Engineering Commons^™

A Multiwell Plate-Based System For Toxicity Screening Under Multiple Static Or Cycling Oxygen Environments, Ming Yao, Glenn Walker, Michael P. Gamcsik

Faculty and Student Publications

Tumor tissue contains a continuous distribution of static and dynamically changing oxygen environments with levels ranging from physiologically normal oxygen down to anoxia. However, in vitro studies are often performed under oxygen levels that are far higher than those found in vivo. A number of devices are available to alter the oxygen environment in cell culture, including designs from our laboratory. However, in our devices and most other designs, changing the media in order to feed or dose cells remains a disruptive factor in maintaining a consistent hypoxic environment. This report presents a novel 96-well plate design that recirculates the …

Factors Influencing The Usage Of Shared E-Scooters In Chicago, Farzana Mehzabin Tuli, Suman Mitra, Mariah B. Crews

Civil Engineering Faculty Publications and Presentations

The rapid popularity growth of shared e-scooters creates the necessity of understanding the determinants of shared e-scooter usage. This paper estimates the impacts of temporal variables (weather data, weekday/weekend, and gasoline prices) and time-invariant variables (socio-demographic, built environment, and neighborhood characteristics) on the shared e-scooter demand by using four months (June 2019-October 2019) period of data from the shared e-scooter pilot program in Chicago. The study employs a random-effects negative binomial (RENB) model that effectively models shared e-scooter trip origin and destination count data with over-dispersion while capturing serial autocorrelation in the data. Results of temporal variables indicate that shared …

Non-Closed Acoustic Cloaking Devices Enabled By Sequential-Step Linear Coordinate Transformations, Zahra Basiri, Mohammad Hosein Fakheri, Ali Abdolali, Chen Shen

Henry M. Rowan College of Engineering Departmental Research

Hitherto acoustic cloaking devices, which conceal objects externally, depend on objects' characteristics. Despite previous works, we design cloaking devices placed adjacent to an arbitrary object and make it invisible without the need to make it enclosed. Applying sequential linear coordinate transformations leads to a non-closed acoustic cloak with homogeneous materials, creating an open invisible region. Firstly, we propose to design a non-closed carpet cloak to conceal objects on a reflecting plane. Numerical simulations verify the cloaking effect, which is completely independent of the geometry and material properties of the hidden object. Moreover, we extend this idea to achieve a directional …

Investigation Of Human Adipose-Derived Stem-Cell Behavior Using A Cell-Instructive Polydopamine-Coated Gelatin-Alginate Hydrogel., Settimio Pacelli, Aparna R Chakravarti, Saman Modaresi, Siddharth Subham, Kyley Burkey, Cecilia Kurlbaum, Madeline Fang, Christopher A Neal, Adam J Mellott, Aishik Chakraborty, Arghya Paul

Chemical and Biochemical Engineering Publications

Hydrogels can be fabricated and designed to exert direct control over stem cells' adhesion and differentiation. In this study, we have investigated the use of polydopamine (pDA)-treatment as a binding platform for bioactive compounds to create a versatile gelatin-alginate (Gel-Alg) hydrogel for tissue engineering applications. Precisely, pDA was used to modify the surface properties of the hydrogel and better control the adhesion and osteogenic differentiation of human adipose-derived stem cells (hASCs). pDA enabled the adsorption of different types of bioactive molecules, including a model osteoinductive drug (dexamethasone) as well as a model pro-angiogenic peptide (QK). The pDA treatment efficiently retained …

Application Of Image Processing And Convolutional Neural Networks For Flood Image Classification And Semantic Segmentation, Jaku Rabinder Rakshit Pally

All Theses

Floods are among the most destructive natural hazards that affect millions of people across the world leading to severe loss of life and damage to property, critical infrastructure, and the environment. Deep learning algorithms are exceptionally valuable tools for collecting and analyzing the catastrophic readiness and countless actionable flood data. Convolutional neural networks (CNNs) are one form of deep learning algorithms widely used in computer vision which can be used to study flood images and assign learnable weights and biases to various objects in the image. Here, we leveraged and discussed how connected vision systems can be used to embed …

An Experimental And Computational Study Of 3-Dimensional Compact Windborne Debris Flight, Ta'jon Jordan

