Engineering Commons^™

A Wheelchair-Bed Transfer Device For Patients With Limited Mobility, Malachie Nichols

Biomedical Engineering Undergraduate Honors Theses

As the population ages, eldercare becomes more important than ever, yet many caregivers lack the resources they need to safely do their jobs. For those who take care of a disabled loved-one at home or work as home health aides, basic tasks can be frustrating and even dangerous. The high physical demands of moving and lifting patients make injuries common among home health care workers. Musculoskeletal injuries to the back, shoulders, wrists, and hands are especially common. The use of transfer devices such as Hoyer lifts, slide boards, and gait belts help to make moving patients easier and safer, but …

Automated Segmentation Of Autofluorescence Lifetime Images Using A Convolutional Neural Network, Nicole Hooten

Biomedical Engineering Undergraduate Honors Theses

Chronic wounds affect nearly 1 out of every 50 people in the United States, decreasing quality of life and putting people with potential comorbidities at high risk for obtaining an infection. Wound healing progress in clinical settings is measured by tracking wound size and there are currently no non-invasive, quantitative measurement techniques. Previous studies have proposed nicotinamide adenine dinucleotide (NADH) autofluorescence lifetime (FLIM) imaging of the wound edge as a method to quantify the wound healing process by connecting the role of NADH in cellular metabolism to wound healing stage. However, evaluation of FLIM images is heavily subjective, as a …

Development Of A Computational Model To Investigate Pathways And The Effects Of Treatment In Fanconi Anemia, Sabrina Kellett

Biological Sciences Undergraduate Honors Theses

Fanconi Anemia (FA) is a rare type of anemia that is not easily studied and can have very detrimental effects. This disease compromises the bone marrow, resulting in decreased hemopoiesis. Symptoms of FA also include abnormalities in the brain and spinal cord, incorrect formation of the kidneys, abnormal formation of the heart and lungs, and a dramatically increased risk of developing cancer. FA can be caused by various mutations in any of the 22 genes that encode for proteins involved in what is called the FA DNA repair pathway. In healthy individuals, this pathway specifically repairs interstrand cross-links (ICLs) recognized …

Estimating Toxic Load From Finite-Duration Contaminant Releases In Wind Tunnel Experiments, Patrick B. Jones

Chemical Engineering Undergraduate Honors Theses

When gaseous contaminants are released into the atmosphere said contaminants form clouds that travel in the prevailing wind direction. An individual caught in the downwind path of one such cloud will accumulate a dosage, or toxic load, of said contaminant that is dependent on a multitude of environmental factors. This thesis quantifies unpredictability – or variation – in toxic load measurements using downwind concentration data captured from finite-duration gaseous contaminant releases conducted at set conditions in the Chemical Hazards Research Center ultra-low speed wind tunnel.

Finite-duration releases can be divided into two categories – time-limited steady releases and puffs – …

Ranking Highway Transportation Asset Criticality Through Stakeholder Input Using The Analytical Hierarchy Process (Ahp), Kwadwo Amankwah-Nkyi

Graduate Theses and Dissertations

The transportation system is especially vulnerable to natural and human-made disasters which can have effects on mobility, safety, and the economy. This thesis presents a method to rank transportation assets based on their criticality to the transportation system by uniquely gathering stakeholder input on criticality criteria weights. This serves as a typical first step in vulnerability and resilience assessments. Six criteria were used to estimate asset criticality: Annual Average Daily Traffic (AADT), roadway classification, freight output, tourism output, Social Vulnerability Index (SoVI), and redundancy. Then, the criteria are combined via stakeholder input using a weighted ranking scheme called the Analytical …

Comparing Firocoxib And Meloxicam In The Application Of Microneedle Patch For Transdermal Drug Delivery, Ruohan Li

Chemical Engineering Undergraduate Honors Theses

This thesis compares the performance of meloxicam and firocoxib in the aspects of its physical characteristic, chemical compositions, and in-vitro performances for transdermal pain management microneedle patches on farm animals. The microneedle patches are composed of polyvinyl alcohol (PVA), type I collagen (COL), and chitosan (CHI) as base material that carries NSAIDs to achieve therapeutic purposes. Scanning electron microscopy (SEM) was utilized to observe the morphological and physical characteristics of the microneedle patches. Both meloxicam and firocoxib microneedle patches were successfully prepared using the methodology, with organized microneedle distribution and sizing. And Fourier transform infrared spectroscopy (FTIR) confirmed the chemical …

