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2012

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Full-Text Articles in Engineering

Achieving A Sustainable Environmental Perspective, Benjamin Linder Aug 2012

Achieving A Sustainable Environmental Perspective, Benjamin Linder

Benjamin Linder

The design profession is in a position to address the environmental challenges faced by society and progress is being made in this direction. However, this paper cautions that achieving a sustainable environmental perspective within design requires educators and practitioners to go beyond the specifics of materials, tools and common strategies and address the very status of the environmental perspective. They will have to elevate this perspective above others and shift it from a relative requirement to an absolute one. Doing so will require several fundamental changes to design education and practice.


A Physical Model For The Kink Effect In Inalas/Ingaas Hemt’S, Mark Somerville, Alexander Ernst, Jesus Del Alamo Jul 2012

A Physical Model For The Kink Effect In Inalas/Ingaas Hemt’S, Mark Somerville, Alexander Ernst, Jesus Del Alamo

Mark Somerville

We present a new model for the the kink effect in InAlAs/InGaAs HEMTs. The model suggests that the kink is due to a threshold voltage shift which arises from a hole pile-up in the extrinsic source and an ensuing charging ofthe surface and/or the buffer-substrate interface. The model captures many of the observed behaviors of the kink, including the kink's dependence on bias, time, temperature, illumination, and device structure. Using the model, we have developed a simple equivalent circuit, which reproduced well the kink's dc characteristics, its time evolution in the nanosecond range, and its dependence on illumination.


Degradation Uniformity Of Rf-Power Gaas Phemts Under Electrical Stress, Anita Villanueva, Jesus Del Alamo, Takayuki Hisaka, Kazuo Hayashi, Mark Somerville Jul 2012

Degradation Uniformity Of Rf-Power Gaas Phemts Under Electrical Stress, Anita Villanueva, Jesus Del Alamo, Takayuki Hisaka, Kazuo Hayashi, Mark Somerville

Mark Somerville

We have studied the electrical degradation of RF-power PHEMTs by means of in situ 2-D light-emission measurements. Electroluminescence originates in the recombination of holes that have been generated by impact ionization. The local light intensity, thus, maps the electric-field distribution at the drain side of the device. This allows us to probe the uniformity of electrical degradation due to electric-field-driven mechanisms. We find that electrical degradation proceeds in a highly nonuniform manner across the width of the device. In an initial phase, degradation takes place preferentially toward the center of the gate finger. In advanced stages of degradation, the edges …


Determining Dominant Breakdown Mechanisms In Inp Hemts, Mark Somerville, Chris Putnam, Jesus Del Alamo Jul 2012

Determining Dominant Breakdown Mechanisms In Inp Hemts, Mark Somerville, Chris Putnam, Jesus Del Alamo

Mark Somerville

We present a new technique for determining the dominant breakdown mechanism in InAlAs-InGaAs high-electron mobility transistors. By exploiting both the temperature dependence and the bias dependence of different physical mechanisms, we are able to discriminate impact ionization gate current from tunneling and thermionic field emission gate current in these devices. Our results suggest that the doping level of the supply layers plays a key role in determining the relative importance of these two effects.


Film Thickness Constraints For Manufacturable Strained Silicon Cmos, J. Fiorenza, G. Braithwaite, C. Leitz, M. Currie, J. Yap, F. Singaporewala, V. Yang, T. Langdo, J. Carlin, Mark Somerville, A. Lochtefeld, H. Badawi, M. Bulsara Jul 2012

Film Thickness Constraints For Manufacturable Strained Silicon Cmos, J. Fiorenza, G. Braithwaite, C. Leitz, M. Currie, J. Yap, F. Singaporewala, V. Yang, T. Langdo, J. Carlin, Mark Somerville, A. Lochtefeld, H. Badawi, M. Bulsara

