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Full-Text Articles in Engineering
The Economics Of Classroom 3-D Printing Of Open-Source Digital Designs Of Learning Aids, Nicole Gallup, Joshua M. Pearce
The Economics Of Classroom 3-D Printing Of Open-Source Digital Designs Of Learning Aids, Nicole Gallup, Joshua M. Pearce
Michigan Tech Publications
While schools struggle financially, capital for purchasing physical learning aids is often cut. To determine if costs could be reduced for learning aids, this study analyzed classroom-based distributed digital manufacturing using 3-D printing of open-source learning aid designs. Learning aid designs are analyzed in detail for their economic viability considering printing and assembly costs with purchased components and compared to equivalent or inferior commercial products available on Amazon. The results show current open-source 3-D printers are capable of manufacturing useful learning aids and that doing so provides high economic savings in the classroom. Overall, the average learning aid would save …
Tra-1-60-Positive/Cd45low Cells Found In The Peripheral Blood Of Prostate Cancer Patients With Metastatic Disease – A Proof-Of-Concept Study, Claudia Schäfer, Yawen Ju, Youngbin Tak, Cesar Vazquez, Sangyoon J. Han, Edwin Tan, Et Al.
Tra-1-60-Positive/Cd45low Cells Found In The Peripheral Blood Of Prostate Cancer Patients With Metastatic Disease – A Proof-Of-Concept Study, Claudia Schäfer, Yawen Ju, Youngbin Tak, Cesar Vazquez, Sangyoon J. Han, Edwin Tan, Et Al.
Michigan Tech Publications
Purpose
Over 90% of all cancer related deaths are due to metastasis. However, current diagnostic tools can't reliably discriminate between invasive and localized cancers.
Patients and methods
In this proof-of-concept study, we employed the embryonic stem cell marker TRA-1-60 (TRA+) to identify TRA + cells within the blood of prostate cancer patients and searched for TRA + cells in men with metastatic and localized cancers. We isolated whole peripheral blood mononuclear cells from 26 metastatic prostate cancer patients, from 13 patients with localized prostate cancer and from 17 healthy controls. Cells were stained for DAPI, CD45 and TRA + by …