Engineering Commons^™

Development Of An Efficient Human Hepatocyte Culture Platform For Assessing Novel Therapeutic Efficacy Against Plasmodium Liver Parasites, Steven Patrick Maher

USF Tampa Graduate Theses and Dissertations

Malaria is a critical and global public health problem, affecting over 200 million people every year, resulting in over 500,000 deaths. A vaccine is not currently available and only one drug, primaquine, is effective against the dormant stages of Plasmodium vivax. Preclinical assessment of novel therapeutic drugs and vaccines is hampered by the lack of an in vitro liver model for P. falciparum and P. vivax. To provide a stable human hepatocyte-based culture platform for parasite development, we engineered a microfluidic bilayer device capable of both simple and complex culture methods, including perfusion and co-culture, to better understand the requirements …

Sustainable Development Of Biogas Resources In East Africa Using Transdisciplinary Design Models, Christopher M. Limiac

Open Access Theses

Installation of anaerobic digestion systems in urban developing communities has the potential to address multiple problems related to energy and sanitation in a combined systems approach. Anaerobic digesters are used to generate a relatively clean and rich source of energy in the form of biogas to address energy poverty issues. The design resources available for anaerobic digestion projects must be improved to provide greater technical support and project transparency. In order to develop holistic solutions to grand challenges like energy poverty, engineers must be prepared to operate with the complexities of diverse environments. Globalization and the improvement of transdisciplinary project …

Development Of A Public Education Website: Building Bridges Over Water, Angelina Mckee

Agricultural Education and Communication

Website created by Angelina McKee to educate the public about water resource issues. Water is the basic unit of life, water resources are the basis for what societies and ecosystems are founded upon. Water shortages and droughts are more prevalent in our ever-changing world. It is no shock that there are discrepancies between various stockholders on either sides of the dry riverbed. This senior project resulted in the development of a website that addresses global water resources, water use in California, water conservation, and water allocation. The website informs the public on water resources and related issues and will hopefully …

Cypress Construction Inc.: Scheduling And Estimating Quandaries For Small Scale Residential Builds, Thamar Alsayyar

Master of Technology Management Plan II Graduate Projects

This study evaluates the particular scheduling and estimating challenges faced by Cypress Construction Incorporated, a small, privately owned residential construction company based in Baltimore, Maryland. The study, via the usage of primary data collection in the form of personal interviews and site observations, determines the nature of the scheduling and estimating functions conducted by Cypress Construction Inc.’s owner This data is then analyzed to ascertain why the scheduling and estimating functions of Cypress Construction Inc. are unique to the firm and are in need of amelioration. Furthermore, the study includes a literature review to compare the experiences of Cypress Construction …

A Fesability Analysis Of A Novel Constructed Wetland Design Tool For Arusha, Tanzania, Michael R. Sheehan

Open Access Theses

While water is a resource necessary for all life, in Tanzania alone over 20 million people who live in rural areas have no access to improved water sources. Water stress is a major concern in rural Tanzania, where annual potential evaporation can outpace precipitation by hundreds of mm per year. There is a significant need for improved access to water sources for Tanzanians living in rural regions of Arusha. To improve access to water, both water quantity and quality need to be addressed in a treatment system. Various water collection and treatment systems were compared and contrasted through the lens …

Quality Assurance And Quality Control Correlations For The Dynamic Cone Penetrometer, Eshan Ganju

Open Access Theses

The Dynamic Cone Penetrometer (DCP) is a device that is used for the estimation of in situ compaction quality of constructed subgrades and embankments. It is a relatively inexpensive, light-weight and easy to use device that measures the dynamic penetration resistance of the compacted soil, from which an estimate of soil strength and stiffness characteristics can be made. Owing to its ease of use, many DOTs in the U.S. have employed the DCP in their compaction quality control procedures, and over the past few decades, extensive research has been carried out on the development of correlations between the results of …

Affluent Populations And Their Effect On Biological Diversity Through The Consumption Of Meat, Electronics, And Motor Vehicles, Melody Flores

Honors College Theses

The human has caused a far greater impact on the planet's biodiversity than any other species in existence, due to the impact of population, afflluence, and technology. This thesis will argue the importance of biological diversity and how affluent populations are reducing biodiversity through the consumption of meat, electronics, and motor vehicles. Aldo Leopold's "The Land Ethic" and Herman Daly's "The Impossibility Theorem", among others, create a rubric evaluating human activities and provide alternative views on economic impossibilities. Consumption is reviewed from an ecocentric perspective, a holistic outlook placing emphasis on the ecosystem. The reader will become cognizant of their …

