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Old Dominion University

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2017

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Articles 1 - 17 of 17

Full-Text Articles in Electrical and Computer Engineering

Activation Of The Phospholipid Scramblase Tmem16f By Nanosecond Pulsed Electric Field (Nspef) Facilitates Its Diverse Cytophysiological Effects, Claudia Muratori, Andrei G. Pakhomov, Elena Gianulis, Jade Meads, Maura Casciola, Peter A. Mollica, Olga N. Pakhomova Oct 2017

Activation Of The Phospholipid Scramblase Tmem16f By Nanosecond Pulsed Electric Field (Nspef) Facilitates Its Diverse Cytophysiological Effects, Claudia Muratori, Andrei G. Pakhomov, Elena Gianulis, Jade Meads, Maura Casciola, Peter A. Mollica, Olga N. Pakhomova

Bioelectrics Publications

Nanosecond pulsed electric fields (nsPEF) are emerging as a novel modality for cell stimulation and tissue ablation. However, the downstream protein effectors responsible for nsPEF bioeffects remain to be established. Here we demonstrate that nsPEF activate TMEM16F (or Anoctamin 6), a protein functioning as a Ca2+-dependent phospholipid scramblase and Ca2+-activated chloride channel. Using confocal microscopy and patch clamp recordings, we investigated the relevance of TMEM16F activation for several bioeffects triggered by nsPEF, including phosphatidylserine (PS) externalization, nanopore-conducted currents, membrane blebbing, and cell death. In HEK 293 cells treated with a single 300-ns pulse of 25.5 kV/cm, …


Defects In Skeletal Muscle Subsarcolmmal Mitochondria In A Non-Obese Model Of Type 2 Diabetes Mellitus, Nicola Lai, China Kummitha, Charles Hoppel Aug 2017

Defects In Skeletal Muscle Subsarcolmmal Mitochondria In A Non-Obese Model Of Type 2 Diabetes Mellitus, Nicola Lai, China Kummitha, Charles Hoppel

Electrical & Computer Engineering Faculty Publications

Skeletal muscle resistance to insulin is related to accumulation of lipid-derived products, but it is not clear whether this accumulation is caused by skeletal muscle mitochondrial dysfunction. Diabetes and obesity are reported to have a selective effect on the function of subsarcolemmal and interfibrillar mitochondria in insulin-resistant skeletal muscle. The current study investigated the role of the subpopulations of mitochondria in the pathogenesis of insulin resistance in the absence of obesity. A non-obese spontaneous rat model of type 2 diabetes mellitus, (Goto-Kakizaki), was used to evaluate function and biochemical properties in both populations of skeletal muscle mitochondria. In subsarcolemmal mitochondria, …


Nanostructure Evolution Of Magnetron Sputtered Hydrogenated Silicon Thin Films, Dipendra Adhikari, Maxwell M. Junda, Sylvain X. Marsillac, Robert W. Collins, Nikolas J. Podraza Aug 2017

Nanostructure Evolution Of Magnetron Sputtered Hydrogenated Silicon Thin Films, Dipendra Adhikari, Maxwell M. Junda, Sylvain X. Marsillac, Robert W. Collins, Nikolas J. Podraza

Electrical & Computer Engineering Faculty Publications

Hydrogenated silicon (Si:H) thin films have been prepared by radio frequency (RF) magnetron sputtering. The effect of hydrogen gas concentration during sputtering on the resultant film structural and optical properties has been investigated by real time spectroscopic ellipsometry (RTSE) and grazing incidence x-ray diffraction (GIXRD). The analysis of in-situ RTSE data collected during sputter deposition tracks the evolution of surface roughness and film bulk layer thickness with time. Growth evolution diagrams depicting amorphous, nanocrystalline and mixed-phase regions for low and high deposition rate Si:H are constructed and the effects of process parameter (hydrogen gas concentration, total pressure and RF power) …


Perspective: The Physics, Diagnostics, And Applications Of Atmospheric Pressure Low Temperature Plasma Sources Used In Plasma Medicine, M. Laroussi Jul 2017

Perspective: The Physics, Diagnostics, And Applications Of Atmospheric Pressure Low Temperature Plasma Sources Used In Plasma Medicine, M. Laroussi

