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Full-Text Articles in Electrical and Electronics
Development Of A Portable Cmos Time-Domain Fluorescence Lifetime Imager, Hongtao Wang
Development Of A Portable Cmos Time-Domain Fluorescence Lifetime Imager, Hongtao Wang
Doctoral Dissertations
Modern laboratory equipments to measure the excited-state lifetime of fluorophores usually include an expensive picosecond pulsed-laser excitation source, a fragile photomultiplier tube, and a large instrument body for optics. A portable and robust device to make fluorescence lifetime measurement in nanosecond scale is of great attraction for chemists and biologists. This dissertation reports the development of a portable LED time-domain fluorimeter from an all-solid-state discrete-component prototype to its advanced CMOS integrated circuit implementation. The motivation of the research is to develop a multiplexed fluorimeter for point-of-care diagnosis. Instruments developed by this novel method have higher fill factor, are more portable, …
Design And Implementation Of An Integrated Biosensor Platform For Lab-On-A-Chip Diabetic Care Systems, Khandaker Abdullah Al Mamun
Design And Implementation Of An Integrated Biosensor Platform For Lab-On-A-Chip Diabetic Care Systems, Khandaker Abdullah Al Mamun
Doctoral Dissertations
Recent advances in semiconductor processing and microfabrication techniques allow the implementation of complex microstructures in a single platform or lab on chip. These devices require fewer samples, allow lightweight implementation, and offer high sensitivities. However, the use of these microstructures place stringent performance constraints on sensor readout architecture. In glucose sensing for diabetic patients, portable handheld devices are common, and have demonstrated significant performance improvement over the last decade. Fluctuations in glucose levels with patient physiological conditions are highly unpredictable and glucose monitors often require complex control algorithms along with dynamic physiological data. Recent research has focused on long term …