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Articles 61 - 90 of 100
Full-Text Articles in Operations Research, Systems Engineering and Industrial Engineering
Research And Development Effort In Developing The Optimal Formulations For New Tablet Drugs, Zhe Li
Research And Development Effort In Developing The Optimal Formulations For New Tablet Drugs, Zhe Li
All Dissertations
Seeking the optimal pharmaceutical formulation is considered one of the most critical research components during the drug development stage. It is also an R&D effort incorporating design of experiments and optimization techniques, prior to scaling up a manufacturing process, to determine the optimal settings of ingredients so that the desirable performance of related pharmaceutical quality characteristics (QCs) specified by the Food and Drug Administration (FDA) can be achieved. It is widely believed that process scale-up potentially results in changes in ingredients and other pharmaceutical manufacturing aspects, including site, equipment, batch size and process, with the purpose of satisfying the clinical …
Algebraic Approaches To Stochastic Optimization, Katherine Hastings
Algebraic Approaches To Stochastic Optimization, Katherine Hastings
All Dissertations
The dissertation presents algebraic approaches to the shortest path and maximum flow problems in stochastic networks. The goal of the stochastic shortest path problem is to find the distribution of the shortest path length, while the goal of the stochastic maximum flow problem is to find the distribution of the maximum flow value. In stochastic networks it is common to model arc values (lengths, capacities) as random variables. In this dissertation, we model arc values with discrete non-negative random variables and shows how each arc value can be represented as a polynomial. We then define two algebraic operations and use …
A Comprehensive Human Factors Analysis Of Off-Duty Motor Vehicle Crashes In The United States Military, Rebecca Iden
A Comprehensive Human Factors Analysis Of Off-Duty Motor Vehicle Crashes In The United States Military, Rebecca Iden
All Dissertations
Researchers have always had great interest in traffic safety and the phenomenon of motor vehicle crashes (MVCs). Though scores of service members are severely injured or killed in off-duty MVCs each year, few studies have addressed the MVC phenomenon within the military population and none have conducted a comprehensive evaluation of the causal factors associated with MVCs involving military personnel.
The main purpose of this dissertation was to gain a greater understanding of the causal factors associated with serious and fatal off-duty personal MVCs for military service members with the ultimate goal of preventing future losses. The HFACS-MVC framework was …
Extending Origami Technique To Fold Forming Of Sheet Metal Products, Ala Qattawi
Extending Origami Technique To Fold Forming Of Sheet Metal Products, Ala Qattawi
All Dissertations
This dissertation presents a scientific based approach for the analysis of folded sheet metal products. Such analysis initializes the examination in terms of topological exploration using set of graph modeling and traversal algorithms. The geometrical validity and optimization are followed by utilizing boundary representation and overlapping detection during a geometrical analysis stage, in this phase the optimization metrics are established to evaluate the unfolded sheet metal design in terms of its manufacturability and cost parameters, such as nesting efficiency, total welding cost, bend lines orientation, and maximum part extent, which aides in handling purposes. The proposed approach evaluates the design …
The Effects Of Weather Recognition Training On General Aviation Pilot Situation Assessment And Tactical Decision Making When Confronted With Adverse Weather Conditions, Chansik Kim
All Dissertations
Previous general aviation (GA) accident studies showed that decision errors were more associated with fatal GA accidents than other kinds of human errors, and weather related accidents, especially continued visual flight rules (VFR) flight into instrument meteorological conditions (IMC), remained the major cause of fatal GA accidents. Thus, finding the underlying causes of GA pilots' decision errors and continued VFR flight into adverse weather conditions are needed to reduce weather related GA accidents as well as fatal GA accidents.