Electrical & Computer Engineering Faculty Publications

Low temperature plasmas have been used in various plasma processing applications for several decades. But it is only in the last thirty years or so that sources generating such plasmas at atmospheric pressure in reliable and stable ways have become more prevalent. First, in the late 1980s, the dielectric barrier discharge was used to generate relatively large volume diffuse plasmas at atmospheric pressure. Then, in the early 2000s, plasma jets that can launch cold plasma plumes in ambient air were developed. Extensive experimental and modeling work was carried out on both methods and much of the physics governing such sources …


Aluminum Multicharged Ion Generation From Femtosecond Laser Plasma, Md. Haider A. Shaim, Frederick Guy Wilson, Hani E. Elsayed-Ali May 2017

Aluminum Multicharged Ion Generation From Femtosecond Laser Plasma, Md. Haider A. Shaim, Frederick Guy Wilson, Hani E. Elsayed-Ali

Electrical & Computer Engineering Faculty Publications

Aluminum multicharged ion generation from femtosecond laser ablation is studied. A Ti:sapphire laser (wavelength 800 nm, pulse width ∼100 fs, and maximum laser fluence of 7.6 J/cm2) is used. Ion yield and energy distribution of each charge state are measured. A linear relationship between the ion charge state and the equivalent acceleration energy of the individual ion species is observed and is attributed to the presence of an electric field within the plasma-vacuum boundary that accelerates the ions. The ion energy distribution follows a shifted Coulomb-Boltzmann distribution. For Al1+ and Al2+, the ion energy distributions …


Impact Of Rram Read Fluctuations On The Program-Verify Approach, David M. Nminibapiel, Dmitry Veksler, J.-H. Kim, Pragya R. Shrestha, Jason P. Campbell, Jason T. Ryan, Helmut Baumgart, Kin P. Cheung May 2017

Impact Of Rram Read Fluctuations On The Program-Verify Approach, David M. Nminibapiel, Dmitry Veksler, J.-H. Kim, Pragya R. Shrestha, Jason P. Campbell, Jason T. Ryan, Helmut Baumgart, Kin P. Cheung

Electrical & Computer Engineering Faculty Publications

The stochastic nature of the conductive filaments in oxide-based resistive memory (RRAM) represents a sizeable impediment to commercialization. As such, program-verify methodologies are highly alluring. However, it was recently shown that program-verify methods are unworkable due to strong resistance state relaxation after SET/RESET programming. In this paper, we demonstrate that resistance state relaxation is not the main culprit. Instead, it is fluctuation-induced false-reading (triggering) that defeats the program-verify method, producing a large distribution tail immediately after programming. The fluctuation impact on the verify mechanism has serious implications on the overall write/erase speed of RRAM.


Power Budgets For Cubesat Radios To Support Ground Communications And Inter-Satellite Links, Otilia Popescu Jan 2017

Power Budgets For Cubesat Radios To Support Ground Communications And Inter-Satellite Links, Otilia Popescu

Engineering Technology Faculty Publications

CubeSats are a class of pico-satellites that have emerged over the past decade as a cost-effective alternative to the traditional large satellites to provide space experimentation capabilities to universities and other types of small enterprises, which otherwise would be unable to carry them out due to cost constraints. An important consideration when planning CubeSat missions is the power budget required by the radio communication subsystem, which enables a CubeSat to exchange information with ground stations and/or other CubeSats in orbit. The power that a CubeSat can dedicate to the communication subsystem is limited by the hard constraints on the total …


Sensitivity Analysis Method To Address User Disparities In The Analytic Hierarchy Process, Marie Ivanco, Gene Hou, Jennifer Michaeli Jan 2017

Sensitivity Analysis Method To Address User Disparities In The Analytic Hierarchy Process, Marie Ivanco, Gene Hou, Jennifer Michaeli

Mechanical & Aerospace Engineering Faculty Publications

Decision makers often face complex problems, which can seldom be addressed well without the use of structured analytical models. Mathematical models have been developed to streamline and facilitate decision making activities, and among these, the Analytic Hierarchy Process (AHP) constitutes one of the most utilized multi-criteria decision analysis methods. While AHP has been thoroughly researched and applied, the method still shows limitations in terms of addressing user profile disparities. A novel sensitivity analysis method based on local partial derivatives is presented here to address these limitations. This new methodology informs AHP users of which pairwise comparisons most impact the derived …


Secrecy Rates And Optimal Power Allocation For Full-Duplex Decode-And-Forward Relay Wire-Tap Channels, Lubna Elsaid, Leonardo Jimenez-Rodriguez, Nghi H. Tran, Sachin Shetty, Shivakumar Sastry Jan 2017

