Engineering Commons^™

Composition-Structure-Property Relationships In Multicomponent Bioactive Glasses, Sharon Murphy

Theses

Silicate glasses function effectively as bone grafts by stimulating bone regeneration through gene activation. However these materials offer little therapeutic potential for the regeneration of healthy bone in those suffering from metabolic bone diseases such as osteoporosis. Examining the composition-structure-property relationships arising from the incorporation of therapeutic ions such as strontium (Sr) and zinc (Zn) into such glasses in order to allow for healthy bone regeneration and antibacterial efficacy, as well as sodium (Na) to allow for controlled ion release was the objective of this work. Eight calcium-strontium-sodium-zinc-silicate glass compositions were produced, based on incremental additions of Sr and Na. …

Safety Data Dissemination Framework For Vehicular Networks, Martin Koubek

Theses

An effective transportation system is essential to modern societies with transportation having a significant influence on economic growth, social development and the environment. But this dependence on road mobility has had serious consequences in terms of rising crash costs that include deaths, injuries, lost productivity, material damage and congestion. The European Union and many other governments worldwide support active safety as being the next logical step in diminishing crash costs after passive safety (safety belt, ABS etc.) where drivers will be warned prior to reaching hazardous situations enabling them to react appropriately. While improving road safety is unanimously considered the …

Enhanced Vacuum Drying Through Improved Solvent Recovery, Reduced Process Cycle Times And Prediction Of Drying Duration, Diana Patricia Mesa Delgado

Theses

Drying of pharmaceuticals and fine chemicals is often accomplished under vacuum conditions to enhance energy efficiency and to avoid overheating of thermo sensitive materials. This project aims to study vacuum drying operations to obtain a better understanding of this process so as to optimize drying performance. This project obtained industrial data collected from a range companies in Ireland.

Pharmaceutical companies started assessing processes and making changes to drying processes from 2004 onwards; these initiatives are due to economic pressures, environmental issues and the Process Analytical Technology (PAT) initiative launched by the FDA in 2004.

Vacuum drying has been used in …

Performance Of Reinforced Concrete Columns Strengthened With Fiber Reinforced Polymers Under Various Loading Conditions, Mohamed Gamal Mohamed El Sayed

Theses

Strengthening of reinforced concrete (RC) structures with Carbon Fiber Reinforced Polymer (CFRP) composites has been a popular subject that attracted considerable attention from researchers for the last two decades. The high specific strength, stiffness, environmental resistance, and ease of application make CFRP composites highly desirable for strengthening and rehabilitation of RC structural components.

For concentrically loaded RC members with a circular cross-section, the lateral CFRP-confinement of concrete results in a substantial increase in load capacity and ductility. CFRP-confinement is less effective for RC compression members with square and rectangular cross-sections due to stress concentration at the corners and lack of …

Fabrication Of Polymeric Hollow Fiber Membrane For The Production Of Safe Drinking Water, Latifa Obeid Hamad Al-Nuaimi

Theses

Production of safe drinking water by using micro-filtration and ultra-filtration technologies has become more interesting. Water purification or filtration by using membrane began attracting much attention worldwide, because of its good characteristics such as: high efficiency in removing solid particles, viruses and germs and their low cost. This new technology is useful in industrial water treatment. The current studies in this field of polymer membrane manufacturing try to improve the characteristics, water flow rater and remove unwanted particles from water.

The recent project’s aim is to manufacture cellulose acetate hollow fibers. They were prepared by the Non Solvent Induced Phase …

Development Of A Toolbox For The Kinematic Evaluation Of Hands-Up Video Games, Brooke Marie Odle

Theses

Children with cerebral palsy (CP) often have limited upper extremity (UE) control, Virtual reality (VR) is a current technology being evaluated as a form of UE therapy for children with CP, The systems currently available have been developed with games that cannot be graded to match the skill level of children with severely impaired UE control. A novel video game platform, "Hands-Up", has been developed at New Jersey Institute of Technology. The platform features software that allows for the customization of games and encourages users to make purposeful UE movements. To quantify changes and improvement in movement due to increased …

Water Purification In Haiti : An Engineers Without Borders Project, Melissa Valoura

Theses

The objective of this thesis was to present the necessary steps to help a town in Haiti develop an organization focused on improving their water quality. It goes through the technology needed to create the organization and explains the procedures for implementing a charitable project in a foreign country. A narrative of the student project in Milot, Haiti, where students from the New Jersey Institute of Technology's Engineers Without Borders Chapter implemented a water purification project, explains the course of action that was taken and gives an example of a successful project. A summary of Haiti and its history paints …