Mark Somerville

This paper studies the effect of the strained silicon thickness on the characteristics of strained silicon MOSFETs on SiGe virtual substrates. NMOSFETs were fabricated on strained silicon substrates with various strained silicon thicknesses, both above and below the strained silicon critical thickness. The low field electron mobility and subthreshold characteristics of the devices were measured. Low field electron mobility is increased by about 1.8 times on all wafers and is not significantly degraded on any of the samples, even for a strained silicon thickness far greater than the critical thickness. From the subthreshold characteristics, however, it is shown that the …


Physical Mechanisms Limiting The Manufacturing Uniformity Of Millimeter-Wave Power Inp Hemt's, Sergei Krupenin, Roxann Blanchard, Mark Somerville, Jesus Del Alamo, K. Duh, Pane Chao Jul 2012

Physical Mechanisms Limiting The Manufacturing Uniformity Of Millimeter-Wave Power Inp Hemt's, Sergei Krupenin, Roxann Blanchard, Mark Somerville, Jesus Del Alamo, K. Duh, Pane Chao

Mark Somerville

We have developed a methodology to diagnose the physical mechanisms limiting the manufacturing uniformity of millimeter-wave power InAlAs/InGaAs HEMT's on InP. A statistical analysis was carried out on dc figures of merit obtained from a large number of actual devices on an experimental wafer. Correlation studies and principal component analysis of the results indicated that variations in Si delta-doping concentration introduced during molecular-beam epitaxy accounted for more than half of the manufacturing variance. Variations in the gate-source distance that is determined by the electron-beam alignment in the gate formation process were found to be the second leading source of manufacturing …


Strained Si On Insulator Technology: From Materials To Devices, T. Langdo, M. Currie, Z.-Y. Cheng, J. Fiorenza, M. Erdtmann, G. Braithwaite, C. Leitz, C. Vineis, J. Carlin, A. Lochtefeld, M. Bulsara, Isaac Lauer, Dimitri Antoniadis, Mark Somerville Jul 2012

Strained Si On Insulator Technology: From Materials To Devices, T. Langdo, M. Currie, Z.-Y. Cheng, J. Fiorenza, M. Erdtmann, G. Braithwaite, C. Leitz, C. Vineis, J. Carlin, A. Lochtefeld, M. Bulsara, Isaac Lauer, Dimitri Antoniadis, Mark Somerville

Mark Somerville

SiGe-free strained Si on insulator (SSOI) is a new material system that combines the carrier transport advantages of strained Si with the reduced capacitance and improved scalability of thin film silicon on insulator (SOI). We demonstrate fabrication of 20% Ge equivalent strain level SSOI substrates with Si thicknesses of 100 and 400 Å by hydrogen-induced layer transfer of strained Si layers from high quality graded SiGe virtual substrates. The substrate properties are excellent: wafer scale strained Si film thickness uniformities are better than 8%, strained Si surface roughnesses are better than 0.5 nm RMS, and robust tensile strain levels are …


Fully Depleted N-Mosfets On Supercritical Thickness Strained Soi, Isaac Lauer, T. Langdo, Z.-Y. Cheng, J. Fiorenza, G. Braithwaite, M. Currie, C. Leitz, A. Lochtefeld, H. Badawi, M. Bulsara, Mark Somerville, Dimitri Antoniadis Jul 2012

Fully Depleted N-Mosfets On Supercritical Thickness Strained Soi, Isaac Lauer, T. Langdo, Z.-Y. Cheng, J. Fiorenza, G. Braithwaite, M. Currie, C. Leitz, A. Lochtefeld, H. Badawi, M. Bulsara, Mark Somerville, Dimitri Antoniadis

Mark Somerville

Strained silicon-on-insulator (SSOI) is a new material system that combines the carrier transport advantages of strained Si with the reduced parasitic capacitance and improved MOSFET scalability of thin-film SOI. We demonstrate fabrication of highly uniform SiGe-free SSOI wafers with 20% Ge equivalent strain and report fully depleted n-MOSFET results. We show that enhanced mobility is maintained in strained Si films transferred directly to SiO2 from relaxed Si0.8Ge0.2 virtual substrates, even after a generous MOSFET fabrication thermal budget. Further, we find the usable strained-Si thickness of SSOI significantly exceeds the critical thickness of strained Si/SiGe without deleterious leakage current effects typically …