Secrecy Rates And Optimal Power Allocation For Full-Duplex Decode-And-Forward Relay Wire-Tap Channels, Lubna Elsaid, Leonardo Jimenez-Rodriguez, Nghi H. Tran, Sachin Shetty, Shivakumar Sastry

Computational Modeling & Simulation Engineering Faculty Publications

This paper investigates the secrecy rates and optimal power allocation schemes for a decode-and-forward wiretap relay channel where the transmission from a source to a destination is aided by a relay operating in a full-duplex (FD) mode under practical residual self-interference. By first considering static channels, we address the non-convex optimal power allocation problems between the source and relay nodes under individual and joint power constraints to establish closed-form solutions. An asymptotic analysis is then given to provide important insights on the derived power allocation solutions. Specifically, by using the method of dominant balance, it is demonstrated that full power …


Semantic Inference On Clinical Documents: Combining Machine Learning Algorithms With An Inference Engine For Effective Clinical Diagnosis And Treatment, Shuo Yang, Ran Wei, Jingzhi Guo, Lida Xu Jan 2017

Semantic Inference On Clinical Documents: Combining Machine Learning Algorithms With An Inference Engine For Effective Clinical Diagnosis And Treatment, Shuo Yang, Ran Wei, Jingzhi Guo, Lida Xu

Information Technology & Decision Sciences Faculty Publications

Clinical practice calls for reliable diagnosis and optimized treatment. However, human errors in health care remain a severe issue even in industrialized countries. The application of clinical decision support systems (CDSS) casts light on this problem. However, given the great improvement in CDSS over the past several years, challenges to their wide-scale application are still present, including: 1) decision making of CDSS is complicated by the complexity of the data regarding human physiology and pathology, which could render the whole process more time-consuming by loading big data related to patients; and 2) information incompatibility among different health information systems (HIS) …


Dynamic Transition Of Vortices Into Phase Slips And Generation Of Vortex-Antivortex Pairs In Thin Film Josephson Junctions Under Dc And Ac Currents, Ahmad Sheikhzada, Alex Gurevich Jan 2017

Dynamic Transition Of Vortices Into Phase Slips And Generation Of Vortex-Antivortex Pairs In Thin Film Josephson Junctions Under Dc And Ac Currents, Ahmad Sheikhzada, Alex Gurevich

Physics Faculty Publications

We present theoretical and numerical investigations of vortices driven by strong dc and ac currents in long Josephson junctions described by a nonlinear integro-differential equation which takes into account nonlocal electrodynamics of films, vortex bremsstrahlung, and Cherenkov radiation amplified by the attraction of vortices to the edges of the junction. This work focuses on the dynamics of vortices in Josephson junctions in thin films where the effects of Josephson nonlocality are essential but London screening is negligible. We obtained an exact solution for a vortex driven by an arbitrary time-dependent current in an overdamped junction where the vortex turns into …


Seebeck Coefficient Measurements Of Polycrystalline And Highly Ordered Metal-Organic Framework Thin Films, Xin Chen, Zhenbang Wang, Zeinab M. Hassan, Pengtao Lin, Kai Zhang, Helmut Baumgart, Engelbert Redel Jan 2017

Seebeck Coefficient Measurements Of Polycrystalline And Highly Ordered Metal-Organic Framework Thin Films, Xin Chen, Zhenbang Wang, Zeinab M. Hassan, Pengtao Lin, Kai Zhang, Helmut Baumgart, Engelbert Redel

Electrical & Computer Engineering Faculty Publications

In this work highly oriented Surface Anchored Metal-Organic Framework (SURMOF) films were fabricated quasi-epitaxial and were electrically characterized by Seebeck analysis and benchmarked against random polycrystalline MOF films loaded with tetracyano-quinodimethane (TCNQ) infiltration. The horizontal Seebeck coefficient of the oriented SURMOF films and the random polycrystalline MOF films parallel to the sample surface was measured and has been discussed. The isotropic random polycrystalline MOF films exhibit a high positive Seebeck coefficient of 422.32 μV/K at 350 K. However, the horizontal Seebeck coefficient of highly oriented SURMOF films fluctuates around 0 μV/K instead. Because the quasi-epitaxial oriented SURMOF films are highly …


