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Articles 1501 - 1530 of 4180
Full-Text Articles in Engineering
Quality By Design Procedure For Continuous Pharmaceutical Manufacturing: An Integrated Flowsheet Model Approach, Ashley Vezina
Quality By Design Procedure For Continuous Pharmaceutical Manufacturing: An Integrated Flowsheet Model Approach, Ashley Vezina
Electronic Theses and Dissertations
Pharmaceutical manufacturing is crucial to global healthcare and requires a higher, more consistent level of quality than any other industry. Yet, the traditional pharmaceutical batch manufacturing has remained largely unchanged in the last fifty years due to high R&D costs, shorter patent durations, and regulatory uncertainty. This has led regulatory bodies to promote modernization of manufacturing process to continuous pharmaceutical manufacturing (CPM) by introducing new methodologies including quality by design, design space, and process analytical technology (PAT). This represents a shift away from the traditional pharmaceutical manufacturing way of thinking towards a risk based approach that promotes increased product and …
Advanced Liquid Crystal Displays With Supreme Image Qualities, Haiwei Chen
Advanced Liquid Crystal Displays With Supreme Image Qualities, Haiwei Chen
Electronic Theses and Dissertations
Several metrics are commonly used to evaluate the performance of display devices. In this dissertation, we analyze three key parameters: fast response time, wide color gamut, and high contrast ratio, which affect the final perceived image quality. Firstly, we investigate how response time affects the motion blur, and then discover the 2-ms rule. With advanced low-viscosity materials, new operation modes, and backlight modulation technique, liquid crystal displays (LCDs) with an unnoticeable image blur can be realized. Its performance is comparable to an impulse-type display, like cathode ray tube (CRT). Next, we propose two novel backlight configurations to improve an LCD's …
Fire Safety And Emergency Evacuation Training For Occupants Of Building Using 3d Virtual Simulation, Sayli Bhide
Fire Safety And Emergency Evacuation Training For Occupants Of Building Using 3d Virtual Simulation, Sayli Bhide
Electronic Theses and Dissertations
With advancement in technology, building structures are becoming bigger and more complex. Incidences of horrifying fires that occur in such complex structures resulting in loss of property as well as lives are recorded worldwide. Emergency evacuation training can play a crucial role in mitigating damage not only in cases of fire, explosion or chemical spill but also in cases of natural calamities like floods and hurricanes. Conventional safety training provided in industries mostly comprises of unidirectional flow of information. Due to this passive learning style, response of employees in real life emergency situations is known to be ineffective. The proposed …
Enhanced Ablation By Femtosecond And Nanoseond Pulses, Haley Kerrigan
Enhanced Ablation By Femtosecond And Nanoseond Pulses, Haley Kerrigan
Electronic Theses and Dissertations
Laser ablation of GaAs by a combination of femtosecond and nanosecond pulses is investigated as a means of enhancing material removal by a femtosecond pulse in the filamentation intensity regime. We demonstrate for the first time increased ablation of GaAs by ultrafast laser pulse plasmas augmented by nanosecond pulse radiation from a secondary laser. Material removal during laser ablation is a complex process that occurs via multiple mechanisms over several timescales. Due to different pulse durations, ablation by femtosecond and nanosecond pulses are dominated by different mechanisms. Ablation can be enhanced by optimally combining a femtosecond and nanosecond pulse in …
Laser-Induced Crystallization Mechanisms In Chalcogenide Glass Materials For Advanced Optical Functionality, Laura Sisken
Laser-Induced Crystallization Mechanisms In Chalcogenide Glass Materials For Advanced Optical Functionality, Laura Sisken
Electronic Theses and Dissertations
Glass-ceramics (GC) are promising candidates for gradient refractive index (GRIN) optics. These multi-phase, composite materials also exhibit improved physical properties as compared to the parent base glass resulting from the formation of a secondary crystalline phase(s). Nanocrystal phase formation in a multi-component chalcogenide glass (ChG), (GeSe2-3As2Se3)(1-x)-(PbSe)x glass where x = 0-40 has been investigated, and the role of the starting material morphology has been correlated to the resulting composite's optical properties including refractive index, transmission, dispersion, and thermo-optic coefficient. Optical property evolution was related to the type and amount of the crystal phases formed, since through control of the local …
