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Articles 151 - 180 of 3281
Full-Text Articles in Engineering
Predicting Sleep And Sleep Stage In Children Using Actigraphy And Heartrate Via A Long Short-Term Memory Deep Learning Algorithm: A Performance Evaluation, Robert Weaver Med, Phd, James White, Olivia Finnegan, Hongpeng Yang, Zifei Zhong, Keagan Kiely, Catherine Jones, Yan Tong, Srihari Nelakuditi, Rahul Ghosal, David E. Brown, Russell R. Pate Ph.D., Gregory J. Welk, Massimiliano De Zambotti, Yuan Wang, Sarah Burkart, Elizabeth L. Adams Phd, Bridget Armstrong, Michael Beets Med, Mph, Phd
Predicting Sleep And Sleep Stage In Children Using Actigraphy And Heartrate Via A Long Short-Term Memory Deep Learning Algorithm: A Performance Evaluation, Robert Weaver Med, Phd, James White, Olivia Finnegan, Hongpeng Yang, Zifei Zhong, Keagan Kiely, Catherine Jones, Yan Tong, Srihari Nelakuditi, Rahul Ghosal, David E. Brown, Russell R. Pate Ph.D., Gregory J. Welk, Massimiliano De Zambotti, Yuan Wang, Sarah Burkart, Elizabeth L. Adams Phd, Bridget Armstrong, Michael Beets Med, Mph, Phd
Faculty Publications
Children's ambulatory sleep is commonly measured via actigraphy. However, traditional actigraphy measured sleep (e.g., Sadeh algorithm) struggles to predict wake (i.e., specificity, values typically < 70) and cannot predict sleep stages. Long short-term memory (LSTM) is a machine learning algorithm that may address these deficiencies. This study evaluated the agreement of LSTM sleep estimates from actigraphy and heartrate (HR) data with polysomnography (PSG). Children (N = 238, 5–12 years,52.8% male, 50% Black 31.9% White) participated in an overnight laboratory polysomnography. Participants were referred be-cause of suspected sleep disruptions. Children wore an ActiGraph GT9X accelerometer and two of three consumer wearables(i.e., Apple Watch Series 7, Fitbit Sense, Garmin Vivoactive 4) on their non-dominant wrist during the polysomnogram. LSTM estimated sleep versus wake and sleep stage (wake, not-REM, REM) using raw actigraphy and HR data for each 30-s epoch. Logistic regression and random forest were also estimated as a benchmark for performance with which to compare the LSTM results. A 10-fold cross-validation technique was employed, and confusion matrices were constructed. Sensitivity and specificity were calculated to assess the agreement between research-grade and consumer wearables with the criterion polysomnography. For sleep versus wake classification, LSTM outperformed logistic regression and random forest with accuracy ranging from 94.1to 95.1, sensitivity ranging from 94.9 to 95.9 across different devices, and specificity ranging from 84.5 to 89.6. The addition of HR improved the prediction of sleep stages but not binary sleep versus wake. LSTM is promising for predicting sleep and sleep staging from actigraphy data, and HR may improve sleep stage prediction.
An Acoustofluidic Device For Sample Preparation And Detection Of Small Extracellular Vesicles, Jessica F. Liu, Jianping Xia, Joseph Rich, Shuaiguo Zhao, Kaichun Yang, Brandon Lu, Ying Chen, Tiffany Wen Ye, Tony Jun Huang
An Acoustofluidic Device For Sample Preparation And Detection Of Small Extracellular Vesicles, Jessica F. Liu, Jianping Xia, Joseph Rich, Shuaiguo Zhao, Kaichun Yang, Brandon Lu, Ying Chen, Tiffany Wen Ye, Tony Jun Huang
Faculty Publications
Small extracellular vesicles (sEVs) have emerged as powerful vectors for liquid biopsy, offering a noninvasive window into the dynamic physiological and pathological states of the body. However, to fully leverage the clinical potential of sEV biomarkers, it is imperative to develop robust and efficient technologies for their isolation and analysis. In this study, we introduce a novel sharp-edge acoustofluidic platform designed for rapid and effective sample preparation, coupled with sensitive detection of specific sEV populations based on their surface markers. Our approach utilizes acoustically activated sharp-edge microstructures to concentrate bead-bound sEVs within the microfluidic device, facilitating immediate visualization by fluorescence …
