Life Sciences Commons^™

The Big Picture Of The Small Intestine, Reagan Kangas

Celebrating Scholarship and Creativity Day (2018-)

Histology is the study of microscopic tissue structures and is used to understand the function of tissues and visualize the cellular organization within them. It is an important tool in biology and medicine, used for diagnosing disease (i.e., cancers, infections, inflammatory diseases, etc.) and studying organ structure and function. The goal of this poster is to compare preparation and staining techniques, specifically paraffin versus frozen sectioning methods, along with Masson’s trichrome versus hematoxylin and eosin (H&E) staining. These methods differ in processing time, tissue preservation, and the level of detail they reveal under a microscope. This project uses small intestines …

Survival Of The Fittest: Extremophilic Actinomycetes As The Future Of Antibiotic Treatment, Ben Reddan, Kyley Nelson

Celebrating Scholarship and Creativity Day (2018-)

The antibiotic resistance crisis is an emerging global health threat. In 2019 alone, 1.27 million deaths were attributed to antibiotic-resistant pathogens, and researchers predict the problem will worsen without intervention. Methicillin-Resistant Staphylococcus aureus (MRSA) has become a primary model for this crisis because it utilizes genomic adaptations to bypass β-lactam antibiotics. Although temperate actinomycetes have historically provided the majority of clinical antibiotics, recent bioprospecting has revealed that extremophilic actinomycetes represent a critical untapped resource. These organisms exhibit several adaptations to thrive in extreme environments, which results in the production of novel secondary metabolites and resilient extracellular enzymes. This literature review …

A Two-Phase Hippocampal Code Linking Time And Distance Estimation To Action, Raphael Heldman

Electronic Theses and Dissertations 2020 - Present

A critical component of spatial navigation is the ability to estimate elapsed time or distance traveled. How the brain generates such estimates and links them to behavior remains unclear. In this thesis, we identify a previously unrecognized population coding strategy for time or distance in hippocampal CA1, a region critical for navigation and memory. Using novel behavioral paradigms in head-fixed mice combined with electrophysiological recordings, we show that this code is carried by two functionally distinct subpopulations of pyramidal neurons, termed PyrUp and PyrDown, whose firing rates evolve in opposite directions during navigation. Both populations exhibit a common two-phase dynamic: …

Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review, Abdulmutalib Allaq, Muneer M. Saleh Mohammed Saleh Alsayadi, Mustapha Salihu, Hasan M. Agha, Amena Hassan Hassan Gheeth, Fatimah Salim, Norrizah Jaafar Jaafar Sidik

AUIQ Complementary Biological System

Curcuma zedoaria Rosc. (white turmeric) is a rhizomatous medicinal plant in the Zingiberaceae family, widely used in traditional Asian medicine. In recent years, increasing scientific attention has focused on its diverse pharmacological properties and bioactive constituents. This mini review summarises current knowledge of the phytochemical composition and biological activities of C. zedoaria, with particular emphasis on its antimicrobial, antioxidant, anti-inflammatory, and anticancer effects. Phytochemical investigations using analytical techniques such as GC–MS and HPLC have revealed the presence of numerous bioactive compounds, including sesquiterpenes (example, germacrone, curzerenone, and curdione) and curcuminoids, which contribute to its therapeutic potential. Experimental studies demonstrate …

Evaluation Of Circulating Hpg80, Ca15-3, Estrogen And Progesterone As Biomarkers In Breast Cancer Patients, Safa Khaldoon, Emad Yousif, Khawla A. Kasar, Muna Bufaroosha, Rahimi Yusop

AUIQ Complementary Biological System

It is very important to find reliable biomarkers for early detection and monitoring of treatment response because breast cancer is still one of the most common cancers in women around the world. The goal of this study was to find out how clinically important different biochemical markers are in Iraqi women with breast cancer. Some of these signs are progesterone (PG), oestrogen (E2), cancer antigen 15-3 (CA15-3), and circulating progastrin (hPG80). There were 100 women in this study, and they were all between the ages of 20 and 70. There were three groups of people who took part: a healthy …

Synergistic Endocytic Receptor Ligand Receptor Protein 2 In T2dm, Wafaa Raji Alfatlawi

AUIQ Complementary Biological System

Purpose: The glycoprotein molecule known as megalin is present on the proximal renal tubular epithelial cells. With an emphasis on megalin and cubilin levels in T2DM and IR patients, an area that obviously needs more research, this study attempts to give an outline of current knowledge of megalin function in relation to vitamin D and its metabolite (vitamin D receptor and vitamin D binding protein). Materials and Methods: This was a case control comparative study conducted at a endocrine and diabetes center in AL-Imamain Kadumain teaching hospital in Baghdad-Iraq. Study subjects were divided into three groups: 25 with T2DM with …

