Engineering Commons^™

Proteome Based Development Of Novel Affinity Tail For Immobilized Metal Affinity Chromatography And Hydrophobic Interaction Chromatography, Neha Tiwari

Graduate Theses and Dissertations

At industrial scale, reducing the step in purification and recovery is desired; this not only decreases the cost but also increases the yield. Hydrophobic Interaction Chromatography (HIC) and Immobilized Metal Affinity Chromatography (IMAC) both are not harsh on biological structure or activity of proteins; also both the techniques are economical and therefore a suitable choice at industrial level. This dissertation comprises of three parts. Purpose for the Part I was to identify and characterize Escherichia coli proteins which display affinity towards both IMAC and Hydrophobic Interaction Chromatography (HIC). Co (II) IMAC was chosen as the primary capture step, followed by …

Design And Fabrication Of Nanofluidic Systems For Biomolecule Characterizations, Orain Ansel Hibbert

Graduate Theses and Dissertations

Nanofluidic channel systems were designed and fabricated by combining MEMS microfabrication with AFM nanolithography. In the fabrication process flow, photolithography was first utilized to pattern microfluidic channels and reservoirs on a 4" Pyrex substrate. Subsequently, atomic force microscopy (AFM) based nanolithography was used to mechanically fabricate nanochannels to connect the microreservoirs which formed the inlet and outlet of the nanofluidic system. A Tap190 Diamond-Like Carbon (DLC) AFM tip with a force constant of 48 N/m and a radius of less than 15 nm was used as the nanolithography tool. The resultant nanochannel ranges from 20 to 80 µm in length …

Modeling Of Sic P-Channel Insulated Gate Bipolar Transistors (Igbts), Mahmood Saadeh

Graduate Theses and Dissertations

A new physics-based IGBT compact model has been developed for circuit simulation of silicon (Si) or silicon carbide (SiC) devices. The model accurately predicts the steady-state output, transfer and switching characteristics of the IGBT under a variety of different conditions. This is the first IGBT model to predict the behavior of p-channel SiC IGBTs. Previous work on IGBT models has focused on Si n-channel IGBTs [1-3]. This unified model is not limited to SiC p-channel IGBTs; the user has the option to select between Si or SiC, and n-channel or p-channel, making it the first IGBT model that captures the …

Inventory Models For Intermittent Highly Variable Demand And Policy Parameter Adjustments To Meet Desired Service Level Requirements, Yasin Unlu

Graduate Theses and Dissertations

This dissertation consists of three assays. The first assay examines the robustness of lead time demand models for the continuous review (r;Q) inventory policy. A number of classic distributions as well as distribution selection rules are examined under a wide variety of demand conditions. First, the models are compared to each other by assuming a known demand process and evaluating the errors associated with using a different model. Then, the models are examined using a large sample of simulated demand conditions. Approximation results of inventory performance measures - ready, rate excepted number of backorders and on-hand inventory levels are reported. …

Fabrication Of Horizontal Silicon Nanowires Using A Thin Aluminum Film As A Catalyst, Khaja Hafeezuddin Mohammed

Graduate Theses and Dissertations

Silicon nanowires have been the topic of research in recent years for their significant attention from the electronics industry to grow even smaller electronic devices. The semiconductor industry is built on silicon. Silicon nanowires can be the building blocks for future nanoelectronic devices. Various techniques have also been reported in fabricating the silicon nanowires. But most of the techniques reported, grow vertical silicon nanowires. In the semiconductor industry, integrated circuits are designed and fabricated in a horizontal architecture i.e. the device layout is flat compared to the substrate. When vertical silicon nanowires are introduced in the semiconductor industry, a whole …

Integrated Planning For Rural Rail Transportation, Jeffrey Cohan Gwaltney

Graduate Theses and Dissertations

Population growth in rural areas has led to new interest in rail transportation. Planning a passenger rail system involves numerous difficult decisions, most representing a trade-off between customer service and cost. In this work, we attempt to integrate many of these planning decisions. We consider strategic decisions such as station location and vehicle procurement, as well as tactical issues that include vehicle scheduling. Our integrated model exploits the linear network structure that best suits many rural American communities, including Northwest Arkansas. Due to the intractability of the integrated rail planning problem, we have developed a customized heuristic approach to solve …

