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Full-Text Articles in Life Sciences

Manipulation Of Ovarian Function Significantly Influenced Trabecular And Cortical Bone Volume, Architecture And Density In Mice At Death, Jeffrey B. Mason, Boston C. Terry, Samer S. Merchant, Holly M. Mason, Mahdi Nazokkarmaher Dec 2015

Manipulation Of Ovarian Function Significantly Influenced Trabecular And Cortical Bone Volume, Architecture And Density In Mice At Death, Jeffrey B. Mason, Boston C. Terry, Samer S. Merchant, Holly M. Mason, Mahdi Nazokkarmaher

Animal, Dairy, and Veterinary Science Faculty Publications

Previously, transplantation of ovaries from young, cycling mice into old, postreproductive-age mice increased life span and decreased cardiomyopathy at death. We anticipated that the same factors that increased life span and decreased cardiomyopathy could also influence the progression of orthopedic disease. At 11 months of age, prepubertally ovariectomized and ovary-intact mice (including reproductively cycling and acyclic mice) received new 60-day-old ovaries. At death, epiphyseal bone in the proximal tibia and the distal femur and mid-shaft tibial and femoral diaphyseal bone was analyzed with micro-computed tomography. For qualitative analysis of osteophytosis, we also included mineralized connective tissue within the stifle joint. …


Feeding A Brown Midrib Corn Silage-Based Diet To Growing Beef Steers Improves Growth Performance And Economic Returns, C. S. Saunders, S. Y. Yang, J.-S. Eun, D. M. Feuz, D. R. Zobell Dec 2015

Feeding A Brown Midrib Corn Silage-Based Diet To Growing Beef Steers Improves Growth Performance And Economic Returns, C. S. Saunders, S. Y. Yang, J.-S. Eun, D. M. Feuz, D. R. Zobell

Animal, Dairy, and Veterinary Science Faculty Publications

A feedlot experiment was performed to determine growth performance, ruminal fermentation characteristics, and economic returns for growing beef steers when fed a brown midrib corn silage-based total mixed ration (BMRT) compared with a conventional corn silage-based total mixed ration (CCST). Twenty-four Angus crossbred steers (initial body weight=258±23.2 kg) in individual pens were used in a completely randomized design (n=12). Intake of dry matter was not different between the treatments. Steers fed the BMRT tended to have greater average daily gain (1.54 vs. 1.42 kg d−1; P=0.09) and gain-to-feed ratio (0.165 vs. 0.146; P=0.07) compared with those fed the CCST. Feeding …


Cytokine Gene Expression In The Maternal-Fetal Interface In Somatic Cell Nuclear Transfer Pregnancies In Small Ruminants, Heloisa M. Rutigliano, Amanda Wilhelm, Justin Hall, Bi Shi, Qinggang Meng, Rusty Stott, Tom D. Bunch, Kenneth L. White, Christopher J. Davies, Irina A. Polejaeva Oct 2015

Cytokine Gene Expression In The Maternal-Fetal Interface In Somatic Cell Nuclear Transfer Pregnancies In Small Ruminants, Heloisa M. Rutigliano, Amanda Wilhelm, Justin Hall, Bi Shi, Qinggang Meng, Rusty Stott, Tom D. Bunch, Kenneth L. White, Christopher J. Davies, Irina A. Polejaeva

Animal, Dairy, and Veterinary Science Faculty Publications

The present retrospective study investigates pregnancy rates, incidence of pregnancy losses and large offspring syndrome (LOS), and immune-related gene expression of sheep and goat somatic cell nuclear transfer (SCNT) pregnancies. We hypothesized that significantly higher pregnancy losses observed in sheep SCNT pregnancies compared to goats are due to the increased amounts of T-helper 1 cytokines and pro-inflammatory mediators at the maternal-fetal interface. Sheep and goat SCNT pregnancies were generated using the same procedure. Control pregnancies were established by natural breeding. Although SCNT pregnancy rates at 45 days were similar in both species, pregnancy losses between 45 and 60 days and …


