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Full-Text Articles in Nanoscience and Nanotechnology
Fabrication Of Magnetic Two-Dimensional And Three-Dimensional Microstructures For Microfluidics And Microrobotics Applications, Hui Li
Theses and Dissertations--Mechanical Engineering
Micro-electro-mechanical systems (MEMS) technology has had an increasing impact on industry and our society. A wide range of MEMS devices are used in every aspects of our life, from microaccelerators and microgyroscopes to microscale drug-delivery systems. The increasing complexity of microsystems demands diverse microfabrication methods and actuation strategies to realize. Currently, it is challenging for existing microfabrication methods—particularly 3D microfabrication methods—to integrate multiple materials into the same component. This is a particular challenge for some applications, such as microrobotics and microfluidics, where integration of magnetically-responsive materials would be beneficial, because it enables contact-free actuation. In addition, most existing microfabrication methods …
An Implantable Device For Manipulation Of The In Vivo Tumor Microenvironment, James K. Williams
An Implantable Device For Manipulation Of The In Vivo Tumor Microenvironment, James K. Williams
Legacy Theses & Dissertations (2009 - 2024)
In the past decade, it has become increasingly recognized that interactions between cancer cells and the tumor microenvironment (TME) regulate metastasis. One such interaction is the paracrine loop between macrophages and cancer cells which drives metastatic invasion in mammary tumors. Tumor associated macrophages release epidermal growth factor (EGF), a chemoattractant which induces the migration of cancer cells toward the blood vessels. The cancer cells reciprocate by releasing a macrophage chemoattractant, colony-stimulating factor 1 (CSF-1), resulting in the co-migration of both cell types and subsequent intravasation. In this work, a new technology has been developed for studying the mechanisms by which …
Development Of A Nitrogen Incorporated Ultrananocrystalline Diamond Film Based Field Emitter Array For A Flat Panel X-Ray Source, Chrystian Mauricio Posada
Development Of A Nitrogen Incorporated Ultrananocrystalline Diamond Film Based Field Emitter Array For A Flat Panel X-Ray Source, Chrystian Mauricio Posada
Doctoral Dissertations
"As an alternative to conventional X-ray sources, a flat panel transmission X-ray source is being developed. A field emitter array (FEA) prototype to be incorporated as cold cathode in this flat panel X-ray source was fabricated for this work. Using the Particle-in-Cell code OOPIC Pro, an initial FEA was designed through simulations. Based on the simulation results, a FEA prototype was fabricated using conventional microfabrication techniques. Planar nitrogen-incorporated ultrananocrystalline diamond (N-UNCD) films were used as field emitters. This N-UNCD based FEA prototype was composed of 9 pixels distributed in a 3x3 array, with a pixel size of 225x225 µm, and …