Design Of A Low Noise Amplifier For Wireless Sensor Networks, Ting Liu

Graduate Theses and Dissertations

CMOS technology becomes important in Radio Frequency (RF) communication systems which include both a receiver and a transmitter. In a high performance radio receiver, the Low Noise Amplifier (LNA) is the first circuit, and its noise performance dominates the entire receiver. Depending upon the system in which they are used, LNAs can be designed according to various topologies and structures. The LNA needs to have matched input impedance, and at the same time it should amplify the small amplitude input signal without adding too much noise and still have the minimal power consumption. It also needs a good interface with …

Degradation Of Polystyrene Foam Under Radiant Heat Flux, James Butler

Graduate Theses and Dissertations

As the demand for liquefied natural gas has increased, safety concerns about the performance of transport vessels under fire conditions have been raised. Current codes for the sizing of the pressure relief systems require that the vessels are able to withstand an emmissive heat flux of 108kW/m2 and do not take into account the effects of insulation loss due to thermal decomposition of the insulation materials. To address this possible oversight in the current code models were presented to a working group organized by the Society of International Gas Tanker and Terminal Operators Ltd. focusing on the decomposition rate of …

Water Quality Trends For Section 319 Priority Watersheds In Northwest Arkansas, 1997-2010, Bryan William Bailey

Graduate Theses and Dissertations

Northwest Arkansas contains two Section 319 Priority Watersheds that the Arkansas Natural Resources Commission (ANRC) has identified as being impacted by point and nonpoint sources of pollution (i.e., phosphorus, nitrogen, and sediment), and the Arkansas Water Resources Center (AWRC) has monitored the water quality at several sites within these watersheds. Water-quality data has been collected over the last decade within the Illinois River Watershed (HUC #11110103) and the Upper White River Basin (Beaver Reservoir HUC# 11010001), each watershed containing three sampling sites. The Illinois River Watershed sites are located on the Illinois River, Osage Creek, and Ballard Creek, and the …

Photodetectors And Photovoltaic Devices Based On Semiconductor Nanomaterials, Jiang Wu

Graduate Theses and Dissertations

Photodetectors based various nanostructures and plasmon enhanced solar cells are investigated in this dissertation. The motivation of the dissertation rise is driven by urgent need of both high efficiency photodetectors and solar cells.

First, quantum dot infrared photodetectors have been intensely investigated due to their promise in high performance photodetectors. However, the strain-driven growth of quantum dots has hindered the progress of quantum dot photodetectors. The presence of strain in the device presents complexity in designing as well as defects. Therefore, in this project, new designs of quantum dot photodetector structures are presented to improve the control over detection wavelength. …

Investigation Of A Floating Load Buck Dc-Dc Switching Converter, Hong Tan

Graduate Theses and Dissertations

A floating load buck DC-DC switching converter was analyzed, simulated, designed and prototyped. The floating load buck converter is first compared to the conventional buck converter. It was found that both the floating load buck converter and conventional buck converter exhibit similar conversion characteristics despite the differences in the placement of their output inductors. A floating load buck converter was designed to be used as a high-voltage off-line light-emitting diodes (LEDs) driver using a Texas Instruments' TPS92001 controller. Finally, the characteristics of this floating load buck converter LED driver were experimentally examined.

