Industrial Engineering Commons^™

Bridging Models And Real-World Performance: Capturing Represented, Hidden, And Unrepresented Dynamics In Complex Systems, Dixizi Liu

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Complex systems often depend on adaptive performance that is difficult to capture using structured data or formal models alone. This dissertation asks how predictive modeling, coordination-cost measurement, and simulation can be integrated to better represent the visible, hidden, and unrepresented dynamics that shape real-world system performance.

Sterile Processing Departments (SPDs) provide the empirical context for this work because they support safe and timely surgical care while operating under high workload variability, time pressure, and tight coordination with operating rooms. Hospitals rely on SPDs to clean, assemble, sterilize, and deliver surgical instrument trays so surgeries can start on time and proceed …

Human-Centered Design Of Extended Reality For Learning Adoption, Effectiveness, And Collaborative Training Performance, Bhargav Upadhyay

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Extended reality (XR) technologies like virtual reality (VR) and augmented reality (AR) can be used for technical training to help students learn and practice complex tasks in a safe digital environment. Despite known benefits evidence is required to explore the effectiveness of these technologies to support student learning outcomes. Furthermore, technical training programs need evidence about when these tools improve learning, what are the barriers to adoption of these technologies, and how training should be designed by leveraging these technologies. This dissertation examined how XR technologies can support higher education and workforce training, specifically focusing on barriers and facilitators to …

Multi-Stage Stochastic Programming For Disaster Relief Logistics Under Forecast Uncertainty, Sudhan Bhattarai

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Hurricanes are among the most destructive annual disasters in the United States, presenting interdependent challenges for evacuation planning and relief-supply logistics. Coordinating evacuation and relief operations is crucial to ensure the timely and effective movement of at-risk populations and the delivery of essential supplies. This dissertation develops and evaluates three progressively advanced multi-stage stochastic programming (MSSP) frameworks that integrate evacuation and relief-item pre-positioning while explicitly accounting for uncertainty in hurricane forecasts.

Chapter 1 introduces a fully adaptive MSSP model for the integrated hurricane relief logistics and evacuation planning (IHRLEP) problem. The model simultaneously optimizes evacuation flows and inventory pre-positioning over …

Understanding The Elements Of Sterile Processing Workflow: Or, Sterilization And Personnel, Sayed Rezwanul Islam

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The Sterile Processing Department (SPD), also known as the Central Sterile Services Department (CSSD), is an essential part of hospitals and healthcare facilities and is responsible for ensuring the cleanliness, sterility, and proper functioning of medical instruments. Sterile processing departments (SPDs) are key drivers of productivity, effectiveness, safety, and infection control in hospitals. A well-designed SPD workflow can enhance patient safety, reduce operating room (OR) delays, and improve productivity. To understand the flow of sterile processing and interactions between the OR and SPD, process maps and task analyses were developed through direct observations of the basic SPD functions: decontamination, assembly, …

Data-Driven Stochastic Programming For Disaster Housing Logistics Planning, Sheng-Yin Chen

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This dissertation develops an integrated modeling and solution framework for direct temporary disaster housing logistics under demand uncertainty. The proposed framework addresses the problem from short-term, long-term, and computational perspectives. First, a two-stage chance-constrained stochastic programming (TSCC) model is developed for short-term housing logistic planning, with demand scenarios generated via a data-driven spatial regression model that captures the relationship between housing demand, hazard exposure, and socioeconomic factors. A case study based on Hurricane Ian demonstrates that the TSCC model outperforms deterministic and traditional scenario-based models in both solution quality and robustness. Second, to address long-term housing logistics planning, a multi-horizon …

Advancing Life Cycle Assessment For Environmental Sustainability Of Carbon Fiber-Reinforced Polymer Composites (Cfrps)), Hao Chen

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Carbon fiber-reinforced polymer composites (CFRPs) have emerged as promising materials, particularly for lightweight applications, with the potential to reduce environmental impacts across multiple sectors, including automotive, aerospace, and renewable energy. However, fully realizing their sustainability potential requires a more comprehensive and context-specific understanding of their environmental performance throughout the entire life cycle—from raw material production to end-of-life management.

