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Full-Text Articles in Engineering
Improved Manufacturing Methods Of Bovine Femur Samples For Ultrasonic Testing And Assessment Of Materials Through Contract Angle Measurement, Kevin Mathew Lopez Galang
Improved Manufacturing Methods Of Bovine Femur Samples For Ultrasonic Testing And Assessment Of Materials Through Contract Angle Measurement, Kevin Mathew Lopez Galang
Biomedical Engineering
At California Polytechnic State University of San Luis Obispo (Cal Poly), the Biomedical Engineering department (BMED) requires its students to take the course listed as “BMED 420: Principles of Biomaterial Designs.” BMED 420 has a required laboratory section every week throughout the duration of the course that is meant to be a supplemental tool for learning. During the lab sections, students perform experiments and exercises that are currently being implemented in the industry. Despite accuracy of the methods and experiments relative to their use in the industry, there is always room for improvement. The objective of this project will illustrate …
Roles Of Polymer Crosslinking Density And Crystallinity In Regulating Surface Characteristics And Pre-Osteoblastic Mc3t3 Cell Behavior, Kan Wang
Doctoral Dissertations
This dissertation presents material design strategies to investigate cell-biomaterial interactions on specific biocompatible polymers and polymer blends by using mouse pre-osteoblastic MC3T3 cells aiming for potential applications in bone tissue engineering. Chapter 1 reviews some related background knowledge including polymeric biomaterials for tissue engineering, cell-biomaterial interaction, synthetic photo-crosslinkable and degradable polymers, and the effect of surface features on osteoblast cell responses. Chapter 2 presents photo-crosslinkable composites of poly(propylene fumarate) (PPF), an injectable and biodegradable polyester, and methacryl-polyhedral oligomeric silsesquioxane (mPOSS), which has eight methacryl groups tethered with a cage-like hybrid inorganic-organic nanostructure, for bone tissue engineering applications. Blending mPOSS with …
Preparation And Characterisation Of Graft Biopolymer To Improve Sustained Release Property, Ajit Behera
Preparation And Characterisation Of Graft Biopolymer To Improve Sustained Release Property, Ajit Behera
Ajit Behera
In the present piece of research work focuses on grafting Acrylic acid with HPMC to obtain copolymers with improved properties, biodegradable and biocompatible that will be used as hydrogel or water absorbing polymers. To develop a prolong release activity drug delivery system for the medication purpose to enhance drug activity and reduce the frequency of dose via this hydrogel. A novel HPMC-g- acrylic acid hydrogel was prepared by in-situ emulsifier free emulsion polymerization using benzyl peroxide as an initiator through 1-stage grafting. Acrylic Acid could intercalate into layers of HPMC and form graft composites through in situ graftpolymerization with acrylic …
Development Of Cationic Polymer Coatings To Regulate Foreign-Body Responses, Minglin Ma, Wendy F. Liu, Paulina S. Hill, Kaitlin M. Bratlie, Daniel J. Siegwart, Justin Chin, Miri Park, Joao Guerreiro, Daniel G. Anderson
Development Of Cationic Polymer Coatings To Regulate Foreign-Body Responses, Minglin Ma, Wendy F. Liu, Paulina S. Hill, Kaitlin M. Bratlie, Daniel J. Siegwart, Justin Chin, Miri Park, Joao Guerreiro, Daniel G. Anderson
Kaitlin M. Bratlie
A library of cationic polymers, poly(beta-amino alcohols) with a great chemical diversity are synthesized using combinatorial polymerization. These polymers, when immobilized on a surface, drastically affect the behavior of monocyte/macrophage cells in vitro and early inflammatory reactions in vivo. Certain polymers are found capable of mitigating the foreign-body responses.
Electrochemical Investigation Of Chromium Nanocarbide Coated Ti-6al-4v And Co-Cr-Mo Alloy Substrates, Viswanathan Swaminathan, Haitong Zeng, Daniel Lawrynowicz, Zongtao Zhang, Jeremy L. Gilbert
Electrochemical Investigation Of Chromium Nanocarbide Coated Ti-6al-4v And Co-Cr-Mo Alloy Substrates, Viswanathan Swaminathan, Haitong Zeng, Daniel Lawrynowicz, Zongtao Zhang, Jeremy L. Gilbert
Biomedical and Chemical Engineering - All Scholarship
This study investigated the electrochemical behavior of chromium nano-carbide cermet coating applied on Ti–6Al–4V and Co–Cr–Mo alloys for potential application as wear and corrosion resistant bearing surfaces. The cermet coating consisted of a highly heterogeneous combination of carbides embedded in a metal matrix. The main factors studied were the effect of substrate (Ti–6Al–4V vs. Co–Cr–Mo), solution conditions (physiological vs. 1 M H2O2 of pH 2), time of immersion (1 vs. 24 h) and post coating treatments (passivation and gamma sterilization). The coatings were produced with high velocity oxygen fuel (HVOF) thermal spray technique at atmospheric conditions to …