Development Of Spray Cooling For High Heat Flux Electronics, Jeremy Scott Junghans

Graduate Theses and Dissertations

The thermal demands of modern day electronic systems require innovative thermal solutions. Spray cooling has proven to be able to cool heat fluxes orders of magnitude higher than traditional cooling methodologies. This work includes a comparison of spray cooling to standard thermal management methodologies. Key system parameters and considerations are discussed. The properties of available packaging materials and their effect on the reliability of a spray cooled system are presented. Parameters such as fluid temperature, droplet size, fluid velocity and flow rate all directly impact performance and are detailed in this work. Finally, results from of a wide range of …

Design And Implementation Of Metamaterial Based Strain Sensor Using Aperture Coupled Antenna, Michael Brandon Buscher

Graduate Theses and Dissertations

Strain sensors are used to convert the physical measured quantity of strain into an electrical signal suitable for processing by electronic equipment. Traditional strain sensors are comprised of a thin flexible film with a resistive pattern traced on the surface. As the sensor is deformed, the electrical resistance changes proportionally, giving a direct measure of the strain incurred. Metamaterials, particularly split ring resonators (SRR), lend themselves as a valuable tool for sensing applications due to their highly resonant nature and their very narrow bandwidth (high Q-factor). Due to very high field localization effects, they are extremely sensitive to both the …

Modeling And Characterization Of P-Type Silicon Carbide Gate Turn Off Thyristors, Osama Shihadeh Saadeh

Graduate Theses and Dissertations

Silicon carbide (SiC) power semiconductor devices have emerged in the past decade as the most promising technology for next generation power electronic applications ranging for electric vehicles to grid-connected power routing and conversion interfaces. Several devices have been developed, and even some have been released commercially, including diodes, MOSFETs, JFETs, thyristors, gate turn-off thyristors, and IGBTs. The model development, characterization and experimental validation of SiC p-type Gate Turn-off Thyristors (GTO) is presented in this work. The GTO device in this work is being used as part of a SiC-based solid-state fault current limiter under development at the University of Arkansas' …

Laboratory Evaluation Of Dynamic Characterization Methods For Rapid Condition Assessment Of Bridges, Jason Kyle Herrman

Graduate Theses and Dissertations

The objective of this thesis was to devise and refine Structural Health Monitoring methods and the associated quantitative characterization methods with the specific goal of enabling rapid and reliable safety evaluations of bridges following natural or manmade hazards. Presently, the safety and serviceability of these transportation infrastructure assets for use in emergency response and recovery operations are evaluated through on-site visual inspections of individual structures by teams of specially trained engineers or technicians; a process that is manpower-intensive, subjective, and slow. Specifically, the researcher was able to identify and evaluate strategies and procedures for using dynamic testing methods to rapidly …

Understanding The Role Of A Bio-Inspired Surface Modification For Delayed Icing, Clayton Schenk

Graduate Theses and Dissertations

Atmospheric icing event is problematic for outdoor structures because it can damage, slow, impede, and danger general routine. For a wind turbine blade, it can damage, disrupt movement, and cause potentially dangerous ice throw. Anti-icing based on a surface texture is advantageous due to the low cost of maintenance and there is no additional requirement of energy output for preventing the icing problem. This work is based on the biomimicry of the superhydrophobic nature of the lotus leaf, whereas the limited wettability supports the water to flow freely from the surface structure. The phenomenon is based on a morphology and …

A Solid State Nitrogen Gas Generating Chip And Applications For Picosatellites, Kyle Godin

Graduate Theses and Dissertations

A microscale gas generating chip has many applications; in this study, applications relating to picosatellites have been considered. Cube satellites, a type of picosatellite, are of mass around one kilogram and side length 10cm x 10cm x 10cm. Their launches are becoming more numerous since their debut ten years ago. Their low cost and deployment system makes space accessible to agencies hitherto barred from it, such as universities and small governments. However, their power, mass, and volume budget is extremely tight. A microscale gas chip could compete with other designs for attitude control devices, most not flown yet as cube …

On The Complexity Of Grid Coloring, Daniel Christopher Apon

Graduate Theses and Dissertations

This thesis studies problems at the intersection of Ramsey-theoretic mathematics, computational complexity, and communication complexity. The prototypical example of such a problem is Monochromatic-Rectangle-Free Grid Coloring. In an instance of Monochromatic-Rectangle-Free Grid Coloring, we are given a chessboard-like grid graph of dimensions n and m, where the vertices of the graph correspond to squares in the chessboard, and a number of allowed colors, c. The goal is to assign one of the allowed colors to each vertex of the grid graph so that no four vertices arranged in an axis-parallel rectangle are colored monochromatically. Our results include: 1. A conditional, …