This dissertation advances life cycle assessment (LCA) practices for CFRPs by addressing key challenges across multiple phases of the CFRP life cycle. First, I conducted a critical review and meta-analysis of carbon fiber manufacturing, revealing substantial variability in reported data on energy …

Replacement Optimization For Offshore Wind Turbine Farms, Morteza Soltani

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This dissertation is concerned with devising optimal replacement policies for offshore wind turbines with a focus on minimizing the costs associated with major component replacements and production losses due to downtime. Like their onshore counterparts, offshore wind turbines are subject to progressive degradation due to normal operations, as well as the influence of dynamic environmental conditions that influence their rate of degradation. Due to their proximity, wind farm turbines share common environmental conditions, as well as specialized maintenance resources. Their common exposure to the environment and need to share resources introduce both stochastic and economic dependence between the wind turbines. …

Human Comfort Modeling, Measurement, And Improvement In Human–Robot Collaboration, Yuchen Yan

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A dissertation is proposed to explore human comfort in human-robot collaboration (HRC) through modeling, prediction, and enhancement methodologies. Human comfort is a crucial yet underexplored factor in HRC, directly influencing task efficiency, trust, and overall collaboration effectiveness. Understanding the influential factors, developing computational models, and refining methods to improve human comfort in HRC are essential steps toward advancing the field of collaborative robotics. To address these challenges, multiple studies have been conducted. A series of experimental studies were performed to investigate how robot motion-based parameters affect human comfort in HRC. These studies examined both analytical comfort modeling approaches and physiological …

An Emergency Response System To Assist The Movement Of Vehicles During Emergency Operations In Urban Transportation Networks, Jamal Nahofti Kohneh

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Emergency responders need to arrive at the emergency scene as soon as possible, but operating vehicles under emergency conditions can pose a risk to both the responders and other road users, potentially resulting in crashes or delays in emergency operations. In this research, an emergency response system is proposed to assist emergency and non-emergency response vehicles (ERVs and non-ERVs) during emergency operations in a connected vehicle environment. This system collects the information from connected ERVs and non-ERVs, utilizes this information as inputs in the proposed models, and sends instruction messages back to vehicles. The proposed models provide the fastest ERV …

Identification And Validation Of A Measurement Of Emergency Physician Workload During End Of Shift Patient Handoffs, Steven Foster

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Recent increases in emergency physician (EP) workload have been identified as contributors to increased EP burnout, increased staff attrition, decreased patient safety, and increased patient admission rates. Patient handoffs have been extensively researched as critical points in patient care, with existing research primarily focusing on communication errors and interventions designed to standardize handoff communication protocols.

While end of shift handoffs in hospital emergency departments (EDs) intuitively represent a transfer of patient caseload from an outgoing EP to an incoming EP, there is a fundamental lack of literature examining how such handoffs contribute to EP workload, and a similar lack of …

Opioid Overdose Epidemic Modeling, Chelsea Spence

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The opioid overdose crisis in the United States has led to thousands of lost lives and thousands more people struggling with opioid dependence. Disease modeling allows researchers to examine the course that the disease may take and to investigate policies to determine the effects they may have. Disease models can be used to model non-communicable diseases and have been used to study opioid use disorder. Many types of disease models exist with their own inherent benefits and drawbacks.

In this dissertation, we provide a scoping review of the disease models that have been used to study the opioid overdose epidemic. …

Variability In Anesthesia And Its Implications For Improving Patient Safety, Joshua Michael Biro

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Improving patient safety in anesthesia has proven to be an arduous and challenging task. Despite the many strategies and interventions to improve patient safety that have been employed, patient harm in anesthesia remains a problem. The struggle to reduce patient harm in anesthesia is both attributable to and representative of the complexity of the anesthesia system. In navigating this complex system, anesthesia providers have different approaches to how they accomplish their work, which results in variability in anesthesia practice. This variability provides an immense challenge to designing and implementing efforts to improve patient safety, as rigid interventions are often met …

Studying Pedestrian’S Unmarked Midblock Crossing Behavior On A Multilane Road When Interacting With Autonomous Vehicles Using Virtual Reality, Fengjiao Zou

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This dissertation focuses on the challenge of pedestrian interaction with autonomous vehicles (AVs) at unmarked midblock locations where the right-of-way is unspecified. A virtual reality (VR) simulation was developed to replicate an urban unmarked midblock environment where pedestrians cross a four-lane arterial roadway and interact with AVs. One research goal is to investigate the impact of roadway centerline features (undivided, two-way left-turn lane, and median) and AV operational schemes portrayed through on-vehicle signals (no signal, yellow negotiating indication, and yellow/blue negotiating/no-yield indications) on pedestrian crossing behavior. Results demonstrate that both roadway centerline design features and AV operations and signaling show …

Essays On Perioperative Services Problems In Healthcare, Amogh S. Bhosekar

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One of the critical challenges in healthcare operations management is to efficiently utilize the expensive resources needed while maintaining the quality of care provided. Simulation and optimization methods can be effectively used to provide better healthcare services. This can be achieved by developing models to minimize patient waiting times, minimize healthcare supply chain and logistics costs, and maximize access. In this proposal, we study some of the important problems in healthcare operations management. More specifically, we focus on perioperative services and study scheduling of operating rooms (ORs) and management of necessary resources such as staff, equipment, and surgical instruments. We …

Design And Operations Of A New Facility In A Next Generation Logistic System Based On Horizontal Collaboration, Dilhani Marasinghe

