Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Manufacturing
Therapeutic Ultrasound Angioplasty: The Risk Of Arterial Perforation. An In Vitro Study, Mark Wylie, Garrett Mcguinness, Graham Gavin
Therapeutic Ultrasound Angioplasty: The Risk Of Arterial Perforation. An In Vitro Study, Mark Wylie, Garrett Mcguinness, Graham Gavin
Conference Papers
The use of therapeutic ultrasound delivered via small diameter wire waveguides may represent an emerging minimally invasive approach in the treatment of chronic total occlusions (CTOs), calcified and fibrous plaques. The distal-tip mechanical vibrations (typically 0-210 μm peak-to-peak) have been reported to debulk rigid calcified and fibrous tissues while healthy elastic arterial tissue remains largely unaffected. The risk of arterial (healthy tissue) perforation with energized waveguides is not fully understood. An ultrasonic apparatus capable of delivering a range of wire waveguide distal-tip displacements, up to 80 μm peak-to-peak (p-p), at an operational frequency of 22.5 KHz (+/- 6%) has been …
Ultrasonic Angioplasty: Assessing The Risk Of Arterial Perforation, Mark Wylie, Garrett Mcguinness, Graham Gavin
Ultrasonic Angioplasty: Assessing The Risk Of Arterial Perforation, Mark Wylie, Garrett Mcguinness, Graham Gavin
Conference Papers
Atherosclerosis is a cardiovascular disease that effects large and medium muscular arteries (such as coronary and iliac) and also large elastic arteries (such as aorta) [1]. It causes thickening of the arterial wall and over time can result in a completely blocked artery or chronic total occlusion (CTO). While the majority of atherosclerotic lesions can be attempted by typical Percutaneous Transluminal Coronary Angioplasty (PTCA) such as balloon and stent implantation, calcified CTOs are often problematic as they do not lend themselves to be accessed by the guidewire which is required to implant the balloon and stent. Excessive guidewire pushing force …