A Framework For Web Object Self-Preservation, Charles L. Cartledge

Computer Science Theses & Dissertations

We propose and develop a framework based on emergent behavior principles for the long-term preservation of digital data using the web infrastructure. We present the development of the framework called unsupervised small-world (USW) which is at the nexus of emergent behavior, graph theory, and digital preservation. The USW algorithm creates graph based structures on the Web used for preservation of web objects (WOs). Emergent behavior activities, based on Craig Reynolds’ “boids” concept, are used to preserve WOs without the need for a central archiving authority. Graph theory is extended by developing an algorithm that incrementally creates small-world graphs. Graph theory …

Application Of Remotely Sensed Rainfall Data In Rainfall-Runoff Modelling. A Case Of Pangani River Basin, Tanzania, Joel Nobert

Tanzania Journal of Engineering and Technology (TJET)

Rainfall runoff modelling in a river basin is vital for number of hydrologic application including water resources assessment. However, rainfall data from sparse gauging stations are usually inadequate for modelling which is a major concern in Tanzania. This study presents the results of comparison of Tropical Rainfall Measuring Mission (TRMM) satellite rainfall products at daily and monthly time-steps with ground stations rainfall data; and explores the possibility of using satellite rainfall data for rainfall runoff modelling in Pangani River Basin, Tanzania. Statistical analysis was carried out to find the correlation between the ground stations data and TRMM estimates. It was …

Analysis Of Different Techniques For Improving Performance Of Flat Plate Solar Collectors For Fruits Drying, Godfrey Mbabaye

Tanzania Journal of Engineering and Technology (TJET)

Fruits drying had become a broader technology in fruits and vegetables value addition. The technology is reported to be a promising way of drying without incurring higher cost but its adaptation has not been feasible in rural areas. Solar dryers have been developed but its poor performance limits its applicability. In this study, several techniques for modifications of traditional solar collector were addressed. It was observed that, varying collector designs in different techniques, a range of collector performances can be archived. The research shows that, collector efficiency can be improved by 9.6% when employing double duct counter flow compared to …

The Impact Of Fuzzy Requirements On Medical Device Software Development, Martin Mchugh, Abder-Rahman Ali, Fergal Mccaffery

Conference papers

Any software development project can experience difficulties with unclear or vague requirements. Unfortunately, this problem can be experience two fold in regulated environments such as the medical device software development industry. In the medical device software development industry, development organisations must contend with vague or “fuzzy” both the customer and regulatory bodies. As new requirements are introduced they can have a knock on effect on other requirements. These requirements should be analysed to determine if they are conflicting, cooperative, mutually exclusive and irrelevant. Only when the requirement is classified can a clear method be established as how to integrate that …

A Model For Magnetic Drug Targeting In A Permeable Microvessel With Spherical Porous Carrier Particles, Precious Sibanda, Sachin Shaw

5th International Conference on Porous Media and Their Applications in Science, Engineering and Industry

We present a mathematical model for targeting a drug at malignant tissue cells in a permeable microvessel. The drug molecules are transported in carrier particles which are assumed to be porous spheres. This mode of drug delivery is non-invasive and has less toxic effects on healthy cells and tissues. The microvessel tube (see Figure 1) is subdivided into three regions, the outer endothelial glycocalyx layer where the blood has a Newtonian character, and a core and plug regions where the blood flow is described using a non-Newtonian Casson fluid model which is suitable for microvessels of radius 5mμ. Targeting is …

Comparative Analysis Of Geometric Models For Predicting The Dynamic Specific Surface Of Foamlike Media, Sonia Woudberg, Francois Smit

5th International Conference on Porous Media and Their Applications in Science, Engineering and Industry

An adaptable geometric pore-scale model is proposed for predicting the specific surface area of actual foams. The proposed model, based on rectangular geometry, is compared to a cubic unit cell model from the literature based on cylindrical struts, a tetrakaidecahedron model as well as a dodecahedron model (both based on either cylindrical of triangular struts). The predicted specific surface areas of the proposed model are of the same order of magnitude as the other model predictions from the literature. The relative percentage errors in the predicted values are at most equal to the relative percentage errors associated with the measured …

Low-Cost Household Groundwater Supply Systems For Developing Communities, Michael Maccarthy

USF Tampa Graduate Theses and Dissertations

ABSTRACT

Self-supply is widely reported across various contexts, filling gaps left by other forms of water supply provision. This research assesses low-cost household groundwater supply technologies in markets in developing country contexts of sub-Saharan Africa and Latin America, with a focus on the potential for improving Self-supply technology implementation and markets in sub-Saharan Africa. Specifically, a mature and unsubsidized Self-supply market for Pitcher Pump systems (suction pumps fitted onto hand-driven boreholes) is studied in an urban context in Madagascar, EMAS low-cost water supply technologies are assessed in Bolivia, and a technical comparison is completed with manual EMAS Pumps and family …

Program, Engineering Conferences International

5th International Conference on Porous Media and Their Applications in Science, Engineering and Industry

No abstract provided.