Reducing Side-Sweep Accidents With Vehicle-To-Vehicle Communications, Gamini Bulumulle
Reducing Side-Sweep Accidents With Vehicle-To-Vehicle Communications, Gamini Bulumulle
Electronic Theses and Dissertations
This dissertation present contributions to the understanding of the causes of a side-sweep accidents on multi-lane highways using computer simulation. Side-sweep accidents are one of the major causes of loss of life and property damage on highways. This type of accident is caused by a driver initiating a lane change while another vehicle is blocking the road in the target lane. Our objective in the research described in this dissertation was to understand and simulate the different factors which affect the likelihood of side sweep accidents. For instance, we know that blind spots, parts of the road that are not …
Carbon Nanotube (Cnt) Metallic Composite With Focus On Processing And The Resultant Properties, Md Muktadir Billah
Carbon Nanotube (Cnt) Metallic Composite With Focus On Processing And The Resultant Properties, Md Muktadir Billah
Electronic Theses and Dissertations
Metal-carbon nanotubes (CNTs) composites are the promising advanced materials that are being developed to take the advantage of the exceptional properties of CNTs. Because of the intrinsically strong in-plane atomic SP2 bonding CNTs offer high young's modulus (1.0–1.8 TPa), high tensile strength (30–200 GPa) and high elongation at break (10–30%). The thermal conductivity of individual single-walled carbon nanotube (SWCNT) and multi-walled carbon nanotube (MWCNT) are about 6000 W/m-K and 3000 W/m-K, respectively. Therefore it is expected that by incorporation of CNTs in metal matrices multi-functional composites can be used ideally as thermal interface materials, light-weight high-strength structural materials, electric components, …
Combustion Of 1,3-Butadiene Behind Reflected Shocks, Joseph Lopez
Combustion Of 1,3-Butadiene Behind Reflected Shocks, Joseph Lopez
Electronic Theses and Dissertations
The chemical kinetics of 1,3-butadiene (1,3-C4H6) are important because 1,3-butadiene is a major intermediate during the combustion of real fuels. However, there is only limited information on the chemical kinetics of 1,3-butadiene combustion, which has applications in several combustion schemes that are currently being developed, including spark-assisted homogeneous charge compression ignition and fuel reformate exhaust gas recirculation. In the present work, the ignition delay times of 1,3-butadiene mixtures has been investigated using pressure data. Oxidation of 1,3-butadiene/oxygen mixtures diluted in argon or nitrogen at equivalence ratios (Φ) of 0.3 behind reflected shock waves has been studied at temperatures ranging from …
Computational Fluid Dynamics Study Of Thromboembolism As A Function Of Shunt Size And Placement In The Hybrid Norwood Palliative Treatment Of Hypoplastic Left Heart Syndrome, John Seligson
Electronic Theses and Dissertations
The Hybrid Norwood procedure has emerged as a promising alternative palliative first stage treatment for infants with Hypoplastic Left Heart Syndrome (HLHS). The procedure is done to provide necessary blood flow to the pulmonary and systemic regions of the body. The procedure can affect hemodynamic conditions to be pro-thrombotic, and thrombus particles can form and release from the vessel walls and enter the flow. Assuming these particles are formed and released from the shunt surface, a Computational Fluid Dynamics (CFD) model can be used to mimic the patient's vasculature geometry and predict the occurrence of embolization to the carotid or …
Hydrodynamic Measurements Of The Flow Structure Emanating From A Multi-Row Film Cooling Configuration, Michael Voet
Hydrodynamic Measurements Of The Flow Structure Emanating From A Multi-Row Film Cooling Configuration, Michael Voet
Electronic Theses and Dissertations
The demand for more power is rapidly increasing worldwide. Attention is turned to increasing the efficiency of modern methods for power generation. Gas turbines provide 35% of the power demands within the United States. Efficiency of gas turbines is defined in an ideal sense by the thermal efficiency of the Brayton Cycle. The overall efficiency of a gas turbine can be increased while simultaneously maximizing specific work output, by increasing the turbine inlet temperature. However, even with the advancements in modern materials in terms of maximum operating temperature, various components are already subjected to temperatures higher than their melting temperatures. …