All Theses

In this thesis, the stochastic nature of 3-dimensional compact windborne debris flight is investigated experimentally and computationally. Previous literature (Holmes, 2004) analyzed the impact of strong winds on compact debris with applications to windborne debris flight. Baker (2007) derived the 2-dimensional equations of motion into a generalized dimensionless form that reveals the fundamental controlling parameters of compact debris flight. However, these models assume that compact debris is spherical, and the flight is, therefore, 2-dimensional. However most compact debris is not spherical, and its flight is 3-dimensional. Herein a previously developed model for free-falling compact windborne debris flight (Ahsanulllah et al., …

Deep Learning Strategies For Pool Boiling Heat Flux Prediction Using Image Sequences, Connor Heo

Graduate Theses and Dissertations

The understanding of bubble dynamics during boiling is critical to the design of advanced heater surfaces to improve the boiling heat transfer. The stochastic bubble nucleation, growth, and coalescence processes have made it challenging to obtain mechanistic models that can predict boiling heat flux based on the bubble dynamics. Traditional boiling image analysis relies on the extraction of the dominant physical quantities from the images and is thus limited to the existing knowledge of these quantities. Recently, machine-learning-aided analysis has shown success in boiling crisis detection, heat flux prediction, real-time image analysis, etc., whereas most of the existing studies are …

An Investigation Of The Flexural Strength And Toughness Of Hybrid Plain And Fiber Reinforced Concrete For Pavement Applications, Wesley Keys

Graduate Theses and Dissertations

For decades, many solutions have been evaluated to combat cracking in concrete pavements. The study presented in this paper evaluates and compares the flexural performance under a third point loading configuration of plain concrete (PC) beams, fully fiber reinforced concrete (FRC) beams, and hybrid PC and FRC beams, with a top PC and bottom FRC layer. The purpose of this hybrid approach was to provide FRC in only half the section, saving cost, while providing a PC surface layer that is easier to finish. All PC top layers were applied at an age of 7-days, considered a reasonable time for …

Retrospective Analysis Of Impacts Of Highway Bypass And Widening Projects, Sanjeev Bhurtyal

Graduate Theses and Dissertations

Community members often worry that highway projects may have negative impacts on their local economies. This is typical for highway bypass and widening projects in small cities (population less than 50,000). It is a challenge for planners to balance public concerns of economic decline with desired project outcomes of mobility and safety. Much of this challenge stems from a lack of information on post-project outcomes related to economic and safety impacts of new construction projects. Thus, there is a need for an evidence-based framework to help planners with the decision-making process and better inform the community on potential outcomes. This …

Nonmetallic Jet Impingement Thermal Management For Power Electronics Via Additive Manufacturing, Reece Whitt

Graduate Theses and Dissertations

The increase in energy demanded by transportation and energy sectors has necessitated highly efficient thermal management for reliable power electronics operations. Conventional cooling techniques are limited by their inability to target switching location hot spot temperatures, leading to non-uniform thermal gradients. These devices, such as cold plates and heat sinks, also utilize heavy metallic structures that can accentuate electromagnetic interferences generated by high voltage switching processes. This work proposes a non-metallic jet impingement cooler for more customized thermal management, while simultaneously reducing the harmful effects of electromagnetic interferences. Additive manufacturing is utilized to enable jet impingement zones to target individual …

Combined Stressors In Reliability Failure Modes In Flip-Chip Electronic Packaging, Mahsa Montazeri

Graduate Theses and Dissertations

The trend toward miniaturization of electronic devices to fulfill Moore’s law introduces new reliability concerns to the electronic packaging process while worsening existing primary challenges. In solder interconnect specifically, temperature cycling is one of the prominent failure threats. However, with further downscaling of the flip-chip solder connections, electromigration also present a precarious failure mode in these interconnects. On the other hand, understanding the degradation mechanism in solders is crucial for the power electronic products' reliability considering the industrial tendency to replace wirebonds with solder attachment while improving the current carry capacity. This dissertation utilizes FEA simulation and an experimental approach …

Mission Profile Effects On Automotive Drivetrain Electronics Reliability: Modeling And Mitigation, Bakhtiyar Mohammad Nafis