On An Orthogonal Space-Time-Polarization Block Code, Beata Wysocki, Tadeusz Wysocki, Sarah Adams Jul 2012

On An Orthogonal Space-Time-Polarization Block Code, Beata Wysocki, Tadeusz Wysocki, Sarah Adams

Sarah Spence Adams

Over the past several years, diversity methods such as space, time, and polarization diversity have been successfully implemented in wireless communications systems. Orthogonal space-time block codes efficiently combine space and time diversity, and they have been studied in detail. Polarization diversity has also been studied, however it is usually considered in a simple concatenation with other coding methods. In this paper, an efficient method for incorporating polarization diversity with space and time diversity is studied. The simple yet highly efficient technique is based on extending orthogonal space-time block codes into the quaternion domain and utilizing a description of the dual-polarized …


Novel Constructions Of Improved Square Complex Orthogonal Designs For Eight Transmit Antennas, Le Chung Tran, Tadeusz Wysocki, Jennifer Seberry, Alfred Mertins, Sarah Adams Jul 2012

Novel Constructions Of Improved Square Complex Orthogonal Designs For Eight Transmit Antennas, Le Chung Tran, Tadeusz Wysocki, Jennifer Seberry, Alfred Mertins, Sarah Adams

Sarah Spence Adams

Constructions of square, maximum rate complex orthogonal space-time block codes (CO STBCs) are well known, however codes constructed via the known methods include numerous zeros, which impede their practical implementation. By modifying the Williamson and Wallis-Whiteman arrays to apply to complex matrices, we propose two methods of construction of square, order-4n CO STBCs from square, order-n codes which satisfy certain properties. Applying the proposed methods, we construct square, maximum rate, order-8 CO STBCs with no zeros, such that the transmitted symbols are equally dispersed through transmit antennas. Those codes, referred to as the improved square CO STBCs, have the advantages …


An Extension Of The Channel-Assignment Problem: L(2, 1)-Labelings Of Generalized Petersen Graphs, Sarah Adams, Jonathan Cass, Denise Troxell Jul 2012

An Extension Of The Channel-Assignment Problem: L(2, 1)-Labelings Of Generalized Petersen Graphs, Sarah Adams, Jonathan Cass, Denise Troxell

Sarah Spence Adams

The channel-assignment problem involves assigning frequencies represented by nonnegative integers to radio transmitters such that transmitters in close proximity receive frequencies that are sufficiently far apart to avoid interference. In one of its variations, the problem is commonly quantified as follows: transmitters separated bythe smallest unit distance must be assigned frequencies that are at least two apart and transmitters separated by twice the smallest unit distance must be assigned frequencies that are at least one apart. Naturally, thischannel-assignment problem can be modeled with vertex labelings of graphs. An L(2, 1)-labeling of a graph G is a function f from the …


Quaternion Orthogonal Designs From Complex Companion Designs, Sarah Adams, Jennifer Seberry, Nathaniel Karst, Jonathan Pollack, Tadeusz Wysocki Jul 2012

Quaternion Orthogonal Designs From Complex Companion Designs, Sarah Adams, Jennifer Seberry, Nathaniel Karst, Jonathan Pollack, Tadeusz Wysocki

Sarah Spence Adams

The success of applying generalized complex orthogonal designs as space–time block codes recently motivated the definition of quaternion orthogonal designs as potential building blocks for space–time-polarization block codes. This paper offers techniques for constructing quaternion orthogonal designs via combinations of specially chosen complex orthogonal designs. One technique is used to build quaternion orthogonal designs on complex variables for any even number of columns. A second related technique is applied to maximum rate complex orthogonal designs to generate an infinite family of quaternion orthogonal designs on complex variables such that the resulting designs have no zero entries. This second technique is …