The Broad-Spectrum Antiviral Favipiravir Protects Guinea Pigs From Lethal Lassa Virus Infection Post-Disease Onset, David Safronetz, Kyle Rosenke, Cynthia Martellaro, Heinz Feldmann, Jonna B. Westover, Brian B. Gowen, Atsushi Okumura, Yousuke Furuta, Takashi Komeno, Greg Saturday, Joan Geisbert, Thomas W. Geisbert Oct 2015

The Broad-Spectrum Antiviral Favipiravir Protects Guinea Pigs From Lethal Lassa Virus Infection Post-Disease Onset, David Safronetz, Kyle Rosenke, Cynthia Martellaro, Heinz Feldmann, Jonna B. Westover, Brian B. Gowen, Atsushi Okumura, Yousuke Furuta, Takashi Komeno, Greg Saturday, Joan Geisbert, Thomas W. Geisbert

Animal, Dairy, and Veterinary Science Faculty Publications

With up to 500,000 infections annually, Lassa virus (LASV), the cause of Lassa fever, is one of the most prevalent etiological agents of viral hemorrhagic fever (VHF) in humans. LASV is endemic in several West African countries with sporadic cases and prolonged outbreaks observed most commonly in Sierra Leone, Liberia, Guinea and Nigeria. Additionally several cases of Lassa fever have been imported into North America, Europe and Asia making LASV a global threat to public health. Despite this, currently no approved therapeutic or vaccine exists to treat or prevent LASV infections. Here, using a passaged strain of LASV that is …


The Broad-Spectrum Antiviral Favipiravir Protects Guinea Pigs From Lethal Lassa Virus Infection Post-Disease Onset, David Safronetz, Kyle Rosenke, Jonna B. Westover, Cynthia Martellaro, Atsushi Okumura, Yousuke Furuta, Joan Geisbert, Greg Saturday, Takashi Komeno, Thomas W. Geisbert, Heinz Feldmann, Brian B. Gowen Oct 2015

The Broad-Spectrum Antiviral Favipiravir Protects Guinea Pigs From Lethal Lassa Virus Infection Post-Disease Onset, David Safronetz, Kyle Rosenke, Jonna B. Westover, Cynthia Martellaro, Atsushi Okumura, Yousuke Furuta, Joan Geisbert, Greg Saturday, Takashi Komeno, Thomas W. Geisbert, Heinz Feldmann, Brian B. Gowen

Plants, Soils, and Climate Faculty Publications

With up to 500,000 infections annually, Lassa virus (LASV), the cause of Lassa fever, is one of the most prevalent etiological agents of viral hemorrhagic fever (VHF) in humans. LASV is endemic in several West African countries with sporadic cases and prolonged outbreaks observed most commonly in Sierra Leone, Liberia, Guinea and Nigeria. Additionally several cases of Lassa fever have been imported into North America, Europe and Asia making LASV a global threat to public health. Despite this, currently no approved therapeutic or vaccine exists to treat or prevent LASV infections. Here, using a passaged strain of LASV that is …


Unusual Behavior In Parental Care By A House Wren (Troglodytes Aedon): Post Fledging Use Of An Old Nest During Cold Nights, Micah N. Scholer Sep 2015

Unusual Behavior In Parental Care By A House Wren (Troglodytes Aedon): Post Fledging Use Of An Old Nest During Cold Nights, Micah N. Scholer

Articles

I report on the unusual behavior of an adult House Wren (Troglodytes aedon) leading recently fledged young back to the nest for two consecutive nights. The ambient temperature reached below 0°C during both nights. Despite disadvantages associated with remaining in the nest, this observation suggests that adult birds may assess trade-offs between perceived risks versus the benefits of engaging in other activities, in this case roosting communally for thermoregulation.