Causal factors and hypotheses of weather related GA accidents show that knowledge, experience, motivation, and weather information frequently have been referred …
Metaheuristics For Hub Location Models, Ornurai Sangsawang
Metaheuristics For Hub Location Models, Ornurai Sangsawang
All Dissertations
In this research, we propose metaheuristics for solving two p-hub median problems.. The first p-hub median problem, which is NP-hard, is the uncapacitated single p-hub median problem (USApHMP). In this problem, metaheuristics such as genetic algorithms, simulated annealing and tabu search, are applied in different types of representations. Caching is also
applied to speed up computational time of the algorithms. The results clearly demonstrate that tabu search with a permutation solution representation, augmented with caching is the highest performing method, both in terms of solution quality and computational time among these algorithms for the USApHMP. We also investigate the performance …
Anticipating U.S. Population-Level Health And Economic Impacts Using Discrete-Event Simulation To Guide Health Policy Decisions, Odette Reifsnider
Anticipating U.S. Population-Level Health And Economic Impacts Using Discrete-Event Simulation To Guide Health Policy Decisions, Odette Reifsnider
All Dissertations
This dissertation presents two applications of discrete-event simulation (DES) to represent clinical processes: (1) a model to quantify the risk of the maternal obese and diabetic intrauterine environment influence on progression to adult obesity and diabetes, and (2) a model to evaluate health and economic outcomes of different smoking cessation strategies. The first application considers the public health impact of the diabetic and obese intrauterine environment's effect on the prevalence of diabetes and obesity across subsequent generations. We first develop a preliminary DES model to investigate and characterize the epidemiology of diabetes during pregnancy and birth outcomes related to maternal …
Improving Quality Of Service In Ems Systems By Reducing Disparities Between Service Zones, Sunarin Chanta
Improving Quality Of Service In Ems Systems By Reducing Disparities Between Service Zones, Sunarin Chanta
All Dissertations
Emergency medical service (EMS) systems respond to emergency or urgent calls so as to provide immediate care, such as pre-hospital care and/or transportation, to hospitals. Care must be provided in a timely manner; in fact quality of service is usually directly associated with response time. To reduce the response time, the number and location of vehicles within the service area are important variables. However with limited capacity, increasing the number of vehicles is often an infeasible alternative. Therefore, a critical design goal is to decide at which facilities stations should be located in order to serve as much demand as …
Modeling And Optimization Of Stochastic Process Parameters In Complex Engineering Systems, Paul Goethals
Modeling And Optimization Of Stochastic Process Parameters In Complex Engineering Systems, Paul Goethals
All Dissertations
For quality engineering researchers and practitioners, a wide number of statistical tools and techniques are available for use in the manufacturing industry. The objective or goal in applying these tools has always been to improve or optimize a product or process in terms of efficiency, production cost, or product quality. While tremendous progress has been made in the design of quality optimization models, there remains a significant gap between existing research and the needs of the industrial community. Contemporary manufacturing processes are inherently more complex - they may involve multiple stages of production or require the assessment of multiple quality …
Pilot Weather Decision Making And The Influence Of Passenger Pressure, Jaclyn Baron
Pilot Weather Decision Making And The Influence Of Passenger Pressure, Jaclyn Baron
All Dissertations
The purpose of this study is to determine the effect of social pressure on general aviation (GA) pilots' weather decision making. Data have shown that GA accidents associated with visual flight rules (VFR) flight into instrument meteorological conditions (IMC) are more likely to result in fatalities than other types of GA accidents. This problem is compounded by the addition of passengers, who have been found to be present onboard during VFR into IMC accidents more frequently than in other types of GA accidents. The question is whether passengers influence a pilot's decision to continue flight into adverse weather. The extent …
A Decision Support System For Assessing Conveyance Options And Modeling Passenger Flow In Airport Terminals, Ping-Nan Chiang
A Decision Support System For Assessing Conveyance Options And Modeling Passenger Flow In Airport Terminals, Ping-Nan Chiang
All Dissertations
This dissertation focuses on the use of passenger conveyance systems and modeling passenger flow in airport terminals. The successfully designed airport concourse must perform at a level that meets the needs of its users - the passengers. In this research, we propose a database design methodology that allows key conveyance statistics to be analyzed within specific locations across the airport terminal. Using passenger conveyance observations collected at five North American airports, the database enables airport planners, operators and consultants to assess passenger behavior and conveyance device performance. Results from this section of the research were in direct support of the …
Micro Feature Enhanced Sinter Bonding Of Metal Injection Molded (Mim) Parts To A Solid Substrate, Thomas Martens
Micro Feature Enhanced Sinter Bonding Of Metal Injection Molded (Mim) Parts To A Solid Substrate, Thomas Martens
All Dissertations
In metal injection molding (MIM), fine metal powders are mixed with a binder and injected into molds, similar to plastic injection molding. After molding, the binder is removed from the part, and the compact is sintered to almost full density.