A Teaching Unit Plan For Introducing Engineering In 1st-2nd Grade Classrooms, Claudia Smith

Chemical Engineering Undergraduate Honors Theses

The field of engineering, and specifically chemical engineering, is projected to increase significantly over the next 10 years. Engineering programs require students to have a strong foundation of math and science. Students in the United States are often underprepared to enter these programs, and the majority of high school students are not interested in pursuing a career in the STEM field at all. For this project, a unit teaching plan was created to introduce students to the field of engineering, providing a foundation for their upper-level STEM classes, and encouraging them to consider engineering as a career in the future. …

Battery Design, Construction, And Characterization For Small Motor Use Focusing On Anodic Zinc For Electron Flow, Amber Veach

Chemical Engineering Undergraduate Honors Theses

This thesis explores the construction, characterization, and application of anodic zinc batteries for powering a small electric motor for the ChemE Car competition. Two zinc galvanic cell batteries were studied: zinc-carbon and zinc-air batteries. Prototype batteries were constructed and tested for voltage, amperage, and power production. In the zinc-carbon trials, a 3:1 mixture of manganese dioxide and graphite was determined to be the best cathode for power production. The size which allowed for sufficient power while maintaining the smallest footprint on the car was a zinc can six cm tall and two cm in diameter. Analysis of paper zinc-air battery …

Heat Transfer From Plates, Leanza Trevino

Chemical Engineering Undergraduate Honors Theses

The purpose of this honors thesis is to create an experiment for the CHEG Lab I course. This is a continuation of work done by Alexa Moreno. She created an experiment to model free convection of a horizontal plate. In this report, free and forced convection of a vertical and horizontal plate, respectively are modeled. This report explains the motivation for creating this heat convection experiment, the results of performing the experiment, and provides recommendations for future work on this experiment. Lab handouts are included in the Appendix.

Greenhouse Gas Emissions From Milk Production In The Us, Cailey Cooper

Chemical Engineering Undergraduate Honors Theses

Life cycle assessment is performed to determine the environmental impacts of the life cycle of a product. In this study, the greenhouse gas emissions from milk production in the United States were calculated using a cradle-to-gate analysis. The dairy industry has a noticeable impact on the total greenhouse gas emissions in the US. Performing life cycle assessment provides information about the main emission sources in the life cycle which can spark innovative changes to reduce these emissions. The life cycle assessment was performed using the openLCA software and ReCiPe impact assessment methodology. The results indicated that 1.28 kg of carbon …

Interactions And Phenomena Between Disodium Cromoglycate And Polyelectrolytes, Brandon Tipton

Chemical Engineering Undergraduate Honors Theses

The interactions between polyelectrolytes and oppositely charged macroions have been widely studied, but few reports have been made on the interaction between chromonic mesogens and polyelectrolytes. Here, we report on the formation of liquid crystalline coacervates achieved by the liquid-liquid phase separation of an aqueous solution of negatively charged liquid crystal and polycations. As well as the occurrence of tactoids that form in the absence of these interactions. The liquid crystal that is experimented with is disodium cromoglycate, better known as DSCG. This acts as a negative charge that is paired with a variety of positively charged polyelectrolytes. The first …

Utilization Of Electrodeionization To Separate And Concentrate Cellobionic And Gluconic Acid, Andie Veeder

Chemical Engineering Undergraduate Honors Theses

Biofuel production is currently an expensive and inefficient process with many drawbacks. It is water and land intensive, competes with food production, and requires large energy inputs decreasing its relative sustainability. This paper explores the use of electrodeionization (EDI) to improve the biofuel process by separating and concentrating large, organic sugar acids that are important materials for the production of bioethanol. An EDI device was assembled for the purpose of separating and concentrating gluconic, cellobionic and lactobionic acid. Several trials were conducted and samples were analyzed to determine the success of this experiment. The results for the separation and concentration …