Dynamic Feedback Between Land Use And Hydrology For Ecosystem Services Assessment, Seleshi Getahun Yalew, Tobias Pilz, Christian Schweitzer, Stefan Liersch, Johannes Van Der Kwast, Marloes L. Mul, Ann Van Griensven, Pieter Van Der Zaag

International Congress on Environmental Modelling and Software

Ecosystem services assessment requires an integrated approach, as it is influenced by elements such as climate, hydrology and socio-economics, which in turn influence each other. However, there are few studies that integrate these elements in order to assess ecosystem services. Absence of integrated approach to modelling hydrological and land-use changes, for instance, often oversights the dynamic feedback between the two processes. Dynamic changes in land-use should be fed into hydrological models and vice-versa at each time-step for a more realistic representation. In this study, this approach is demonstrated with a case study of the uThukela catchment, South Africa. There is …

Business Intelligence In Environmental Reporting Powered By Xbrl, Jiří Hřebíček, Michal Hodinka, Michael Ŝtencl, Oldřich Trenz

International Congress on Environmental Modelling and Software

The paper discusses several critical points of the whole concept of Business lntelligence (Bl) approach to environmental reporting powered by XBRL. First, and most important, is the usage of structured data delivered via XBRL. The main profit on usage of XBRL is the optimization of the Extract, Transform and Load (ETL) process and its combination commonly used best practices on data warehouse models. The whole Bl workflow could be moved further by additional data quality health checks, extended mathematical and logical data test, basics of data discovery and drill-down techniques. The state of the art on the XBRL level and …

Investigating Possible Climate Change And Development Effects On Water Quality Within An Arid Catchment In South Africa: A Comparison Of Two Models, Andrew R. Slaughter, Sukhmani K. Mantel, Denis A. Hughes

International Congress on Environmental Modelling and Software

The water quality degradation of fresh water resources has become an increasingly urgent global problem which is predicted to be exacerbated by future development and climate change. Since water quality is to a large extent driven by water quantity, it is useful for a model to incorporate a rainfall-runoff component (natural hydrology), reservoir storage, return flows and abstractions (systems modelling), and a water quality component. One such model that meets these requirements is the Water Evaluation and Planning (WEAP) Model. During 2012, WEAP was applied to the Buffalo River within the Eastern Cape, South Africa, to investigate the effect on …

Extending Existing Models To Capture Vegetation Response To Extreme Weather Events: The Modextreme Project, Gianni Bellocchi, Francisco J. Villalobos, Marcello Donatelli, Ole B. Christensen, Oscar Rojas, Roberto Confalonieri, Ioannis N. Athanasiadis, Irina Carpusca, Claudio O. Stöckle

International Congress on Environmental Modelling and Software

Extreme weather events are combinations of meteorological drivers that exceed certain thresholds and occur with low frequency, negatively impacting human living conditions and economic systems including agriculture. The three-year European project MODEXTREME (started on November 1st, 2013) aims at improving the predictive capability of biophysical crop and grassland simulation models under extreme weather conditions (mainly high/low temperatures and water deficit/excess). Existing modelling solutions can be improved with re-usable software libraries to capture extreme weather impacts. Estimates from existing and new modelling solutions will be compared on a variety of datasets and evaluated with respect to medium-term trajectories of future climate …

Discovering Comprehensible Hydrogeological Profiles In The Margarita Island's Aquifers Including Post-Processing In A Data Mining Process, Conti Dante, Gibert Karina

International Congress on Environmental Modelling and Software

Groundwater wells are one of the most important water resources in the world. Control and management of these resources are of high importance due to the implicit need of water as the main resource for life. This research focuses on a hydrogeological analysis with clustering, which is one of the most popular data mining methods, including In the classical data mining scheme, last step corresponds to the effective production of knowledge. In this paper, special focus on that part is done, by means of post-processing tools. The main goal is to discover prototypical profiles from the acquifer Pedro González in …

Operational Flash Flood Warning Systems With Global Applicability, Theresa M. Modrick, Rochelle Graham, Eylon Shamir, Robert Jubach, Cristopher R. Spencer, Jason A. Sperfslage, Konstantine P. Georgakakos

International Congress on Environmental Modelling and Software

The availability of global meteorological information (observations and forecasts) and widespread digital data on the land surface now affords the use of hydrometeorological modelling in an operational environment to provide numerical guidance for local forecasts and warnings of flash flooding by meteorological and disaster management agencies, Flash floods are among the deadliest natural disasters and can have significant impact on the natural environment and infrastructure, Working with national meteorological and hydrologic services, the Hydrologic Research Center has developed and implemented regional software systems to convey remotely sensed data and guidance products for rapid decisions regarding flash flood warnings, The systems …

Wastewater Reuse In Apulia: Between Dream And Reality, Antonio Lopez

Wastewater and Biosolids Treatment and Reuse: Bridging Modeling and Experimental Studies

No abstract provided.