Graduate Theses and Dissertations

The reliability of electronic devices is dependent upon the conditions to which they are subject. Temperature variations coupled with differences in thermal expansion between bonded materials results in thermomechanical stresses to build up, which can instigate failure in the interconnects or other critical regions. With the move towards electrification in the automotive industry, there is the increasingly important consideration of powertrain electronics reliability, the pertinent conditions being governed by the drive cycle or mission profile of the vehicle. The mission profile determines the power dissipated by the electronic devices, which determines the peak and mean temperature, temperature swing and the …

Additive Manufacturing Of Soil Using Bio-Cementation, Christina Childress

Graduate Theses and Dissertations

Microbially Induced Calcite Precipitation (MICP) is an emerging soil treatment technique that is proven to increase strength, decrease erosion, reduce liquefaction risk, enhance slope stability, decrease compressibility, decrease swelling potential, and overall create a more competent soil. The benefits and applications of MICP are broad, and this research seeks to broaden them further by developing a single-phase additive manufacturing application with no treatment time delay. This is done by analyzing layering behaviors of five USCS soil classifications (100 % Ottawa sand, sand clay mixtures, and 100% lean clay) which provides insight into process variables such as the solution volume and …

Shear Strength Of Concrete Beams Made With Belitic Calcium Sulfoaluminate Cement, Caleb W. Chesnut

Graduate Theses and Dissertations

The need for a cleaner alternative to portland cement (PC) concrete has led to increasing interest in alternatives to PC. Structural properties of most of these alternative cements are still an open research topic. One promising alternative cement is belitic calcium sulfoaluminate (BCSA) cement. The study presented in this paper investigated the shear strength, long term compressive strength, and carbonation in BCSA cement and PC concrete beams. A total of twelve eight-foot long beams were made; eight BCSA cement concrete beams and four PC concrete beams to be tested at various ages depending on cement type. Two beams of each …

Thermometry Via Diffusion In Ferrous Core-Shell Nanoparticles For Induction Heating Applications, Hayden Carlton

Graduate Theses and Dissertations

Induction heating causes the release of enormous amounts of heat from dispersed magnetic nanoparticles. While the rate of heat transfer can be easily quantified calorimetrically, measuring the temperature of the nanoparticles on the nanoscale presents experimental challenges. Fully characterizing the temperature and thermal output of these magnetic particles is necessary to gauge overall heating efficiency and to provide a more holistic understanding of heat transfer on the nanoscale. Herein, this dissertation seeks to develop a novel nanoparticle thermometry technique, which correlates diffusion behavior in core-shell nanoparticles to local temperature. Initial measurements suggested that heating silica capped ferrous nanoparticles (SCNPs) via …

Improve The Prediction Of Camber, Deflection, And Prestress Losses In Precast, Prestressed Concrete Bridge Girders, Ahmed Ali Hussein Al Mohammedi

Graduate Theses and Dissertations

Many precast, prestressed concrete girders have camber less or higher than the design values. This discrepancy between the design and the actual camber creates construction problems when installing the cast-in-place concrete deck. The objective of this research was to improve the accuracy of estimating long-term camber, deflection, and prestress losses of precast, prestressed concrete girders.

The experimental program consisted of measuring concrete properties and performing field measurements of camber, deflection, and prestress losses for girders in Arkansas. The investigation involved testing nine full-scale girders from two prestressed concrete plants that regularly supply concrete girders to bridge projects in Arkansas. The …

Respiratory Compensated Robot For Liver Cancer Treatment: Design, Fabrication, And Benchtop Characterization, Mishek Jair Musa

Graduate Theses and Dissertations

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death in the world. Radiofrequency ablation (RFA) is an effective method for treating tumors less than 5 cm. However, manually placing the RFA needle at the site of the tumor is challenging due to the complicated respiratory induced motion of the liver. This paper presents the design, fabrication, and benchtop characterization of a patient mounted, respiratory compensated robotic needle insertion platform to perform percutaneous needle interventions. The robotic platform consists of a 4-DoF dual-stage cartesian platform used to control the pose of a 1-DoF needle insertion module. The active …

Hobby Grade Lithium-Ion Batteries For Spacecraft Applications: Establishing An Automated Electrical Characteristics Testing Procedure For Flight Acceptance Of Non-Space-Grade Small Secondary Batteries, Braidon Hughes

