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Evaluation Of The Protein Recognition Properties Of Peptide Nucleic Acids, Crystal Cox Serrano
Evaluation Of The Protein Recognition Properties Of Peptide Nucleic Acids, Crystal Cox Serrano
Master's Theses
The objective is to evaluate the ability of aminoacyl-tRNA synthetases (aaRS) to recognize the non-standard nucleic acid, PNA (peptide nucleic acid). PNA has immense potential in biomedical applications due to its increased thermostability and nuclease resistance over natural nucleic acids. PNA represents a superior alternative to natural nucleic acids in many biomedical applications due to its specificity, strong binding, and nuclease resistance. This study is the initial data set that indicates PNA are recognized by translation enzymes.