Characterizing And Quantifying Shear-Induced Hemolysis In A Hollow Fiber Membrane System, Siddhi Bhat

Chemical Engineering Undergraduate Honors Theses

Clinical studies have shown that patients undergoing renal replacement therapy are more susceptible to developing hemolysis, or the rupturing of red blood cells. Rapid hemolysis can cause symptoms such as anorexia, vomiting, and even death in severe cases. The aim of this study is to identify how shear stress within a hollow fiber membrane impacts the level of hemolysis that occurs. This allows for the optimization of the ultrafiltration membranes that are typically used for hemofiltration treatments. The variables being studied are the radii of hollow fibers, number of fibers, and volumetric flow rate of blood being circulated. Here, we …

Separation Of Organic Acids Through Direct Catalysis From Sugars, Katelyn Robinson

Chemical Engineering Undergraduate Honors Theses

Society relies on plastic products, whether they are single use or durable. A downside of plastic is that the most common type is a product of oil and oil is not only a limited resource but also a climate-damaging resource. Polylactic acid (PLA) is a bio-based, biodegradable plastic. However, the process of converting biomass to polylactic acid polymer has the largest environmental impact of the PLA production process, so alternative methods of conversion are needed (Moretti et al., 2021). The polylactic acid polymer can be made with lactic acid, which can be converted from glucose.

Response Of Cell Nuclei To Mechanical Strain In Synthetic Liquid Crystals, Sydnee Ehorn

Chemical Engineering Undergraduate Honors Theses

In this research project, induced mechanical stress on the cell nucleus via synthetic liquid crystals (LCs) was explored. Points of interest were the shape alterations and distortions of the nuclear envelope under strain, providing insight into the mechanics and stiffness of the cell nuclei. LCs are substances with structure and fluidity, and LCs in the nematic phase are aligned in a single direction without layers, inducing shear stress on inclusions. This study confirmed that an aqueous solution of 17.3 wt% disodium cromoglycate (DSCG) can successfully strain the nuclei of chicken red blood cells (RBCs) by examining the nuclear response to …

Simulating Dielectric Barrier Plasma Actuators With Varying Geometries, Cass Wiederkehr

Mechanical Engineering Undergraduate Honors Theses

The idea of Ionic Wind Propulsion has long been a topic of research for whether or not it can be used as a practical power source for flight. MIT researchers proved in 2018 that a plane with zero moving parts powered by Ionic Wind Propulsion was possible, and sustained flight could work with an internal power supply. However, due to the thin wire electrodes required to generate the ion cloud that made such propulsion possible, large amounts of drag rendered the plane extremely inefficient and impractical. Dielectric Barrier Discharge Devices (DBDs) are being investigated as to whether they can serve …

Characterization And Manipulation Of Double-Stranded Dna Using Atomic Force Microscopy, Lauren Skartvedt

Mechanical Engineering Undergraduate Honors Theses

An atomic force microscope (AFM) is used to scan high-resolution images on the nano scale. The lambda DNA used for this project are 48,502 base pairs in length and are double-stranded. This project utilizes the NanoSurf Core AFM in order to characterize and manipulate strands of lambda DNA which have been deposited on a mica surface. The deposition process of the DNA on the mica surface was developed by the National Institute of Standards and Technology and the University of Colorado - Boulder. The AFM is used in imaging mode to scan the mica surface to locate the DNA. When …

A Systematic Study Into The Design And Utilization Of Burn Wire As A Means Of Tensioning And Releasing Spacecraft Mechanisms Through Applied Joule Heating, Chandler Dye

Mechanical Engineering Undergraduate Honors Theses

The joule heating characteristics of Nichrome burn wires, often used as a thermal cutting device in mechanisms designed to fasten and release CubeSat deployables, are examined in the following thesis. Wires ranging from 0.125 inches to 2 inches long, and diameters of 30 Ga and 40 Ga, are investigated through analytical calculations and thermal simulations based on heat transfer due to joule heating, and through physical circuitry-based experiments. The temperature data is used to generate heating curves to predict the time it takes for Nichrome wires to fail under varying testing parameters. This research aims to catalog a series of …

Multiple Output Power Supply Using Toroidal Transformers For Medium Voltage Active Gate Drivers, Samhitha Venkata Machireddy