Graduate Theses and Dissertations

Li-ion batteries are widely used due to the large amount of rechargeable energy they pack into a small, light package. This higher energy density makes Li-ion batteries ideal for small satellite applications, specifically CubeSats. CubeSats have grown in popularity in higher level education due to the National Aeronautics and Space Administration’s implementation of the Cube Satellite Launch Initiative, making it easier and cheaper to conduct small, low orbit missions. Because these CubeSats are occupying the same space as a crewed spacecraft, it is imperative that they are safe. There are numerous reports of Li-ion batteries creating fires that result in …

Formation Of Reactive Nitrogen Species During Dichloramine Decay And Their Impact On N Nitrosodimethylamine Formation Under Drinking Water Conditions, Huong Thu Pham

Graduate Theses and Dissertations

NDMA occurrence and formation pathways in drinking water systems are reviewed and NDMA yields are compared on the basis of disinfectant type, water chemistry, and precursor category. In chloramination, despite monochloramine being the predominant species between pH 7-9, evidence suggests that dichloramine is the primary species involved in NDMA formation. This is somewhat confounding as NDMA yields are maximal at pH 9, yet at pH 9 dichloramine decays faster than it forms and hence is present at trace levels; additionally, the proposed mechanism involves a spin-forbidden incorporation of dissolved oxygen as a triplet, which is presumably kinetically slow. This review …

Factors Influencing The Usage Of Shared E-Scooters : A Case Study Of Chicago, Farzana Mehzabin Tuli

Graduate Theses and Dissertations

The rapid popularity growth of shared e-scooters creates the necessity of understanding the determinants of shared e-scooter usage. This thesis estimates the impacts of temporal variables (weather data, weekday/weekend, and gasoline prices) and time-invariant variables (socio-demographic, built environment, and neighborhood characteristics) on the shared e-scooter demand by using four months (June 2019- October 2019) period of data from the shared e-scooter pilot program in Chicago. The study employs a random-effects negative binomial (RENB) model that effectively models shared e-scooter trip origin and destination count data with over-dispersion while capturing serial autocorrelation in the data. Results of temporal variables indicate that …

2021 Fall Engr333 Seminar Presentation, Anika Huizinga, John Stehouwer, William Terpstra, Duncan Waanders

ENGR 333

File for student presentation, given by students in the Fall 2021 class of ENGR333.

Complete Modeling Of The Chondrogenic Environment Under Continuous Low-Intensity Ultrasound, Heather Newell

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Articular cartilage is an avascular tissue that requires therapeutic intervention methods. This work answers the following: determine transducer operation to optimize the bioeffects; calculate the magnitude of pressure exerted on chondrocytes at an injury site; and confirm the theoretical findings by an animal model.

Earlier work has shown that cellular response to US is maximized at the resonance frequency of the cells. Resonance frequencies were calculated for chondrocytes in various layers. The latter configuration closest resembles in vivo conditions and the resonance occurred at 3.8±0.3 ������. The 3D model of US propagation in a rabbit knee was constructed from MRIs …

Scalable Optimization Method For Generator Scheduling Under Uncertainty, Edward Arthur Quarm Jnr

Electrical Engineering Dissertations - Archive

Scalable optimization methods for power system operation has been subject of research over the last 60 years. State-of-the-art methods in this research area is yet to yield the scalability desired by system operators for practical operation of electric grids. This article-based dissertation makes three significant contributions. A scalable computational method is developed to tackle a mixed-integer problem commonly referred to as Stochastic Security-Constrained Unit Commitment (SSCUC), the output of which will be beneficial to Independent System Operators to manage electric grids. Secondly, an improved model for time-progressive contingencies in security-constrained optimization problems is presented. This modeling approach is more realistic …

Synthesis, Characterization And Tribological Properties Of Mo-Dlc, Tirth Ashishbhai Patel

Material Science and Engineering Theses - Archive

Diamond like carbon (DLC) films have been extensively used in a wide range of applications over the last decade due to their excellent mechanical and tribological properties. Metallic elements are used to dope DLC films in an effort to overcome some DLC limitations and make it compatible to use it in larger variety of applications. This study focuses on the effect of different processing parameters on DLC deposition, and the effect of Mo content on microstructure, mechanical and tribological properties. Plasma Enhanced Chemical Vapor Deposition (PECVD) technique coupled with magnetron sputtering is used in chamber atmosphere composed of CH4 and …

