Engineering Commons^™

Jme 4110 Phenode Camera Arm Design Project, Kelsey M. Wortmann, Paul Masnica, Matthias Sommer

Washington University / UMSL Mechanical Engineering Design Project JME 4110

The goal of this design project was to create an extendable camera arm capable of attaching to the shell of the PheNode in-field apparatus created by researchers at the Donald Danforth Plant Science Center. The camera arm extends 36 inches in length, can rotate 180 degrees, and successfully holds a camera for plant imaging with minimal vibrations. We have designed an affordable camera arm that is stable and meets the design parameters given. Our design process is documented in the following report.

Jme 4110 Seed Aerodynamics, Kristin Gonzalez, Vladimir Sidorov

Washington University / UMSL Mechanical Engineering Design Project JME 4110

This is a report discussing the analysis and results of a wind tunnel that was created to find the terminal velocity of a variety of seeds.

Jme 4110- Solar Panel Tracker, Bob Stretch, James Eimer, Patrick Kraus

Washington University / UMSL Mechanical Engineering Design Project JME 4110

Our design is a passive solar panel tracker using fundamentals of thermodynamics. A fixed solar tracker only operates at peak efficiency for a short period during the day. Our tracker uses the sun's energy to power pistons that push the panel to face the sun throughout the day, increasing efficiency.

Aluminosilicate Dissolution And Silicate Carbonation During Geologic Co2 Sequestration, Yujia Min

McKelvey School of Engineering Graduate Student Theses & Dissertations

Geologic CO2 sequestration (GCS) is considered a promising method to reduce anthropogenic CO2 emission. Assessing the supercritical CO2 (scCO2)¬–gas or liquid phase water (g, l)–mineral interactions is critical to evaluating the viability of GCS processes. This work contributes to our understanding of geochemical reactions at CO2¬–water (g, l)–mineral interfaces, by investigating the dissolution of aluminosilicates in CO2-acidified water (l). Plagioclase and biotite were chosen as model minerals in reservoir rock and caprock, respectively. To elucidate the effects of brine chemistry, first, the influences of cations in brine including Na, Ca, and K, have been investigated. In addition to the cations, …

Development Of High Resolution Tools For Investigating Cardiac Arrhythmia Dynamics, Christopher Reed Gloschat

McKelvey School of Engineering Graduate Student Theses & Dissertations

Every year 300,000 Americans die due to sudden cardiac death. There are many pathologies, acquired and genetic, that can lead to sudden cardiac death. Regardless of the underlying pathology, death is frequently the result of ventricular tachycardia and/or fibrillation (VT/VF). Despite decades of research, the mechanisms of ventricular arrhythmia initiation and maintenance are still incompletely understood.

A contributing factor to this lack of understanding is the limitations of the investigative tools used to study VT/VF. Arrhythmias are organ level phenomena that are governed by cellular interactions and as such, near cellular levels of resolution are needed to tease out their …

Novel Pet Systems And Image Reconstruction With Actively Controlled Geometry, Ke Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

Positron Emission Tomography (PET) provides in vivo measurement of imaging ligands that are labeled with positron emitting radionuclide. Since its invention, most PET scanners have been designed to have a group of gamma ray detectors arranged in a ring geometry, accommodating the whole patient body. Virtual Pinhole PET incorporates higher resolution detectors being placed close to the Region-of-Interest (ROI) within the imaging Field-of-View (FOV) of the whole-body scanner, providing better image resolution and contrast recover. To further adapt this technology to a wider range of diseases, we proposed a second generation of virtual pinhole PET using actively controlled high resolution …

Improving Pure-Tone Audiometry Using Probabilistic Machine Learning Classification, Xinyu Song

McKelvey School of Engineering Graduate Student Theses & Dissertations

Hearing loss is a critical public health concern, affecting hundreds millions of people worldwide and dramatically impacting quality of life for affected individuals. While treatment techniques have evolved in recent years, methods for assessing hearing ability have remained relatively unchanged for decades. The standard clinical procedure is the modified Hughson-Westlake procedure, an adaptive pure-tone detection task that is typically performed manually by audiologists, costing millions of collective hours annually among healthcare professionals. In addition to the high burden of labor, the technique provides limited detail about an individual’s hearing ability, estimating only detection thresholds at a handful of pre-defined pure-tone …