The Final Case Of The Decoding Delay Problem For Maximum Rate Complex Orthogonal Designs, Sarah Adams, Nathaniel Karst, Mathav Murugan Jul 2012

The Final Case Of The Decoding Delay Problem For Maximum Rate Complex Orthogonal Designs, Sarah Adams, Nathaniel Karst, Mathav Murugan

Sarah Spence Adams

Complex orthogonal space-time block codes (COSTBCs) based on generalized complex orthogonal designs (CODs) have been successfully implemented in wireless systems with multiple transmit antennas and single or multiple receive antennas. It has been shown that for a maximum rate COD with 2m-1 or 2m columns, a lower bound on decoding delay is (m-1 2m) and this delay is achievable when the number of columns is congruent to 0, 1 , or 3 modulo 4. In this paper, the final case is addressed, and it is shown that when the number of columns is congruent to 2 modulo 4, the lower …


Improving Endmilling Surface Finish By Workpiece Rotation And Adaptive Toolpath Spacing, Athulan Vijayaraghavan, Aaron Hoover, Jeffrey Hartnett, David Dornfeld Jul 2012

Improving Endmilling Surface Finish By Workpiece Rotation And Adaptive Toolpath Spacing, Athulan Vijayaraghavan, Aaron Hoover, Jeffrey Hartnett, David Dornfeld

Aaron M. Hoover

Free-form surfaces are being used in a growing number of engineering applications, especially in injection molding of consumer products. Decreasing the manufacturing cost and time of these molds will improve the efficiency of manufacturing injection molded consumer products. This paper is motivated by the need for simple strategies to improve the quality of and decrease the time required to machine free-form surfaces. We present two methods to improve the surface finish of parts finished with ball-nose endmilling. In the first method the surface finish is improved by finding an optimal orientation angle for the workpiece relative to the machining axis. …


Rapid Inversion: Running Animals And Robots Swing Like A Pendulum Under Ledges, Jean-Michel Mongeau, Brian Mcrae, Ardian Jusufi, Paul Birkmeyer, Aaron M. Hoover, Ronald Fearing, Robert J. Full Jul 2012

Rapid Inversion: Running Animals And Robots Swing Like A Pendulum Under Ledges, Jean-Michel Mongeau, Brian Mcrae, Ardian Jusufi, Paul Birkmeyer, Aaron M. Hoover, Ronald Fearing, Robert J. Full

Aaron M. Hoover

Escaping from predators often demands that animals rapidly negotiate complex environments. The smallest animals attain relatively fast speeds with high frequency leg cycling, wing flapping or body undulations, but absolute speeds are slow compared to larger animals. Instead, small animals benefit from the advantages of enhanced maneuverability in part due to scaling. Here, we report a novel behavior in small, legged runners that may facilitate their escape by disappearance from predators. We video recorded cockroaches and geckos rapidly running up an incline toward a ledge, digitized their motion and created a simple model to generalize the behavior. Both species ran …


Trajectory Generation In High-Speed, High-Precision Micromilling Using Subdivision Surfaces, Athulan Vijayaraghavan, Angela Sodemann, Aaron Hoover, J. Mayor, David Dornfeld Jul 2012

Trajectory Generation In High-Speed, High-Precision Micromilling Using Subdivision Surfaces, Athulan Vijayaraghavan, Angela Sodemann, Aaron Hoover, J. Mayor, David Dornfeld

Aaron M. Hoover

Motion control in high-speed micromilling processes requires fast, accurate following of a specified curvilinear path. The accuracy with which the path can be followed is determined by the speed at which individual trajectories can be generated and sent to the control system. The time required to generate the trajectory is dependent on the representations used for the curvilinear trajectory path. In this study, we introduce the use of subdivision curves as a method for generating high-speed micromilling trajectories. Subdivision curves are discretized curves which are specified as a series of recursive refinements of a coarse mesh. By applying these recursive …


An Autozeroing Floating-Gate Amplifier, Paul Hasler, Bradley Minch, Chris Diorio Jul 2012