A Numerical Study Of Water Entry Problems Based On Overset Meshes, Yanni Chang

Mechanical and Aerospace Engineering Dissertations - Archive

A series of numerical experiments carried out on the water entry of circular cylinders are presented in this study. A cylinder was entering into the water with a prescribed inclined angle and velocity. The interface between water and air is tracked by the Piecewise Linear Interface Calculation (PLIC) schemes in conjunction with the Volume of Fluid (VOF) method. PLIC schemes have been extensively employed in the VOF method for interface capturing in numerical simulations of multiphase flows. Dynamic overset meshes, which have been widely used for problems with relative motions and complex geometric shapes, are applied to handle the moving …

Characterization And Enhancement Of Fatigue And Fracture Properties In Thermoplastic Fff Parts Using In-Situ Annealing, Manjarik Mrinal

Mechanical and Aerospace Engineering Dissertations - Archive

Fused filament fabrication (FFF) show high anisotropy and reduced mechanical properties as compared to conventional manufacturing techniques. This happens due to the poor interlaminar bonding between the layers, as a result of premature halt of bond healing process. Previous research works show multiple approaches to improve the bond quality to enhance the mechanical properties of FFF parts, however these are complex and expensive techniques. In this work a novel print head assembly is presented to offer a simple and effective solution by applying a thermal field to the part as it is being printed to preheat the previously deposited layer, …

Internal Pressure Response Of A Human Head Surrogate Model Subject To Variable Impact Loading With Finite Element Analysis, Aaron Ronald Jackson

Mechanical and Aerospace Engineering Theses - Archive

Traumatic brain injury (TBI) from blunt impacts to the head is a major cause of brain disease and dysfunction for thousands of people every year. Each year in the United States approximately 1 million TBI cases occur causing as many as 56,000 deaths and leaving nearly 90,000 individuals with long-term disabilities. Damage resulting from a TBI occurs on a multiscale level including the macroscopic, tissue, and neuron length scale. This research focuses on correlating the macroscopic blunt impact conditions to the internal pressure developed in the coup and countercoup for water and gelatin-filled head models. Two separate 3D printed models …

Synthesis And Characterization Of Graphene-Reinforced Polymer Filaments For Additive Manufacturing, Sean Menezes

Mechanical and Aerospace Engineering Theses - Archive

Fused Deposition Modeling (FDM) is a popular 3D printing process which uses a spool of thermoplastic polymer filament that is melted by the movable extruder printer head onto the bed to generate the required shape. The most used polymer filaments in FDM are Acrylonitrile Butadiene Styrene (ABS) and Poly Lactic Acid (PLA). However, these conventional polymer filaments have lower mechanical strength and are more susceptible to cracking as the cooler parts of the printed part shrink so much that they cause cracks to develop, leading to warping. The current investigation focuses on the synthesis of graphene, synthesis of polymer filaments …

Reverse Engineering To Create High Quality Polymer Parts Using Additive Manufacturing, Gurtej Singh Tarsem Singh Channa

Mechanical and Aerospace Engineering Theses - Archive

Reverse engineering is a process of recreating parts for which the tools no longer exist, reducing the cost of an original part by manufacturing it in-house or redesigning and improving the original part's function. This research demonstrates two methods to reverse engineer a part using Polyworks software, having it printed using an SLS printer and checking the accuracy of the printed part to the original scan. The part is first scanned using a Faro-Arm laser scanner to obtain the point cloud data. The two methods used to recreate and extract the STEP file are: • Exporting NURBS. • Exporting Features …

Development Of The Vehicle Configuration Compendium: A Comprehensive Data-Information-Knowledge System To Aid In High-Speed Vehicle Design, Stenila Simon

Mechanical and Aerospace Engineering Theses - Archive

The conceptual design phase is the most crucial phase in hypersonic vehicle design. Choices made during this phase will have significant impact on the success of the overall project and the feasibility of the end-product. Therefore, it is of utmost importance for the design decision-maker to be adequately informed of past-to-present projects throughout the aerospace community and lessons learned from them. This avoids wasting valuable time and resources for reinventing the wheel. There currently exists no one-stop solution in the aerospace industry to address the issue of lost data, information and knowledge in the field of high-speed vehicle design. The …