Beyond Beneficial Margins: Four Mechanisms Linking Border Vegetation To Pest Dynamics, Jorge F. M. Cardoso, Fabiane M. Mundim

Biology Student Research

Vegetated field borders are widely promoted as tools to enhance biodiversity and strengthen biological control in agroecosystems. However, their role in pest dynamics remains conceptually fragmented and empirically inconsistent. Here, we develop a unified framework explaining how crop border vegetation influences pest populations through four interlinked ecological mechanisms. First, borders act as host reservoirs and selective filters, providing alternative hosts and overwintering habitat that enhance pest persistence across crop cycles. Second, borders modify pest colonization dynamics by shaping movement, aggregation, and host-location behavior at crop edges. Third, borders restructure multitrophic networks, simultaneously supporting natural enemies, alternative prey, vectors, and pathogens, …

Expanding The Fossil Record Of Hippopotamodon (Suidae, Artiodactyla) From The Hasnot Area, Siwalik, Pakistan, Muhammad Ilyas, Rana Mehroz Fazal, Sayyed Ghyour Abbas, Misbah Faiz, Kiran Aftab, Abdul Ghaffar, Khizar Samiullah, Luke Holbrook

STEM Student Research Symposium Posters

The suid genus Hippopotamodon with its type species H. sivalense, is well known from Upper Miocene deposits in Eurasia. Its taxonomic history has been characterized by considerable instability, including early misassignments to genera such as Sus and Potamochoerus, and subsequent reclassifications involving Propotamochoerus, Dicoryphochoerus, and Microstonyx. This confusion primarily resulted from an overreliance on variable dental and canine morphology. Subsequent systematic revisions attempted to resolve these issues by proposing synonymies among these taxa, although debate has continued regarding the relationship between Hippopotamodon and Microstonyx. Recent work supports the synonymy of these taxa based on shared diagnostic features across Eurasian material. …

Discovery And Characterization Of Three Novel Bacteriophages Infecting Arthrobacter Globiformis: Crescenzo (Ay), Gerri43 (Fr), & Roberts (Fr), Gabrielle Achinko, Maximillan Castro, Evan Chernyenko, Kelley Crescenzo, Natalie Horchuck, Jessica Lee, Mattie Mcmahon, Heidi Meehan, Sandra Orjih, Kanishka Poudel, Kaitlyn Roberts, Alex Bogush, Matthew Farber, Marina Bogush

STEM Student Research Symposium Posters

Bacteriophages are viruses that infect bacteria and are increasingly important in applications ranging from agriculture and food safety to phage therapy. In this study, we isolated and characterized three novel phages, Gerri43, Crescenzo, and Roberts, from soil samples collected in Greenwich, New Jersey, and from the Rowan University campus in Glassboro, New Jersey, using Arthrobacter globiformis as the host bacterium. Phages were recovered using standard enrichment and purification approaches. After initial isolation, multiple rounds of plaque purification and serial dilution were performed to obtain clonal populations. High-titer lysates were then prepared by flooding webbed plates. Electron microscopy showed that all …

Neurological Phenotypes Of Myotonic Dystrophy Type 1 In Drosophila Melanogaster, Carleigh M. Wood

Departmental Honors & Graduate Capstone Projects

This research investigated Drosophila melanogaster’s ability to serve as a model organism for the neurological phenotypes of Myotonic Dystrophy Type I (DM1). DM1 is caused by a CTG repeat expansion in the DMPK gene. DM1 leads to symptoms of muscle weakness and wasting, as well as decreased cerebral volume. This study aimed to determine whether DM1-affected Drosophila exhibit neurological changes, as has been observed in humans. Healthy control (CUG20) and DM1-affected Drosophila (CUG250) were generated using classical genetics. Both groups were aged three weeks prior to dissection and imaged through fluorescent microscopy. It was predicted that Drosophila melanogaster affected by …

Using The Flexon Approach To Rnai To Identify Essential Genes That Affect Gonadal Development In C. Elegans, Joyce S. Lefevers

Undergraduate Theses

To elucidate the molecular role of essential genes in the gonadal development of Caenorhabditis elegans (C. elegans) it is necessary to utilize specialized molecular techniques such that the phenotypic effects of gene knockdown can be studied while the viability of the organism is preserved. Shaffer and Greenwald (2022) developed the floxed exon (flexon), a tool that improves upon previous approaches to spatiotemporal control of gene expression. The flexon subunit is made up of an artificial exon with a stop cassette flanked by artificial introns which, when inserted into a gene of interest, prevents the expression of that gene. …

