Engineering Commons^™

Backfolding Of Wormlike Chains Confined In Nanochannels, Abhiram Muralidhar, Douglas R. Tree, Kevin D. Dorfman

Faculty Publications

Using pruned-enriched Rosenbluth method (PERM) simulations of a discrete wormlike chain model, we provide compelling evidence in support of Odijk’s prediction of two distinct Odijk regimes for a long wormlike chain confined in a nanochannel. In both cases, the chain of persistence length lp is renormalized into a series of deflection segments of characteristic length D2/3lp1/3, where D is the channel size. In the first (classic) Odijk regime, these deflection segments are linearly ordered. In the second Odijk regime, thin, long wormlike chains can backfold at a length scale quantified by the global persistence length. We …

Nonlinear Modeling, Estimation And Predictive Control In Apmonitor, John Hedengren, Reza Asgharzadeh Shishavan, Kody M. Powell, Thomas F. Edgar

Faculty Publications

This paper describes nonlinear methods in model building, dynamic data reconciliation, and dynamic optimization that are inspired by researchers and motivated by industrial applications. A new formulation of the ℓ₁-norm objective with a dead-band for estimation and control is presented. The dead-band in the objective is desirable for noise rejection, minimizing unnecessary parameter adjustments and movement of manipulated variables. As a motivating example, a small and well-known nonlinear multivariable level control problem is detailed that has a number of common characteristics to larger controllers seen in practice. The methods are also demonstrated on larger problems to reveal algorithmic …

Investigating The Release Mechanism Of Calcein From Eliposomes At Higher Temperatures, Ghaleb A. Husseini, William G. Pitt, Jacob B. Williams, Marjan Javadi

Faculty Publications

Numerous nanocarriers are currently being investigated as drug delivery vehicles for transporting chemotherapeutics to cancer cells. Our research group has recently synthesized a new generation of echogenic liposomes based on the concept of encapsulating one or more nanoemulsion droplets inside a liposome (called an “eLiposome”). The concept is to use a nanoemulsion droplet with a low boiling point near body temperature, thus requiring only a small acoustic nudge to vaporize the droplet from liquid to gas and break open the eLiposome, thus releasing its contents. The purpose of this note is twofold. First, we wanted to show experimentally that eLiposomes …

Compliant Mechanisms For Deployable Space Systems, Shannon Alisa Zirbel

Theses and Dissertations

The purpose of this research is to develop fundamentals of compliant mechanisms in deployable space systems. The scope was limited to creating methods for thick origami, developing compliant deployable solar arrays, and developing methods for stowing and deploying the arrays. The research on actuation methods was focused on a one-time deployment of the array. Concepts for both passive and active actuation were considered. The primary objective of this work was to develop approaches to accommodate thickness in origami-based deployable arrays with a high ratio of deployed-to-stowed diameter. The HanaFlex design was derived from the origami flasher model and is developed …

Design And Analysis Of Robotically-Controlled Minimally Invasive Surgical Instruments, Jordan D. Tanner

Theses and Dissertations

Robot-assisted minimally invasive surgery is used to perform intricate surgical tasks through small incisions using long, slender instruments. The miniaturization of these instruments is advantageous to both surgeon and patient because smaller instruments reduce trauma to surrounding tissue, decrease patient recovery times, and can be used in confined spaces otherwise inaccessible using larger instruments. However, miniaturization of existing designs is limited by friction between moving parts, the volume occupied by the end effector, and manufacturing and assembly constraints. The objective of this work is to develop and analyze concepts that can be used in robot-assisted needlescopic surgery. The concepts are …

Gasification Of Biomass, Coal, And Petroleum Coke At High Heating Rates And Elevated Pressure, Aaron D. Lewis

Theses and Dissertations

Gasification is a process used to convert any carbonaceous species through heterogeneous reaction to obtain the desired gaseous products of H2 and CO which are used to make chemicals, liquid transportation fuels, and power. Both pyrolysis and heterogeneous gasification occur in commercial entrained-flow gasifiers at pressures from 4 to 65 atm with local gas temperatures as high as 2000 °C. Many gasification studies have been performed at moderate temperatures, heating rates, and pressures. In this work, both pyrolysis and char gasification experiments were performed on coal, petroleum coke, and biomass at conditions pertinent to commercial entrained-flow gasifiers. Rapid biomass pyrolysis …

