Engineering Commons^™

Capillary And Microchip Electrophoresis For The Monitoring Of Disease Causing Amyloid Proteins, Elizabeth Nancy Pryor

Graduate Theses and Dissertations

The detection of oligomers and aggregates formed by two amyloid proteins, insulin and amyloid-beta (AB), is of particular importance due to the role which these species play in Diabetes and Alzheimer's disease, respectively. However, existing techniques are limited in the ability to detect insulin and AB; oligomers due to the fact that these early aggregates are transient, present at low concentrations, and difficult to isolate. Improvements must be made to existing techniques or alternative techniques must be explored in order to identify and quantify the size of these oligomeric and aggregate species without disrupting their structure.

Capillary and microchip electrophoresis …

A Silicon Carbide Based Solid-State Fault Current Limiter For Modern Power Distribution Systems, Erik Darnell Johnson

Graduate Theses and Dissertations

The fault current limiter represents a developing technology which will greatly improve the reliability and stability of the power grid. By reducing the magnitude of fault currents in distribution systems, fault current limiters can alleviate much of the damage imposed by these events. Solid-state fault current limiters in particular offer many improved capabilities in comparison to the power system protection equipment which is currently being used for fault current mitigation. The use of silicon carbide power semiconductor devices in solid-state fault current limiters produces a system that would help to advance the infrastructure of the electric grid.

A solid-state fault …

Plasmonic And Photonic Designs For Light Trapping In Thin Film Solar Cells, Liming Ji

Graduate Theses and Dissertations

Thin film solar cells are promising to realize cheap solar energy. Compared to conventional wafer cells, they can reduce the use of semiconductor material by 90%. The efficiency of thin film solar cells, however, is limited due to insufficient light absorption. Sufficient light absorption at the bandgap of semiconductor requires a light path more than 10x the thickness of the semiconductor. Advanced designs for light trapping are necessary for solar cells to absorb sufficient light within a limited volume of semiconductor. The goal is to convert the incident light into a trapped mode in the semiconductor layer.

In this dissertation, …

A Novel Microfluidic Enrichment Technique For Carbonylated Proteins, Bryant C. Hollins

Doctoral Dissertations

Proteins are the building blocks of cells in living organisms, and are composed of amino acids. The expression of proteins is regulated by the processes of transcription and translation. Proteins undergo post-translational modifications in order to dictate their role physiologically within a cell.

Not all post-translational modifications are beneficial for the protein or the cell. One type of post-translational modification, called carbonylation, irreversibly places a carbonyl group onto an amino acid residue, most commonly proline, lysine, arginine, and threonine. This modification can have severe consequences physiologically, including loss of solubility, loss of function, and protein aggregation.

Carbonylated proteins have commonly …

Risk Analysis And Reliability Improvement Of Mechanistic-Empirical Pavement Design, Xingqiang Danny Xiao

Graduate Theses and Dissertations

Reliability used in the Mechanistic Empirical Pavement Design Guide (MEPDG) is a congregated indicator defined as the probability that each of the key distress types and smoothness will be less than a selected critical level over the design period. For such a complex system as the MEPDG which does not have closed-form design equations, classic reliability methods are not applicable. A robust reliability analysis can rely on Monte Carlo Simulation (MCS). The ultimate goal of this study was to improve the reliability model of the MEPDG using surrogate modeling techniques and Monte Carlo simulation.

To achieve this goal, four tasks …

Effects Of Testing Time On Anaerobic Toxicity Assessment, Omolola Atinuke Akintomide

Graduate Theses and Dissertations

Anaerobic digestion has been widely used for wastewater treatment for decades. Several Anaerobic Toxicity tests have been developed to screen wastewater for toxicity and assess the treatability of such toxicants. However, past research and reviews on Biochemical Methane Potential (BMP) test and Anaerobic Toxicity Assay (ATA) were considered in this study.

