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Full-Text Articles in Life Sciences

Insig2 Gene Polymorphism Is Associated With Increased Subcutaneous Fat In Women And Poor Response To Resistance Training In Men, Funda Orkunoglu-Suer, Heather Gordish-Dressman, Priscilla Clarkson, Paul Thompson, Theodore Angelopoulos, Paul Godron, Niall Moyna, Linda Pescatello, Paul Visich, Robert Zoeller, Brennan Harmon, Richard Seip, Eric Hoffman, Joseph Devaney Dec 2008

Insig2 Gene Polymorphism Is Associated With Increased Subcutaneous Fat In Women And Poor Response To Resistance Training In Men, Funda Orkunoglu-Suer, Heather Gordish-Dressman, Priscilla Clarkson, Paul Thompson, Theodore Angelopoulos, Paul Godron, Niall Moyna, Linda Pescatello, Paul Visich, Robert Zoeller, Brennan Harmon, Richard Seip, Eric Hoffman, Joseph Devaney

Priscilla M. Clarkson

Background A common SNP upstream of the INSIG2 gene, rs7566605 (g.-10,1025G>C, Chr2:118,552,255, NT_022135.15), was reported to be associated with obesity (Body Mass Index, [BMI]) in a genome-wide association scan using the Framingham Heart Study but has not been reproduced in other cohorts. As BMI is a relatively insensitive measure of adiposity that is subject to many confounding variables, we sought to determine the relationship between the INSIG2 SNP and subcutaneous fat volumes measured by MRI in a young adult population. Methods We genotyped the INSIG2 SNP rs7566605 in college-aged population enrolled in a controlled resistance-training program, (the Functional Polymorphism …


Objectively Measured Physical Activity In Urban Alternative High School Students, John R. Sirard, Martha Y. Kubik, Jayne A. Fulkerson, Chrisa Arcan Nov 2008

Objectively Measured Physical Activity In Urban Alternative High School Students, John R. Sirard, Martha Y. Kubik, Jayne A. Fulkerson, Chrisa Arcan

John Sirard

Introduction—Alternative high school students are an underserved population of youth at greater risk for poor health behaviors and outcomes. Little is known about their physical activity patterns. Purpose—The purpose of this study was to describe 1) physical activity levels of students attending alternative high schools (AHS) in St. Paul/Minneapolis, MN and 2) compliance with wearing a physical activity accelerometer. Methods—Sixty-five students (59% male, 65% <18 years>old, 51% African-American, 17% Caucasian, 32% mixed and other) wore an accelerometer during all waking hours for seven days as part of the baseline assessment for a school-based physical activity and dietary behavior intervention. Accelerometer data …


In Vivo Lumbo-Sacral Forces And Moments During Constant Speed Running At Different Stride Lengths, Joseph Seay, W. Scott Selbie, Joseph Hamill Nov 2008

In Vivo Lumbo-Sacral Forces And Moments During Constant Speed Running At Different Stride Lengths, Joseph Seay, W. Scott Selbie, Joseph Hamill

Joseph Hamill

The aim of this study was to introduce a Newton–Euler inverse dynamics model that included reaction force and moment estimation at the lumbo-sacral (L5-S1) and thoraco-lumbar (T12-L1) joints. Data were collected while participants ran over ground at 3.8 m s71 at three different stride lengths: preferred stride length, 20% greater than preferred, and 20% less than preferred. Inputs to the model were ground reaction forces, bilateral lower extremity and pelvis kinematics and inertial parameters, kinematics of the lumbar spine and thorax and inertial parameters of the lumbar segment. Repeated measures ANOVA were performed on the lower extremity sagittal kinematics and …


Aging Enhances Indirect Flight Muscle Fiber Performance Yet Decreases Flight Ability In Drosophila, Mark S. Miller, Panagiotis Lekkas, Joan M. Braddock, Gerrie P. Farman, Bryan A. Ballif, Thomas C. Irving, David W. Maughan, Jim O. Vigoreaux Aug 2008

Aging Enhances Indirect Flight Muscle Fiber Performance Yet Decreases Flight Ability In Drosophila, Mark S. Miller, Panagiotis Lekkas, Joan M. Braddock, Gerrie P. Farman, Bryan A. Ballif, Thomas C. Irving, David W. Maughan, Jim O. Vigoreaux

Mark S. Miller

We investigated the effects of aging on Drosophila melanogaster indirect flight muscle from the whole organism to the actomyosin cross-bridge. Median-aged (49-day-old) flies were flight impaired, had normal myofilament number and packing, barely longer sarcomeres, and slight mitochondrial deterioration compared with young (3-day-old) flies. Old (56-dayold) flies were unable to beat their wings, had deteriorated ultrastructure with severe mitochondrial damage, and their skinned fibers failed to activate with calcium. Small-amplitude sinusoidal length perturbation analysis showed median-aged indirect flight muscle fibers developed greater than twice the isometric force and power output of young fibers, yet cross-bridge kinetics were similar. Large increases …


Big Bobby Bonaduce: Still Searching For The Rink Of Dreams, Don Morrow May 2008

Big Bobby Bonaduce: Still Searching For The Rink Of Dreams, Don Morrow

Donald Morrow

No abstract provided.