Simultaneous Imaging Of The Diatomic Carbon And Methylidyne Species Radicals For The Quantification Of The Fuel To Air Ratio From Low To High Pressure Combustion, Jonathan Reyes
Electronic Theses and Dissertations
The radical intensity ratio of the diatomic carbon to methylidyne was characterized at initial pressures up to 10 bar using certified gasoline of 93% octane. This gasoline was selected due to its availability as a common fuel. The characterization of the radical intensity ratio of gasoline at elevated pressures enabled the creation of a calibration map of the equivalence ratio at engine relevant conditions. The proposed calibration map acts as a feedback loop for a combustor. It allows for the location of local rich and lean zones. The local information acquired can be used as an optimization parameter for injection …
Simulations Of Impinging Jet With A Range Of Configuration, Devansh Singh
Simulations Of Impinging Jet With A Range Of Configuration, Devansh Singh
Electronic Theses and Dissertations
Impinging jet technique is widely increasing across the globe due to its ability to produce high heat and mass transfer as compared to other traditional methods. Three cases of impinging jets related to cooling technologies for a gas turbine were investigated. The first case involves a single jet impinging on a flat plate. The second case has an array of jets impinging on a curved surface. The third case deals with simulating impinging jet in crossflow. The first case was used for validation and shows the effect of mesh and inlet boundary conditions. After careful observation, it was seen that …
Cfd Analysis Methods For Systems Driven By Natural Convection, Aaron Propst
Cfd Analysis Methods For Systems Driven By Natural Convection, Aaron Propst
Electronic Theses and Dissertations
Natural convection driven flows are present in many engineering applications such as HVAC, electronics cooling, and cryogenic systems. Predicting the flow behavior of such systems requires experimentation or numerical simulation through Computational Fluid Dynamics due to the complex interactions of natural convection. Recent advances in computing resources have made CFD increasingly popular for engineering analysis of fluid dynamics and heat transfer. CFD simulation has several advantages over experimentation including: 1) cost, 2) ease of changing design parameters, and 3) time required to obtain results. These advantages lead to an increased likelihood of discovering an optimal design. However, systems with complex …
Uav-Based Bridge Inspection And Computational Simulations, Luis Duque
Uav-Based Bridge Inspection And Computational Simulations, Luis Duque
Electronic Theses and Dissertations
The use of Unmanned Aerial Vehicles (UAV), commonly known as drones, has significantly increased in the field of civil engineering due to the poor condition of the United States’ infrastructure. The American Society of Civil Engineers (ASCE) recently reported that more than 9.1% of the United States’ bridges were structurally deficient and required attention and maintenance to ensure appropriate structural performance. Meanwhile, current practices are expensive and unsafe for bridge inspectors, requiring innovative and safer methods for the study of bridges. The goal of this paper was to identify better techniques to not only inspect, quantify, and determine the effect …
Mathematical Modeling And Capacity Fading Study In Porous Current Collector Based Lithium Ion Battery, Surendra Bajagain
Mathematical Modeling And Capacity Fading Study In Porous Current Collector Based Lithium Ion Battery, Surendra Bajagain
Electronic Theses and Dissertations
Lithium ion (Li-ion) batteries are primary energy storage devices especially in electronic gadgets, electric vehicles and for stationary storage of intermittent renewable energy. These applications demand durable Li-ion batteries with higher energy density. Energy density can be increased either by finding novel electrode materials or by modifying the existing design of the battery. The electrode materials or modified design should not only increase energy density, but also should control the capacity fading of the battery. In this work, existing mathematical model of Li-ion battery was adjusted in the case of the porous current collector. The discharge performance and capacity fading …
System Identification Of A Circulation Control Unmanned Aerial Vehicle, Mohammed Agha
System Identification Of A Circulation Control Unmanned Aerial Vehicle, Mohammed Agha
Electronic Theses and Dissertations