Composition-Dependent Mechanisms Of Multiscale Tendon Mechanics, Fei Fang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Tendons serve as an integral part of the musculoskeletal system by transferring loads from muscle to bone and providing joint mobility and stability. From the physiologically-loading perspective, while progress has been made in evaluating mechanical behavior of different types of tendons in tension, further work is needed to relate tendon mechanics to compositional and microstructural properties, particularly under non-tensile loading modalities (i.e., shear, compression). This information is vital to explore mechanisms of how mechanical signals lead to changes in tendon structure and composition to enable these tissues to function properly, including in in vivo multiaxial loading conditions. From the structural …

Hollow And Porous Plasmonic Nanostructures For Highly Efficient Chemical And Biological Sensing, Keng-Ku Liu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Localized surface plasmon resonance (LSPR) involves the collective and coherent oscillation of dielectrically confined conduction electrons. The LSPR wavelength of noble metal nanoparticles (such as gold, silver and copper), which falls into the visible and near infrared range of the electromagnetic spectrum, is sensitive to the composition, size, shape, dielectric properties of the surrounding medium, and proximity to other nanostructures (plasmon coupling). Based on the sensitivity of the surface plasmon resonance to the changes in the dielectric properties of the surrounding medium and the enhancement of the electromagnetic (EM) field in proximity of metal nanostructures, two important classes of plasmonic …

Photodynamic Therapy: Agents And Mechanisms, Rebecca Claire Gilson

McKelvey School of Engineering Graduate Student Theses & Dissertations

Despite enormous efforts, cancer remains a leading cause of morbidity and mortality world-wide. The main challenges currently facing cancer therapy include lack of adequate tumor targeting, failure to treat hypoxic tumor cells, and induction therapy resistant tumors. A solution to these limitations can be found in photodynamic therapy (PDT) which combines light and light activatable compounds, photosensitizers (PSs), to produce cytotoxic reactive oxygen species (ROS) to damage tumor tissue. This creates a spatiotemporal therapeutic effect, where cell damage only occurs at the intersection of the PS and light. PDT can treat tumors through unique mechanisms which reduce induction of tumor …

Numerical Methods For Nonlinear Optimal Control Problems And Their Applications In Indoor Climate Control, Runxin He

McKelvey School of Engineering Graduate Student Theses & Dissertations

Efficiency, comfort, and convenience are three major aspects in the design of control systems for residential Heating, Ventilation, and Air Conditioning (HVAC) units. In this dissertation, we study optimization-based algorithms for HVAC control that minimizes energy consumption while maintaining a desired temperature, or even human comfort in a room. Our algorithm uses a Computer Fluid Dynamics (CFD) model, mathematically formulated using Partial Differential Equations (PDEs), to describe the interactions between temperature, pressure, and air flow. Our model allows us to naturally formulate problems such as controlling the temperature of a small region of interest within a room, or to control …

Sorption Of Metals Onto Natural Sediments And Engineered Iron Oxide Nanoparticles, Zezhen Pan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Metal contamination of subsurface environments and engineered water systems can be derived from natural processes and anthropogenic activities associated with industrial processes, past weapons production, and mining works. The toxic and carcinogenic effects of uranium and chromium pose a significant risk to the environment and human health. For uranium contamination in subsurface environments, phosphate addition has been performed for in-situ immobilization, which can avoid the costs associated with pump-and-treat or excavation-based remediation strategies. The interactions of uranium and phosphate in Hanford sediments had been insufficiently explored in terms of its site-specific groundwater chemistry and aquifer sediment properties. For water treatment …