Quantitative Analysis Of X-Ray Fluorescence Absorption And Emission For Thickness Determination Of Ald-Grown Metal And Oxide Nanoscaled Films, Tarek M. Abdel-Fattah, Alex Wixtrom, Larry Arias, Kai Zhang, Helmut Baumgart Jan 2017

Quantitative Analysis Of X-Ray Fluorescence Absorption And Emission For Thickness Determination Of Ald-Grown Metal And Oxide Nanoscaled Films, Tarek M. Abdel-Fattah, Alex Wixtrom, Larry Arias, Kai Zhang, Helmut Baumgart

Electrical & Computer Engineering Faculty Publications

This study describes the use of X-ray fluorescence spectroscopy (XRF) to determine the thickness of nanoscaled thin films of insulating oxides such as Al2O3, HfO2, and ZrO2, semiconducting oxides such as TiO2, ZnO, and metals like Pt, on silicon substrates synthesized by atomic layer deposition (ALD) technology. XRF thickness measurements were compared with the predicted layer thickness based on calculations from known ALD growth rates for each metal or metal oxide films. The ALD growth rates have been calibrated with TEM cross-sectional measurements of the resulting film thickness. The results …


Teaching Hands-On Cyber Defense Labs To Middle School And High School Students: Our Experience From Gencyber Camps, Peng Jiang, Xin Tian, Chunsheng Xin, Wu He Jan 2017

Teaching Hands-On Cyber Defense Labs To Middle School And High School Students: Our Experience From Gencyber Camps, Peng Jiang, Xin Tian, Chunsheng Xin, Wu He

Electrical & Computer Engineering Faculty Publications

With the high demand of the nation for next generation cybersecurity experts, it is important to design and provide hands-on labs for students at the K-12 level in order to increase their interest in cybersecurity and enhance their confidence in learning cybersecurity skills at the young age. This poster reports some preliminary analysis results from the 2016 GenCyber summer camp held at Old Dominion University (ODU), which is part of a nationwide grant program funded by the National Security Agency (NSA) and the National Science Foundation (NSF). This poster also demonstrates the design of three hands-on labs which have been …


Siso Output Affine Feedback Transformation Group And Its Faá Di Bruno Hopf Algebra, W. Steven Gray, Kurusch Ebrahimi-Fard Jan 2017

Siso Output Affine Feedback Transformation Group And Its Faá Di Bruno Hopf Algebra, W. Steven Gray, Kurusch Ebrahimi-Fard

Electrical & Computer Engineering Faculty Publications

The general goal of this paper is to identify a transformation group that can be used to describe a class of feedback interconnections involving subsystems which are modeled solely in terms of Chen-Fliess functional expansions or Fliess operators and are independent of the existence of any state space models. This interconnection, called an output affine feedback connection, is distinguished from conventional output feedback by the presence of a multiplier in an outer loop. Once this transformation group is established, three basic questions are addressed. How can this transformation group be used to provide an explicit Fliess operator representation of …


Industrial Wireless Sensor Networks 2016, Qindong Sun, Schancang Li, Shanshan Zhao, Hongjian Sun, Li Xu, Arumugam Nallamathan Jan 2017

Industrial Wireless Sensor Networks 2016, Qindong Sun, Schancang Li, Shanshan Zhao, Hongjian Sun, Li Xu, Arumugam Nallamathan

Information Technology & Decision Sciences Faculty Publications

The industrial wireless sensor network (IWSN) is the next frontier in the Industrial Internet of Things (IIoT), which is able to help industrial organizations to gain competitive advantages in industrial manufacturing markets by increasing productivity, reducing the costs, developing new products and services, and deploying new business models.


Qos Recommendation In Cloud Services, Xianrong Zheng, Li Da Xu, Sheng Chai Jan 2017

Qos Recommendation In Cloud Services, Xianrong Zheng, Li Da Xu, Sheng Chai

Information Technology & Decision Sciences Faculty Publications

As cloud computing becomes increasingly popular, cloud providers compete to offer the same or similar services over the Internet. Quality of service (QoS), which describes how well a service is performed, is an important differentiator among functionally equivalent services. It can help a firm to satisfy and win its customers. As a result, how to assist cloud providers to promote their services and cloud consumers to identify services that meet their QoS requirements becomes an important problem. In this paper, we argue for QoS-based cloud service recommendation, and propose a collaborative filtering approach using the Spearman coefficient to recommend cloud …