The experimental tests included ammonium-nitrogen and sodium chloride toxicity tests with varied concentration and solid retention time. These tests were designed to demonstrate the impact of ammonia- nitrogen and sodium chloride on the biological degradation process. The anaerobic test set-up includes bench-scale test reactors and respirometers used for measuring …

Magnitude And Frequency Of Floods For Rural, Unregulated Streams Of Tennessee By L-Moments Method, Hongxiang Yan

Graduate Theses and Dissertations

This study presents a regional frequency analysis of Tennessee using the well-known Bulletin-17B method standardly used in the United States and the relatively new and developing L-Moments methods. Flood frequency characteristics were defined for 416 gaging stations located primarily in rural and lightly developed areas of Tennessee. All the gaging stations have 10 or more years of record through 2006. Using the L-Moments method, the generalized extreme value distribution was identified as the most robust distribution for each of four hydrologic areas. Multiple regression equations were also calculated for estimating the flood frequency of ungaged, unregulated, rural streams in each …

The Development Of A High Performance Concrete To Store Thermal Energy For Concentrating Solar Power Plants, Emerson Esmond John

Graduate Theses and Dissertations

In recent years, due to rising energy costs as well as an increased awareness of the environmental effects of greenhouse gas emissions produced through traditional forms of energy production, there is great interest in developing alternative sources of energy. One of the most viable alternative energy sources is solar energy. In particular, concentrating solar power (CSP) technologies have been identified as an option for meeting utility needs in the U.S. Southwest. These systems are required to produce electricity not only during periods of high solar radiation but also during times of reduced radiation due to cloud cover, and even extend …

Investigating The Bond Of Prestressing Strands In Lightweight Self-Consolidating Concrete, Royce Woodrow Floyd

Graduate Theses and Dissertations

Lightweight self-consolidating concrete (LWSCC) is a relatively recent advancement in concrete technology. The reduced dead load from lightweight concrete is beneficial for precast elements and for elements where dead load is a significant portion of the total load, such as prestressed bridge girders. Self-consolidating concrete (SCC) is a specially proportioned concrete mixture that consolidates under its own weight without the need for vibration. The combination of lightweight concrete and self-consolidating behavior provides the benefits of both. Bond of prestressing steel has been a much debated topic since the 1950s. Limited data are available on the transfer and development length of …

Improved Protocols For Automated Wheelpath Crack Detection In Pavements, Daniel Patrick Byram

Graduate Theses and Dissertations

Roadway pavement distress evaluations are vital to understanding the mechanics of pavement stability, determining the distribution of rehabilitation costs, and knowing the appropriate rehabilitation strategies. Advancements in technology over the past two decades have changed the way these surveys have been performed by means of automated data collection and interpretation. More and more state agencies have invested in automated road analyzing vehicles that are able to collect high resolution images of the pavement. Fewer have adopted automated data processing software with the ability to interpret road distresses due to the common discrepancies in distress classification algorithms.

In addition to automated …

New Insights Into Disinfection Byproduct Formation And Control: Assessing Dissolved Organic Matter Diffusivity And Chemical Functionality, Ashley Pifer

Graduate Theses and Dissertations

Methods were developed for application of asymmetric flow field-flow fractionation (AF4) and fluorescence parallel factor (PARAFAC) analysis to raw and treated samples from drinking water sources to improve characterizations of dissolved organic matter (DOM) and discover DOM properties correlated to disinfection byproduct (DBP) formation potential (FP). Raw water samples were collected from a reservoir, adjusted to pH 6, 7, and 8 and subjected to (1) jar tests using aluminum sulfate (alum) and (2) treatment with magnetic ion exchange (MIEX^®) resin. Both treatments were followed by DBPFP tests at pH 7. AF4 was used to size DOM in raw …

Wheel Path Wandering Based On Field Data, Wenting Luo

Graduate Theses and Dissertations

The position and width of wheel path on a pavement lane is an important consideration in conducting pavement distress survey, especially for distinguishing longitudinal cracking from fatigue cracking. Currently, the widely used wheel path definition is derived from the LTPP distress manual with fixed width and position, in which the influence of traffic wander on wheel path was overlooked. This thesis attempts to develop a new wheel path definition based on the lateral placement investigation of heavy vehicles' wandering in the field. Generally, the factors influencing vehicle lateral placement can be divided into seven categories, but only four factors are …