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The growing amount of freight combined with systemic inefficiencies are stressing current logistic systems. Including horizontal collaboration in the future could provide significant help but this strategy will require several new types of facilities. The most flexible type of horizontal collaboration, however, required freight routing decisions to be made dynamically, in real time, and based on last minute information. This research explores one new facility type operating in this environment that handles a high throughput of pallets or pallet-like containers. A key design feature is how much storage these facilities should have to better coordinate outbound loads. The approach taken …

Optimal Global Supply Chain And Warehouse Planning Under Uncertainty, Avnish Kishor Malde

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A manufacturing company's inbound supply chain consists of various processes such as procurement, consolidation, and warehousing. Each of these processes is the focus of a different chapter in this dissertation.

The manufacturer depends on its suppliers to provide the raw materials and parts required to manufacture a finished product. These suppliers can be located locally or overseas with respect to the manufacturer's geographic location. The ordering and transportation lead times are shorter if the supplier is located locally. Just In Time (JIT) or Just In Sequence (JIS) inventory management methods could be practiced by the manufacturer to procure the raw …

Adaptive Design And Flexible Approval Of Clinical Trials, Saeid Delshad Sisi

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Dose-finding clinical trials are among the most critical cornerstones of the healthcare system. In this broad research area, there are many decision making problems that are extremely challenging to address. However, a small improvement may result in significant benefits to the society. Dose-finding clinical trials are extremely expensive and require multiple time-consuming and complicated R&D phases. Despite all the costs and the long time these trials need to conclude (on average over ten years for each new drug/technology), only less than 15\% of these trials successfully end up in a new approved drug entering the market. This problem is even …

Selected Interdiction Games With Uncertain, Risk-Averse, And Simultaneous Play Considerations, Di H. Nguyen

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This dissertation examines two network interdiction problems: a shortest-path interdiction problem under uncertainty and a network interdiction problem in a simultaneous game. Both problems happen in two stages over a directed network, and involve a leader and a follower who have opposing interests.

In the first problem, the leader acts first to lengthen a subset of arcs, and a follower acts second to select a shortest path across the network. The cost for a follower’s arc consists of a base cost if the arc is not interdicted, plus an additional cost that is incurred if the arc is interdicted. The …

Design And Analysis Of Efficient Freight Transportation Networks In A Collaborative Logistics Environment, Vishal Badyal

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The increase in total freight volumes, reducing volume per freight unit, and delivery deadlines have increased the burden on freight transportation systems of today. With the evolution of freight demand trends, there also needs to be an evolution in the freight distribution processes. Today's freight transportation processes have a lot of inefficiencies that could be streamlined, thus preventing concerns like increased operational costs, road congestion, and environmental degradation. Collaborative logistics is one of the approaches where supply chain partners collaborate horizontally or/and vertically to create a centralized network that is more efficient and serves towards a common goal or objective. …

Examining The Impact Of Design Features Of Electronic Health Records Patient Portals On The Usability And Information Communication For Shared Decision Making, Rong Yin

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The use of the Electronic Health Records (EHR) patient portal has been shown to be effective in generating positive outcomes in patients’ healthcare, improving patient engagement and patient-provider communication. Government legislation also required proof of its meaningful use among patients by healthcare providers. Typical patient portals also include features such as health information and patient education materials. However, little research has examined the specific use of patient portals related to individuals with specific diseases such as inflammatory bowel diseases (IBDs). IBDs are life-long, not curable, chronic diseases that can impact the whole population. Individuals with IBDs may have higher needs …

A Study Of Scheduling Problems With Sequence Dependent Restrictions And Preferences, Nitin Srinath

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In some applications like fabric dying, semiconductor wafer processing, and flexible manufacturing, the machines being used to process jobs must be set up and serviced frequently. These setup processes and associated setup times between jobs often depend on the jobs and the sequence in which jobs are placed onto machines. That is, the scheduling of jobs on machines must account for the sequence-dependent setup times as well. These setup times can be a major factor in operational costs. In fabric dyeing processes, the sequence in which jobs are processed is also important for quality, i.e., there is a strong preference …

Double Tolerance Design In Stochastic Production Environments, Di Liu

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In a production process, it is impossible to produce parts with exact specifications. Thus, specific ranges, i.e., tolerances, are commonly employed to define intervals for the quality characteristics of conforming products (Wu & Tang (1998)). Usually, a product is deemed conforming when the measurement of the quality characteristic falls within the tolerance. If the measurement falls outside the tolerance, the product is nonconforming and it can be reworked or scrapped. One of the important engineering problems commonly faced by practitioners is to determine optimal engineering tolerances to be used in production. As a result, tolerance design techniques are widely used …

Multistage Stochastic Programming: Algorithms, Modelling And Applications, Murwan Siddig

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This dissertation comprises four di˙erent topics related to multistage stochastic program-ming (MSP) algorithms, modeling, and applications.