Machine Tool Interoperability In Smart Manufacturing And Industry 4.0, M. R. Mccormick, Mohammed Shafae, Thorsten Wuest
Machine Tool Interoperability In Smart Manufacturing And Industry 4.0, M. R. Mccormick, Mohammed Shafae, Thorsten Wuest
Faculty Publications
Real-time decision making is supported by data-hungry emerging technologies such as machine learning and digital twins. Innovations in manufacturing process control utilizing these technologies are constrained by interoperability. Marketing materials, sales pitches, and academic literature portray interoperability on the factory floor as seamless and robust. However, this study demonstrates that in spite of plentiful mature standards, interoperability on the factory floor is neither seamless nor robust. To exemplify interoperability in the context of an established and widely adopted standard, this study analyzes the interoperability of machine tools produced by a premier equipment builder which has exceeded US$1 billion in sales …
Enhancing Visibility On A Science Dmz With P4-Perfsonar, Ali Mazloum, Elie Kfoury, Ali Alsabeh, Jose Gomez, Jorge Crichigno
Enhancing Visibility On A Science Dmz With P4-Perfsonar, Ali Mazloum, Elie Kfoury, Ali Alsabeh, Jose Gomez, Jorge Crichigno
Faculty Publications
The Science Demilitarized Zone (Science DMZ) is a specialized network designed to facilitate the transfer of large-scale scientific data. One of the key elements of the Science DMZ is perfSONAR, an active performance measurement device that monitors end-to-end paths over multiple domains. Although versatile, perfSONAR faces limitations such as restricted visibility of events and coarse-grained measurements. This paper proposes a scheme that integrates P4 programmable data plane (PDP) switches with perfSONAR. P4 PDP switches are passively installed and operate on real-time traffic copies, providing flexibility to collect fine-grained custom measurements and report events in the data plane. This integration enables …
A Survey On Security Applications With Smartnics: Taxonomy, Implementations, Challenges, And Future Trends, Serigo Elizalde, Ali Alsabeh, Ali Mazloum, Samia Choeiri, Elie Kfoury, Jose Gomez, Jorge Crichigno
A Survey On Security Applications With Smartnics: Taxonomy, Implementations, Challenges, And Future Trends, Serigo Elizalde, Ali Alsabeh, Ali Mazloum, Samia Choeiri, Elie Kfoury, Jose Gomez, Jorge Crichigno
Faculty Publications
Over the last decade, network applications have grown exponentially, demanding high-speed interconnects. Unfortunately, chip manufacturers are approaching the upper limits of silicon-based computing with slow improvements in computational performance and energy efficiency. This trend has forced the industry to shift paradigms, moving from monolithic architectures to heterogeneous, domain-specific designs. Moreover, the ever-evolving threats compromise digital services and demand more scalable and flexible solutions to ensure service continuity in production networks. Smart Network Interface Cards (SmartNICs) are a product of this new paradigm, integrating domain-specific engines and general-purpose cores to offload various network infrastructure tasks, including those related to security. This …
Cell-Free Protein Synthesis Reactor Formats: A Brief History And Analysis, Dallin M. Chipman, Anna C. Woolley, Davu N. Chau, William A. Lance, Joseph P. Talley, Tyler P. Green, Benjamin C. Robbins, Bradley Charles Bundy
Cell-Free Protein Synthesis Reactor Formats: A Brief History And Analysis, Dallin M. Chipman, Anna C. Woolley, Davu N. Chau, William A. Lance, Joseph P. Talley, Tyler P. Green, Benjamin C. Robbins, Bradley Charles Bundy
Faculty Publications
Cell-free protein synthesis (CFPS) has transformed protein production capabilities by eliminating cellular constraints, enabling the rapid expression of difficult-to-produce proteins in an open, customizable environment. As CFPS applications expand from fundamental research to industrial production, therapeutic manufacturing, and point-of-care diagnostics, the diverse array of reactor formats has become increasingly important yet challenging to navigate. This review examines the evolution and characteristics of thirteen major CFPS reactor formats, from traditional batch systems to advanced platforms. The historical development of CFPS reactors from the 1960s to present day is presented. Additionally, for each format, operational principles, advantages, limitations, and notable applications are …