Non-Foster Matching Of An Rfid Antenna, Nedime Pelin Yalcin

Theses

In this thesis, novel designs of radio-frequency identification (RFID) tag antennas with better matching characteristics to achieve extended range for passive tags have been investigated in the ultra-high frequency (UHF) band. A variety of cavitybacked/coupled microstrip dipole antennas in 915 MHz range were considered. Additionally, a negative impedance converter designed to cancel out antenna's input capacitance at resonance frequency and to produce the real antenna input impedance was designed, simulated and implemented for an RFID antenna. Numerical simulations have been carried out using ORCAD software package (Cadence), ADS software package (Agilent) and HFSS software package (ANSYS/ANSOFT Inc). Antennas have been …

Stress Corrosion Cracking Of Stainless Steels Used In Manufacturing Brine Circulating Pumps Used In Desalination Plants., Ahmed Ibrahim Ahmed Al-Joboury

Theses

In earlier works, characterization and stress corrosion cracking of casings of brine recirculation pumps used in desalination plants was investigated. These casings, which were manufactured from two types of Ni resist ductile irons, were reported to show different service lives. Material selection of casings is believed to be one of possible factors to extend the service lives of these pumps. Two types of stainless steels; UNS S31603 and UNS S32750 were recommended as substitutes to Ni resist ductile irons. In this work, mechanical, metallurgical, electrochemical and stress corrosion cracking (SCC) tests were conducted on as received samples, made from these …

Evaluation Of The Effectiveness Of Speed Cameras On Road Safety In The Emirate Of Abu Dhabi Roads, Ali Humaid Ai Darei

Theses

The problem of road safety in the Emirate of Abu Dhabi is eminent. According road crash data from the Ministry of Interior, from 1999 to 2007 the average percentage of deaths due to road crashes in the Emirate of Abu Dhabi was 42 percent of the whole UAE. The high death rate due to road crashes has enormous economic and financial loss to the Emirate. The previous research on road safety in the UAE reported that the aberrant driving behavior is one of the major causes for road crashes in the UAE. The aberrant driving behavior includes careless driving, speeding, …

Mixing Performance Of A Novel, Continuous Confined Impinging Jets Mixer Using Competitive Reactions, Han Zheng

Theses

In this work, a novel continuous flow apparatus featuring the impingement of fluid jet streams in the presence of ultrasonic energy provided by an ultrasonic probe was tested using competitive reactions in order to determine its mixing effectiveness. The ultrasonic energy enhances micromixing of the fluid jet streams, which results in an overall mixing effectiveness improvements in different physical and chemical processes.

In the competitive reactions system used here (third Bourne reaction), one stream containing sodium hydroxide was continuously fed to the first impinging jet, while an aqueous solution of hydrochloric acid and ethyl chloroacetate was fed to the second …

In Vitro Comparison Of A New Stand-Alone Anterior Lumbar Interbody Cage Device With Established Fixation Techniques, Nitin Chawla

Theses

Around 70% of the population in the United States experience low back pain at some point of their lives, of these 4% underwent surgical intervention on the lumbar spine to relieve the pain. Spinal arthrodesis, i.e. joint fusion, is beneficial in many cases as the final option for patients suffering from certain types of low back pain (LBP). In order to promote solid fusion across a decompressed spinal segment, interbody spacers/cages are used with and without posterior instrumentation to provide an initial "rigid" fixation of the segment.

In this study three fresh/frozen human cadaveric lumbar spines were used. Each lumbar …

Experimental Investigation Of Mixing Time In A Stirred, Torispherical-Bottomed Tank Equipped With A Retreat-Blade Impeller, Nonjaros Chomcharn

Theses

Glass-lined reactors are typically used in the pharmaceutical and specialty chemicals industries because of their material compatibility with most reactants and their cleanability. These reactors are typically equipped with a retreat-blade impeller placed close to the bottom of the tank a single baffle mounted from the top. The mixing performance of such reactors has not received significant attention in the literature, despite their ubiquitous presence in the pharmaceutical industry. In particular, mixing time, i.e., the time required by the system to achieve a predefined level of homogeneity, has not been studied to any significant degree.

In this work, the mixing …

Reliability Of Resting Brain Networks Using Fmri, Suril Rajeshkumar Gohel

Theses

Resting state FMRI studies on human subjects are primarily focused on elaborating effects of resting state brain networks on task induced paradigm and to check consistency of these networks between different groups of populations. Recent studies have shown consistency of RSFC networks within same subjects with intra-site and intra-session variation.

The primary objective of this study was to check consistency of resting state networks between sites and between different groups of people in spite of change in scanning parameters and population. A total of 437 subjects resting state FMRI data from six different sites were collected varying in age group …

An In Vitro Study To Characterize A New Automated High Throughput Neuronal Stretch Injury System, Nicolae Valerian Hususan

Theses

Traumatic brain injury (TBI) is one of the most prevalent long-term neurological conditions and its overall economic consequences rival that of stroke. Considering the importance of the topic, new models for studying TBI are often designed and created. Based on a model developed by the University of Pennsylvania, NJIT constructed a fully automated version, which injures neuronal cell cultures in uniaxial regime and provides the high experimental yield required in pharmaceutical and neuroscience studies.

