/or palate treated at Henry Ford Hospital. Comments are made on past and future trends in the management of these complex entities.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

A Method Of Analyzing Mandibular Movement, Richard B. Mccoy

Loma Linda University Electronic Theses, Dissertations & Projects

Mandibular movement is considered to be a fundamental factor in the study, analysis, and treatment of occlusion. For many years, dentists have realized that dental health depends upon the compatibility of mandibular movements and occlusion. This realization has led to the development of new methods and techniques for recording accurately and scientifically the movements of the mandible. In order for this data to be of scientific value, it must be stored in a usable form which is easily available for analysis.

The purpose of this research project was to develop a procedure for storing and recalling mandibular-movement information. Before such …

Role Of Membrane-Associated Components Of Mycoplasma Arthritidis On The Biosynthesis Of Humoral Antibodies And Arthritogenic Properties In Experimental Animals, Lois M. Bergquist

Loma Linda University Electronic Theses, Dissertations & Projects

The virulence of animal-passaged Mycoplasma arthritidis (158) was demonstrated to be enhanced in rats by growth in oleic acid-enriched broth. The virulence of a laboratory-maintained culture of the same strain was unaffected by similar growth conditions. No differences either in the immune response as measured by complement-fixing (CF) antibodies or in the histogenesis of the disease were detected when rats were injected with animal-passaged M. arthritidis grown either in the presence or in the absence of oleic acid. All tests for metabolism-inhibiting (MI) antibodies in the rat were negative.

A Mycoplasma-associated immunosuppression of the primary and of the secondary hemagglutinin …

Author Index, 1953-1972

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Subject Index, 1953-1972

Henry Ford Hospital Medical Journal

No abstract provided.

The Effect Of Psyllium Hydrocolloid And Cholestyramine On Hepatic Bile Lipid Composition In Man, W. T. Beher, B. M. Schuman, M. A. Block, G. J. Lin, K. K. Casazza

Henry Ford Hospital Medical Journal

The effects of a mucoid - psyllium hydrocolloid - and an anion exchange polymercholestryamine - on the total cholesterol, total phospholipid, total bile salt, cholate, chenodeoxycholate, and deoxycholate concentrations of hepatic bile were determined in six post-cholecystectomy patients. Bile was obtained by drainage through an indwelling T-tube, which was clamped except during bile collection. Psyllium hydrocolloid treatment (12 gm/day) for 6 to 29 days had little or no effect on the cholesterol or phospholipid concentration of hepatic bile, but increased the total bile salt pool by gradually increasing the concentration of deoxycholate. Cholestyramine treatment (12 gm/day) for 8 to 12 …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Purpura Arthralgia Weakness Mixed Cryoglobulinemia Syndrome Treated With Splenectomy: A Case Report, Carl R. Haeger

Henry Ford Hospital Medical Journal

Weakness purpura mixed arthralgia cryoglobinemia (IgG - IgM) syndrome was first described by Meltzer in 1966. Such a case was recently reported after treatment with Cyclophosphamide and subsequent splenectomy for pancytopenia with beneficial effects on the cryocrit. The patient reported here underwent splenectomy without Cyclophosphamide and had subsequent amelioration of the clinical symptoms. Abnormal plasma cells found in the spleen presumably were responsible (at least in part) for the patient's symptomatology.

Malignant Histiocytosis Of The Robb-Smith Type (Histiocytic Medullary Reticulosis), Michael F. Macken, Ellis J. Van Slyck, Sheik M. Saeed

Henry Ford Hospital Medical Journal

A 60-year-old woman developed high fever, jaundice, anemia with pancytopenia and hepatosplenomegaly. She deteriorated rapidly and died one month later, having shown no beneficial effect from high dose corticosteroids and splenectomy. An antemortem diagnosis of malignant histiocytosis of the Robb-Smith type was made and duly confirmed by autopsy study. This rare disorder of the reticuloendothelial system, heretofore designated "histiocytic medullary reticulosis," deserves recognition and inclusion among the histiocytic diseases and in the classification of the lymphomas. Its proper nosologic designation is suggested.