Isolation, Identification And Antibiotic-Resistance Profiling Of Bacteria Isolated From Mobile Phone Surfaces In Karbala., Kawkab Abdullah Alsaadi, Zahraa Raheem Murshidy, Dhuha Ali Hussein, Sura Abd Ali Kadhim, Kawakib Aboudi Hanoon

Karbala International Journal of Modern Science

Due to the diverse environments that mobile phones are exposed to via human handling they become reservoirs of microorganisms. The objective of the current study was to determine the level and character of bacterial contamination on mobile phones by identifying bacterial strains, and the degree of antimicrobial susceptibility. A cross-sectional study was conducted from April to July 2025 where phones belonging to 115 individuals were randomly chosen from various departments and units at Kerbala University and swabbed. The VITEK 2 automated system was used to identify bacterial taxa and test for antimicrobial susceptibility, and 50 of the swabs exhibited bacterial …

Environmental Counseling As A Proposed Discipline And Its Associated Implications And Uses, Alexandria Rion

Honors Projects

Individuals interact with their environment daily, and whether they realize it or not, these interactions can impact their health. Understanding the health impacts associated with the environment is important to human health at both an individual and population level. I am proposing a new field of environmental counseling that would incorporate principles from a variety of practices into one comprehensive discipline that can be used to promote public health. By studying populations that have had negative environmental exposures and looking at their outcomes, I was able to apply principles of environmental counseling to help determine if it would in fact …

Autoantibody Reactivity In Hidradenitis Suppurativa: Characterizing Keratinocyte And Apocrine Gland Targets Across Disease Progression And Anti-Tnf-Α Treatment, Talla Hamouche

Student Theses and Dissertations

Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory skin disease associated with impaired quality of life, representing one of the highest burdens among dermatological conditions. This debilitating disorder primarily affects apocrine-gland-bearing and flexural skin areas, most commonly the axillae, breast, buttocks, and groin. As lesions recur and new sites emerge, surgical excision does not guarantee prevention of disease reestablishment. Despite its substantial burden, HS remains among the least understood and most treatment-resistant inflammatory diseases. The mechanisms underlying this chronicity and the frequent failure of conventional anti-inflammatory therapies remain unresolved. An underappreciated autoimmune dimension may contribute to HS pathogenesis: the clonal …

Impact Of Human Disturbance On Moth Populations In Ecuador, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum

Science Seminar

Habitat disturbance in the temperate zone has been shown to negatively impact moth biodiversity and population size through a reduction in moth food resources and light pollution. Our study sought to understand how human activity impacts moth population numbers and diversity (# unique taxa) in the tropics. Specifically, we sampled moth population and diversity using light traps on two different nights in a disturbed habitat (Mera township, Ecuador) and on two nights at a nearby ecolodge situated in dense tropical forest. Significantly fewer moths were observed during trapping sessions in the township, and many fewer distinct taxa were noted when …

Patterns Of Moth Diversity In Relationship To Human Disturbance And Forest Type, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum

Science Seminar

Moths play a vital role in the health of tropical ecosystems, acting as important pollinators and food resources for a variety of species. Unfortunately, human habitat disturbance has been associated with declines in moth populations and diversity. To explore the impacts of habitat disturbance on taxonomic diversity in the tropics, we sampled moth populations at two different locations in the Pastaza Province (Mera township and an undisturbed forest at Tamandua Ecolodge). Though small in population (

The Impacts Of Wing-Flashing By Northern Mockingbirds On Foraging, Parental Care, And Reproductive Success, Anna Starman, Hayley Ponn

Science Seminar

Foraging efficiency may be enhanced by flashing patches of white wing and tail feathers and has been documented in several avian species. Northern Mockingbirds (Mimus polyglottos, NOMO) exhibit this "wing-flashing" (WF) behavior while foraging, during displays, and in response to predators. In NOMOs, WF has been hypothesized to increase foraging success, but previous findings are inconclusive. To further investigate the biological role(s) of WF behavior in NOMOs, the ventral surface of white primary feathers of male NOMOs were artificially darkened and the foraging and provisioning rates of undarkened (control) males and their mates were compared. While foraging, undarkened males performed …

Foraging Load Size And Activity In Leaf-Cutter Ants In Rural And Urban Ecuador, Natalie Tollison, Anna Starman