Load Sensor In An Elastomer Suspension Element, Jazmin Ley

Theses and Dissertations - UTB/UTPA

Knowledge of the loading applied to railcar suspension elements is necessary for improved rail safety, efficiency, and for monitoring bearing health. An economical, reliable system for keeping track of both dynamic and static loads on a rail car bearing offers potential for many improvements in rail service. The difficulties of implementing such a system are considerable because the sensor must be in the bearing load path and is thus subject to all the stressors of that environment including high impact, high load, high temperature, and corrosion. This thesis describes an attempt to incorporate a load measurement system in a polyurethane …

Modeling The Adoption Of Identification Standards Within The Healthcare Supply Chain, Angelica Burbano

Graduate Theses and Dissertations

The adoption of identification standards and its associated technology in the healthcare supply chain has been slow over the past twenty five years, despite the evidence of the benefits that can be achieved. The widespread use of identification standards in the form of barcode labeled medical products can contribute to the reduction of point of care errors and can increase the efficiency of healthcare supply chain related processes. This research is focused on the analysis of the adoption of identification standards in the healthcare supply chain with a particular focus on the healthcare provider adoption challenges. The research is divided …

Characterization And Quantification Of Monomers, Oligomers, And By-Products From Xylan During Biomass Pretreatment, Ching-Shuan Lau

Graduate Theses and Dissertations

Biomass pretreatment generates inhibitory products, which reduce the overall yield of xylose for ethanol production. Understanding of hemicellulose depolymerization into xylose is essential to identify the pretreatment conditions that maximize xylose formation, but minimize the generation of these inhibitory products, such as formic acid and furfural. Thus, the goal of this project is to understand how dilute acid pretreatment parameters affect hemicellulose depolymerization, maximize xylose concentrations, and minimize by-products formation.

To progress towards this goal, rates and mechanisms of hemicellulose release must be determined. Birchwood xylan was used as the starting material to produce xylose oligomers. The hydrolyzed birchwood xylan …

Locating And Protecting Facilities Subject To Random Disruptions And Attacks, Hugh Medal

Graduate Theses and Dissertations

Recent events such as the 2011 Tohoku earthquake and tsunami in Japan have revealed the vulnerability of networks such as supply chains to disruptive events. In particular, it has become apparent that the failure of a few elements of an infrastructure system can cause a system-wide disruption. Thus, it is important to learn more about which elements of infrastructure systems are most critical and how to protect an infrastructure system from the effects of a disruption. This dissertation seeks to enhance the understanding of how to design and protect networked infrastructure systems from disruptions by developing new mathematical models and …

Dynamical Properties Of Ferroelectric Perovskites (Ba,Sr)Tio3 And Pb(Zr,Ti)O3 Systems From First Principles, Jeevaka Weerasinghe

Graduate Theses and Dissertations

A first-principles-based effective Hamiltonian scheme which incorporates coupling between ferroelectric (FE) and antiferrodistortive (AFD) motions is applied to Pb(Zr,Ti)O₃ alloys. It validates the existence of two modes of E symmetry (rather than the single E(1TO) soft mode) in the 50-75 cm^-1 range for temperatures smaller than 200 K and for compositions falling within the Rhombohedral R3c phase. Coupling between long-range-ordered FE and AFD motions is shown to be the cause of the additional mode and more insight into its nature is provided. This scheme is further used to reveal a field-induced anticrossing involving FE and AFD degrees of …

Flexible Circuits For Aerospace Applications With Special Emphasis On Rf Connectors, Abhishek Nareshraj Singh

Graduate Theses and Dissertations

The current work focused on the study of flexible electronic circuits for use in aerospace applications with emphasis on RF Connectors. The electrical and mechanical performance of the flexible circuits was studied and compared to a standard coaxial cable for feasibility study in avionics space. Also, Anisotropic Conductive Films (ACF) are studied for connecting the flexible RF connectors and their performance studied for electrical and mechanical behavior with change in bonding parameters.