A Microtechnique For The Isolation Of Cell Wall Deficient Organisms From Very Small Samples, Lloyd T. Dutcheshen, Philip C. Hessburg

Henry Ford Hospital Medical Journal

A miniaturized procedure using a modified microtiter plate is described for the isolation of cell wall deficient organisms. It is particularly useful when the volume of a liquid specimen is very small.

Concomitant Streptococcal Endocarditis And Tuberculous Pleuro-Pericardial Effusion, T. Madhavan, Evelyn J. Fisher, Frank Cox Jr., Edward L. Quinn

Henry Ford Hospital Medical Journal

No abstract provided.

Primary Peritonitis, M. Reza Jahadi, John G. Whitcomb

Henry Ford Hospital Medical Journal

No abstract provided.

Pasteurella Multocida Meningitis: Report Of A Case, Leo J. Bingley Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Kinesiology Of Knee Flexion Deformity Using Electromyography, Paul J. Roby

Loma Linda University Electronic Theses, Dissertations & Projects

A kinesiological electromyographic study was completed to determine the relative changes in muscle activity as a person walks and stands with different degrees of knee flexion deformity. The ultimate aim was to establish criteria for appropriate preventive and corrective measures relating to knee flexion deformity.

Six different muscles were implanted with wire electrodes. The subjects performed a series of walking and standing experiments with the knee flexed at selected angles by a locking leg brace to simulate knee flexion deformity. The electromyographic action potentials were monitored by analog tapes, oscilloscopes and closed circuit television. The analog tapes were displayed on …

Measurement Of Haversian Bone Remodelling By Means Of Tetracycline Labelling In Rib Of Rhesus Monkeys, Charles C. Schock, Frank R. Noyes, A. R. Villanueva

Henry Ford Hospital Medical Journal

Quantitative histologic measurements of haversian bone remodelling were made of mineralized rib cross sections in 13 healthy rhesus monkeys. With the aid of previous tetracycline labelling, coupled with the Villanueva Osteochrome stain, Frost's quantitative bone analysis revealed that: a) the mean haversian bone formation rate is 0.359 z 0.186 mm²/mm²/yr; b) the mean number of osteoid seams/mm² is 4.03 ± 1.64; c) the mean appositional rale is 1 33 ± 0 23 microns/day while the radial closure rate when all the labelled systems are corrected is 0.42 r 0.080 mm/year; d) the mean circumference of …

Nonparasitic Cysts Of The Liver: Analysis Of 36 Cases And Review Of Modern Diagnostic Techniques, Victor Lawoyin, Robert J. Priest

Henry Ford Hospital Medical Journal

A review is presented of 36 cases of nonparasitic cysts of the liver. These are uncommon and had been difficult to diagnose clinically. Diagnosis has usually been made by post-mortem examination and by surgery. Attention is focused on the merits of modern diagnostic methods to differentiate cystic from solid tumors of the liver. These methods include radioisotope scanning, ultrasonography, and abdominal arteriography.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Gout And Arterial Thrombosis, Frank J. Viozzi, Gilbert B. Bluhm, Jeanne M. Riddle

Henry Ford Hospital Medical Journal

Two hundred and eighty patients with primary gout diagnosed between the years 1959-64 at Henry Ford Hospital were studied to determine the frequency of myocardial infarction in the fourth, fifth and sixth decades. The retrospective data correlate with previously published reports of accelerated platelet turnover and our own observation of increased platelet surface activation in patients with gout. The results suggest an increased risk (or myocardial infarction before age 50 in patients with primary gout; this merits prospective study. The finding of increased platelet surface activation in patients with gout may provide an insight into the pathophysiology of the apparent …

Current Tests For Tubal Patency: Their Study And Comparison, Asghar Afsari, Robert J. Thompson