An Autozeroing Floating-Gate Amplifier, Paul Hasler, Bradley Minch, Chris Diorio

Bradley Minch

We have developed a bandpass floating-gate amplifier that uses tunneling and pFET hot-electron injection to set its dc operating point adaptively. Because the hot-electron injection is an inherent part of the pFET's behavior, we obtain this adaptation with no additional circuitry. Because the gate currents are small, the circuit exhibits a high-pass characteristic with a cutoff frequency less than 1 Hz. The high-frequency cutoff is controlled electronically, as is done in continuous-time filters. We have derived analytical models that completely characterize the amplifier and that are in good agreement with experimental data for a wide range of operating conditions and …


Multiple-Input Translinear Element Networks, Bradley Minch, Paul Hasler, Chris Diorio Jul 2012

Multiple-Input Translinear Element Networks, Bradley Minch, Paul Hasler, Chris Diorio

Bradley Minch

We describe a new class of translinear circuits that accurately embody product-of-power-law relationships in the current signal domain. We call such circuits multiple-input translinear element (MITE) networks. A MITE is a circuit element, which we defined recently that produces an output current that is exponential in a weighted sum of its input voltages. We describe intuitively the basic operation of MITE networks and provide a systematic matrix technique for analyzing the nonlinear relationships implemented by any given circuit. We also show experimental data from three MITE networks that were fabricated in a 1.2-μm double-poly CMOS process.


Synthesis Of Static And Dynamic Multiple-Input Translinear Element Networks, Bradley Minch Jul 2012

Synthesis Of Static And Dynamic Multiple-Input Translinear Element Networks, Bradley Minch

Bradley Minch

In this paper, we discuss the process of synthesizing static and dynamic multiple-input translinear element (MITE) networks systematically from high-level descriptions given in the time domain, in terms of static polynomial constraints and algebraic differential equations. We provide several examples, illustrating the process for both static and dynamic system constraints. Although our examples will all involve MITE networks, the early steps of the synthesis process are equally applicable to the synthesis of static and dynamic translinear-loop circuits.


Integration Of Chemical Sensing And Electrowetting Actuation On Chemoreceptive Neuron Mos (Cνmos) Transistors, Nick Shen, Zengtao Liu, Blake Jacquot, Bradley Minch, Edwin Kan Jul 2012

Integration Of Chemical Sensing And Electrowetting Actuation On Chemoreceptive Neuron Mos (Cνmos) Transistors, Nick Shen, Zengtao Liu, Blake Jacquot, Bradley Minch, Edwin Kan

Bradley Minch

An integration of chemical sensors and electrowetting actuators based on the chemoreceptive neuron MOS (CνMOS) transistors has brought forth a novel system-on-chip approach to the microfluidic system. The extended floating-gate structure of the CνMOS transistors enables monolithic sensing and actuating schemes. The sensors with generic chemical receptive areas have been characterized with various fluids, and have demonstrated a high sensitivity from the current differentiation and a large dynamic range from threshold-voltage shifts in sensing polar and electrolytic liquids. The actuators have illustrated valve functions based on contact-angle modification by nonvolatile charge injection into the channel wall. Electrochemical models for sensing …


A Second-Order Section Built From Autozeroing Floating-Gate Amplifiers, Paul Hasler, Theron Stanford, Bradley Minch Jul 2012

A Second-Order Section Built From Autozeroing Floating-Gate Amplifiers, Paul Hasler, Theron Stanford, Bradley Minch

Bradley Minch

We introduce the autozeroing floating-gate (AFGA) secondorder section. We built this second-order filter where the corner frequency and Q are electronically tunable based on a classic filter topology and principles of operational transconductance amplifiers. We built this second order filter using three AFGAs—our floating-gate amplifier that sets its operating point by the interaction of hot-electron injection and electron tunneling.