The obstacle to sinter bonding a MIM part to a conventional (solid) substrate lies in the sinter shrinkage of the MIM part, which can be up to 20%, meaning that the MIM part shrinks during sintering, while the conventional substrate maintains its dimensions. This behavior would typically inhibit bonding and/or cause cracking and deformation of the MIM part. It is …
Tight Polyhedral Representations Of Discrete Sets Using Projections, Simplices, And Base-2 Expansions, Stephen Henry
Tight Polyhedral Representations Of Discrete Sets Using Projections, Simplices, And Base-2 Expansions, Stephen Henry
All Dissertations
This research effort focuses on the acquisition of polyhedral outer-approximations to the convex hull of feasible solutions for mixed-integer linear and mixed-integer nonlinear programs. The goal is to produce desirable formulations that have superior size and/or relaxation strength. These two qualities often have great influence on the success of underlying solution strategies, and so it is with these qualities in mind that the work of this dissertation presents three distinct contributions.
The first studies a family of relatively unknown polytopes that enable the linearization of polynomial expressions involving two discrete variables. Projections of higher-dimensional convex hulls are employed to reduce …
In-Wheel Coupled Suspenison And Drive System For Attitude Control And Vehicle Propulsion, Robert Clippard
In-Wheel Coupled Suspenison And Drive System For Attitude Control And Vehicle Propulsion, Robert Clippard
All Dissertations
The automotive marketplace is a volatile and dynamic system driven by consumer desires, marketing, fuel prices, technology, and legislation. Recently many of these factors have culminated in a common effort to encourage hybrid and electric vehicle development. The technology for electric vehicles has finally found enough maturity to be implemented into consumer based vehicles from hybrid SUVs to high performance sports cars. This expansion in available propulsion systems and vehicle architectures has spurred research and development into new and novel approaches for propulsion as well as systems to provide increased ride comfort.
This work presents a dual electric motor drive …
A Meta-Analysis Of Human Factors Analysis And Classification System Causal Factors: Establishing Benchmarking Standards And Human Error Latent Failure Pathway Associations In Various Domains, Katherine Berry
All Dissertations
Many models of accident investigation have been created and have served as the basis for other tools and techniques. One of the most prominent techniques, Reason's Swiss Cheese Model (1990), is based on the idea of active and latent failures. Expanding on this idea, the Human Factors Analysis and Classification System (HFACS) was created with the idea to associate contributing factors and errors (Wiegmann & Shappell, 2003).
While HFACS has been frequently applied in the field of aviation in literature, other industry types are under-represented. Seventeen data sources encompassing various industry types were collected and included in this dissertation analysis. …
An Investigation Of Metaheuristics Using Path- Relinking On The Quadratic Assignment Problem, Thashika Rupasinghe
An Investigation Of Metaheuristics Using Path- Relinking On The Quadratic Assignment Problem, Thashika Rupasinghe
All Dissertations
The Quadratic Assignment Problem (QAP) is a widely researched, yet complex, combinatorial optimization problem that is applicable in modeling many real-world problems. Specifically, many optimization problems are formulated as QAPs. To resolve QAPs, the recent trends have been to use metaheuristics rather than exact or heuristic methods, and many researchers have found that the use of hybrid metaheuristics is actually more effective. A newly proposed hybrid metaheuristic is path relinking (PR), which is used to generate solutions by combining two or more reference solutions. In this dissertation, we investigated these diversification and intensification mechanisms using QAP. To satisfy the extensive …
Comprehensive Thermal Modeling Of Power Split Hybrid Power-Train And Electronics, Abdel Mayyas
Comprehensive Thermal Modeling Of Power Split Hybrid Power-Train And Electronics, Abdel Mayyas
All Dissertations
Hybrid electric vehicle (HEV) uses both internal combustion engine (ICE) with an electric system. The combination of the electric power train with the ICE is intended to achieve both better fuel economies than the conventional vehicles and better performance. Several types of HEV exist with different layouts. Recent HEVs' make use of regenerative braking, which converts the vehicles' kinetic energy into electric energy instead of wasting it as heat as conventional brakes do. A hybrid-electric is more fuel efficient than ICE and has less environmental impact.
The new HEV with its new Key Characteristics and Configurations (i.e. Mechanical complexity, Multiple …
Order Picking And Storage Using Stackable Pallets In A Warehouse, Ahmed Hassan Aly
Order Picking And Storage Using Stackable Pallets In A Warehouse, Ahmed Hassan Aly
All Dissertations
Quarter Billion dollars could be saved annually by double stacking pallets. A forklift storing 100 double stacked pallets saves 2.5 working hours versus single pallets. More than one billion pallets and cases handled between Wal-Mart distribution centers according to BEA White Paper (2006) [1], assume only 500 million were stackable pallets. This translates to 12.5 million working hours. If a forklift driver earns $20 per hour, then $250 million can be saved.
