Operations Research, Systems Engineering and Industrial Engineering Commons^™

Location And Capacity Modeling Of Network Interchanges, Aldo D. Fabregas

USF Tampa Graduate Theses and Dissertations

Network design decisions, especially those pertaining to urban infrastructure, are made by a central authority or network leader, and taking into consideration the network users or followers. These network decision problems are formulated as non-linear bi-level programming problems. In this work, a continuous network design problem (CNDP) and discrete network design problem (DNDP) bi-level optimization programs are proposed and solved in the context of transportation planning. The solution strategy involved reformulation and linearization as a single-level program by introducing the optimality conditions of the lower level problem into the upper level problem. For the CNDP, an alternative linearization algorithm (modified …

The Impact Of Organizations' Collaboration Strategies And Alliance Network Positions On Invention Performance, Fethullah Caliskan

USF Tampa Graduate Theses and Dissertations

This research investigates the impact of organizations' collaboration strategies and network positional variables on invention performance. Organizations, particularly those pursuing a differentiation strategy, are motivated to introduce novel products and services in order to remain competitive. Thus, two questions of interest to such organizations regarding the network dynamics of the invention process are: 1) What kind of strategies allow them to attain superior invention results? 2) What is the most advantageous structural positioning in a collaborative network of innovators? Three independent studies attempt to find answers to these questions by using three complementary study approaches.

In the first study, in …

Predicting The Clinical Outcome In Patients With Traumatic Brain Injury Using Clinical Pathway Scores, Jennifer Lorena Mendoza Alonzo

USF Tampa Graduate Theses and Dissertations

The Polytrauma/TBI Rehabilitation Center (PRC) of the Veterans Affairs Hospital (VAH) treats patients with Traumatic Brain Injury (TBI). These patients have major motor and cognitive disabilities. Most of the patients stay in the hospital for many months without major improvements. This suggests that patients, family and the VAH could benefit if healthcare provider had a way to better assess or "predict" patients' progression. The individual progress of patients over time is assessed using a pre-defined multi-component performance measure Functional Independence Measures (FIM) at admission and discharge, and a semi-quantitative documentation parameter Clinical Pathway (CP) at weekly intervals. This work uses …

Novel Models And Algorithms For Uncertainty Management In Power Systems, Long Zhao

USF Tampa Graduate Theses and Dissertations

This dissertation is a collection of previously-published manuscript and conference papers. In this dissertation, we will deal with a stochastic unit commitment problem with cooling systems for gas generators, a robust unit commitment problem with demand response and uncertain wind generation, and a power grid vulnerability analysis with transmission line switching. The latter two problems correspond to our theoretical contributions in two-stage robust optimization, i.e., how to efficiently solve a two-stage robust optimization, and how to deal with mixed-integer recourse in robust optimization. Due to copyright issue, this dissertation does not include any methodology papers written by the author during …

A Methodology For Scheduling Operating Rooms Under Uncertainty, Marbelly Paola Davila

USF Tampa Graduate Theses and Dissertations

An operating room (OR) is considered to be one of the most costly functional areas within hospitals as well as its major profit center. It is known that managing an OR department is a challenging task, which requires the integration of many actors (e.g., patients, surgeons, nurses, technicians) who may have conflicting interests and priorities.

Considering these aspects, this dissertation focuses on developing a simulation based methodology for scheduling operating rooms under uncertainty, which reflects the complexity, uncertainty and variability associated with surgery.