Numerical Simulation For The Design Of Induction Heating Based Radio Frequency Reactor For Ethylene Production, Hunter Teel, Matthew Craps, Hector-Colon Mercado, Perter Ciesielski, Sirivatch Shimpalee
Numerical Simulation For The Design Of Induction Heating Based Radio Frequency Reactor For Ethylene Production, Hunter Teel, Matthew Craps, Hector-Colon Mercado, Perter Ciesielski, Sirivatch Shimpalee
Faculty Publications
Ethylene is a vital petrochemical compound produced in vast amounts yearly by manufacturers that have enough scale to overcome the inherent thermodynamic inefficiencies of the process. In order to address the inefficiencies that prevent smaller scale or intermittent production ethylene, investigation of new production methods are required. In this work, we investigate the use of a radio frequency (RF) based reactor system that generates heat internally as opposed to applying heat externally via steam or direct combustion of fossil fuels. In order to guide the design of an electromagnetic based reactor system, we have created a macroscale model capable of …
A Comparative Techno-Economic Analysis Of Aqueous And Anhydrous Hcl Electrolysis Processes, O. Felix, K. Likit-Anurak, K. Ngamsanroaj, Sirivatch Shimpalee, Ben Meekins
A Comparative Techno-Economic Analysis Of Aqueous And Anhydrous Hcl Electrolysis Processes, O. Felix, K. Likit-Anurak, K. Ngamsanroaj, Sirivatch Shimpalee, Ben Meekins
Faculty Publications
The state-of-the-art aqueous HCl electrolysis process is a well-established process for chlorine production but faces challenges such as limited conversion efficiencies, corrosion, and additional pre- and post-electrolyzer processing steps that add to its cost. This study evaluates whether a recently demonstrated anhydrous HCl electrolysis process is more economically viable than the state-of-the-art aqueous process. A 1D electrolyzer model was developed using Aspen Custom Modeler® and integrated into Aspen Plus® for process modeling. Multiple conversion efficiencies (30.5 %, 50 %, 80 %, and 93.4 %) were analyzed for the anhydrous process, with various heat recovery and heat exchanger configurations assessed using …
Redundant Functions Of Mir156-Targeted Squamosa Promoter Binding Protein-Like Transcription Factors In Promoting Cauline Leaf Identity, Darren Manuela, Liren Du, Qi Zhang, Yifei Liao, Tieqiang Hu, Jim P. Fouracre, Mingli Xu
Redundant Functions Of Mir156-Targeted Squamosa Promoter Binding Protein-Like Transcription Factors In Promoting Cauline Leaf Identity, Darren Manuela, Liren Du, Qi Zhang, Yifei Liao, Tieqiang Hu, Jim P. Fouracre, Mingli Xu
Faculty Publications
No abstract provided.
Identification Of Authentic Gnss Signals In Time-Differenced Carrier-Phase Measurements With A Software-Defined Radio Receiver, Zhen Zhu, Sanjeev Gunawardena, Eric Vinande, Jason Pontious
Identification Of Authentic Gnss Signals In Time-Differenced Carrier-Phase Measurements With A Software-Defined Radio Receiver, Zhen Zhu, Sanjeev Gunawardena, Eric Vinande, Jason Pontious
Faculty Publications
The time-differenced carrier phase can be computed from measurements recorded by a multi-global navigation satellite system software-defined radio receiver such as PyChips, from which the user displacement and receiver clock drift can be solved. PyChips is able to simultaneously track authentic and inauthentic signals in separate channels, which makes it possible to observe both types of measurements with corresponding navigation data. A random sample consensus algorithm has been introduced to assess the consistency between the measurements and data. This algorithm successfully separated authentic channels from inauthentic channels when they are broadcast simultaneously.
