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Full-Text Articles in Applied Mechanics

Ternary Flow Simulation Based On The Conservative Phase Field Lattice Boltzmann Method, Chunheng Zhao Jan 2022

Ternary Flow Simulation Based On The Conservative Phase Field Lattice Boltzmann Method, Chunheng Zhao

Dissertations and Theses

In this thesis, we numerically investigated multi-phase fluid dynamics (2 and 3-phase flow) by solving the Navier-Stokes equations coupled with the conservative phase field (CPF) equations using the Lattice Boltzmann method (LBM). To effectively simulate the large-scale multi-phase physics, we developed an open-source software, IMEXLBM, which can be easily parallelized on both CPUs and GPUs without significant modifications to the code. We first validated various parts of this software and then used this method to study the interaction of rising bubbles with a static oil droplet as well as the engulfment of the water droplet on solids coated with a …


Fluid Agitation Studies For Drug Product Containers Using Computational Fluid Dynamics, Matthew Hiroki Ichinose Dec 2018

Fluid Agitation Studies For Drug Product Containers Using Computational Fluid Dynamics, Matthew Hiroki Ichinose

Master's Theses

At Amgen, the Automated Vision Inspection (AVI) systems capture the movement of unwanted particles in Amgen's drug product containers. For quality inspection, the AVI system must detect these undesired particles using a high speed spin-stop agitation process. To better understand the fluid movements to swirl the particles away from the walls, Computational Fluid Dynamics (CFD) is used to analyze the nature of the two phase flow of air and a liquid solution.

Several 2-D and 3-D models were developed using Fluent to create simulations of Amgen's drug product containers for a 1 mL syringe, 2.25 mL syringe, and a 5 …