Comparison Of Various Pipelined And Non-Pipelined Scl 8051 Alus, Jingyi Zhao

Graduate Theses and Dissertations

This paper describes the development of an 8-bit SCL 8051 ALU with two versions: SCL 8051 ALU with nsleep and sleep signals and SCL 8051 ALU without nsleep. Both versions have combinational logic (C/L), registers, and completion components, which all utilize slept gates. Both three-stage pipelined and non-pipelined designs were examined for both versions. The four designs were compared in terms of area, speed, leakage power, average power and energy per operation. The SCL 8051 ALU without nsleep is smaller and faster, but it has greater leakage power. It also has lower average power, and less energy consumption than …

Atomistic Simulations Of Defect Nucleation And Intralayer Fracture In Molybdenum Disulphide During Nanoindentation, James A. Stewart

Graduate Theses and Dissertations

Molybdenum disulphide (MoS2) is a layered, hexagonal crystal that has a very low coefficient of friction. Due to this low coefficient of friction, MoS2 has become a well-known solid lubricant and liquid lubricant additive. As such, nanoparticles of MoS2 have been proposed as an additive to traditional liquid lubricants to provide frictional properties that are sensitive to different temperature and pressure regimes. However, to properly design these MoS2 nanoparticles to be sensitive to different temperature and pressure regimes, it is necessary to understand the mechanical response of crystalline MoS2 under mechanical loading. Specifically, the fundamental mechanism associated with the nucleation …

2d Modeling Of Forcespinning™ Nanofiber Formation With Experimental Study And Validation, Simon Padron

Theses and Dissertations - UTB/UTPA

A newly developed method of producing nanofibers, called Forcespinning™, has proven to be a viable alternative to mass produce nanofibers. Forcespinning™ utilizes centrifugal forces which allow for a host of new materials to be processed into nanofibers while also providing a significant increase in yield and ease of production. To improve and enhance the Forcespinning™ production method, a 2D computational Forcespinning™ fluid dynamics model is developed. Three computer models, namely time-independent and time-dependent inviscid models and a viscous model are obtained and the influences of various parameters on Forcespinning™ fiber formation are obtained. This work also presents a detailed explanation …

Electromagnetic Interference Shielding Effectiveness Of Metallic Thin Films Deposited On High Density Polyethylene And Styrene Butadiene Copolymer Reinforced With Carbon Nanofibers, Horus Garcia

Theses and Dissertations - UTB/UTPA

Aluminum, Copper and Silver were deposited by thermal evaporation onto Vapor Grown Carbon Nanofiber (VGCNF) reinforced High Density Polyethylene (HDPE) and Styrene Butadiene Copolymer (SBC) composites. Electromagnetic Interference Shielding Effectiveness (EMI SE) was conducted on the structures to analyze the synergistic effect. Characterization was performed by Scanning Electron Microscopy, X-ray Diffraction, and Atomic Force Microscopy. Adhesion test and surface influence on SE were also performed. It was observed that a single layer metallic thin film on carbon nanofiber (CNF) polymer composite experienced a summation of shielding performance. The EMI SE increased with CNF content increase of 10, 15, and 20 …

Remanufacturing Cleaning Process Evaluation, Comparison And Planning, Ozan Yagar

Theses and Dissertations - UTB/UTPA

This thesis aims to combine previous research on remanufacturing cleaning processes and applications into a single decision-making tool, in the form of software, which a remanufacturer can use to find a cleaning system that matches their specific demands. This thesis will provide an in-depth review of each cleaning process, the chemicals used in those processes, and the contamination types for which they were developed. This research also provides evaluation and comparison that assists remanufacturers in designing their cleaning systems. Finally, there will be a description and demonstration of the software. The ultimate goal is to find correct cleaning process to …

A Case Study For Financial Feasibility Of Automated Costing Support In A Small Machine Shop, Benito A. Gonzalez

Theses and Dissertations - UTB/UTPA

A knowledge-based cost estimating expert system is chosen by a Mexican machine shop. Differences between the traditional experience-based system employed and the automated system are studied. Data is gathered to analyze time effectiveness, accuracy and payback of the software. Data from seventy part models is recorded to study the time experiment, and data from fifty part models is used to study the accuracy and consistency. Data is analyzed by calculating mean, standard deviation, and test of hypothesis. The results indicate that the software is faster than the traditional quoting system; however, the payback point is high. Also, results show the …

Ultra-Low Voltage Digital Circuits And Extreme Temperature Electronics Design, Aaron J. Arthurs