File System Simulation: Hierarchical Performance Measurement And Modeling, Hai Quang Nguyen

Graduate Theses and Dissertations

File systems are very important components in a computer system. File system simulation can help to predict the performance of new system designs. It offers the advantages of the flexibility of modeling and the cost and time savings of utilizing simulation instead of full implementation. Being able to predict end-to-end file system performance against a pre-defined workload can help system designers to make decisions that could affect their entire product line, involving several million dollars of investment. This dissertation presents detailed simulation-based performance models of the Linux ext3 file system and the PVFS parallel file system. The models are developed …

Applying Inventory Control Practices Within The Sisters Of Mercy Health Care Supply Chain, Server Apras

Graduate Theses and Dissertations

This research lays a foundation for the better understanding of the application and acceptance of more advanced inventory control practices within the health care supply chain. The demand characteristics and optimal control policies for pharmaceutical items within a multi-echelon provider network are examined within the framework of a case study. Demand forecasting algorithms were applied to forecast demand for inventory control procedures. A spreadsheet-based inventory planning tool was used to minimize the inventory holding and ordering costs subject to fill rate constraints. The costs of inventory control models are compared to the current ordering and inventory control strategies to document …

Evaluating The Capacity Of A Proton Therapy Facility, Ridvan Gedik

Graduate Theses and Dissertations

A relatively new consideration in proton therapy planning is the requirement that the mix of patients treated satisfy desired percentages. Since it is very dicult to satisfy an integer number of patients in light of these requirements, deviations from patient mix preferences and their impacts on operational capabilities are of particular interest to healthcare planners. Therefore, we propose a bicriteria mathematical programming model that determines an outpatient schedule maximizing the number of fractions and minimizing the deviations from the patient mix ratios over the planning horizon. The tradeos between the two objectives are identied through analysis of ecient frontiers. Our …

An Empirical Investigation Of Supply Chain Excellence In Healthcare, Brian Keith Smith

Graduate Theses and Dissertations

This research is motivated by opportunities to improve the cost and quality of healthcare delivery through improved supply chain processes. This research assesses the quality of the healthcare supply chain and identifies factors that are driving supply chain excellence among organizations in the healthcare industry. The first objective of this research is to assess the state of quality measurement in the healthcare supply chain. The achievement of this first objective is presented in Chapter 3 of this dissertation in the form of a manuscript accepted for publication in The Quality Management Journal. The second research objective is to develop …

Two Dimensional Modeling Of Wind Effects On A Bridge Section Using Finite Difference Method, Jessica Carreiro

Civil Engineering Undergraduate Honors Theses

Wind effects on long span bridges are a major concern for bridge design. Wind acts as a dynamic load on the bridge deck causing the bridge to react in ways not accounted for in static load design. Attention to these effects increased tremendously after famous bridge collapses, such as the Tacoma Narrows Bridge in 1940. Due to this collapse and others, engineers were made painfully aware that wind phenomena, such as flutter and vortex shedding, can cause major structural damage if not considered in the design process. The solution for many years since has been to conduct wind tunnel tests …

Plasmonic Effect On The Photoluminescence Of Inas Quantum Dot Nanostructures, David Fryauf

Electrical Engineering Undergraduate Honors Theses

New materials for thin film photovoltaic applications are being explored worldwide, and one of the most popular new implementations is the introduction of an intermediate band gap in the semiconductor energy structure. Careful manipulation of semiconductor lattice material can form nanostructures such as quantum dots, which can be tuned to control specific intermediate energy levels. The introduction of an intermediate band in photovoltaic devices has a theoretical potential sunlight-toelectricity efficiency of roughly 63%. However, a specific material challenge of these thin film devices is limited absorption of long wavelengths of light. To increase absorption of the sun's visible spectrum, plasmonic …