Hysteretic Threshold Logic And Quasi-Delay Insensitive Asynchronous Design, Mark Neidengard, Bradley Minch Jul 2012

Hysteretic Threshold Logic And Quasi-Delay Insensitive Asynchronous Design, Mark Neidengard, Bradley Minch

Bradley Minch

We introduce the class of hysteretic linear-threshold (HLT) logic functions as a novel extension of linear threshold logic, and prove their general applicability for constructing state-holding Boolean functions. We then demonstrate a fusion of HLT logic with the quasi-delay insensitive style of asynchronous circuit design, complete with logical design examples. Future research directions are also identified.


A Physical Compact Model Of Dg Mosfet For Mixed-Signal Circuit Applications - Part I: Model Description, Gen Pei, Weiping Ni, Abhishek Kammula, Bradley Minch, Edwin Kan Jul 2012

A Physical Compact Model Of Dg Mosfet For Mixed-Signal Circuit Applications - Part I: Model Description, Gen Pei, Weiping Ni, Abhishek Kammula, Bradley Minch, Edwin Kan

Bradley Minch

To use double-gate (DG) MOSFET for mixed-signal circuit applications, especially for circuits in which the two gates are independently driven, such as in the case of dynamic-threshold and fixed-potential-plane operations, physical compact models that are valid for all modes of operations are necessary for accurate design and analysis. Employing physically rigorous current-voltage (I-V) relationship in subthreshold and above-threshold regions as asymptotic cases, we have constructed a model that joins the two operating regions by using carrier-screening functions. We have included consistently source/drain series resistance, low drain-field mobility, and small-geometry effects of drain-induced barrier lowering (DIBL), MOS interface mobility, velocity saturation …


Charge-Based Chemical Sensors: A Neuromorphic Approach With Chemoreceptive Neuron Mos (Cvmos) Transistors, Nick Shen, Zengtao Liu, Chungho Lee, Bradley Minch, Edwin Kan Jul 2012

Charge-Based Chemical Sensors: A Neuromorphic Approach With Chemoreceptive Neuron Mos (Cvmos) Transistors, Nick Shen, Zengtao Liu, Chungho Lee, Bradley Minch, Edwin Kan

Bradley Minch

A novel chemoreceptive neuron MOS (CνMOS) transistor with an extended floating-gate structure has been designed with several individual features that significantly facilitate system integration of chemical sensing. We have fabricated CνMOS transistors with generic molecular receptive areas and have characterized them with various fluids. We use an insulating polymer layer to provide physical and electrical isolation for sample fluid delivery. Experimental results from these devices have demonstrated both high sensitivity via current differentiation and large dynamic range from threshold voltage shifts in sensing both polar and electrolytic liquids. We have established electrochemical models for both steady-state and transient analyses. Our …


Silicon Synaptic Adaptation Mechanisms For Homeostasis And Contrast Gain Control, Shih-Chii Liu, Bradley Minch Jul 2012

Silicon Synaptic Adaptation Mechanisms For Homeostasis And Contrast Gain Control, Shih-Chii Liu, Bradley Minch

Bradley Minch

We explore homeostasis in a silicon integrate-and-fire neuron. The neuron adapts its firing rate over time periods on the order of seconds or minutes so that it returns to its spontaneous firing rate after a sustained perturbation. Homeostasis is implemented via two schemes. One scheme looks at the presynaptic activity and adapts the synaptic weight depending on the presynaptic spiking rate. The second scheme adapts the synaptic"threshold" depending on the neuron's activity. The threshold is lowered if the neuron's activity decreases over a long time and is increased for prolonged increase in postsynaptic activity. The presynaptic adaptation mechanism models the …


Construction And Transformation Of Multiple-Input Translinear Element Networks, Bradley Minch Jul 2012

Construction And Transformation Of Multiple-Input Translinear Element Networks, Bradley Minch

Bradley Minch

We present a simple algorithmic procedure for constructing a multiple-input translinear element (MITE) network from a translinear-loop equation. We also give a number of MITE-network transformations that alter the structure of the MITE network without altering the translinear-loop equation that it embodies. The results that we establish in this paper serve as foundations for the synthesis of both static and dynamic MITE networks from high-level specifications.