Studies In Pressurized Oxy-Combustion: Process Development And Control Of Radiative Heat Transfer, Akshay Gopan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Fossil fuels supply over 80% of the world’s primary energy and more than two-thirds of the world’s electricity. Of this, coal alone accounts for over 41% of the electricity supplied globally. Though coal is globally well-distributed and can provide stable and reliable energy on demand, it emits a large amount of carbon dioxide—a greenhouse gas responsible for global warming. Serious concerns over the implication of the increased global temperature have prompted the investigation into low carbon energy alternatives. The idea of capturing the carbon dioxide emitted from the combustion sources is considered as one of the viable alternatives. This would …

Minimum Induced Power For A Helicopter In High-Speed Forward Flight, Junsoo (Sean) Hong

McKelvey School of Engineering Graduate Student Theses & Dissertations

A dynamic inflow model is used to calculate minimum induced power for a helicopter in high-speed forward flight with infinite and finite number of blades. Comparisons between analytical and numerical results are shown and they show good agreement. Different flow conditions (such as with and without reverse flow or inflow feedback) are used to show how each condition affects optimum induced power. Several results confirm the findings of earlier investigations such as a singularity in rotor power in reverse flow and induced power reduction with increase in blade number. Some of the new findings are that greater inflow feedback (due …

Robust Odorant Recognition In Biological And Artificial Olfaction, Nalin Katta

McKelvey School of Engineering Graduate Student Theses & Dissertations

Accurate detection and identification of gases pose a number of challenges for chemical sensory systems. The stimulus space is enormous; volatile compounds vary in size, charge, functional groups, and isomerization among others. Furthermore, variability arises from intrinsic (poisoning of the sensors or degradation due to aging) and extrinsic (environmental: humidity, temperature, flow patterns) sources. Nonetheless, biological olfactory systems have been refined over time to overcome these challenges. The main objective of this work is to understand how the biological olfactory system deals with these challenges, and translate them to artificial olfaction to achieve comparable capabilities. In particular, this thesis focuses …

Designing Metabolite Biosensors And Engineering Genetic Circuits To Regulate Metabolic Pathways, Di Liu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Microbial production of chemicals has provided an attractive alternative to chemical synthesis. A key to make this technology economically viable is to improve titers, productivities, and strain robustness. However, pathway productivities and yields are often limited by metabolic imbalances that inhibit cell growth and chemical production. In contrast, natural metabolic pathways are dynamically regulated according to cellular metabolic status. Dynamic regulation allows cells to adjust metabolite concentrations to optimal levels and avoid wasting carbon and energy. Inspired by nature, synthetic regulatory circuits have shown great promise in improving titers and productivities, because they can balance the metabolism by dynamically adjusting …

Fundamental Studies Of Flame Structure Through Laser Plasma Diagnostics, Wendong Wu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Increasing concerns about air pollution and global climate change are drawing attention to the need for efficiency improvements and emission reductions for combustion processes, which account for more than 85% of energy production in United States. Combustion efficiency and emissions are affected by the mixing and reacting of fuel and oxidizer. Understanding such behavior plays a critical role in flame structure studies and combustion optimization. However, experimentally obtaining mixture fraction, which is a widely used quantity to describe the mixing behavior, has proven to be a challenge, especially for heavier hydrocarbon fuels or fuel rich flames. Moreover, measuring flame temperature …

Mechanobiology Of Epithelial Clusters In Ecms Of Diverse Mechanical Properties, Samila Nasrollahi

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cell clusters reside in complex extracellular matrices (ECMs) of varying mechanical properties. Epithelial cells sense and translate the mechanical cues presented by the surrounding ECM into biochemical signals through a process called ‘mechanotransduction’, which controls fundamental aspects of disease and development. During the course of metastasis, mechanical changes in the tumor microenvironment can lead to declustering of epithelial cells through a process called epithelial-to-mesenchymal transition (EMT). Throughout different steps of metastasis, escaped epithelial clusters encounter heterogeneous tissues of varying mechanical properties that ultimately influence their behavior in distant locations within the body. This dissertation investigates the mechanobiology of epithelial clusters …