Graduate Theses and Dissertations

When operating in high power applications, power devices dissipate tens or hundreds of watts of power in the form of heat. The ability of the power devices to withstand power and dissipation of heat across the power devices becomes a prominent requirement in designing the power converter. This challenge demands a power converter design to be more effective and consistent which factors in size, cost, weight, power density and reliability. This study aims to propose a gate driver isolated power supply design that can be used in medium voltage applications (e.g., up to 10 kV) while respecting the principle of …

Efficient Routing For Disaster Scenarios In Uncertain Networks: A Computational Study Of Adaptive Algorithms For The Stochastic Canadian Traveler Problem With Multiple Agents And Destinations, Neel Chanchad

Graduate Theses and Dissertations

The primary objective of this research is to develop adaptive online algorithms for solving the Canadian Traveler Problem (CTP), which is a well-studied problem in the literature that has important applications in disaster scenarios. To this end, we propose two novel approaches, namely Maximum Likely Node (MLN) and Maximum Likely Path (MLP), to address the single-agent single-destination variant of the CTP. Our computational experiments demonstrate that the MLN and MLP algorithms together achieve new best-known solutions for 10,715 instances. In the context of disaster scenarios, the CTP can be extended to the multiple-agent multiple-destination variant, which we refer to as …

The Growth And Characterization Of Inn Quantum Dots Using Droplets Epitaxy In Mbe, Malak Refaei

Graduate Theses and Dissertations

III-nitride semiconductor material systems offer great potential for next-generation optoelectronic devices due to their direct bandgaps, which vary from 0.7 eV (InN) to 3.5 eV (GaN) to 6.2 eV (AlN), as well as their other unique properties. InN has gained much less attention than GaN and AlN within this family of semiconductors due to its complicated low-temperature growth. However, the prediction that an InN quantum well on GaN can become a two-dimensional (2D) topological insulator has resulted in expanding the research interest in InN. At the same time, this renewed interest has begun to reveal that the formation of an …

Stream Processor Development Using Multi-Threshold Null Convention Logic Asynchronous Design Methodology, Wassim Khalil

Graduate Theses and Dissertations

Decreasing transistor feature size has led to an increase in the number of transistors in integrated circuits (IC), allowing for the implementation of more complex logic. However, such logic also requires more complex clock tree synthesis (CTS) to avoid timing violations as the clock must reach many more gates over larger areas. Thus, timing analysis requires significantly more computing power and designer involvement than in the past. For these reasons, IC designers have been pushed to nix conventional synchronous (SYNC) architecture and explore novel methodologies such as asynchronous, self-timed architecture. This dissertation evaluates the nominal active energy, voltage-scaled active energy, …

Mitral Valve Imaging And Biomechanics: A Workflow Towards Computational Modeling And Validation, Sam Stephens

Graduate Theses and Dissertations

The mitral valve serves a critical role in healthy cardiac function by ensuring the unidirectional flow of oxygenated blood from the left atrium into the left ventricle. It experiences the highest pressures found within the heart and its closure is the result of a complex interaction of several different structures that, furthermore, are unique to each individual. Despite the valve’s vital role however, the specific function of these constituent structures is not fully understood. This, confounded by its asymmetric, personalized nature, make surgical interventions for the mitral valve far less effective than for its neighboring aortic valve. Efforts to overcome …

Improving Classification In Single And Multi-View Images, Hadi Kanaan Hadi Salman

Graduate Theses and Dissertations

Image classification is a sub-field of computer vision that focuses on identifying objects within digital images. In order to improve image classification we must address the following areas of improvement: 1) Single and Multi-View data quality using data pre-processing techniques. 2) Enhancing deep feature learning to extract alternative representation of the data. 3) Improving decision or prediction of labels. This dissertation presents a series of four published papers that explore different improvements of image classification. In our first paper, we explore the Siamese network architecture to create a Convolution Neural Network based similarity metric. We learn the priority features that …

A Nonlinear-Model-Based High-Bandwidth Current Sensor Design For Switching Current Measurement Of Wide Bandgap Devices, Xia Du, Liyang Du, Yuxiang Chen, Yuqui Wei, Andrea Stratta, H. Alan Mantooth