Science Seminar

Leaf cutter ants are important ecosystem engineers in Neotropical forests, moving a significant amount of nutrients from the forest canopy to the soil. We were interested in understanding how time (day vs. night), weather, and level of human disturbance would impact foraging activity in leaf-cutter ants (Atta spp.). To investigate, we sampled activity levels and leaf size along leaf-cutter ant trails in Mera (urban, N=17) and Tamandua (forest, N=27). During the daytime, ants in Mera carried significantly more leaves that were larger in size as well as more total items than did ants in Tamandua. Factors such as the level …

Biodiversity And Diet Patterns: Environmental Impacts On Ecuadorian Birds, Holly Hylton, Fin Bolt, Gracyn Herbst

Science Seminar

The current biodiversity crisis is of great concern, particularly to bird species in temperate and tropical areas. We examined avian biodiversity patterns in Ecuador, one of the most bird-biodiverse countries in the world (1650+ species). In January 2026, birds were surveyed (visual and auditory) for 30 minutes on consecutive days in 4 different locations that differed in the degree of human development. As expected, species richness was much higher in undisturbed locations than disturbed locations. In addition, our comparison of dietary patterns between sites showed a much higher proportion of frugivorous and insectivorous species in areas with less human disturbance …

Cultivating Curiosity Across Academic Audiences: Biology And Evidence-Based Science Communication, Nathan D. Forbes

Whittier Scholars Program

Effective Science Communicators must speak to a variety of audiences, with varying quantities of prior interest and qualities of background knowledge. The purpose of this paper was to engage differing audiences in scientific learning. This was done through a hypothetical newsletter made up for four different segments exploring a variety of topics in biology. Each segment intends to speak to a different audience with a different level of interest and/or educational level. Simplifying or analogizing without sacrificing the statistical basis of this project was of paramount importance. In the two segments targeted towards younger audiences, the primary focus was on …

Pepper Spray Exposure And The Effect On Dna Profiling Of Blood, Brandon Schmakel

Honors Projects

Pepper spray is a common self defense tool used in both law enforcement and civilian settings, with the goal of incapacitating the sprayed individual. In real casework where pepper spray was used, a red-brown stain which tested positive presumptively for blood provided no DNA profile after further testing six months later. A previous graduate student, Emma Crawn, attempted to emulate these casework conditions and instead achieved a DNA profile with slight indications of inhibition or degradation. Further analysis of active pepper spray ingredients such as Oleoresin Capsicum (OC) and Chloroacetophenone (CN) reveals that there are observed reactions, such as oxidation, …

High Performance Ae-Cnn Model Enhanced Via Gaussian Augmentation For Rssi-Dependent Indoor Positioning In Wireless Sensor Networks, Kahlaa K. Al-Nassrawy, Ghaidaa A Al-Sultany

Karbala International Journal of Modern Science

Precise indoor positioning system remains a significant challenge within Wireless Sensor Networks (WSNs) due to the instability and noise sensitivity of Received Signal Strength Indicator (RSSI) data. This paper proposes an advanced hybrid deep learning framework designed for 2D indoor localization, utilizing RSSI measurements to predict human or object position. Furthermore, to enhance the robustness of the model against signal variance and promote its generalization capability under this uncertainty, a data augmentation strategy is applied using three methods: Gaussian Noise Injection (GNI), Gaussian Mixture Model (GMM), and Bayesian Gaussian Mixture Model (BGMM). The purpose of data augmentation is to simulate …

Parasite Prevalence In Local Grasshopper Populations, Lucia B. Freund, Ali Gronquist

Research & Creative Achievement Day

Spur-throated grasshoppers (genus Melanoplus) are a common agricultural pest in North America. Spur-throated grasshoppers are also a common host to several parasitic organisms. Horsehair worms (phylum Nematomorpha) are parasitic organisms known for their ability to manipulate the behavior of its insect host, particularly grasshoppers and crickets, by urging the host to enter water so it can complete its life cycle. Along with being a host to parasitic worms, they are a frequent target of grasshopper mites. Grasshopper mites (Eutrombidium locustarum) is a short-lived parasite that can negatively influence the reproductive ability of their host. Because grasshoppers are a major agricultural …

Characterization Of Bacteria In Cattle Specimens, Jacob D. Hanson, Josie M. Tieskoetter