Feedback Parameters For A Closed-Loop Multiple-Input Multiple-Output Model Of The Upper Limb, Ian Syndergaard, Daniel B. Free, Dario Farina, Steven Knight Charles
Feedback Parameters For A Closed-Loop Multiple-Input Multiple-Output Model Of The Upper Limb, Ian Syndergaard, Daniel B. Free, Dario Farina, Steven Knight Charles
Faculty Publications
Both closed-loop models and multi-input multi-output (MIMO) models of the neuromusculoskeletal system of the upper limb are important for simulating and understanding motor control. Yet no large-scale linear neuromusculoskeletal models of the upper limb that are both closed-loop and MIMO have been developed. The primary difficulty in creating such models is choosing appropriate feedback parameters (such as feedback gains and delays), as such a collection of parameters is not available in the literature. The purpose of this work is to 1) present a method for developing MIMO models of short-loop afferent feedback and 2) offer estimates of average feedback parameter …
High-Frequency Impedance Spectroscopy: Measurement Reproducibility, Electromagnetic, And Ionic Effects In Cylindrical Lithium-Ion Cells, Matthew R. King, Paul T. Coman, Rafid Mollah, Md Rayhan Khan, Saranraj Karuppuswami, Taylor R. Garrick, Ralph E. White
High-Frequency Impedance Spectroscopy: Measurement Reproducibility, Electromagnetic, And Ionic Effects In Cylindrical Lithium-Ion Cells, Matthew R. King, Paul T. Coman, Rafid Mollah, Md Rayhan Khan, Saranraj Karuppuswami, Taylor R. Garrick, Ralph E. White
Faculty Publications
Accurate high-frequency electrochemical impedance spectroscopy (HF EIS) is critical for understanding lithium-ion battery (LIB) behavior under AC perturbations, relevant to electric vehicle systems and charging infrastructure. However, measurements at high frequencies are often distorted by external electromagnetic interference, poor contact quality, and wiring artifacts. This study investigates four experimental testbench configurations for HF EIS of cylindrical LIBs, highlighting the impact of contact resistance, Faraday shielding, wire twisting, and calibration. A coupled electrochemical-electromagnetic model is developed to isolate and analyze the skin effect and frequency-dependent electrolyte conductivity. Results show that spot-welded connections, twisted and shielded wiring, and calibration within a Faraday …
3d Nano-Architected Polymer Shell Enables Reconfigurable Stabilized Blue Phase Soft Crystals, Sephideh Norouzi, Yazael R. Morales-Flores, Tadej Emersic, Jeremy Money, Otillo E. Rodriguez-Lopez, Andrew Casale, Juan J. De Pablo, Jose A. Martinez-Gonzalez, Monirosadat Sadati
3d Nano-Architected Polymer Shell Enables Reconfigurable Stabilized Blue Phase Soft Crystals, Sephideh Norouzi, Yazael R. Morales-Flores, Tadej Emersic, Jeremy Money, Otillo E. Rodriguez-Lopez, Andrew Casale, Juan J. De Pablo, Jose A. Martinez-Gonzalez, Monirosadat Sadati
Faculty Publications
Blue phases (BPs), formed through the self-assembly of chiral liquid crystal molecules into 3D nanolattices with cubic symmetries, exhibit dynamic photonic bandgaps in the visible spectrum, offering transformative opportunities for advanced optical circuits, sensing and communication technologies. However, their thermal stability is restricted to a narrow temperature range (0.5–1.0 K), limiting practical applications. Polymer stabilization of bulk BPs has extended thermal stability but often compromises the dynamic behavior essential for fast-response functionalities. Here, experimental and computational approaches are integrated to investigate the effect of curvature and interfacial interactions on BP polymer stabilization. It is demonstrated that photo-polymerization of reactive monomers …
High Field Performance Of Si-Doped N-Aln Layers Grown Using Pulsed Mocvd, Abdullah Al Mamun Mazumder, Tariq Jamil, Mafruda Rahman, Muhammad Ali, Grigory Simin, Asif Khan
High Field Performance Of Si-Doped N-Aln Layers Grown Using Pulsed Mocvd, Abdullah Al Mamun Mazumder, Tariq Jamil, Mafruda Rahman, Muhammad Ali, Grigory Simin, Asif Khan
Faculty Publications
We report on the study of high-field performance of Si-doped n-AlN layers that were grown using a pulsed metalorganic chemical vapor deposition (PMOCVD) process. In the past we showed this pulsed doping approach to lead to doping efficiency superior to that in the conventional MOCVD process. Here using them as the drift layer for a quasi-vertical conduction Schottky barrier, we show their ability to withstand high reverse bias voltages and sustain an electrical field as high as 9.9 MV cm−1. Our study thus demonstrates the viability of the PMOCVD growth and doping approach to yield n-AlN layers suitable …
