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Impact Of Secondary Reactive Species On The Apparent Decoupling Of Poly(Ethylene Glycol) Diacrylate Hydrogel Average Mesh Size And Modulus, Dany J. Munoz Pinto, S. Samavedi, B. Grigoryan, M. S. Hahn
Impact Of Secondary Reactive Species On The Apparent Decoupling Of Poly(Ethylene Glycol) Diacrylate Hydrogel Average Mesh Size And Modulus, Dany J. Munoz Pinto, S. Samavedi, B. Grigoryan, M. S. Hahn
Dany J. Munoz Pinto
Poly(ethylene glycol) diacrylate (PEGDA) hydrogels are widely used in biotechnology due to their in situ crosslinking capacity and tunable physical properties. However, as with all single component hydrogels, the modulus of PEGDA networks cannot be tailored independently of mesh size. This interdependence places significant limitations on their use for defined, 3D cell-microenvironment studies and for certain controlled release applications. The incorporation of secondary reactive species (SRS) into PEGDA hydrogels has previously been shown to allow the identification of up to 6 PEGDA hydrogel formulations for which distinct moduli can be obtained at consistent average mesh size (or vice versa). However, …