Intrinsic And Extrinsic Biomechanical Factors In A Co-Adaptive Ecog-Based Brain Computer Interface, Jonathan Carl Landes

McKelvey School of Engineering Graduate Student Theses & Dissertations

Paralysis, due to spinal cord injury, amyotrophic lateral sclerosis (ALS), or stroke, is the result of severed communication between the brain and the motor periphery. Brain computer interfaces (BCIs) are neuroprosthetic devices that create novel communication pathways by measuring and transforming neural activity into operational commands. State of the art BCI systems measure brain activity using penetrating electrode arrays able to record from hundreds of individual cortical neurons simultaneously. Unfortunately, these systems are highly susceptible to signal degradation which limits their efficacy to 1-2 years. However, electrocorticography (ECoG) signals recorded from the surface of the brain deliver a more competitive …

Efficiently And Transparently Maintaining High Simd Occupancy In The Presence Of Wavefront Irregularity, Stephen V. Cole

McKelvey School of Engineering Graduate Student Theses & Dissertations

Demand is increasing for high throughput processing of irregular streaming applications; examples of such applications from scientific and engineering domains include biological sequence alignment, network packet filtering, automated face detection, and big graph algorithms. With wide SIMD, lightweight threads, and low-cost thread-context switching, wide-SIMD architectures such as GPUs allow considerable flexibility in the way application work is assigned to threads. However, irregular applications are challenging to map efficiently onto wide SIMD because data-dependent filtering or replication of items creates an unpredictable data wavefront of items ready for further processing. Straightforward implementations of irregular applications on a wide-SIMD architecture are prone …

Parallel Real-Time Scheduling For Latency-Critical Applications, Jing Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

In order to provide safety guarantees or quality of service guarantees, many of today's systems consist of latency-critical applications, e.g. applications with timing constraints. The problem of scheduling multiple latency-critical jobs on a multiprocessor or multicore machine has been extensively studied for sequential (non-parallizable) jobs and different system models and different objectives have been considered. However, the computational requirement of a single job is still limited by the capacity of a single core. To provide increasingly complex functionalities of applications and to complete their higher computational demands within the same or even more stringent timing constraints, we must exploit the …

Easier Parallel Programming With Provably-Efficient Runtime Schedulers, Robert Utterback

McKelvey School of Engineering Graduate Student Theses & Dissertations

Over the past decade processor manufacturers have pivoted from increasing uniprocessor performance to multicore architectures. However, utilizing this computational power has proved challenging for software developers. Many concurrency platforms and languages have emerged to address parallel programming challenges, yet writing correct and performant parallel code retains a reputation of being one of the hardest tasks a programmer can undertake.

This dissertation will study how runtime scheduling systems can be used to make parallel programming easier. We address the difficulty in writing parallel data structures, automatically finding shared memory bugs, and reproducing non-deterministic synchronization bugs. Each of the systems presented depends …

Characterization Of The High Frequency Alternating Current Block In The Rat Sciatic Nerve Using Cuff Electrodes And Macro-Sieve Electrodes, Soumyajit Ray

McKelvey School of Engineering Graduate Student Theses & Dissertations

Tripolar cuff electrodes were designed, fabricated and non-chronically implanted in the sciatic nerve of two-month-old Lewis rats. A proximal constant current stimulus to the nerve was blocked by applying a high frequency sinusoidal signal to the distally placed tripolar cuff electrode. The frequency voltage characteristic of the blocking signal was obtained. Complete block was not achieved using variants of the tripolar cuff design and bipolar cuff electrodes. Single and dual macro-sieve electrode assemblies were designed, fabricated and chronically implanted in the sciatic nerve of Lewis rats. After a four-month period for regeneration four different electrode configurations were tested to enable …

Decoupling Information And Connectivity In Information-Centric Networking, Hila Ben Abraham, Jyoti Parwatikar, John Dehart, Adam Drescher, Patrick Crowley