Understanding The Effects Of Binder Dissolution Dynamics On The Chemistry And Performance Of Lithium–Sulfur Batteries, Saheed A. Lateef, John Chmiola, Fabio Albano, William E. Mustain, Golareh Jalilvand
Understanding The Effects Of Binder Dissolution Dynamics On The Chemistry And Performance Of Lithium–Sulfur Batteries, Saheed A. Lateef, John Chmiola, Fabio Albano, William E. Mustain, Golareh Jalilvand
Faculty Publications
Lithium–sulfur batteries (LSBs) are promising next-generation energy storage devices due to their higher theoretical specific energy and lower cost compared to conventional Lithium-ion batteries. However, their practical implementation has been hindered by severe performance degradation during extended cycling, primarily driven by shuttling of soluble sulfur discharge products (polysulfides) between the cathode and anode leading to capacity loss. In this work, we investigate the impact of selected binders and solvents, highlighting the effect of the dissolution process of the binder in solvent, on the structural properties and electrochemical performance of sulfur cathode. It is demonstrated for a variety of binders that …
Cellular Automaton Simulation Of Grain And Sub-Grain Evolution With Eutectic Growth In Laser Scanned And Rescanned A1-10si, With Experimental Validation, Kai Kang, Lang Yuan, Can Sun, Javier Miranda, André B. Phillion
Cellular Automaton Simulation Of Grain And Sub-Grain Evolution With Eutectic Growth In Laser Scanned And Rescanned A1-10si, With Experimental Validation, Kai Kang, Lang Yuan, Can Sun, Javier Miranda, André B. Phillion
Faculty Publications
This study presents a three-dimensional Cellular Automaton (3D CA) model incorporating eutectic growth mechanisms to simulate grain and sub-grain structure evolution in an additive manufacturing (AM) scenario, with surface laser rescanning of Al–10Si alloy as a case study. Unlike conventional CA models in AM, this work introduces a eutectic solidification framework within the CA approach, allowing dynamical transitions between dendritic and eutectic growth modes based on local thermal and solute conditions. The CA model integrates finite element analysis (FEA)-derived thermal data, solute redistribution tracking, nucleation behaviors, and growth kinetics under rapid solidification conditions in laser scanning and rescanning. The simulation …
Life Cycle Costs Of The Little Cottonwood Canyon Transportation Scenarios Under Varied Economic Conditions And Analysis Periods, Emma Reeves, Dane Richards, Darrell Sonntag
Life Cycle Costs Of The Little Cottonwood Canyon Transportation Scenarios Under Varied Economic Conditions And Analysis Periods, Emma Reeves, Dane Richards, Darrell Sonntag
Faculty Publications
Abstract— This study revisits the life cycle cost analysis (LCCA) of the Utah Department of Transportation’s (UDOT) proposed gondola project, using recommended best practices for selecting the discount rate, life cycle periods, and conducting a sensitivity analysis on cost projections. We reanalyze the life cycle costs of the five alternatives in the Environmental Impact Statement (EIS) (Scenario 1) across different economic scenarios, and subsequently, we reanalyze the life cycle costs of the Scaled Enhanced Bus (Scenario 2) and Enhanced Bus to Gondola (Scenario 3) from UDOT’s Revised LCCA, using construction dates in the record of decision (ROD) and considering various …
Cellular Automaton Simulation Of Grain And Sub-Grain Evolution With Eutectic Growth In Laser Scanned And Rescanned Al–10si, With Experimental Validation, Kai Kang, Lang Yuan, Can Sun, Javier Miranda, André B. Phillion
Cellular Automaton Simulation Of Grain And Sub-Grain Evolution With Eutectic Growth In Laser Scanned And Rescanned Al–10si, With Experimental Validation, Kai Kang, Lang Yuan, Can Sun, Javier Miranda, André B. Phillion
Faculty Publications
This study presents a three-dimensional Cellular Automaton (3D CA) model incorporating eutectic growth mechanisms to simulate grain and sub-grain structure evolution in an additive manufacturing (AM) scenario, with surface laser rescanning of Al–10Si alloy as a case study. Unlike conventional CA models in AM, this work introduces a eutectic solidification framework within the CA approach, allowing dynamical transitions between dendritic and eutectic growth modes based on local thermal and solute conditions. The CA model integrates finite element analysis (FEA)-derived thermal data, solute redistribution tracking, nucleation behaviors, and growth kinetics under rapid solidification conditions in laser scanning and rescanning. The simulation …