A Solid-State Ion Detector For Use In Portable Mass Spectrometry, Sadek Salman Sabbah

Theses and Dissertations

Mass spectrometry has long been used as a scientific tool in a wide variety of applications. A portable mass spectrometer would make many of these applications faster and more efficient. One of the key components of a mass spectrometer is its ion detection system; to make a mass spectrometer portable, this system must be small and involve as few components as possible. Single ion detection has been achieved through several methods, nearly all of which are well-known and understood. These methods, however, often require bulky vacuum and/or cooling systems in order to achieve high sensitivity. An ion detection system that …

Preparation Of Active, Stable Supported Iron Catalysts And Deactivation By Carbon Of Cobalt Catalysts For Fischer-Tropsch Synthesis, Kamyar Keyvanloo

Theses and Dissertations

The first half of this dissertation reports the development of supported Fe FT catalysts including the effects of various, carefully chosen preparation methods on the performance of alumina-supported iron/copper/potassium (FeCuK/Al2O3); it was determined that non-aqueous slurry impregnation and co-impregnation yielded catalysts with activities as high as any reported in the literature. Furthermore, the effects of support properties including pore size, hydroxyl group concentration, and support stabilizer were investigated for FeCuK/Al2O3 catalysts containing 20 or 40% Fe. For the first time, we report the performance of a supported Fe FT catalyst that is not only more active and stable than any …

Design Considerations In The Development And Actuation Of Origami-Based Mechanisms, Eric W. Wilcox

Theses and Dissertations

Origami-based mechanisms have unique characteristics that make them attractive for engineering applications. However, origami-based design is still a developing area of design. Continued work to increase general understanding of key design parameters specific to origami-based mechanisms will increase the ability of designers to capture the potential benefits of origami-based mechanisms. This thesis presents a fundamental study of origami to assist designers in gaining a stronger understanding of the key parameters and capabilities of origami-based mechanisms. As a starting point a study of fundamental motions in action origami models (those that exhibit motions in their folded state) is presented to explore …

Fault Detection For Unmanned Aerial Vehicles With Non-Redundant Sensors, Brandon Jeffrey Cannon

Theses and Dissertations

To operate, autonomous systems of necessity employ a variety of sensors to perceive their environment. Many small unmanned aerial vehicles (UAV) are unable to carry redundant sensors due to size, weight, and power (SWaP) constraints. Faults in these sensors can cause undesired behavior, including system instability. Thus, detection of faults in these non-redundant sensors is of paramount importance.The problem of detecting sensor faults in non-redundant sensors on board autonomous aircraft is non-trivial. Factors that make development of a solution difficult include both an inability to perfectly characterize systems and sensors as well as the SWaP constraints inherent with small UAV. …

Particle Dispersion In Homogeneous Turbulence Using The One-Dimensional Turbulence Model, Guangyuan Sun, David O. Lignell, John C. Hewson, Craig R. Gin

Faculty Publications

Lagrangian particle dispersion is studied using the one-dimensional turbulence (ODT) model in homogeneous decaying turbulence configurations. The ODT model has been widely and successfully applied to a number of reacting and nonreacting flow configurations, but only limited application has been made to multiphase flows. Here, we present a version of the particle implementation and interaction with the stochastic and instantaneous ODT eddy events. The model is characterized by comparison to experimental data of particle dispersion for a range of intrinsic particle time scales and body forces. Particle dispersion, velocity, and integral time scale results are presented. The particle implementation introduces …

Development Of Ultrasound Sensitive Eliposomes Containing Doxorubicin For Drug Delivery, Chung-Yin Lin, William G. Pitt, Kuo-Chen Wei

Faculty Publications

Aims: A novel nanocarrier was formulated by remote loading of doxorubicin (Dox) into a dipalmitoylphosphatidylcholine (DPPC) liposome that also contains various perfluorocarbon (PFC) droplets within its aqueous interior. It was shown that Dox can be loaded to a level of up to 67% into these large unilamellar vesicles composed of DPPC and cholesterol by employing a transmembrane pH gradient technique.