Moreover, handling double stacked pallets takes up to 46 % of total time to pick and store. This is a significant element that was ignored in literature. All …
Modeling Microbial And Nutrient Dynamics In Zero-Discharge Aquaculture Systems, Kendall Kirk
Modeling Microbial And Nutrient Dynamics In Zero-Discharge Aquaculture Systems, Kendall Kirk
All Dissertations
A finite element, finite difference model was developed to predict nutrient and microbial dynamics in recirculating aquaculture systems. Total ammonia nitrogen, nitrite, nitrate, chemical oxygen demand, and dissolved oxygen concentrations are predicted in addition to growth and decay of algae, Nitrosomonas, Nitrobacter, denitrifying heterotrophs, and aerobic heterotrophs. Inputs to the model include temperature, photosynthetically available radiation, feed application rate, pH, aeration/mixing energy, water exchange configuration, water exchange rate, tilapia biomass, and dissolved oxygen concentration. Up to 10 exchanged units may be included, user-definable as continuous stirred tank reactors or sequencing batch reactors. Demonstration of the model's utility was demonstrated through …
Assortment Planning For Multiple Quality Levels Using Locational Choice, Mark Mcelreath
Assortment Planning For Multiple Quality Levels Using Locational Choice, Mark Mcelreath
All Dissertations
Assortment planning is the process in which a retailer selects a product line to offer to customers and is a key determinant of a retailer's profit. We consider the assortment planning problem using a locational choice model for customer product selection and allow for both horizontal and vertical product differentiation. When the distribution of customer preference is unimodal, the optimal solutions for this problem are unknown. We propose two solution philosophies for generating product assortments. First, we introduce a metaheuristic representation for the problem and test the performance of three metaheuristic techniques. We suggest that a tabu search or genetic …
Estimation And Control Of Robotic Radiation-Based Processes, Fan Zeng
Estimation And Control Of Robotic Radiation-Based Processes, Fan Zeng
All Dissertations
This dissertation presents a closed-loop control and state estimation framework for a class of distributed-parameter processes employing a moving radiant actuator. These radiation-based processes have the potential to significantly reduce the energy consumption and environmental impact of traditional industrial processes. Successful implementation of these approaches in large-scale applications requires precise control systems. This dissertation provides a comprehensive framework for: 1) integration of trajectory generation and feedback control, 2) online distributed state and parameter estimation, and 3) optimal coordination of multiple manipulated variables, so as to achieve elaborate control of these radiation-based processes for improved process quality and energy efficiency.
The …
Simulation And Mathematical Modeling To Support Community-Wide Evacuation Decisions For Multiple Population Groups, Jun Duanmu
All Dissertations
Evacuating a large population from an at-risk area has been the subject of extensive research over the past few decades. In order to measure trip completion and total evacuation times accurately, most researchers have implemented some combination of simulation and optimization methods to provide vehicular flow and congestion data. While the general at-risk population comprises the majority of travelers on the road network, there are often specific groups to consider when assessing the ability to evacuate an entire population. In particular, healthcare facilities (e.g., hospitals) may require evacuation, and the trip times may become an important health issue for patients …
Principal Component Analysis Based Image Fusion Routine With Application To Stamping Split Detection, Yi Zhou
Principal Component Analysis Based Image Fusion Routine With Application To Stamping Split Detection, Yi Zhou
All Dissertations
This dissertation presents a novel thermal and visible image fusion system with application in online automotive stamping split detection. The thermal vision system scans temperature maps of high reflective steel panels to locate abnormal temperature readings indicative of high local wrinkling pressure that causes metal splitting. The visible vision system offsets the blurring effect of thermal vision system caused by heat diffusion across the surface through conduction and heat losses to the surroundings through convection. The fusion of thermal and visible images combines two separate physical channels and provides more informative result image than the original ones.