We split the process of scheduling ORs under uncertainty into two main components. First, we designed a …

Supply Chain Optimization Of Blood Products, Serkan Gunpinar

USF Tampa Graduate Theses and Dissertations

Major challenges in the management of blood supply chain are related to the shortage and wastage of the blood products. Given the perishability characteristics of blood which can be stored up to a limited number of days, if hospitals and blood centers keep an excessive number of blood units on inventory, wastages may occur. On the other hand, if sufficient number of blood units are not stored on inventory, shortages of this resource may cause the cancellations of important activities and increase the fatality rates at hospitals. Three mathematical models have been developed with the goal to improve the efficiency …

Classification Models In Clinical Decision Making, Eleazar Gil-Herrera

USF Tampa Graduate Theses and Dissertations

In this dissertation, we present a collection of manuscripts describing the development of prognostic models designed to assist clinical decision making. This work is motivated by limitations of commonly used techniques to produce accessible prognostic models with easily interpretable and clinically credible results. Such limitations hinder prognostic model widespread utilization in medical practice.

Our methodology is based on Rough Set Theory (RST) as a mathematical tool for clinical data anal- ysis. We focus on developing rule-based prognostic models for end-of life care decision making in an effort to improve the hospice referral process. The development of the prognostic models is …

Extensions Of Multistage Stochastic Optimization With Applications In Energy And Healthcare, Ludwig Charlemagne Kuznia

USF Tampa Graduate Theses and Dissertations

This dissertation focuses on extending solution methods in the area of stochastic optimization. Attention is focused to three specific problems in the field. First, a solution method for mixed integer programs subject to chance constraints is discussed. This class of problems serves as an effective modeling framework for a wide variety of applied problems. Unfortunately, chance constrained mixed integer programs tend to be very challenging to solve. Thus, the aim of this work is to address some of these challenges by exploiting the structure of the deterministic reformulation for the problem. Second, a stochastic program for integrating renewable energy sources …

Engineering Of A Knowledge Management System For Relational Medical Diagnosis, Maria Carolina Herrera-Hernandez

USF Tampa Graduate Theses and Dissertations

The increasingly high costs of health care in the U.S. have led the general public to search for different medical approaches. Since the 1990's, the use of Complementary and Alternative Medicine (CAM) has radically increased in the U.S. due to its approach to treat physical, mental, and emotional causes of illness. In 2009, the National Health Statistics reported the impact of CAM in the U.S. health care economy, with population expenditures of $14.8 billion out-of-pocket on natural Medicine and $12.4 billion out-of-pocket on visits to CAM providers as a complement to Western Medicine care.

CAM interconnects human functions to reach …

Modeling And Surveillance Of Pandemic Influenza Outbreaks, Diana Prieto

USF Tampa Graduate Theses and Dissertations

Pandemic outbreaks are unpredictable as to their virus strain, transmissibility, and impact on our quality of life. Hence, the decision support models for mitigation of pandemic outbreaks must be user-friendly and operational, and also incorporate valid estimates of disease transmissibility and severity. This dissertation research is aimed at 1) reviewing the existing pandemic simulation models to identify their implementation gaps with regard to usability and operability, and suggesting research remedies, 2) increasing operability of simulation models by calibrating them via an epidemiological model that estimates infection probabilities using viral shedding profiles of concurrent pandemic and seasonal influenza, and 3) developing …

Cap-And-Trade Modeling And Analysis For Electric Power Generation Systems, Patricio Rocha

USF Tampa Graduate Theses and Dissertations

Cap-and-trade is the most discussed CO₂ emissions control scheme in the U.S. It is a market-based mechanism that has been used previously to successfully reduce the levels of SO₂ and NO_x emitted by power generators. Since electricity generators are responsible for about 40% of the CO₂ emissions in the U.S., the implementation of CO₂ cap-and-trade will have a significant impact on electric power generation systems. In particular, cap-and-trade will influence the investment decisions made by power generators. These decisions in turn, will affect electricity prices and demand. If the allowances (or emission permits) created by …

The Impact Of Supply Chain And Network Structure On The Environmental Performance Of Sustainability-Focused Companies, Ozan Ozcan

USF Tampa Graduate Theses and Dissertations

The goal of this dissertation was to contribute to our understanding of the relationship between supply chain structure and the pursuit of a sustainability-driven corporate strategy. The literature indicates that in order to pursue a sustainability-focused strategy, an increased level of integration across the supply chain is required. However, there are also industry-level dynamics that impact observed levels of vertical integration. That is, some industries are naturally more integrated than others based on the maturity level of the industry. Thus, some firms may experience opposing forces regarding their sourcing strategies once they choose to pursue a sustainability-focused strategy.