In this investigation, a new methodology for culturing primary cortical neurons of rat origin was established. Viable cell cultures developed for the first time in NJIT …

Development Of An Experimental System To Determine The Contribution Of Titin And Collagen To Passive Stiffness Of Myocardium, Saurin Bharat Shah

Theses

Diastolic dysfunction is known to be a major factor for congestive heart failure in aged humans and other mammals. The main contributors to increase in the myocardial stiffness, hindering the cardiac mechanics, are alterations in intracellular titin and extracellular collagen matrix. Titin is a giant extensible protein, the third filament of striated muscle after actin and myosin, which provides elasticity to passive sarcomeres. The aim of this study is to develop an efficient experimental system that will prove to be instrumental in comparing the contribution of titin against collagen to the passive stiffness of cardiac muscle extracted from experimental animals …

Evaluation Of Medical Alarm Sounds, Elizbha Philip

Theses

Auditory alarms in medical equipments perform considerably below their optimal level. Concern has been expressed about the quality of medical alarms by a large number of researchers in recent years. A detailed literature survey on the medical alarm related problems has been carried out. Hospital visits were made to obtain real life information and data of alarm sounds in various type of monitors used in OR and ICU. A laboratory experiment has been conducted on selected melodic alarm sounds. These melodic alarm sounds are being implemented in medical equipments and the idea of design is proposed in ISO / IEC …

Aptamer-Based Nano-Scale Dielectric Sensor For Protein Detection, Teena James

Theses

The specific detection and precise quantification of protein molecules play an essential role in basic discovery research as well as in clinical practice. In this research work, a novel protein detection mechanism based on nanoscale dielectric sensor functionalized with aptamer probes is developed. This work has been done in collaboration with Rational Affinity Devices LLC. The use of aptamer based detection offers several advantages over the traditional labor intensive antibody based immunosensing. In the initial phase of the work, the binding affinities of rationally designed oligomers towards a specific protein molecule (IgG) was studied and optimized under varying conditions of …

Preparation Of Nanovehicles For Targeted Drug Delivery, Anagha Avinash Bhakay

Theses

Application of nanotechnology in pharmaceutical research has opened new frontiers for drug development and its efficient delivery. In recent years, the focus of the research has been on the engineering of nano/micro-particulate structures for efficient and targeted delivery of drugs for selective and enhanced absorption. This work throws light on the preparation of biodegradable and non-toxic nanoparticulate systems for targeted drug delivery. The drug vehicles were made by two different processes namely electrostatic interactions and desolvation process. The drug carriers made by these processes were found to be in the size range of 150-200nm which is necessary for cellular uptake …

Deciphering The Biology Of Axon Stretch-Growth, Joseph R. Loverde

Theses

Traditional nerve regeneration strategies focus on growth cone-mediated growth, a form of nerve growth that occurs primarily during embryogenesis. Early axons continue to grow from the end distal to the soma, seeking targets on which to synapse. It is believed that once the axons synapse, stretch-growth takes over and is responsible for the great lengths achieved by nerves of the central and peripheral nervous systems. Recent work has demonstrated stretch-growth in vitro resulting in dramatically increased growth rates compared to the growth cone. Here, the aim was to decipher the underlying biology associated with axon stretch-growth using two approaches. First, …

Nano-Structured Platforms As A Spectroscopic Tool, Ruiqiong Li

Theses

Nano-structured platforms have been studied for the purpose of enhancing weak fluorescence signals. Each platform was constructed as a thin oxide layer on top of a metal (aluminum) The oxide was perforated with hexagonal array of nano-holes. The pitch of the array was much smaller than the optical wavelengths used. Surface charge waves (Surface Plasmons) could be excited when the platform was oriented at specific direction with respect to the incident optical beam. At this point one can demonstrate that fluorescence signals could be amplified. Since the oxide (alumina) is bio-compatible, one can envision using such platforms in the study …

Study And Development Of Ultrasound Monitoring Of Skeletal Defects, Kavil Patel

Theses

Fatigue fractures are fine disruptions of normal bone architecture whose identification is often unreliable or difficult using x-rays (Robinson, Wilson et al.; Kundel 2004; Swischuk and Hernandez 2004). A fatigue fracture results from the application of abnormal loads to a bone with normal elastic resistance and is associated with new or different activity, and strenuous or repeated activity. The feasibility of using ultrasound to detect and monitor fatigue fractures and other structural damage in bone was established in this study.

