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Full-Text Articles in Biological Engineering
Nanofiber Scaffolds As 3d Culture Platforms, Stephanie Bule
Nanofiber Scaffolds As 3d Culture Platforms, Stephanie Bule
Dissertations, Master's Theses and Master's Reports
Cell culture has become the basis for understanding the fundamental mechanisms of cell, tissue and organ function. Although major advancements in uncovering the underlying processes and mechanisms of normal and diseased cell biology have been made by using two-dimensional (2D) cell culture, there is a recent shift in moving towards three-dimensional (3D) culture platforms. The motivation is to better recapitulate the microenvironment of cells in vivo to obtain results that are more indicative to actual cellular processes. In this study, electrospun nano-fibrous scaffolds made of polycaprolactone were used as a 3D culture tool to investigate difference in cell behavior and …
Systematic Study Of The Biological Effects Of Nitric Oxide (No) Using Innovative No Measurement And Delivery Systems, Weilue He
Dissertations, Master's Theses and Master's Reports
Nitric oxide (NO) is recognized as the most important small signaling molecule in the human body. An imbalance of NO is closely associated with many serious diseases such as neurological disorders, cardiovascular diseases, chronic inflammations and cancers. Herein two chemiluminescence-based devices (a real-time NO measurement device and a controllable NO delivery device) were developed to facilitate the NO quantitative study and obtain information for NO related drug design.
The first device used for real-time measuring NO(g) flux from living cells was developed and validated. The principle was to use a two-chamber design, with a cell culture chamber and a gaseous …
Application Of Aspen Mads-Box Genes To Alter Reproduction And Development In Trees, Gopi Krishna Podila, Leland James Cseke, Banalata Sen, David F. Karnosky
Application Of Aspen Mads-Box Genes To Alter Reproduction And Development In Trees, Gopi Krishna Podila, Leland James Cseke, Banalata Sen, David F. Karnosky
Michigan Tech Patents
The present invention provides compositions and methods for producing a transgenic plant that exhibits altered characteristics resulting from over expression or under expression of a novel polypeptide PtM3 or its homolog PtM4. The altered characteristics resulting from over-expression include at least one of the ability to convert axillary mer- istem to floral meristem; to accelerate flowering i.e., early flowering; to increase fruit production; to increase nut production; to increase seed output; to increase branching; to increase flower production; to increase fruit yield; to increase flower yield and a combination thereof. The altered characteristics resulting from suppressed expression include at least …
Genetic Engineering Of Plants Through Manipulation Of Lignin Biosynthesis, Vincent Lee C. Chiang, Chung-Jui Tsai, Wen-Jing Hu
Genetic Engineering Of Plants Through Manipulation Of Lignin Biosynthesis, Vincent Lee C. Chiang, Chung-Jui Tsai, Wen-Jing Hu
Michigan Tech Patents
The invention pertains to the genetically down regulating a lignin pathway p-coumarate Co-enzyme A ligase (CCL) in trees.
Genetic Transformation And Regeneration Of Plants, Vincent Lee C. Chiang, Chung-Jui Tsai, Gopi K. Podila
Genetic Transformation And Regeneration Of Plants, Vincent Lee C. Chiang, Chung-Jui Tsai, Gopi K. Podila
Michigan Tech Patents
An Agrobacterium-mediated transformation and regeneration method for plants including a transformation method to produce transgenic plants with an altered lignin composition.