To explore …

Apparent Total Evaporative Resistance Values From Human Trials Over A Range Of Metabolic And Heat Stress Levels, Matthew David Dooris

USF Tampa Graduate Theses and Dissertations

Failure to maintain thermal equilibrium can cause uncontrollable increases in body core temperature beyond critical upper limits. In selecting clothing, consideration must be given to the heat transfer properties of clothing that may restrict the cooling capacity of the human body under heat stress conditions, most importantly, apparent total evaporative resistance (R_e,T,_a). This study calculated and compared R_e,T,_a for five clothing ensembles under varying heat stress conditions, including three relative humidity (RH) levels and three stages of heat stress to determine if R_e,T,_a values varied or remained the same with …

Decision Aid Models For Resource Sharing Strategies During Global Influenza Pandemics, Alfredo Santana Reynoso

USF Tampa Graduate Theses and Dissertations

Pandemic influenza outbreaks have historically entailed significant societal and economic disruptions. Today, our quality of life is threatened by our inadequate preparedness for the imminent pandemic. The key challenges we are facing stem from a significant uncertainty in virus epidemiology, limited response resources, inadequate international collaboration, and the lack of appropriate science-based decision support tools. The existing literature falls short of comprehensive models for global pandemic spread and mitigation which incorporate the heterogeneity of the world regions and realistic travel networks. In addition, there exist virtually no studies which quantify the impact of resource sharing strategies among multiple countries. This …

Identification Of Patient Recovery Patterns After Cardiovascular Surgery Based On Laboratory Tests Results, Alcides Ricardo Santander Mercado

USF Tampa Graduate Theses and Dissertations

In this dissertation is proposed a methodology to identify patient's recovery patterns after cardiovascular surgery based on laboratory tests results. The main purpose is to enhance the understanding of the manifestations of postsurgical complications in patients who underwent cardiovascular surgery. The analysis of patients' recovery process is based on the relationship between plasma calcium, ionized calcium and platelet count over time.

Laboratory results from the James A. Haley Veterans' Hospital databases, related to patients admitted to the Surgical Intensive Care Unit (SICU) after cardiac surgery (coronary artery bypass, aortic value replacement and mitral valve replacement), are used. These databases contain …

Decision Support Models For Design Of Fortified Distribution Networks, Qingwei Li

USF Tampa Graduate Theses and Dissertations

Lean distribution networks have been facing an increased exposure to the risk of unpredicted disruptions causing significant economic forfeitures. At the same time, the existing literature contains very few studies that examine the impact of fortification of facilities for improving network reliability. This dissertation presents three related classes of models that support the design of reliable distribution networks. The models extend the uncapacitated P-median and fixed-charge location models by considering heterogeneous facility failure probabilities, supplier backups, and facility fortification within a finite budget. The first class of models considers binary fortification via linear fortification functions. The second class of models …

The Impact Of Pharmacy Work Design On Pharmacist Productivity, Nicholas Allen Coblio

USF Tampa Graduate Theses and Dissertations

Healthcare costs in the United States continue to grow at an alarming rate. Concerning the cost of medications, there are a number of factors that drive these costs. While personnel costs are not the largest of these, they do contribute a significant portion. The cost of the cognitive component of order processing by pharmacists can range from three dollars to over six dollars per prescription depending on the production throughput of the pharmacist.