Research & Creative Achievement Day

Cattle nasal cavities provide a favorable environment for microbial colonization and can habit a wide population of bacteria, including opportunistic and pathogenic species. The objective of this research was to isolate, characterize, and identify bacteria present is nasal swap specimen collected from multiple calves. Samples were cultured and analyzed using selective and differential media, Gram staining, spore staining, and a range of biochemical assays. Several bacterial species were identified including the genus Corynebacterium and Streptococcus while some isolates could not be identified using classical biochemical methods alone. These results demonstrate that calf nasal specimens commonly contain diverse bacterial populations, some …

Modulating Acute Stress Reactivity: Behavioral Interventions And Caffeine-Linked Stress Physiology In College Students, Kaitlyn Smith

Honors Theses

College students frequently rely on caffeine to manage academic demands, yet its physiological and psychological effects on acute stress remain poorly understood. Although caffeine is known to increase cardiovascular arousal and self‑reported anxiety, little research has compared different caffeine sources within the same individuals or examined whether brief behavioral interventions can buffer these effects. Self‑affirmation, a short writing exercise centered on personal values, has been shown to reduce stress reactivity, but its interaction with caffeine‑induced arousal has not been tested. This within‑subjects study examines how coffee, energy drinks, and a no‑caffeine control influence acute cardiovascular and self‑reported stress responses, and …

Cognition In Pair-Living Owl Monkeys: The Role Of Partner Affiliation In The Willingness To Cooperate To Solve A Cognitive Task, Aaron J. Mencia

Electronic Theses and Dissertations 2020 - Present

Cooperative problem-solving tasks, including the loose-string paradigm, require individuals to coordinate their actions simultaneously to obtain a shared reward. These paradigms have been used extensively to assess social cognition, behavioral coordination, and partner preferences across taxa. Although the loose-string paradigm has been widely tested, it has not been applied to pair-bonded, monogamous primates such as owl monkeys (Aotus nancymaae), which exhibit affiliative behaviors including food sharing and bi-parental care. Investigating cooperation in this species may offer some clarification on whether more stable social bonds are associated with cooperative and cognitive task success as compared to those observed in …

The Effects Of Oleuropein In Olive Leaf Extract Alone Or Combined With Calcitriol On The Viability And Migration Of Human Endometrial Cells In Vitro, Katelyn Devereaux

Electronic Theses and Dissertations 2020 - Present

Endometriosis is a chronic inflammatory disease affecting approximately 10% of reproductive-aged women worldwide and is commonly associated with pelvic pain, infertility, and reduced quality of life. Current management strategies, including hormonal therapies and surgical intervention, often provide only temporary relief and are associated with recurrence and adverse effects. These limitations highlight the need for alternative, non-hormonal therapeutic approaches that target underlying inflammatory and cellular mechanisms of disease progression.

This study evaluated the effects of oleuropein, contained within an olive leaf extract, and calcitriol, the active form of vitamin D, on cellular viability and migration in immortalized human endometriotic epithelial (12Z) …

Tree Resin Effects On Environmental Microbial Growth In Tetramorium Ant Colonies, Abigail Peralta, Emma Crisman

Biology Student Scholarship

No abstract provided.

Trial Of Vaginal Microbiome Transplant To Prevent Recurrent Bacterial Vaginosis, Grace Pierson

Biology Student Scholarship

Comparative Inhibition Testing for Personalized Microbiota Selection

This case report evaluates a strategy for selecting optimal donor material for Cervicovaginal Secretion (CVS) transplantation. To identify a suitable match, CVS from four healthy, Lactobacillus-dominated donors was tested against a patient’s sample to observe microbial inhibition. Theoretically, effective donor material should produce a visible inhibition zone (halo), indicating suppressed growth of pathogenic bacteria. However, initial testing yielded unreadable results with no conclusive evidence of inhibition. Consequently, my study pivoted to analyze the direct effects of donor samples on the growth of specific pathogens, Gardnerella vaginalis and Prevotella bivia.

Altered Clock Genes Affect Fly Circadian Rhythms And Rhythms Of Cell Respiration In The Brain, Connor Enestvedt, Campbell Bridges, Anna Costello, Brenda Rodrigues, Jake Antosca

Biology Student Scholarship

Drosophila have circadian rhythms which are daily biological rhythms synchronized by an internal clock. These rhythms regulate behavioral and physiological systems within their bodies. The endogenous fly clock—made of an oscillating gene-protein feedback loop found in central pacemaker cells in the brain— sets endocrine, locomotor, and metabolic rhythms to the 24-hour Earth day The central clock signals to peripheral clocks, setting measurable rhythms. Mutations to these clock genes disrupts the oscillator, resulting in rhythm changes. In this project, we will study how flies’ circadian rhythms and cell respiration in the brain changes with mutations to clock genes. By measuring oxygen …