Interdisciplinary Modeling For Water-Related Issues Graduate Course, Laurel Saito, Alexander Fernald, Timothy Link Jul 2015

Interdisciplinary Modeling For Water-Related Issues Graduate Course, Laurel Saito, Alexander Fernald, Timothy Link

All ECSTATIC Materials

The science and management of aquatic ecosystems is inherently interdisciplinary, with issues associated with hydrology, atmospheric science, water quality, geochemistry, sociology, economics, environmental science, and ecology. Addressing water resources issues in any one discipline invariably involves effects that concern other disciplines, and attempts to address one issue often have consequences that exacerbate existing issues or concerns, or create new ones (Jørgensen et al. 1992; Lackey et al. 1975; Straskraba 1994) due to the strongly interactive nature of key processes (Christensen et al. 1996). Thus, research and management of aquatic ecosystems must be interdisciplinary to be most effective, but such truly …


How Does Variation In Winter Weather Affect Deer-Vehicle Collision Rates, Daniel D. Olson, John A. Bissonette, Patricia C. Cramer, Patrick J. Jackson, Kevin D. Bunnell, Daniel C. Coster Mar 2015

How Does Variation In Winter Weather Affect Deer-Vehicle Collision Rates, Daniel D. Olson, John A. Bissonette, Patricia C. Cramer, Patrick J. Jackson, Kevin D. Bunnell, Daniel C. Coster

Wildland Resources Faculty Publications

Understanding how deer move in relationship to roads is critical, because deer are in vehicle collisions, and collisions cause vehicle damage, as well as human injuries and fatalities. In temperate climates, mule deer Odocoileus hemionus have distinct movement patterns that affect their spatial distribution in relationship to roads. In this paper, we analyzed deer movements during two consecutive winter seasons with vastly different conditions to determine how deer—vehicle collision rates responded. We predicted that deer—vehicle collision rates would be higher when precipitation and snow depth were higher. We used meteorological data from local weather stations to describe temperature, precipitation and …


Rift Valley Fever Virus Infection In Golden Syrian Hamsters, Dionna Scharton, Arnaud J. Van Wettere, Kevin W. Bailey, Zachary Vest, Jonna B. Westover, Venkatraman Siddharthan, Brian B. Gowen Jan 2015

Rift Valley Fever Virus Infection In Golden Syrian Hamsters, Dionna Scharton, Arnaud J. Van Wettere, Kevin W. Bailey, Zachary Vest, Jonna B. Westover, Venkatraman Siddharthan, Brian B. Gowen

Animal, Dairy, and Veterinary Science Faculty Publications

Rift Valley fever virus (RVFV) is a formidable pathogen that causes severe disease and abortion in a variety of livestock species and a range of disease in humans that includes hemorrhagic fever, fulminant hepatitis, encephalitis and blindness. The natural transmission cycle involves mosquito vectors, but exposure can also occur through contact with infected fluids and tissues. The lack of approved antiviral therapies and vaccines for human use underlies the importance of small animal models for proof-of-concept efficacy studies. Several mouse and rat models of RVFV infection have been well characterized and provide useful systems for the study of certain aspects …


Investigating The Filled Gel Model In Cheddar Cheese Through Use Of Sephadex Beads, L. M. Barden, J. A. Osborne, Donald J. Mcmahon, E. A. Foegeding Jan 2015

Investigating The Filled Gel Model In Cheddar Cheese Through Use Of Sephadex Beads, L. M. Barden, J. A. Osborne, Donald J. Mcmahon, E. A. Foegeding

Nutrition, Dietetics, and Food Sciences Faculty Publications

Cheese can be modeled as a filled gel whereby milkfat globules are dispersed in a casein gel network. We determined the filler effects using Sephadex beads (GE Healthcare Life Sciences, Pittsburgh, PA) as a model filler particle. Ideally, such a model could be used to test novel filler particles to replace milkfat in low-fat cheese. Low-filler (6% particles), reduced-filler (16%), and full-filler (33%) cheeses were produced using either Sephadex beads of varying sizes (20 to 150 μm diameter) or milkfat. Small- and large-strain rheological tests were run on each treatment at 8, 12, and 18 wk after cheese manufacturing. Differences …