Studies at the organization which was the focus of the research, as well as reports in the literature, indicated that work disruption and other environmental factors could …

Analytical Methods To Support Risk Identification And Analysis In Healthcare Systems, Laila Nadime Cure Vellojin

USF Tampa Graduate Theses and Dissertations

Healthcare systems require continuous monitoring of risk to prevent adverse events. Risk analysis is a time consuming activity that depends on the background of analysts and available data. Patient safety data is often incomplete and biased. This research proposes systematic approaches to monitor risk in healthcare using available patient safety data. The methodologies combine traditional healthcare risk analysis methods with safety theory concepts, in an innovative manner, to allocate available evidence to potential risk sources throughout the system. We propose the use of data mining to analyze near-miss reports and guide the identification of risk sources. In addition, we propose …

A Framework For Determining The Reliability Of Nanoscale Metallic Oxide Semiconductor (Mos) Devices, Wilkistar Otieno

USF Tampa Graduate Theses and Dissertations

An increase in worldwide investments during the past several decades has pro-pelled scienti c breakthroughs in nanoscience and technology research to new and exciting levels. To ensure that these discoveries lead to commercially viable prod-ucts, it is important to address some of the fundamental engineering and scientific challenges related to nanodevices. Due to the centrality of reliability to product integrity, nanoreliability requires critical analysis and understanding to ensure long-term sustainability of nanodevices and systems. In this study, we construct a relia-bility framework for nanoscale dielectric lms used in Metallic Oxide Semiconductor (MOS) devices. The successful fabrication and incorporation of metallic …

Design Of A New Suturing And Knot Tying Device For Laparoscopic Surgery, Sinan Onal

USF Tampa Graduate Theses and Dissertations

Minimally invasive or laparoscopic surgery has completely changed the focus of surgery becoming an alternative to various types of open surgery. Minimally invasive surgery avoids invasive open surgery as the operation is performed through one or more small incisions in the abdomen and using a small camera called laparoscope. Through these incisions, surgeons insert specialized surgical instruments to perform the operation resulting in less postoperative pain, shorter hospital stay, and faster recovery. However, the main problems during minimally-invasive surgery are the limited space for operating instruments and the reduced visibility and range of motion inside the patient’s body. During minimally-invasive …

Heat Stress Evaluation Of Protective Clothing Ensembles, Amanda Lee Pease

USF Tampa Graduate Theses and Dissertations

Clothing directly affects the level of heat stress exposure. Useful measures to express the thermal characteristics are WBGT (wet bulb globe temperature) clothing adjustment factor (CAF) or apparent total evaporative resistance (R_e,T,_a). The CAF is assigned through laboratory wear trials following a heat stress protocol in which the air temperature and humidity are progressively increased until the participant clearly loses the ability to maintain thermal equilibrium. The critical condition is the point of thermal transition and from these conditions both the CAF and Re,T,a are computed. The first objective of this study is to compare the …

Automatic Generation Of Plc Code Based On Net Condition Event Systems, Natalia Sandberg

USF Tampa Graduate Theses and Dissertations

An important consideration in discrete event dynamic systems control theory is the selection of a suitable modeling formalism that can capture the complex characteristics of the system and the capability to automatically synthesize a controller based on the system model. Net condition event systems are well suited for modeling complex discrete event dynamic systems owing to their input and output structure, which effectively captures the behavior of the physical devices to be monitored and/or controlled. To date, net condition event systems control models have not been extensively applied to highly automated manufacturing systems and there are few guidelines on how …

Physical-Statistical Modeling And Optimization Of Cardiovascular Systems, Dongping Du

USF Tampa Graduate Theses and Dissertations

Heart disease remains the No.1 leading cause of death in U.S. and in the world. To improve cardiac care services, there is an urgent need of developing early diagnosis of heart diseases and optimal intervention strategies. As such, it calls upon a better understanding of the pathology of heart diseases.

Computer simulation and modeling have been widely applied to overcome many practical and ethical limitations in in-vivo, ex-vivo, and whole-animal experiments. Computer experiments provide physiologists and cardiologists an indispensable tool to characterize, model and analyze cardiac function both in healthy and in diseased heart. Most importantly, simulation modeling empowers the …