The advancement in automation and sensory systems in recent years has led to an increase the demand of UAV missions. Due to this increase in demand, the research community has gained interest in investigating UAV performance enhancing systems. Circulation Control (CC), which is an active control flow method used to enhance UAV lift, is a performance enhancing system currently studied. In prior research, experimental studies have shown that Circulation Control wings (CCW) implemented on class-I UAVs can reduce take-off distance by 54%. Wind tunnel tests reveal that CC improves aircraft payload capabilities through lift enhancement. Increasing aircraft payload capabilities causes …
A Methodology For Internet Of Things Business Modeling And Analysis Using Agent-Based Simulation, Mohammed Basingab
A Methodology For Internet Of Things Business Modeling And Analysis Using Agent-Based Simulation, Mohammed Basingab
Electronic Theses and Dissertations
Internet of Things (IoT) is a new vision of an integrated network covering physical objects that are able to collect and exchange data. It enables previously unconnected devices and objects to become connected using equipping devices with communication technology such as sensors and radio frequency identification tags (RFID). As technology progresses towards new paradigm such as IoT, there is a need for an approach to identify the significance of these projects. Conventional simulation modeling and data analysis approaches are not able to capture the system complexity or suffer from a lack of data needed that can help to build a …
Enhancement Of Antenna Array Performance Using Reconfigurable Slot-Ring Antennas And Integrated Filter/Antennas, Tianjiao Li
Enhancement Of Antenna Array Performance Using Reconfigurable Slot-Ring Antennas And Integrated Filter/Antennas, Tianjiao Li
Electronic Theses and Dissertations
As modern communication system technology develops, the demand for devices with smaller size, higher efficiency, and more functionality has increased dramatically. In addition, highly integrated RF-front-end modules with a reduced footprint and less transition loss between cascaded devices are desirable in most advanced wireless communication systems. Antenna arrays are widely used in wireless communication systems due to their high directivity and beam steering capability. Moreover, antenna arrays are preferred in mobile communication systems for diversity reception to reduce signal fading effects. In order to meet the various requirements of rapidly developing wireless communication systems, low cost, compact, multifunctional integrated antenna …
Reducing The Overhead Of Memory Space, Network Communication And Disk I/O For Analytic Frameworks In Big Data Ecosystem, Xuhong Zhang
Reducing The Overhead Of Memory Space, Network Communication And Disk I/O For Analytic Frameworks In Big Data Ecosystem, Xuhong Zhang
Electronic Theses and Dissertations
To facilitate big data processing, many distributed analytic frameworks and storage systems such as Apache Hadoop, Apache Hama, Apache Spark and Hadoop Distributed File System (HDFS) have been developed. Currently, many researchers are conducting research to either make them more scalable or enabling them to support more analysis applications. In my PhD study, I conducted three main works in this topic, which are minimizing the communication delay in Apache Hama, minimizing the memory space and computational overhead in HDFS and minimizing the disk I/O overhead for approximation applications in Hadoop ecosystem. Specifically, In Apache Hama, communication delay makes up a …
Analyses Of Pultruded Polyester/ E-Glass Composites Subjected To Environmental Degradation, Cameron Bosley
Analyses Of Pultruded Polyester/ E-Glass Composites Subjected To Environmental Degradation, Cameron Bosley
Electronic Theses and Dissertations
This paper evaluates the response of experimental mold releases for a pultruded glass fiber reinforced polymer (gfrp). The initial assessment criteria include comparisons between pull forces and surface appearances for each mold release. Composites fabricated using experimental mold releases that exhibited acceptable properties for both were used for further mechanical characterization that included environmental aging for two different exposure lengths (500 hours and 1000 hours) in five different environments: UV, bleach, hydrochloric acid, distilled water at 125â°f, and room temperature salt water. Three-point flexural bending and short beam strength tests were undertaken to determine the effects these environments would have …
Statistical Shape Modeling To Quantify Variation In The Proximal Humeral Anatomy, Paul B. Sade Sr.
