Applied Mechanics Commons^™

Understanding The Effects Of Blast Wave On The Intracranial Pressure And Traumatic Brain Injury In Rodents And Humans Using Experimental Shock Tube And Numerical Simulations, Aravind Sundaramurthy

Department of Engineering Mechanics: Dissertations, Theses, and Student Research

Blast induced neurotrauma (BINT) has been designated as the “signature injury” to warfighters in the recent military conflicts. In the past decade, conflicts in Iraq (operation Iraqi freedom) and Afghanistan (operation enduring freedom) as well as the increasing burden of the terrorism around the world resulted in an increased number of cases with blast Traumatic Brain Injury (bTBI). Recently, a lot of research has been done to study the neurological and neurochemical degenerations resulting from BINT using animal models especially rat models. However, it is not clear how and whether the biological outcomes from animal models can be translated to …

Mechanics Of Blast Loading On Post-Mortem Human And Surrogate Heads In The Study Of Traumatic Brain Injury (Tbi) Using Experimental And Computational Approaches, Shailesh Govind Ganpule

Department of Engineering Mechanics: Dissertations, Theses, and Student Research

Blast induced neurotrauma (BINT) has been designated as the “signature injury” to warfighters in the recent military conflicts. The occurrence of traumatic brain injury (TBI) in blasts is controversial in the medical and scientific communities because the manifesting symptoms occur without visible injuries. Whether the primary blast waves alone can cause mechanical insult that is comparable to existing traumatic brain injury thresholds is still an open question, and this work is aimed to address this issue.

In the first part of this dissertation, mechanics of primary blast loading on Realistic Explosive Dummy (RED) head with and without helmets is studied …