Simulation Based Feed Stream Estimation Of Wastewater Treatment Plants Using A Surrogate Model, Peter Kern

Wastewater and Biosolids Treatment and Reuse: Bridging Modeling and Experimental Studies

No abstract provided.

Large Wastewater Agricultural Reuse With Adaptive Nutrient Removal Case Study, Luca Pedrazzi

Wastewater and Biosolids Treatment and Reuse: Bridging Modeling and Experimental Studies

No abstract provided.

Cfd Optimized Woven Filter Media For Wastewater Application, Markus Knefel

Wastewater and Biosolids Treatment and Reuse: Bridging Modeling and Experimental Studies

No abstract provided.

Akabot: 3d Printing Filament Extruder, Emily Albi, Kevin Kozel, Daniel Ventoza, Rachel Wilmoth

Mechanical Engineering Senior Theses

3D printing could usher in a new age of localized manufacturing in places like Uganda, where three of our senior design team members spent the summer of 2013. Motivated by a concept for our senior design project, one of our team members interned with Village Energy, a small electronics business in Kampala, Uganda, as it piloted the use of a 3D printer to manufacture enclosures for its solar lights. The need for our project arose when we realized that although the 3D printer proved a viable method of manufacturing enclosures, Village Energy could not afford to continue 3D printing with …

Life Water, Colin Boyle, Scott Hanson

Civil, Environmental and Sustainable Engineering Senior Theses

A rainwater harvesting and treatment system was designed and constructed for the Hope for Life Ministry's home for street boys, located outside of Kigali, Rwanda. This system included two different components: a showering system and a potable system. The design and construction of the shower system utilized the roof space of the property's main building to capture water in two separate 10,000-liter tanks on either side of the building. Manual hand pumps were then installed in shower rooms located on either side of the building and were connected to the tanks with piping. 55-gallon barrels were placed in the shower …

Design Of A Low-Impact Wastewater Collection And Treatment System For Siladen Island In Indonesia, Kyle Astill, Charles Rymer, Joseph Sarmiento

Civil, Environmental and Sustainable Engineering Senior Theses

Untreated wastewater is highly destructive to human health and the environment. Choosing an island location, Pulau Siladen, which has no wastewater treatment solution, the design team embarked upon designing a centralized collection and treatment system to treat the island population's wastewater, in the interests of preserving human health and the sensitive coral reefs surrounding the island. This system features a gravity sewer system, flow equalization, sequencing batch reactor, sand filter and disinfection as part of the treatment process. This project will emphasize the reduction in use of highly specialized and manufactured components, in an effort to minimize the economic, environmental …

Pb: Project Battery - A Portable In-Home Power System, Devin Blaney, Brian Fahey, Amanda Tran

Electrical and Computer Engineering Senior Theses

Renewable energy resources are abundant in most developing countries. These sources include solar energy, wind power, geothermal energy, and biomass. Even though these sources are readily available, most villages in these developing countries do not have access to power in their homes because electricity grid extensions are often not affordable. This leaves the people in developing countries lacking resources that most of us take for granted here in the US. They don't have access to electrical power and light. This forces the people of these areas to use toxic kerosene lamps, which pollute the environment and increase health issues. This …

Improving The Complementary Methods To Estimate Evapotranspiration Under Diverse Climatic And Physical Conditions, Fathi Anayah, Jagath J. Kaluarachchi

Civil and Environmental Engineering Faculty Publications

Reliable estimation of evapotranspiration (ET) is important for the purpose of water resources planning and management. Complementary methods, including complementary relationship areal evapotranspiration (CRAE), advection aridity (AA) and Granger and Gray (GG), have been used to estimate ET because these methods are simple and practical in estimating regional ET using meteorological data only. However, prior studies have found limitations in these methods especially in contrasting climates. This study aims to develop a calibration-free universal method using the complementary relationships to compute regional ET in contrasting climatic and physical conditions with meteorological data only. The proposed methodology consists of a systematic …