Statistical Shape Modeling To Quantify Variation In The Proximal Humeral Anatomy, Paul B. Sade Sr.
Electronic Theses and Dissertations
The fit of the humeral prosthesis to the intramedullary canal and the replication of the anatomic humeral head center are important factors in Total Shoulder Arthroplasty (TSA). The objective of this thesis was to develop a Statistical Shape Model (SSM) of the cortical and cancellous bone regions of the proximal humerus, and to assess potential shape differences with gender and ethnicity, with a goal of informing implant design. An SSM was used and Principal Component Analysis (PCA) was applied to data that represented both the cancellous and cortical humeral bone of 63 healthy subjects and cadavers. Anatomical measurements and PC …
Six Degrees Of Freedom: Kinematics Of The Healthy Ankle Syndesmosis Joint, Veronica A. Hogg-Cornejo
Six Degrees Of Freedom: Kinematics Of The Healthy Ankle Syndesmosis Joint, Veronica A. Hogg-Cornejo
Electronic Theses and Dissertations
Syndesmotic injury, more commonly known as a "high ankle sprain", accounts for over 12% of all ankle sprain incidents in the US; of which, over 25% occur during a sporting activity. Typically, harm to the syndesmosis occurs in sports such as football, soccer, lacrosse, and hockey where it is common for an athlete to experience rapid and extreme dorsiflexion-external rotations of the foot. Severe syndesmotic sprains have been noted by clinicians as the most difficult ankle injury to accurately diagnose and treat, require the most recuperation time, and often results in life-long dysfunction. Even more problematic, 40% of patients suffering …
Specimen-Specific Natural, Pathological, And Implanted Knee Mechanics Using Finite Element Modeling, Azhar Akber Ali
Specimen-Specific Natural, Pathological, And Implanted Knee Mechanics Using Finite Element Modeling, Azhar Akber Ali
Electronic Theses and Dissertations
There is an increasing incidence of knee pain and injury among the population, and increasing demand for higher knee function in total knee replacement designs. As a result, clinicians and implant manufacturers are interested in improving patient outcomes, and evaluation of knee mechanics is essential for better diagnosis and repair of knee pathologies. Common knee pathologies include osteoarthritis (degradation of the articulating surfaces), patellofemoral pain, and cruciate ligament injury and/or rupture. The complex behavior of knee motion presents unique challenges in the diagnosis of knee pathology and restoration of healthy knee function. Quantifying knee mechanics is essential for developing successful …
Statistical Shape And Intensity Modeling Of The Shoulder, Irene Sintini
Statistical Shape And Intensity Modeling Of The Shoulder, Irene Sintini
Electronic Theses and Dissertations
Anatomical variability in the shoulder is inherently present and can influence healthy and pathologic biomechanics and ultimately clinical decision-making. Characterizing variation in bony morphology and material properties in the population can support treatment and specifically the design, via shape and sizing, of shoulder implants. Total Shoulder Arthroplasty (TSA) is the treatment of choice for glenohumeral osteoarthritis as well as bone fracture. Complications and poor outcomes in TSA are generally influenced by the inability of the implant to replicate the natural joint biomechanics and by the bone quality around the fixation features. For this reason, knowledge of bony morphology and mechanical …
Design And Modeling Of A Heat Exchanger For Porous Combustor Powered Steam Generators In Automotive Industry, Apratim Dasgupta
Design And Modeling Of A Heat Exchanger For Porous Combustor Powered Steam Generators In Automotive Industry, Apratim Dasgupta
Electronic Theses and Dissertations
A major challenge faced by automobile manufacturers is to achieve reduction of particulate emission to acceptable standards, as the emission standards become more and more stringent. One of the ecologically friendly options to reduce emissions is to develop external combustion in a steam engine as a replacement of the internal combustion engine. There are multiple factors, other than pollution that need to be considered for developing a substitute for Internal Combustion Engine, like specific power, throttle response, torque speed curve, fuel consumption and refueling infrastructure. External combustion in a steam engine seems to be a bright idea, for a cleaner …