Adsorption And Electron Transfer Of Metal-Reducing Decaheme Cytochrome Protein Mtrf On Iron Oxide Nanoparticle Surfaces, Jiahuiyu Fang, Pranab Sarker, Xiaoxue Qin, Shuting Zhang, Size Zheng, Tao Wei
Adsorption And Electron Transfer Of Metal-Reducing Decaheme Cytochrome Protein Mtrf On Iron Oxide Nanoparticle Surfaces, Jiahuiyu Fang, Pranab Sarker, Xiaoxue Qin, Shuting Zhang, Size Zheng, Tao Wei
Faculty Publications
Dissimilatory metal-reducing bacteria (DMRB) transfer electrons to extracellular metal oxides via a multiheme cytochrome network. Coupling DMRB with iron oxide nanoparticles (NPs) enables continuous redox processes for various applications such as bioremediation and bioenergy. The conformation of the terminal decaheme cytochrome MtrF on the surface critically influences electron transfer (ET) efficiency. In this work, we used molecular dynamics simulations and master equations to study MtrF adsorption on 3.6 and 6.0 nm α-Fe2O3 NPs and its steady-state ET in water. Our study shows that the heme cofactors can have strong electrostatic interactions with iron oxide NP surfaces, promoting protein adsorption and …
Human Gut Commensal Alistipes Timonensis Modulates The Host Lipidome And Delivers Anti-Inflammatory Outer Membrane Vesicles To Suppress Colitis In An Il10-Deficient Mouse Model, Ethan Older, Mary K. Mitchell, Andrew Campbell, Xiaoying Lian, Michael Madden, Yuzhen Wang, Lauren E. Van De Wal, Thelma Zaw, Brandon N. Vanderveen, Rodney Tatum, E. Angela Murphy, Yan-Hua Chen, Daping Fang, Melissa Ellermann, Jie Li
Human Gut Commensal Alistipes Timonensis Modulates The Host Lipidome And Delivers Anti-Inflammatory Outer Membrane Vesicles To Suppress Colitis In An Il10-Deficient Mouse Model, Ethan Older, Mary K. Mitchell, Andrew Campbell, Xiaoying Lian, Michael Madden, Yuzhen Wang, Lauren E. Van De Wal, Thelma Zaw, Brandon N. Vanderveen, Rodney Tatum, E. Angela Murphy, Yan-Hua Chen, Daping Fang, Melissa Ellermann, Jie Li
Faculty Publications
Correlative studies have linked human gut microbes to specific health conditions. Alistipes is one such microbial genus negatively linked to inflammatory bowel disease (IBD). However, the protective role of Alistipes in IBD is understudied, and the underlying molecular mechanisms remain unknown. In this study, colonization of Il10-deficient mice with Alistipes timonensis DSM 27924 delays colitis development. Colonization does not significantly alter the gut microbiome composition, but instead shifts the host plasma lipidome, increasing phosphatidic acids while decreasing triglycerides. Outer membrane vesicles (OMVs) derived from Alistipes are detected in the plasma of colonized mice, carrying potentially immunomodulatory metabolites into the …
Low-Cost, High-Performance Electrodes For Pgm-Free Aem Water Electrolyzers: Structural Optimization Of Nimo-Based Cathodes, Mahmoud Amirsalehi, Noor Ul Hassan, Venkata Sai Sriram Mosali, Ian Street, Marjanul Manjum, Saheed Adewale Lateef, Jasmine Bohannon, Sam Mckinney, Ashutosh G. Divekar, Paul A. Kohl, Mustain E. William
Low-Cost, High-Performance Electrodes For Pgm-Free Aem Water Electrolyzers: Structural Optimization Of Nimo-Based Cathodes, Mahmoud Amirsalehi, Noor Ul Hassan, Venkata Sai Sriram Mosali, Ian Street, Marjanul Manjum, Saheed Adewale Lateef, Jasmine Bohannon, Sam Mckinney, Ashutosh G. Divekar, Paul A. Kohl, Mustain E. William
Faculty Publications
Water electrolysis technologies for hydrogen production are receiving significant attention due to a drastic reduction in the cost of renewable energy sources in recent years. Though traditional alkaline and proton exchange membrane water electrolyzers are receiving the most commercial attention, the anion exchange membrane water electrolyzer (AEMEL) has the potential to be much lower in cost. AEMELs have recently shown remarkable progress in terms of performance and durability. However, they are still mostly operated with expensive platinum group metal (PGM) catalysts on both the anode and cathode. To achieve low cost, either PGM-free or ultra-low loading PGM catalysts are needed. …
Investigation Of Stability And Control Shortcomings Of The North American X-15, William Lorenzo, Ramana Grandhi, Timothy T. Takahashi
Investigation Of Stability And Control Shortcomings Of The North American X-15, William Lorenzo, Ramana Grandhi, Timothy T. Takahashi
Faculty Publications