All Computer Science and Engineering Research

This paper introduces and demonstrates the concept of Information-Centric Transport as a mechanism for cleanly decoupling the information plane from the connectivity plane in Information-Centric Networking (ICN) architectures, such as NDN and CICN. These are coupled in today's incarnations of NDN and CICN through the use of forwarding strategy, which is the architectural component for deciding how to forward packets in the presence of either multiple next-hop options or dynamic feedback. As presently designed, forwarding strategy is not sustainable: application developers can only confidently specify strategy if they understand connectivity details, while network node operators can only confidently assign strategies …

An Improved Algorithm For Learning To Perform Exception-Tolerant Abduction, Mengxue Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Abstract

Inference from an observed or hypothesized condition to a plausible cause or explanation for this condition is known as abduction. For many tasks, the acquisition of the necessary knowledge by machine learning has been widely found to be highly effective. However, the semantics of learned knowledge are weaker than the usual classical semantics, and this necessitates new formulations of many tasks. We focus on a recently introduced formulation of the abductive inference task that is thus adapted to the semantics of machine learning. A key problem is that we cannot expect that our causes or explanations will be perfect, …

Computational Fluid Dynamics Modeling And Simulations Of Fast Fluidized Bed And Moving Bed Reactors For Chemical Looping Combustion, Mengqiao Yang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Chemical-looping combustion (CLC) is a next generation carbon capture technology with high efficiency and low cost. To assess the potential of this technology for industrial scale power plants, thousands of laboratory scale and many pilot-scale plants have been designed and tested. In recent years, to obtain a thorough understanding of the hydrodynamic behavior inside the reactors and chemical looping combustion process, high-fidelity numerical simulation using Computational Fluid Dynamics(CFD) have been performed. However, CFD simulations in the literature have been limited reported compared to the laboratory scale experiments.

In this thesis, cold flow simulations of a CLC fuel reactor are performed …

Aerodynamics And Vortex Structures Of A Flapping Airfoil In Forward Flight In Proximity Of Ground, Hang Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

The traditional flapping wing high lift mechanism research mainly focuses on the wing in unbounded flow. However, the real insect flight includes not only the unbounded flow field but also the near-surface flight. Therefore, research on near-surface flight can help reveal the high-lift mechanism of insect flight and should also be beneficial to the research on Micro-Air-Vehicles (MAV). In this thesis, the flow fields of an airfoil in hover and forward flight are simulated in the presence of ground by newly available function of “dynamic meshing” in ANSYS Fluent is employed. The characteristics of aerodynamics, pressure distribution, and vortex structure …

Temperature Corrected Turbulence Models For High Speed Compressible Flows, Shuai Shuai

McKelvey School of Engineering Graduate Student Theses & Dissertations

No abstract provided.

Cfd Simulations Of Chemical Looping Combustion In A Packed Bed And A Bubbling Bed Fuel Reactor, Guanglei Ma

McKelvey School of Engineering Graduate Student Theses & Dissertations

Chemical-looping combustion (CLC) is a next generation combustion technology that has shown great promise in addressing the need for high-efficiency low-cost carbon capture from fossil fueled power plants to address the rising carbon emissions. Although there have been a number of experimental studies on CLC in recent years, CFD simulations have been limited in the literature on CLC. The development and confidence in high-fidelity simulations of the CLC process is a necessary step towards facilitating the transition from laboratory-scale experiments to deployment of this technology on an industrial scale. In this research, first the CFD simulations of a CLC packed …

Numerical Simulation Of Flows Past A Circular And A Square Cylinder At High Reynolds Number, And A Curved Plate In Transitional Flow, Ling Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Increasing the prediction accuracy and computational efficiency of turbulence models at high Reynolds number remains a challenging problem in Computational Fluid Dynamics (CFD). In this paper, several turbulence models are applied for numerical simulation of flow past a circular and a square cylinder at high Reynolds number. Wray-Agarwal (WA) turbulence model is a recently developed one-equation turbulence model derived from k-w closure. Comparisons are made among computational results from WA model, Spalart-Allmaras (SA) model, the shear stress transport SST k-w model and the standard Wilcox k-w model. For circular cylinder, the computations are performed for Reynolds numbers and and simulation …