Methods: The different encapsulation efficiencies for these eLipoDox constructs of differing PFC composition are 45.5% (PFC5), 31.5% (PFC6) and 66.7% (PFC5/PFC6 mixture, PFCm). At 30 seconds of insonation, the eLipoDox formulation with PFCm droplets appeared to release more Dox than …

Characterization Of Postural Tremor In Essential Tremor Using A Seven-Degree-Of-Freedom Model, Daniel William Geiger

Theses and Dissertations

Essential Tremor (ET), a condition characterized by postural and kinetic tremor in the upper limbs, is one of the most prevalent movement disorders. While pharmaceutical and surgical treatment options exist, they are not ideal. Assistive devices have the potential to provide relief to patients but are largely unexplored for ET. Furthermore, prior characterizations of essential tremor have focused on endpoint tremor and provide insufficient detail for designing such a device. We propose and demonstrate a novel method for characterizing essential tremor in the 7 proximal degrees of freedom (DOF) of the upper limb in various postures. In addition, we provide …

Application Of Variation Of Parameters To Solve Nonlinear Multimode Heat Transfer Problems, Travis J. Moore

Theses and Dissertations

The objective of this work is to apply the method of variation of parameters to various direct and inverse nonlinear, multimode heat transfer problems. An overview of the general method of variation of parameters is presented and applied to a simple example problem. The method is then used to obtain solutions to three specific extended surface heat transfer problems: 1. a radiating annular fin, 2. convective and radiative exchange between the surface of a continuously moving strip and its surroundings, and 3. convection from a fin with temperature-dependent thermal conductivity and variable cross-sectional area. The results for each of these …

Co-Firing Biomass With Biogas In Cookstoves With A Fan, Manil Poudyal

Theses and Dissertations

Co-firing is a combustion process in which more than one type of fuel is used. In many cases, co-firing reduces fuel costs and/or reduces the environmental impact. The objective of this research was to test the hypothesis that adding biogas to be co-fired with biomass in a traditional cookstove reduces indoor air pollution and increases the combustion efficiency. The impact of co-firing on indoor air pollution is assessed by comparing the concentrations of carbon monoxide and particulate matter in the exhaust stream of a co-fired cookstove to a cookstove fueled with biomass alone. The concentrations of each of these pollutants …

Investigating The Stability Of Eliposomes At Elevated Temperatures, Ghaleb A. Husseini, William G. Pitt, Marjan Javadi

Faculty Publications

eLiposomes encapsulate a perfluorocarbon nanoemulsion droplet inside a liposome. Ultrasound is then used as a trigger mechanism to vaporize the perfluorocarbon, break the liposome, and release the desired drug to the tumor tissue. The purpose of this research is to show that eLiposomes synthesized using perfluoropentane are stable above the normal boiling point of the perfluoropentane and at body temperature and thus has potential for use in vivo. Experiments involving the release of fluorescent calcein molecules were performed on eLiposomes to measure the release of calcein at various temperatures in the absence of ultrasound. Results showed that eLiposomes are stable …

Investigating The Stability Of Eliposomes At Elevated Temperatures, Ghaleb A. Husseini, William G. Pitt, Marjan Javadi

Faculty Publications

eLiposomes encapsulate a perfluorocarbon nanoemulsion droplet inside a liposome. Ultrasound is then used as a trigger mechanism to vaporize the perfluorocarbon, break the liposome, and release the desired drug to the tumor tissue. The purpose of this research is to show that eLiposomes synthesized using perfluoropentane are stable above the normal boiling point of the perfluoropentane and at body temperature and thus has potential for use in vivo. Experiments involving the release of fluorescent calcein molecules were performed on eLiposomes to measure the release of calcein at various temperatures in the absence of ultrasound. Results showed that eLiposomes are stable …

Piv Measurements Of Turbulent Flow In A Rectangular Channel Over Superhydrophobic Surfaces With Riblets, Richard Mark Perkins

Theses and Dissertations

In this thesis I investigate characteristics of turbulent flow in a channel where one of the walls has riblets, superhydrophobic microribs, or a hybrid surface with traditional riblets built on a superhydrophobic microrib surface. PIV measurements are used to find the velocity profile, the turbulent statistics, and shear stress profile in the rectangular channel with one wall having a structured test surface. Both riblets and superhydrophobic surfaces can each provide a reduction in the wall shear stress in a turbulent channel flow. Characterizing the features of the flow using particle image velocimetry (PIV) is the focus of this research. Superhydrophobicity …