There is growing interest in the design of maneuvering high-speed aircraft to fly within or at the edge of the atmosphere. We identify and develop novel quasi-static vehicle screening methodologies, suitable for use during preliminary design, to better predict an incipient loss of control due to the dynamic effects of feedback. We validate these metrics by reverse-engineering Neil Armstrong’s 1962 loss of control and inadvertent atmospheric skip while piloting the X-15. In 1962, then-extant flight dynamics screening methods did not forecast likely troubles. We assemble and refine a collection of predictive metrics which operate upon basic quasi-static aerodynamic data and …
Eliminating Assay Background Of A Low-Cost, Colorimetric Glutamine Biosensor By Engineering An Alternative Formulation Of Cell-Free Protein Synthesis, Joseph P. Talley, Tyler J. Free, Tyler P. Green, Dallin M. Chipman, Bradley Charles Bundy
Eliminating Assay Background Of A Low-Cost, Colorimetric Glutamine Biosensor By Engineering An Alternative Formulation Of Cell-Free Protein Synthesis, Joseph P. Talley, Tyler J. Free, Tyler P. Green, Dallin M. Chipman, Bradley Charles Bundy
Faculty Publications
Glutamine is an essential biomolecule that plays a pivotal role in many diseases, such as cancer, where it can serve as fuel for rapid proliferation. Treatments for these diseases can be monitored and optimized through the detection of glutamine, though standard glutamine detection procedures are costly and require complex instrumentation. Cell-free protein synthesis (CFPS) has recently enabled a paper-based, colorimetric glutamine sensor that carries the potential to increase test accessibility while dramatically reducing consumer cost to enable at-home, rapid treatment monitoring. Test sensitivity remained limited by residual assay background, thus motivating this work where CFPS reactions traditionally formulated with glutamate …
War, Wounds, And Strategy: Patient Movement Lessons From The World Wars For Great Power Competition, Phillip R. Jenkins
War, Wounds, And Strategy: Patient Movement Lessons From The World Wars For Great Power Competition, Phillip R. Jenkins
Faculty Publications
This thesis examines the evolution of the U.S. military's patient movement system during World War I and World War II to evaluate how well it may perform under the conditions of future large-scale combat operations. It asks whether the United States can move, treat, and sustain wounded personnel at the scale and pace required to preserve combat power in a prolonged, high-intensity conflict. Using detailed case studies of the Meuse-Argonne Offensive and the Battle of the Bulge, the analysis focuses on how transportation platforms, organizational structure, and standard operating procedures (SOPs) shaped patient movement under conditions of attrition, disruption, and …
Surface Resistivity Correlation To Nano-Defects In Laser Powder Bed Fused Molybdenum (Mo)-Silicon Carbide (Sic) Alloys, Andrew Mason, Larry W. Burggraf, Ryan A. Kemnitz, Nate Ellsworth
Surface Resistivity Correlation To Nano-Defects In Laser Powder Bed Fused Molybdenum (Mo)-Silicon Carbide (Sic) Alloys, Andrew Mason, Larry W. Burggraf, Ryan A. Kemnitz, Nate Ellsworth
Faculty Publications
The integration of Silicon Carbide (SiC) nanoparticles into Laser Powder Bed Fusion (LB-PBF) Molybdenum (Mo) printing represents a significant advancement in refractory metal additive manufacturing. Our investigation examined how varying SiC nanoparticle sizes affect the microstructural and electrical properties of LB-PBF-printed molybdenum components while maintaining a 0.01 mass fraction of Mo. At an Linear Energy Densities (LED) of 1.8 J/mm, the addition of 80 nm SiC particles achieved a 46% reduction in porosity, while sheet resistance decreased by 6% at LED of 2.0 J/mm with 80 nm SiC particles. These performance improvements stem from several mechanisms: SiC particles serve as …
Extreme Bandgap Polarization Doped Algan Layers On Bulk Aln For Pn-Diodes With An 8.5 Mv Cm−1 Breakdown Field And Forward Current Density Exceeding 20 Ka Cm−2, Tariq Jamil, Abdullah Al Mamun Mazumder, Muhammad Ali, Mafruda Rahman, Kenneth Stephenson, Grigory Simin, Asif Khan
Extreme Bandgap Polarization Doped Algan Layers On Bulk Aln For Pn-Diodes With An 8.5 Mv Cm−1 Breakdown Field And Forward Current Density Exceeding 20 Ka Cm−2, Tariq Jamil, Abdullah Al Mamun Mazumder, Muhammad Ali, Mafruda Rahman, Kenneth Stephenson, Grigory Simin, Asif Khan
Faculty Publications
In this paper we present a study of distribution polarization doped AlxGa1−xN layers and their use in quasi-vertical configuration pn-diodes which exhibited a high breakdown field of ∼8.5 MV cm−1 and a large forward current density (∼23 kA cm−2). We also establish their potential use in UVC light emitters by studying the optical emission from a quantum well inserted at the distribution polarization doped pn-junction interface.