Implementation Of Optical Interferometry And Spectral Reflectometry For High Fidelity Thin Film Measurements, Armando Arends-Rodriguez
Implementation Of Optical Interferometry And Spectral Reflectometry For High Fidelity Thin Film Measurements, Armando Arends-Rodriguez
Electronic Theses and Dissertations
An in-house reflectometer/interferometer has been built to investigate the varying curvature and thickness profiles in the contact line region of air, acetone, iso-octane, ethanol, and water on various types of substrates. Light intensity measurements were obtained using our reflectometer/interferomter and then analyzed in MATLAB to produce thickness and curvature profiles. The apparatus is based on the principle of a reflectometer, consisting of different optical elements, probe, light source, and spectrometer. Our reflectometer/interferomter takes measurements in the UV-Vis-IR range (200nm-1000nm). This range is achieved by using a light source that has both a deuterium light (190nm-800nm), a tungsten halogen light (400nm-1100nm), …
On Distributed Estimation For Resource Constrained Wireless Sensor Networks, Alireza Sani
On Distributed Estimation For Resource Constrained Wireless Sensor Networks, Alireza Sani
Electronic Theses and Dissertations
We study Distributed Estimation (DES) problem, where several agents observe a noisy version of an underlying unknown physical phenomena (which is not directly observable), and transmit a compressed version of their observations to a Fusion Center (FC), where collective data is fused to reconstruct the unknown. One of the most important applications of Wireless Sensor Networks (WSNs) is performing DES in a field to estimate an unknown signal source. In a WSN battery powered geographically distributed tiny sensors are tasked with collecting data from the field. Each sensor locally processes its noisy observation (local processing can include compression, dimension reduction, …
Ichetucknee Springs: Measuring The Effects Of Visitors On Water Quality Parameters Through Continuous Monitoring., Sarah Faraji
Ichetucknee Springs: Measuring The Effects Of Visitors On Water Quality Parameters Through Continuous Monitoring., Sarah Faraji
Electronic Theses and Dissertations
Ichetucknee Springs System is in north central Florida, under the jurisdiction of the Suwannee River Water Management District (SRWMD). The Ichetucknee River is one of the most pristine spring-fed rivers in Florida and became a state park in 1970. Over 400,000 people visited the Ichetucknee Springs State Park in 2016. From that total, over 130,000 people came during the tubing season alone (Memorial Day to Labor Day). During the tubing season, only 750 visitors per day are allowed to launch from the North Launch, near the Ichetucknee Head Spring. The park enforces visitor usage of the river during these time …
Mode Evolution In Fiber Based Devices For Optical Communication Systems, Bin Huang
Mode Evolution In Fiber Based Devices For Optical Communication Systems, Bin Huang
Electronic Theses and Dissertations
Space division multiplexing (SDM) is the most promising way of increasing the capacity of a single fiber. To enable the few mode fiber (FMF) or multi-mode fiber (MMF) transmission system, several major challenges have to be overcome. One is the urgent need of ideal mode multiplexer, the second is the perfect amplification for all spatial modes, another one is the modal delay spread (MDS) due to group velocity difference of spatial modes. The main subject of this dissertation is to model, fabricate and characterize the mode multiplexer for FMF transmission. First, we designed a novel resonant mode coupler (structured directional …
Computational Fluid Dynamics Proof Of Concept And Analysis Of A Self-Powered Fontan Circulation, Marcus Ni
Computational Fluid Dynamics Proof Of Concept And Analysis Of A Self-Powered Fontan Circulation, Marcus Ni
Electronic Theses and Dissertations
The Fontan circulation is a result of the last (third stage) surgical procedure to correct a single ventricle congenital cardiac disorder in children. Although the Fontan circulation has been successfully established in surgeries over the years, it is flawed and can lead in certain cases to pre-mature death. The main cause of this failure is due to increased pulmonary vascular resistance due to loss pulse pressure and blood flow. In healthy circulations, the heart pumps directly to the lungs, where as "Single Ventricle" patients must use a single sided heart to supply blood to the rest of the body before …