A Simple Solution Method For The Blade Element Momentum Equations With Guaranteed Convergence, Andrew Ning

Faculty Publications

The blade element momentum equations, though conceptually simple, can be challenging to solve reliably and efficiently with high precision. These requirements are particularly important for efficient rotor blade optimization that utilizes gradient-based algorithms. Many solution approaches exist for numerically converging the axial and tangential induction factors. These methods all generally suffer from a lack of robustness in some regions of the rotor blade design space, or require significantly increased complexity to promote convergence. The approach described here allows for the blade element momentum equations to be parameterized by one variable: the local inflow angle. This reduction is mathematically equivalent, but …

Extended Formation Flight At Transonic Speeds, Andrew Ning, Ilan Kroo, Michael Aftosmis, Marian Nemec, James Kless

Faculty Publications

Aircraft flown in formation can realize significant reductions in induced drag by flying in regions of wake upwash. However, most transports fly at transonic speeds where the impact of compressibility on formation flight is not well understood. This study utilizes an Euler solver to analyze the inviscid aerodynamic forces and moments of transonic wing/body configurations flying in a two-aircraft formation. Formations with large streamwise separation distances (10-50 wingspans) are considered.

This work indicates that compressibility-related drag penalties in formation flight may be eliminated by slowing 2-3% below the nominal out-of-formation cruise Mach number (either at fixed lift coefficient or fixed …

Compliant Joints Suitable For Use As Surrogate Folds, Isaac L. Delimont

Theses and Dissertations

Origami-inspired design is an emerging field capable of producing compact and efficient designs. The object of a surrogate fold is to provide a fold-like motion in a non-paper material without undergoing yielding. Compliant mechanisms provide a means to achieve these objectives as large deflections are achieved. The purpose of this thesis is to present a summary of existing compliant joints suitable for use as surrogate folds. In doing so, motions are characterized which no existing compliant joint provides. A series of compliant joints is proposed which provides many of these motions. The possibility of patterning compliant joints to form an …

Digital Back End Development And Interference Mitigation Methods For Radio Telescopes With Phased-Array Feeds, Richard Allen Black

Theses and Dissertations

The Brigham Young University (BYU) Radio Astronomy group, in collaboration with Cornell University, the University of Massachusetts, and the National Radio Astronomy Observatory (NRAO), have in recent years developed and deployed PAF systems that demonstrated the advantages of PAFs for astronomy. However, these systems lacked the necessary bandwidth and acquisition times to be scientifically viable. This thesis outlines the development of a 20-MHz bandwidth system that can acquire for much longer periods of time and across much larger bandwidths than previous BYU systems. A report of the deployment of this system on the 305-meter reflector at the Arecibo Observatory in …

Implementing Dubins Airplane Paths On Fixed-Wing Uavs, Timothy Mclain, Randall W. Beard, Mark Owen

Faculty Publications

A well-known path-planning technique for mobile robots or planar aerial vehicles is to use Dubins paths, which are minimum-distance paths between two configurations subject to the constraints of the Dubins car model. An extension of this method to a three-dimensional Dubins airplane model has recently been proposed. This chapter builds on that work showing a complete architecture for implementing Dubins airplane paths on small fixed-wing UAVs. The existing Dubins airplane model is modified to be more consistent with the kinematics of a fixed-wing aircraft. The chapter then shows how a recently proposed vector-field method can be used to design a …

Communication: Using Multiple Tethers To Stabilize Proteins On Surfaces, Brandon K. Loong, Thomas A. Knotts Iv

Faculty Publications

Protein surface interactions are important in many applications in biotechnology including protein arrays, but these technologies have not lived up to their transformative potential because it is difficult to attach proteins to surfaces in a manner that preserves function and theoretical understanding of the relevant phenomena remains limited. Here is reported the effect of using multiple tethers to attach a protein (lysozyme) to a surface and the effects on the structure and stability of the molecule. The simulations show how using two tethers can drastically change the folding mechanism such that a protein that is initially unstable and inactive when …

Conflict Management And Model Consistency In Multi-User Cad, Ammon Ikaika Hepworth