Impact Of Prior Exposures On Biomarkers Of Blast During Military Tactical Training, Zhaoyu Wang, Shengnan Sun, Alis Aksar Kranfli, Jeffrey Nemes, Molly J. Sullan, Andrew J. Hoisington, Lisa A. Brenner, Miciej Skotak, Christina R. Lavalle, Yongchao Ge, Walter Carr, Fatemah Haghighi
Impact Of Prior Exposures On Biomarkers Of Blast During Military Tactical Training, Zhaoyu Wang, Shengnan Sun, Alis Aksar Kranfli, Jeffrey Nemes, Molly J. Sullan, Andrew J. Hoisington, Lisa A. Brenner, Miciej Skotak, Christina R. Lavalle, Yongchao Ge, Walter Carr, Fatemah Haghighi
Faculty Publications
Blast injuries and subclinical effects are of significant concern among those Service Members (SMs) participating in military operations and tactical trainings. Studies of SMs repeatedly exposed during training find concussion-like symptomology with transient decrements in neurocognitive performance, and alterations in blood biomarkers. How prior mild TBI (mTBI) history interacts with low-level blast (LLB) exposure, however, remains unexplored, which we investigate in the present study, to identify interindividual biomarker changes from LLB exposures influenced by prior history of mTBI.
Untethered Isoperimetric Robotic Truss For Lunar Applications, Mihai Stanciu, Spencer Stowell, Isaac Weaver, Adam Rose, Chris Paul, James Wade, Ashleigh Cerven, Annie O'Bryan, Brian Bodily, Logan Yang, Nathan Usevitch
Untethered Isoperimetric Robotic Truss For Lunar Applications, Mihai Stanciu, Spencer Stowell, Isaac Weaver, Adam Rose, Chris Paul, James Wade, Ashleigh Cerven, Annie O'Bryan, Brian Bodily, Logan Yang, Nathan Usevitch
Faculty Publications
We introduce a robotic system designed to function as a lightweight, modular, and reconfigurable structure on the Moon. This robust system consists of truss-like robotic triangles, each formed by a continuous inflated fabric tube routed through two robotic roller units and a connecting unit. When deflated, these triangles can be compacted to roughly the volume of the roller units, offering an advantageous stowed-to-deployed volume ratio of 1 to 6.24. Upon inflation, the roller units pinch the tubes, creating corners by reducing the bending stiffness of the tube. Once fully deployed, electric motors move the robotic roller units along the tube, …
Review Of Tethered Unmanned Aerial Vehicles: Building Versatile And Robust Tethered Multirotor Uav System, Dario Handrick, Mattie Eckenrode, Junsoo Lee
Review Of Tethered Unmanned Aerial Vehicles: Building Versatile And Robust Tethered Multirotor Uav System, Dario Handrick, Mattie Eckenrode, Junsoo Lee
Faculty Publications
This paper presents a comprehensive review of tethered unmanned aerial vehicles (UAVs), focusing on their challenges and potential applications across various domains. We analyze the dynamic characteristics of tethered UAV systems and address the unique challenges they present, including complex tether dynamics, impulsive forces, and entanglement risks. Additionally, we explore application-specific challenges in areas such as payload transportation and ground-connected systems. The review also examines existing tethered UAV testbed designs, highlighting their strengths and limitations in both simulation and experimental settings. We discuss advancements in multi-UAV cooperation, ground–air collaboration through tethers, and the integration of retractable tether systems. Moreover, we …
How Extreme Rainfall And Failing Dams Unleashed The Derna Flood Disaster, Ayman Mokhtar Nemnem, Ahad Hasan Tanim, Audrika Nahian, Sadik Khan, Erfan Goharian, Jasim Imran
How Extreme Rainfall And Failing Dams Unleashed The Derna Flood Disaster, Ayman Mokhtar Nemnem, Ahad Hasan Tanim, Audrika Nahian, Sadik Khan, Erfan Goharian, Jasim Imran
Faculty Publications
On September 11, 2023, Storm Daniel unleashed unprecedented rainfall over the Wadi Derna watershed, triggering one of the most devastating floods in modern history, striking Derna, a coastal city in Libya. This study reconstructs the disaster using an integrated modeling approach that combines satellite imagery, hydrologic, hydraulic, and geotechnical simulations, machine learning, eyewitness accounts, and digital elevation data to assess the impact of cascading dam failures. Our findings reveal that the region’s dams, even if structurally sound, would have provided minimal protection against the extreme runoff. However, their failure unleashed a destructive surge wave, amplifying the disaster’s magnitude and devastation. …