An Expressive Vocal Midi Controller, Brady Hurlburt

Electrical Engineering Undergraduate Honors Theses

The choice of controller often characterizes the performance obtained from an electronic instrument. Controllers exist that allow electronic musicians to mimic the expressive qualities of keyboard, wind, string, and percussion instruments, but vocalists have been largely neglected. To fill this need, a realtime software vocal MIDI controller named Grove is developed and demonstrated. Grove's pitch and time analyses are shown to be accurate, and it has mappable control signals that go beyond the capabilities of previous audio-to-MIDI converters to facilitate an expressive performance. Grove's source code is available under the GNU GPL v3 license.

Showcase For The Advantages Of Asynchronous Vs. Synchronous Circuits, Justin Roark

Electrical Engineering Undergraduate Honors Theses

Synchronous circuits dominate the semiconductor industry, but asynchronous circuitry is becoming more popular and will continue to do so, as evidenced by the International Technology Roadmap for Semiconductors. Asynchronous circuits, when compared to synchronous circuits, display tolerance to supply voltage and temperature variation. The goal of this project is to demonstrate these two advantages. The project will compare two microcontrollers, a synchronous 8051 and an asynchronous 8031, which will both play a song under various stresses. Note that an 8031 and 8051 are the same, except for the 8051 includes an on-chip instruction memory, whereas the 8031's is off-chip. When …

Reducing Energy Usage Of Null Convention Logic Circuits Using Null Cycle Reduction Combined With Supply Voltage Scaling, Brett Sparkman

Electrical Engineering Undergraduate Honors Theses

The NULL Cycle Reduction (NCR) technique can be used to improve the performance of the NULL Convention Logic (NCL) circuit at the expense of power and area. However, by decreasing the supply voltage of certain components, the power of the NCR circuit can be reduced. Since NCR has increased performance, it could be possible to decrease the power while maintaining the original performance of the circuit. To verify this, the NCR circuit will be implemented using a 4-bit by 4-bit dual-rail multiplier as the test circuit. This circuit will be simulated in ModelSim to ensure functionality, synthesized into a Verilog …

Development Of A Ram Shared Service Tool For The Service Availability Of On-Board And Trackside Systems, Bailey Frazier

Industrial Engineering Undergraduate Honors Theses

A decision-support tool designed specifically to be used by technical specialists is an aid that would be helpful to many different companies, departments and projects – regardless of industry. With the intent of making manual processes quicker, less error-prone, and more userfriendly, decision-support tools are becoming more desired as they grow increasingly more common in the business world today.
The decision-support tool created for the purpose of this project is not an exception to any of these reasons. The ALSTOM Transport Information Solutions Reliability, Availability, and Maintainability (RAM) Shared Service Team bears the burden and tedious process of working with …

Re-Estimating And Remodeling General Aviation Operations, Ryan Black

Industrial Engineering Undergraduate Honors Theses

The objective of this project is to understand the usual or “acceptable” characteristics of general aviation flights and airports so that unusual activity can be detected, analyzed, and resolved. To do this, a quality control model may be built to determine whether an airport is at high risk for a terrorist attack. For an appropriate model to be built there must be an adequate amount of data that describes the general aviation airport and its operations. In order to facilitate this data the general aviation industry must “continue to improve intelligence and information sharing (Homeland Security Advisory Council 2008).” This …

Extraction Of Butanol By Continuous Pervaporation Of A Two-Stage Fermentation, Kelly Meek

Chemical Engineering Undergraduate Honors Theses

Within this research a fermentation broth is used that has been developed first from the continuous fermentation of algal sugars to organic acids with Clostridium tyrobutyricum, followed by the continuous fermentation of the organic acids to butanol using Clostridium saccharoperbutylacetonium. The two-stage fermentation has the potential to increase the butanol selectivity from 60% by weight with the traditional ABE process to as high as 100% with the 2-stage process.