Electrical Engineering Faculty Publications and Presentations

With the growing adoption of wide bandgap devices in power electronic applications, current sensor design for switching current measurement has become more important. The demands for high accuracy, high bandwidth, low cost, compact size, and galvanic isolation pose significant design challenges. The conventional modeling approach for bandwidth analysis of current transformer sensors assumes that the magnetizing inductance remains constant, which does not always hold true in high-frequency operations. This can result in inaccurate bandwidth estimation and affect the overall performance of the current sensor. To address this limitation, this paper provides a comprehensive analysis of nonlinear modeling and bandwidth, considering …

Reynolds-Averaged Navier-Stokes Cfd Simulation Of High-Speed Boundary Layers, Michael Tullis

Mechanical Engineering Undergraduate Honors Theses

This paper presents an investigation of Reynolds-averaged Navier-Stokes (RANS) turbulence models used in computational fluid dynamics (CFD) simulations of boundary layer flow and heat transfer in high Mach number flows. This study evaluates an industry standard RANS turbulence model (k-omega SST) and a recently proposed modification to that model (Danis and Durbin [1]), and quantifies the accuracy for predicting high Mach number boundary layer flow. The test cases were previously documented by Duan et al. (2018), who used direct numerical simulation (DNS) to calculate boundary layer flow of an ideal gas over a flat plate at freestream Mach numbers ranging …

Investigation Of Dynamic Hybrid Rans-Les Turbulence Modeling For Cfd Simulation Of A Normal Jet In Crossflow, Cole Simmonds

Mechanical Engineering Undergraduate Honors Theses

The jet in crossflow is a canonical flow feature in many natural and engineered systems, ranging from pollutant dispersal in exhaust discharge to film cooling of high-temperature components in modern propulsion systems. The ability to computationally predict the flow features of jets in crossflow accurately and efficiently is therefore important for analysis and design for a wide variety of applications. In this study the capabilities of the dynamic hybrid RANS-LES (DHRL) turbulence modeling technique are investigated and compared to an industry standard Reynolds-averaged Navier-Stokes model (k-omega SST) in order to quantify the accuracy and computational cost of the two approaches. …

The Influence Of Pesticides On Us Corn Production Environmental Impact: A Comparative Life Cycle Assessment Of Dominant Production Practices, Kyle Marinoni Lawrence

Graduate Theses and Dissertations

In recent years there has been increasing interest in reducing agricultural environmental footprints in the United States, particularly for commodity crops like corn grain. Pest management is one aspect of agricultural production that is often identified as having potential for improvement with regard to environmental impact, but there is not a robust body of literature to identify the wide-scale influence of pesticides on yield and environmental impact. In this study, we hypothesized that the use of different classifications of pesticides has a significant impact on the overall environmental impact. To test this, agricultural models were created to represent the dominant …

Understanding And Tuning Magnetism In Van Der Waals Magnetic Compounds, Rabindra Basnet

Graduate Theses and Dissertations

The recently discovered two-dimensional (2D) magnetism has attracted intensive attention due to possible magnetic phenomenon arising from 2D magnetism and their promising potential for spintronics applications. The advances in 2D magnetism have motivated the study of layered magnetic materials, and further enhanced our ability to tune their magnetic properties. Among various layered magnets, tunable magnetism has been widely investigated in metal thiophosphates MPX3. It is a class of magnetic van der Waals (vdW) materials with antiferromagnetic ordering persisting down to atomically thin limit. Their magnetism originates from the localized moments due to 3d electrons in transition metal ions. So, their …

Advanced Cmos Process For Submicron Silicon Carbide (Sic) Device, Niloy Saha

Graduate Theses and Dissertations

Silicon carbide (SiC) is a wide semiconductor material with superior material properties compared to other rival materials. Due to its fewer dislocation defects than gallium nitride and its ability to form native oxides, this material possesses an advantage among wide band gap materials. Despite having several superior properties its low voltage application is less explored. CMOS is extremely important in low voltage areas and silicon is the dominant player in it for the last 50 years where scaling has contributed a major role in this flourishment. The channel length of silicon devices has reached 3 nm whereas SiC is still …