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Novel Locomotion Methods In Magnetic Actuation And Pipe Inspection, Adam Cox
Novel Locomotion Methods In Magnetic Actuation And Pipe Inspection, Adam Cox
Mechanical Engineering Research Theses and Dissertations
There is much room for improvement in tube network inspections of jet aircraft. Often, these inspections are incomplete and inconsistent. In this paper, we develop a Modular Robotic Inspection System (MoRIS) for jet aircraft tube networks and a corresponding kinematic model. MoRIS consists of a Base Station for user control and communication, and robotic Vertebrae for accessing and inspecting the network. The presented and tested design of MoRIS can travel up to 9 feet in a tube network. The Vertebrae can navigate in all orientations, including smooth vertical tubes. The design is optimized for nominal 1.5" outside diameter tubes. We …
Resistive Pulse Sensing Of Protein Unfolding And Transport In Solid-State Nanopores, Jugal Saharia
Resistive Pulse Sensing Of Protein Unfolding And Transport In Solid-State Nanopores, Jugal Saharia
Mechanical Engineering Research Theses and Dissertations
Solid-state nanopore sensors have attracted considerable attraction as a tool for solution-based single-molecule studies and have been successfully utilized for characterization of biomolecules such as nucleic acids, proteins, glycans, viruses, etc. Among these, characterization of proteins has been more challenging due to their charge heterogeneity and the complex energy landscape associated with different protein conformations. Presented in this thesis is the fabrication of solid-state nanopores and their application for characterizing proteins and understanding their transport through nanopores. Fabrication of nanometer-sized pores in SixNy membranes was achieved using the conventional controlled dielectric breakdown method as well as a …
Closed-Loop Brain-Computer Interfaces For Memory Restoration Using Deep Brain Stimulation, David Xiaoliang Wang
Closed-Loop Brain-Computer Interfaces For Memory Restoration Using Deep Brain Stimulation, David Xiaoliang Wang
Electrical Engineering Theses and Dissertations
The past two decades have witnessed the rapid growth of therapeutic brain-computer interfaces (BCI) targeting a diversity of brain dysfunctions. Among many neurosurgical procedures, deep brain stimulation (DBS) with neuromodulation technique has emerged as a fruitful treatment for neurodegenerative disorders such as epilepsy, Parkinson's disease, post-traumatic amnesia, and Alzheimer's disease, as well as neuropsychiatric disorders such as depression, obsessive-compulsive disorder, and schizophrenia. In parallel to the open-loop neuromodulation strategies for neuromotor disorders, recent investigations have demonstrated the superior performance of closed-loop neuromodulation systems for memory-relevant disorders due to the more sophisticated underlying brain circuitry during cognitive processes. Our efforts are …