Effect Of Applied Uniaxial Stress On Rate And Mechanical Effects Of Cross-Linking In Tissue-Derived Biomaterials, Debbie Chachra, Paul Gratzer, Christopher Pereira, J. Lee Jul 2012

Effect Of Applied Uniaxial Stress On Rate And Mechanical Effects Of Cross-Linking In Tissue-Derived Biomaterials, Debbie Chachra, Paul Gratzer, Christopher Pereira, J. Lee

Debbie Chachra

Conformational changes in collagen fibrils, and indeed the triple helix, can be produced by application of mechanical stress or strain. We have demonstrated that the rate of cross-linking in glutaraldehyde and epoxide homobifunctional reagents can be modulated by uniaxial stress (strain). Two poly(glycidyl ether) epoxides were used: Denacol® EX-810 (a small bifunctional reagent), and Denacol EX-512 (a large polyfunctional reagent). To prevent any possible effect from being masked by saturation of cross-linking sites, bovine pericardium was cross-linked to such an extent that the increase in collagen denaturation temperature, Td, was one-half of the maximal rise achievable with …


Shelf-Life Of Bioprosthetic Heart Valves: A Structural And Mechanical Study, Maryse Julien, Dany Letouneau, Yves Marois, Alain Cardou, Martin King, Robert Guidoin, Debbie Chachra, J. Lee Jul 2012

Shelf-Life Of Bioprosthetic Heart Valves: A Structural And Mechanical Study, Maryse Julien, Dany Letouneau, Yves Marois, Alain Cardou, Martin King, Robert Guidoin, Debbie Chachra, J. Lee

Debbie Chachra

This study was undertaken to evaluate the influence of storage conditions on the shelf-life of porcine bioprosthetic valves. Fifty-five unimplanted porcine bioprostheses have been evaluated. The valves were stored in 0.5% buffered glutaraldehyde solution for different periods of time (7, 23 and 32 months). Twenty-eight valves were refrigerated while the remaining valves were stored at room temperature. The pH of the glutaraldehyde solution at room temperature decreased with time of storage, while that kept in the refrigerator remained stable over the course of the study. Macroscopic observations showed that the valve tissues kept at room temperature, especially for the periods …


Beyond Course-Based Engineering Ethics Instruction Commentary On “Topics And Cases For Online Education In Engineering”, Debbie Chachra Jul 2012

Beyond Course-Based Engineering Ethics Instruction Commentary On “Topics And Cases For Online Education In Engineering”, Debbie Chachra

Debbie Chachra

Discusses how online forums and materials could be used to enhance face-to-face courses in engineering and science ethics.


Lumbar Vertebral Density And Mechanical Properties In Aged Ovariectomized Rats Treated With Estrogen And Norethindrone Or Norgestimate, Carla Vanin, Neil Maclusky, Debbie Chachra, Mehran Kasra, Marc Grynpas, Robert Casper Jul 2012

Lumbar Vertebral Density And Mechanical Properties In Aged Ovariectomized Rats Treated With Estrogen And Norethindrone Or Norgestimate, Carla Vanin, Neil Maclusky, Debbie Chachra, Mehran Kasra, Marc Grynpas, Robert Casper

Debbie Chachra

OBJECTIVE: This study was designed to investigate the effects of estrogen alone or combined with two different progestins, norethindrone or norgestimate, on bone density and compressive mechanical properties in an aged rat model.

STUDY DESIGN: Twenty 11-month-old female Sprague-Dawley rats were sham operated (intact control) and 80 wee overiectomized. Three groups of 20 ovariectomized rats were implanted with Silastic silicon rubber (Dow Corning, Midland, Mich.) capsules containing 5% estradiol (wt/wt) in cholesterol. All rats in the intact control (group 1) and the ovariectomized (group 2) and the first of the overiectomized plus estrogen (group 3) groups were injected subcutaneously daily …