The use of Low Transient Pulse (LTP) technology to drive the ultrasound transducers proved to enhance detection resolution and quality …

Assessing Trainer Hand Forces For Manual Body Weight Supported Walking, Manish Raval

Theses

Spinal cord injuries occur in approximately 12,000 to 15,000 people per year in the U.S. About 10,000 of these people are permanently paralyzed. Most spinal cord traumas occur in young, healthy individuals. Males between 15 and 35 years old are most commonly affected.

Recently new approaches to facilitate walking recovery for individuals after a spinal cord injury, have been directed towards a therapy known as Locomotor Training (LT) that implements repetitive stepping on a treadmill using body weight support. A major intent of LT research is to investigate the effect of an extended period of LT on bilateral muscle activation …

Finger Walking Control Of A Two-Dimensional Walking Model Through Inverse Kinematics, Jordan Ratcliff

Theses

Those people who have spinal cord injuries (SCI) must remain in wheelchairs due to disruption of the neural signaling to their muscles. Functional electrical stimulation (FES) has proved itself to be an option for restoring some motion and some walking for the patient. Electrodes can either be placed on the skin or muscle to provide an electrical impulse that stimulates the muscles into contraction. Current systems provide buttons that use set functions for left and right steps with constant direction and size. It is desired however that the user be allowed a more natural and variable control method of controlling …

Dual Parametric Sensors For Highly Sensitive Nucleic Acid Detection, Manu Sebastian Mannoor

Theses

The primary focus of this research work was on the design and development of a molecular scale (nano-scale) capacitive sensing mechanism for the highly sensitive and label-free detection of Nucleic Acid hybridization. These novel capacitive sensors with nano-scale electrode spacing offer solutions to many problems suffered by the conventional signal transduction mechanisms, thereby immensely improving the sensitivity of the biomolecular detection processes. Reducing the separation between the capacitive electrodes to the same scale as the Debye length of the sample solution, results in the overlapping of the electrical double layers of the two electrodes, thereby confining them to occupy a …

Structural Behaviour And Analysis Of A Steel-Concrete Balcony Bracket, Sean Carroll

Theses

For commonly used moment connections, such as the various types of beam to column endplates, a large amount of information in relation to testing data and suggested design methods exist. Engineers can use this information to safely design such connections. When developing new and unique types of connections however, usually no prior testing information is available to engineers due to the unique design. At the present time, the most effective method of designing and developing any structural element or connection is through testing. Testing and detailed analysis of the results gives factual information on the behaviour of the structure, which …

The Development Of A Prototype Robotic Platform On Which Awareness Strategies Can Be Implemented, Sean Kinsella

Theses

This thesis describes the design and development of the hardware and software for a prototype robotic platform on which awareness strategies can be developed. The mobile prototype platform designed over the course of work is capable of operating as a distributed or centralised system.

There is no singular definition of awareness for a robotic system and the development of awareness strategies is complex and requires expertise in many scientific disciplines. This paper describes the different types of awareness associated with robotic systems and the technology required to implement this awareness. A review of sensors critical to the development of awareness …

Automated Network Planning For Industrial Ethernet Networks, Holger Machens

Theses

Engineers usually use computer aided methods to ease the increasingly complex planning task of automation plants. One such computer aided method for automated planning of Industrial Ethernet networks under given network QoS requirements is presented in this thesis. The method is based on partitioning the given set of network nodes according to specified communication relationships between the nodes, thereby creating subsets of nodes which are joined using given networking algorithms. Several networking algorithms may be applicable for each subset of nodes and any complete solution is a combination of several partial solutions, one for each subset of nodes. Enumeration through …

Optimisation Of Heat Sink Design, Kevin Moore

Theses

In the field of electronics cooling and more specifically processor cooling, the ability to cool a micro-chip is becoming a major issue. Power dissipation in home and office computers has risen from 30W to over 120W in the past 10 years, forcing heat sink designers to search for new ideas in the design of their heat spreaders.

This thesis studies in detail the fundamental technical designs used for modern day processor cooling. Using Computational Fluid Dynamics (CFD), various different pin/fin shapes were analysed to determine which yielded maximum heat transfer and contact area with forced air flow. Elliptical and teardrop …

A Middleware For True Mobile Agents In Wireless Sensor Networks, Ciarán Lynch

Theses

The application space of wireless sensor networks has evolved considerably from their initial role as an efficient data gathering system. Modern wireless sensor networks are expected to be dynamic, powerful. reliable and flexible, while continuing to operate efficiently and autonomously. The supporting software' systems have not kept pace with this development, and currently limits the deployment of complex and robust applications. Mobile software agents present a powerful approach to application design, however no existing middleware for wireless sensor networks supports native mobile software agents.

The main contribution of the work presented in this thesis is the development and evaluation of …