Graduate Theses and Dissertations

Certain applications require digital electronics to operate under extreme conditions e.g., large swings in ambient temperature, very low supply voltage, high radiation. Such applications include sensor networks, wearable electronics, unmanned aerial vehicles, spacecraft, and energyharvesting systems. This dissertation splits into two projects that study digital electronics supplied by ultra-low voltages and build an electronic system for extreme temperatures. The first project introduces techniques that improve circuit reliability at deep subthreshold voltages as well as determine the minimum required supply voltage. These techniques address digital electronic design at several levels: the physical process, gate design, and system architecture. This dissertation analyzes …

Peptoid Based Slide Coatings For Disease Detection Via Elisa Microarray Analysis, Melissa Lea Hebert

Graduate Theses and Dissertations

Poly-N-substituted glycines (peptoids) are a very versatile family of synthetic molecules that can be customized for any number of applications. In this study, we chose to use peptoids as a foundation for sandwich ELISA microarray analysis with a long term goal of creating an early detection device for complex diseases such as cancer. The peptoids were designed to self-assemble into microspheres to be used in coatings on the surface of the microarray substrates to increase the surface area available for antibody attachment. This increased antibody density would lead to an increase in the microarray analysis sensitivity and dynamic range. Studies …

Optimization Of A Dynamic Hot Water Pretreatment Of Switchgrass Using Catalysis By Carbonation To Maximize Carbochemical Yields, Rohit Tanaji Dhamdere

Graduate Theses and Dissertations

A bio-refinery is a facility that converts renewable bio-resources into value-added chemicals and products. In this context of a bio-refinery, the production of the carbochemicals such as HMF, furfural and organic acids illustrate that multiple products can be produced from a renewable source such as lignocellulosic biomass (switchgrass). Traditionally, carbochemicals such as furfural and HMF are produced using inorganic acids such as H2SO4, HCL, and H3PO4. The use of such acids requires the application of high cost materials of construction such as Hastelloy-C, titanium etc.

The objective of this study is to develop a semi-continuous process for the conversion of …

Fabrication And Characterization Of Thinner Solid-State Nanopores, Denis Forbi Tita

Graduate Theses and Dissertations

Solid State nanopores that are fabricated by the ion beam sculpting process and electron beam drilling have shown great promise as a sensing device for DNA and protein molecules. Even though biological pores such as the alpha-Haemolysin have been in use for quite some time, the use of solid state Nanopores in single biomolecule detection has been on the rise since the mid 1990s. Solid State nanopores have an advantage over biological pores in that they are more robust, stable, and can be sculpted to any desired size for use in translocation experiments. One of the major challenges in Nanopore …

Delay Insensitive Ternary Logic Utilizing Cmos And Cntfet, Ravi Sankar Parameswaran Nair

Graduate Theses and Dissertations

As digital circuit design continues to evolve due to progress of semiconductor processes well into the sub 100nm range, clocked architectures face limitations in a number of cases where clockless asynchronous architectures require substantially less power, generate less noise, and produce less electromagnetic interference (EMI). This dissertation develops the Delay Insensitive Ternary Logic (DITL) asynchronous design paradigm that combines the designs aspects of similar Dual-Rail asynchronous paradigms and Boolean logic to create a single wire per bit, three voltage signaling and logic scheme.

DITL is designed at the transistor level using multi-threshold CMOS and carbon nanotube (CNT) FETs to develop …

Semiconductor Nanocrystals: From Quantum Dots To Quantum Disks, Zheng Li

Graduate Theses and Dissertations

The bottom-up colloidal synthesis opened up the possibility of finely tuning and tailoring the semiconductor nanocrystals. Numerous recipes were developed for the preparation of colloidal semiconductor nanocrystals, especially the traditional quantum dots. However, due to the lack of thorough understanding to those systems, the synthesis chemistry is still on the empirical level. CdS quantum dots synthesis in non-coordinating solvent were taken as a model system to investigate its molecular mechanism and formation process, ODE was identified as the reducing agent for the preparation of CdS nanocrystals, non-injection and low-temperature synthesis methods developed. In this model system, we not only proved …