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Biological Engineering Commons

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Full-Text Articles in Biological Engineering

Handling And Manipulation Of Water- And Air- Borne Biological Samples Using Liquid-Infused Surfaces, Daniel P. Regan Apr 2021

Handling And Manipulation Of Water- And Air- Borne Biological Samples Using Liquid-Infused Surfaces, Daniel P. Regan

Electronic Theses and Dissertations

Research on novel materials to handling water- and airborne samples for biological threats analysis is in great demand due to the COVID-19 pandemic. Work conducted on a new field of material science, called liquid-infused surfaces, demonstrate strong potential for the handling and manipulation of biological samples. As a result of the field’s infancy, only a limited number of studies have explored how liquid-infused surfaces can apply droplet manipulation strategies to address real-world problems. Presented in this dissertation are two platforms that leverage liquid-infused surfaces to address the challenges associated with handling water- and airborne biological samples. When dealing with waterborne …


A Multi-Channel 3d-Printed Bioreactor For Evaluation Of Growth And Production In The Microalga Dunaliella Sp, Cristian A. Cox Dec 2016

A Multi-Channel 3d-Printed Bioreactor For Evaluation Of Growth And Production In The Microalga Dunaliella Sp, Cristian A. Cox

Electronic Theses and Dissertations

We explored the capabilities of additive manufacturing using a photo-cured jetted material 3D printer to manufacture a milli-microfluidic device with direct application in microalgae Dunaliella sp growth and intracellular compounds biosynthesis tests. A continuous microbioreactor for microalgae culture was CAD designed and successfully built in 1 hour and 49 minutes using black photopolymer cured by UV and a support material. The microreactor was made up of 2 parts including the bioreactor itself and a microchannel network for culture media fluids and microalgae. Both parts were assembled to form a single unit. Additional optical and auxiliar components were added. An external …


Development Of Porous Polymeric Implants For Use In Orthopedic Research And Development Applications, Alexander Caddell Apr 2012

Development Of Porous Polymeric Implants For Use In Orthopedic Research And Development Applications, Alexander Caddell

Honors College

Current orthopedic implants comprised of plastic, ceramic, or metal alloys are susceptible to surface degradation at the implant-implant interface. The resulting microscopic fragments cause tissue irritation that can lead to osteolysis. In addition, existing percutaneous implants, such as pins used to stabilize fractures, are prone to bacterial infections due to the inability of the surrounding soft tissue to adhere to the implant and form a biologic seal. The goal of this Honors Thesis was to develop porous polymeric implants for orthopedic research and development applications that improve upon current designs in an attempt to remedy the issues detailed above. A …