Principal Component Analysis …
Prioritizing Patients For Emergency Evacuation From A Healthcare Facility, Ashley Childers
Prioritizing Patients For Emergency Evacuation From A Healthcare Facility, Ashley Childers
All Dissertations
The success of a healthcare facility evacuation depends on communication and decision-making at all levels of the organization, from the coordinators at incident command to the clinical staff who actually carry out the evacuation. One key decision is the order in which each patient is chosen for evacuation. While the typical planning assumption is that all patients are to be evacuated, there may not always be adequate time or resources available to move all patients. In these cases, prioritizing or ordering patients for evacuation becomes an extremely difficult decision to make. These decisions should be based on the current state …
An Investigation On The Use And Flexibility Of Genetic Algorithms For Logistic Regression, Sara Yoder
An Investigation On The Use And Flexibility Of Genetic Algorithms For Logistic Regression, Sara Yoder
All Dissertations
Social scientists and other users of large data sets often desire a model to predict the probability that some condition exists, such as the probability that a person has diabetes or that a credit card transaction will be fraudulent. In general, this can be done by data mining techniques, which allow multiple records of data composed of numerous independent variables and one dependent variable to be examined in a statistical fashion to make a predictive model. One particular technique used is logistic regression. Logistic regression forms a predictive model based on a set of independent variables by assigning coefficients to …
Human Error In Mining: A Multivariable Analysis Of Mining Accidents/Incidents In Queensland, Australia And The United States Of America Using The Human Factors Analysis And Classification System Framework, Jessica Patterson
All Dissertations
Historically, mining has been viewed as an inherently high-risk industry. Nevertheless, the introduction of new technology and a heightened concern for safety has yielded marked reductions in accident and injury rates over the last several decades. In an effort to further reduce these rates, the human factors associated with incidents/accidents need to be addressed. A modified version of the Human Factors Classification and Analysis System (HFCAS-MI) was used to analyze lost time accidents and high-potential incidents from across Queensland, Australia and fatal accidents from the United States of America (USA) to identify human factor trends and system deficiencies within mining. …
A Scanpath Comparison Of The Salient Features Of Weather Among General Aviation Pilots Based On Training And Experience, Michael Sawyer
A Scanpath Comparison Of The Salient Features Of Weather Among General Aviation Pilots Based On Training And Experience, Michael Sawyer
All Dissertations
Over the last 20 years the number of annual accidents in general aviation has seen a steady decline. The annual number of fatal accidents, however, has remained relatively stable. Adverse weather is consistently cited as a leading cause of fatal accidents in general aviation; weather accidents have a fatality rate nearly four times that of other general aviation accidents. Reviews of accident data reveal that often these accidents occur when inexperienced pilots who are certified only for visual flight rules flight continue into adverse weather. The Situation Assessment Hypothesis suggests these accidents occur when pilots fail to accurately recognize weather …
Real-Time Vehicle Parameter Estimation And Adaptive Stability Control, John Limroth
Real-Time Vehicle Parameter Estimation And Adaptive Stability Control, John Limroth
All Dissertations
This dissertation presents a novel Electronic Stability Control (ESC) strategy that is capable of adapting to changing vehicle mass, tire condition and road surface conditions. The benefits of ESC are well understood with regard to assisting drivers to maintain vehicle control during extreme handling maneuvers or when extreme road conditions such as ice are encountered. However state of the art ESC strategies rely on known and invariable vehicle parameters such as vehicle mass, yaw moment of inertia and tire cornering stiffness coefficients. Such vehicle parameters may change over time, especially in the case of heavy trucks which encounter widely varying …
Development Of The Integrated Censored Robust-Tolerance Engineering Design Systems Via Improved Response Surface Modeling, Abdul-Baasit Shaibu
Development Of The Integrated Censored Robust-Tolerance Engineering Design Systems Via Improved Response Surface Modeling, Abdul-Baasit Shaibu
All Dissertations
In this dissertation, we intend to integrate censoring into robust-tolerance engineering using improved dual response surface modeling. This is perhaps the first attempt in the quality control literature. In the literature, response surface models have largely been restricted to second order (or quadratic) models and robust-tolerance designs have been restricted to situations involving complete observations. We intend to show that higher order response surface models can be more powerful in terms of prediction ability, and are therefore more reliable than the preferred quadratic models in the general context of robust design. We will also consider formulating robust and tolerance designs …
Effective Vr: Interplay Of Presence, Perception, Fidelity And Transfer Effects In The Development Of Inspection Training Simulators, Sajay Sadasivan
Effective Vr: Interplay Of Presence, Perception, Fidelity And Transfer Effects In The Development Of Inspection Training Simulators, Sajay Sadasivan
All Dissertations
Increased emphasis on aircraft inspection to ensure aviation safety has resulted in the need for a better trained workforce of aircraft maintenance personnel. Aircraft inspection is mostly visual in nature. Thus it has led to the development of computer simulators to train human inspectors performing the inspection task. However, the lack of immersion and interaction in such simulators has led to limited effectiveness and adoption. Using advances in graphics and virtual reality technology, there is an increase the sense of involvement in using these simulators. Though technology is available to provide higher levels of immersion, it is expensive. It is …