First, we extend the adaptive partition-based approach for solving two-stage stochastic programs with a fixed recourse matrix and a fixed cost vector to the MSP setting, where the stochastic process is assumed to be stage-wise independent. The proposed algorithms integrate the adaptive partition-based strategy with a popular approach for solving multistage stochastic programs, the stochastic dual dynamic programming (SDDP) algorithm, according to two main strategies. These two strategies are distinct from each other in the manner by which they refine the partitions during the …

Control Of Infectious Diseases In A Metapopulation, Ceyda Best

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With the motivation of the complex infectious disease control problem, we provide two different approaches to model the resource allocation problem to control an epidemic in a metapopulation. All of our models utilize a detailed stochastic simulation model that is validated with the data from the 2014 Ebola epidemic. This simulation model provides a tool for comparing the performance of different policies.

The first model defines a dynamic allocation problem, which is modeled by a Markov Decision Process, and aims to find feasible and effective quarantine policies to control an epidemic with limited resources. We assume that the populations share …

Nursing Interruption Dynamics: The Impact Of Work System Factors, Yushi Yang

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Interruptions occur frequently in healthcare work systems. Hands-free Communication Devices (HCDs) were implemented in healthcare work systems to support the interruption process. However, from a sociotechnical systems perspective, HCDs may introduce new complications and unintended consequences to the work system. Research gaps exist in investigating the complexity of HCD interruptions in the real-world context. This dissertation aims to understand HCD interruption dynamics in the nursing work systems, using qualitative research methods. The first study examined the major differences between face-to-face and HCD-mediated interruptions, based on 30 hours of field observations in the acute care setting. Three major differences included: (1) …

Integrating Visual Mnemonics And Input Feedback With Passphrases To Improve The Usability And Security Of Digital Authentication, Kevin Juang

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The need for both usable and secure authentication is more pronounced than ever before. Security researchers and professionals will need to have a deep understanding of human factors to address these issues. Due to their ubiquity, recoverability, and low barrier of entry, passwords remain the most common means of digital authentication. However, fundamental human nature dictates that it is exceedingly difficult for people to generate secure passwords on their own. System-generated random passwords can be secure but are often unusable, which is why most passwords are still created by humans. We developed a simple system for automatically generating mnemonic phrases …

Two-Stage Methodology For Managing And Controlling Material Flow Between Multiple Construction Projects, Fatmah Almazkoor

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There is a strong connection between managing and controlling material flow in a supply chain and its performance. While this is true in all supply chains, it is particularly true in the construction supply chain (CSC) where the total demand for parts is finite, the storage space available can be small, and the variability in consumption is high. On the other hand, effectively controlling the CSC can have a significant impact on controlling risk and buffering their impact so that projects stay on schedule and within budget. Currently, a common control of the CSC is with a push-based material ordering …

Strategies To Improve The Efficiency Of Emergency Medical Service (Ems) Systems Under More Realistic Conditions, Kanchala Sudtachat

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Emergency medical service (EMS) systems provide medical care to pre-hospital patients who need rapid response and transportation. This dissertation proposes a new realistic approach for EMS systems in two major focuses: multiple unit dispatching and relocation strategies. This work makes recommendations for multiple-unit dispatch to multiple call priorities based on simulation optimization and heuristics. The objective is to maximize the expected survival rate. Simulation models are proposed to determine the optimization. A heuristic algorithm is developed for large-scale problems. Numerical results show that dispatching while considering call priorities, rather than always dispatching the closest medical units, could improve the effectiveness …

Characteristics And Contributing Factors Of Emergency Vehicle Crashes, Naji Abdelwanis

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The purpose of this study is to determine the contributing factors and characteristics associated with emergency vehicle(EV) crashes in order to generate insights about the emergency crashes. This dissertation consists of three approaches to address the purpose. In the first analysis a binary logistic regression model was used to identify the critical factors associated with EV crashes that resulted in fatality compared to those that did not. In the second analysis, an ordered regression model was used to identify critical factors that contributed to the severity of injuries that EV occupants experience in crashes as well as the effect of …

Predicting Surgical Flow Disruption Recovery In Cardiothoracic Operating Rooms, Gary Palmer Ii

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Disruptions are common occurrences in a variety of healthcare settings and early research has shown that they are likely contributors to medical errors. For this reason, healthcare researchers have focused on studying and understanding the nature of Surgical Flow Disruptions (SFDs) to increase patient safety and quality of care within the operating room (OR). Many researchers have used simplistic taxonomies to collect and categorize the types of SFD that occur within the OR. Others have gone further to study SFD recovery and have link unrecovered and recovered SFD to minor and major adverse events experienced by patients. This dissertation, focused …