Theses and Dissertations

The NSF Center for e-Design, Brigham Young University (BYU) site has re-architected Computer Aided Design (CAD) tools, enabling multiple users to concurrently create, modify and view the same CAD part or assembly. This technology allows engineers, designers and manufacturing personnel to simultaneously contribute to the design of a part or assembly in real time,enabling parallel work environments within the CAD system. Multi-user systems are only as robust and efficient as their methods for managing conflicts and preserving model consistency. Conflicts occur in multi-user CAD when multiple users interoperate with the same or dependent geometry. Some conflicts can lead to model …

System Identification Of An Unmanned Tailsitter Aircraft, Nathan W. Edwards

Theses and Dissertations

The motivation for this research is the need to improve performance of the autonomous flight of a tailsitter UAV. Tailsitter aircraft combine the hovering and vertical take-off and landing capability of a rotorcraft with the long endurance flight capability of a fixed-wing aircraft. The particular aircraft used in this research is the V-Bat, a tailsitter UAV with a conventional wing and the propeller and control surfaces located within a ducted-fan tail assembly. This research focuses on identifying the models and parameters of the V-Bat in hover and level flight as a basis for the design of the control systems for …

Sediment Transport Conditions Near Culverts, Kyle Jay Rowley

Theses and Dissertations

Relatively little work has been done to understand how coarse grained sediments behave near culverts. Particularly for embedded culverts, sediment transport must be understood to achieve sustainable culvert designs for aquatic organism passage and peak discharge requirements. Several culvert sites in the Wasatch Mountains of Utah were studied through the spring flood season of 2014. Data obtained from the culvert sites were used to create numerical models with the Sedimentation and River Hydraulics Two-Dimensional model. The field sites and numerical model were used to study deposition of sediments at the entrance to culverts, sediment replenishment inside culverts, and lateral fining …

Catalytic Performance Of An Iron-Based Catalyst In Fischer–Tropsch Synthesis, Majid Sarkari, Farhad Fazlollahi, Hossein Ajamein, Hossein Atashi, William C. Hecker, Larry L. Baxter

Faculty Publications

This paper documents the performance and kinetics of an iron/manganese oxide catalyst in a fixed-bed reactor by Fischer–Tropsch synthesis (FTS) under conditions favoring the formation of gaseous and liquid hydrocarbons (P: 1–12 bar; T: 513–543 K; H2/CO:1, 1.5, 2 mol/mol; gas hourly space velocity: 4200–7000 cm3 (STP)/h/gcat). Based on the hypothesis that water inhibits the intrinsic FTS reaction rate, eight kinetic models are considered: six variations of the Langmuir–Hinshelwood–Hougen–Watson representation and two empirical power-law models. The kinetic expression/mechanism that most precisely fits the data assumes the following: (1) CO dissociation is reversible and does not involve hydrogen; (2) all hydrogenation …

Refinement And Characterization Of Synthetic Vocal Fold Models, Shelby Charisse Ward

Theses and Dissertations

Understanding vocal fold mechanics is an integral part of voice research and synthetic vocal fold models are an essential tool in characterizing vocal fold mechanics. These models contain multiple layers with varying stiffness, much like human vocal folds. The purpose of this thesis is to improve the current models and modeling techniques, as well as investigate the impact of asymmetry on model vibration. A new design for an MRI-based model is detailed. This model has a more realistic geometry than the simplified models and mimics some of the vibratory characteristics observed in human vocal folds. The MRI-based model was used …

Source Apportionment Of Wastewater Using Bayesian Analysis Of Fluorescence Spectroscopy, Daniel B. Blake

Theses and Dissertations

This research uses Bayesian analysis of fluorescence spectroscopy results to determine if wastewater from the Heber Valley Special Service District (HVSSD) lagoons in Midway, UT has seeped into the adjacent Provo River. This flow cannot be directly measured, but it is possible to use fluorescence spectroscopy to determine if there is seepage into the river.Fluorescence spectroscopy results of water samples obtained from HVSSD lagoons and from upstream and downstream in the Provo River were used to conduct this statistical analysis. The fluorescence 'fingerprints' for the upstream and lagoon samples were used to deconvolute the two sources in a downstream sample …