Stomping The Shadow: The Elevation Of Snowboarding To The Olympic Pedestal From A Jungian Perspective, M. Popovic, Don Morrow Apr 2008

Stomping The Shadow: The Elevation Of Snowboarding To The Olympic Pedestal From A Jungian Perspective, M. Popovic, Don Morrow

Donald Morrow

No abstract provided.


International Journal Of Behavioral Nutrition And Physical Activity, John R. Sirard, Melissa C. Nelson, Mark A. Pereira, Leslie A. Lytle Apr 2008

International Journal Of Behavioral Nutrition And Physical Activity, John R. Sirard, Melissa C. Nelson, Mark A. Pereira, Leslie A. Lytle

John Sirard

Background: Little is known about how the home environmental supports physical activity and screen media usage. The purpose of this study was to develop and test the reliability and validity of a self-report instrument to comprehensively reflect the availability and accessibility of physical activity and screen media equipment in the home environment. Methods: Ten families participated in the initial field testing to provide feedback for instrument development. Thirty one adult participants, each of whom had at least one child 10–17 years old, completed two Physical Activity and Media Inventory (PAMI) instruments. The first PAMI was completed simultaneously, but independently, with …


Comparing The Effects Of Various Whole-Body Vibration Accelerations On Counter-Movement Jump Performance, David M. Bazett-Jones, Holmes W. Finch, Eric L. Dugan Feb 2008

Comparing The Effects Of Various Whole-Body Vibration Accelerations On Counter-Movement Jump Performance, David M. Bazett-Jones, Holmes W. Finch, Eric L. Dugan

Eric L. Dugan

While it seems that whole body vibration (WBV) might be an effective modality to enhance physical performance, the proper prescription of WBV for performance enhancement remains unknown. The purpose of this study was to compare the immediate effect of various WBV accelerations on counter movement jump (CMJ) height, the duration of any effect, and differences between men and women. Forty-four participants (33 men, 11 women) participated in no less than four CMJ familiarization sessions and completed all vibration sessions. Participants performed a pre-test (three maximal CMJs), followed randomly by one of five WBV accelerations; 1g (no-WBV control), 2.16g, 2.80g, 4.87g, …


Responses To Multi-Directional Surface Translations Involve Redistribution Of Proximal Versus Distal Strategies To Maintain Upright Posture, Stephanie L. Jones, Sharon M. Henry, Christine C. Raasch, Juvena R. Hitt, Janice Y. Bunn Feb 2008

Responses To Multi-Directional Surface Translations Involve Redistribution Of Proximal Versus Distal Strategies To Maintain Upright Posture, Stephanie L. Jones, Sharon M. Henry, Christine C. Raasch, Juvena R. Hitt, Janice Y. Bunn

Stephanie Jones

Evaluation of postural control in multiple planes is necessary to determine the movement strategies used to respond to unexpected perturbations. The present study quantified net joint torques of the lower limbs and trunk in the sagittal and frontal planes following multi-directional surface translations. Twenty-one healthy subjects stood with feet on separate force plates mounted on a moveable platform, translated unexpectedly in one of 12 directions. Peak net torque magnitudes and latencies following perturbation onset were determined as were the relative contributions of each joint to total torque production. Magnitude of net torque generated by each leg varied by perturbation direction, …


Invited Review: Heat Shock Proteins And Exercise: A Primer, Earl Noble, Kevin Milne, C.W. Melling Dec 2007

Invited Review: Heat Shock Proteins And Exercise: A Primer, Earl Noble, Kevin Milne, C.W. Melling

Jamie Melling

Heat shock proteins (HSPs) are, in general, prosurvival molecules within the cellular environment, and the overexpression of even just 1 family of HSPs can lead to protection against and improvements after a variety of stressors. Not surprisingly, a fertile area of study has grown out of effors to exploit the innate biologic behaviour of HSPs. Exercise, because of the inherent physiologic stresses associated with it, is but 1 stimulus that can result in a robust increase in various HSPs in several tissues, not the least of which happen to be the heart and skeletal muscle. The purpose of this review …


Heat Shock Proteins And Whole Body Physiology, Earl Nobe, C.W. James Melling, Kevin Milne Dec 2007

Heat Shock Proteins And Whole Body Physiology, Earl Nobe, C.W. James Melling, Kevin Milne

Jamie Melling

No abstract provided.


Stomping The Shadow: The Elevation Of Snowboarding To The Olympic Pedestal From A Jungian Perspective, Megan Popovic, Don Morrow Dec 2007

Stomping The Shadow: The Elevation Of Snowboarding To The Olympic Pedestal From A Jungian Perspective, Megan Popovic, Don Morrow

Donald Morrow

No abstract provided.


Imaging Of Transplanted Pancreatic Islets In Vivo, P. Joo Ho Tai, C. Foster, C. Hasil, C.W.J. Melling, D. White Dec 2007

Imaging Of Transplanted Pancreatic Islets In Vivo, P. Joo Ho Tai, C. Foster, C. Hasil, C.W.J. Melling, D. White

Jamie Melling

No abstract provided.