Henry Ford Hospital Medical Journal

Two hundred patients have been reviewed in whom culdoscopy or laparoscopy was performed for infertility study. During these two procedures, methylene blue was injected through an endocervical cannula for detection of tubal patency under direct visualization. When compared with 89 patients tested by utero-tubal insufflation and hystero-salpingography, results indicated that direct visualization of the tubes and dye hydrotubation appears to be the most reliable method. HSG proved to be the second most reliable method with a failure rate of 19.2%. The least accurate procedure in this study was UTI with CO₂ gas, where the failure rate was 24.7%. The …

Inhibition Of Kidney Mitochondrial Monoamine Oxidase Activity By The Nephrosis-Producing Aminonucleoside Of Puromycin, Paul Bartlett, Mei-Hwa Tu, Kathleen Ashworth

Henry Ford Hospital Medical Journal

Intraperitoneal administration in rats of a single large injection of the potent nephrotogenic aminonucleoside,6-dimethylamino-9-(3'-amino-3' =deoxy-β-D-ribofuranosyl)-purine, resulted in striking reductions in kidney cortex mitochondrial monoamine oxidase (MAO) activity, assayed on tyramine substrate The alterations in enzymatic activity correlated remarkably well with the onset and development of the massive proteinuria characteristic of the disease. The inhibitory effects were also produced in vitro, and Lineweaver-Burk reciprocal plots were clearly indicative of non-competitive inhibition. It is suggested that aminonucleoside inhibition of kidney mitochondrial MAO activity may be a biochemical lesion in the primary step of GBM collagen cross-link formation, whereby collagen fibrillogenesis is impaired …

Biopsy-Proven Amebic Colitis Treated With Metronidazole, Frederick R. Bode, Earl J. Van Volkinburg

Henry Ford Hospital Medical Journal

Amebiasis was diagnosed in a Vietnam veteran and treated in a conventional manner with diodoquin and tetracycline. Symptoms persisted over the next three and one-half years despite repeated courses of diodoquin. Amebic colitis was confirmed by biopsy through a sigmoidoscope. The patient then received a ten-day course of metronidazole (Flagyl). Studies are cited proving this single agent is the drug of choice in the oral therapy of all clinical forms of amebiasis.

In Memoriam: Thomas J. Heldt, M. D., 1883-1972, Eugene J. Alexander

Henry Ford Hospital Medical Journal

No abstract provided.

C-Reactive Protein: Potential Significance Of Quantitation In Patients With Chronic Diseases, Hajime Hayashi, Gerald A. Logrippo

Henry Ford Hospital Medical Journal

Serum C-reactive protein (CRP) levels in 351 patients with certain chronic diseases were assayed by a micro-double immunodiffusion technique developed and used in this hospital. Elevation of CRP values and severity of disease were evident in the following clinical entities: 31 of 54 patients (57%) with liver cirrhosis; 122 of 204 (60%) hepatitis patients; 34 of 52 (65%) patients with gastro-intestinal surgery; 8 of 21 (38%) uremic patients; and all of 20 patients with renal transplantation. There was good correlation between markedly elevated serum CRP values and degree of inflammation and/or physiologic stress during clinical course and recovery.

Genetic Counseling For Hemoglobinopathies: A Model For Large Scale Application, Charles E. Jackson, Esly S. Caldwell, Ellis J. Van Slyck

Henry Ford Hospital Medical Journal

This report describes a project in a large urban, predominantly black, high school which combined a hemoglobinopathy survey with an educational and genetic counseling emphasis. The faculty and students received information on sickle cell disease explaining its genetic and personal implications. About 29% of the 2,700 students received parental permission and volunteered for blood tests in the initial year. Blood was examined by starch gel electrophoresis during the first year and by cellulose acetate electrophoresis during the second year. Of the 1300 total individuals studied, 7% were found to have sickle cell trait and 2% hemoglobin C trait. The cellulose …

The Psychiatric Walk-In Clinic Service: An Interim Report Of Experience At Henry Ford Hospital, Boyd K. Bresnahan, Larry Schilhaneck

Henry Ford Hospital Medical Journal

No abstract provided.