Characterization Of Brd4 During Mammalian Post-Meiotic Sperm Development, Jessica M. Bryant, Greg Donahue, Xiaoshi Wang, Mirella Meyer-Ficca, Lacey J. Luense, Angela H. Weller, Marisa S. Bartolomei, Gerd A. Blobel, Ralph G. Meyer, Benjamin A. Garcia, Shelley L. Berger Jan 2015

Characterization Of Brd4 During Mammalian Post-Meiotic Sperm Development, Jessica M. Bryant, Greg Donahue, Xiaoshi Wang, Mirella Meyer-Ficca, Lacey J. Luense, Angela H. Weller, Marisa S. Bartolomei, Gerd A. Blobel, Ralph G. Meyer, Benjamin A. Garcia, Shelley L. Berger

Animal, Dairy, and Veterinary Science Faculty Publications

During spermiogenesis, the post-meiotic phase of mammalian spermatogenesis, transcription is progressively repressed as nuclei of haploid spermatids are compacted through a dramatic chromatin reorganization involving hyper-acetylation and replacement of most histones with protamines. Although BRDT functions in transcription and histone removal in spermatids, it is unknown whether other BET family proteins play a role. Immunofluorescence of spermatogenic cells revealed BRD4 in a ring around the nuclei of spermatids containing hyper-acetylated histones. The ring lies directly adjacent to the acroplaxome, the cytoskeletal base of the acrosome, previously linked to chromatin reorganization. The BRD4 ring does not form in acrosomal mutant mice. …


Pathology In Practice - Fascioliasis In A Dahl Sheep, David J. Wilson, T. J. Baldwin, Kerry A. Rood Jan 2015

Pathology In Practice - Fascioliasis In A Dahl Sheep, David J. Wilson, T. J. Baldwin, Kerry A. Rood

Animal, Dairy, and Veterinary Science Faculty Publications

In early fall 2012, a 48-kg (106-lb) sexually intact male Dahl ram in fair body condition was found dead; the owner observed no clinical signs prior to death. The ram was part of a flock of 50 game animals used for high-fence hunting that was moved among pastures in Idaho, Utah, and Montana. The ram was housed primarily on flood-irrigated pasture in common with approximately 170 captive Rocky Mountain elk (Cervus canadensis). The owner reported that 12 other sheep had died over the past year without observed clinical signs, but none were submitted for postmortem examination. Both sheep and elk …


Dairy Herd - Level Prevalence Of Johne's Disease And Bvd In The Intermountain West Of The U.S.A. And Farm Management Practices And Characteristics For Test-Positive Herds, David J. Wilson, Kerry A. Rood, C. Whitehouse, J. Bunnell, G. M. Goodell, T. M. Byrem Jan 2015

Dairy Herd - Level Prevalence Of Johne's Disease And Bvd In The Intermountain West Of The U.S.A. And Farm Management Practices And Characteristics For Test-Positive Herds, David J. Wilson, Kerry A. Rood, C. Whitehouse, J. Bunnell, G. M. Goodell, T. M. Byrem

Animal, Dairy, and Veterinary Science Faculty Publications

Herd-level prevalence of Mycobacterium avium subsp. paratuberculosis (MAP), causative agent of Johne’s disease (JD) and Bovine Viral Diarrhea (BVD) virus were estimated on dairy farms in Utah. Duplicate milks were collected at 3-4 day intervals on 5 dates from each bulk tank on participating farms. Samples were tested at separate laboratories for BVD (real-time, RT-PCR) and for JD/MAP (ELISA and qPCR). 151/209 (72%) eligible dairy farms participated. Farms detected positive were: 58 JD (38%) and 14 BVD (9%); 5 farms had both diseases. Follow up visited farms’ (n=22) means, medians: 778,420 milking cows; 20,052 lbs, 20,311 lbs 305d milk; 175,545/ml, …