Engineering Commons^™

Detection Of Leukocytes Stained With Acridine Orange Using Unique Spectral Features Acquired From An Image-Based Spectrometer, Courtney J. Hunter

Biomedical Engineering Undergraduate Honors Theses

A leukocyte differential count can be used to diagnosis a myriad blood disorders, such as infections, allergies, and efficacy of disease treatments. In recent years, attention has been focused on developing point-of-care (POC) systems to provide this test in global health settings. Acridine orange (AO) is an amphipathic, vital dye that intercalates leukocyte nucleic acids and acidic vesicles. It has been utilized by POC systems to identify the three main leukocyte subtypes: granulocytes, monocytes, and lymphocytes. Subtypes of leukocytes can be characterized using a fluorescence microscope, where the AO has a 450 nm excitation wavelength and has two peak emission …

The Biomechanics Of Music Performance, Rachel F. Bellisle, Jessika Decker

Senior Honors Projects

When first learning to play a wind instrument, beginner musicians are taught how to hold their instrument and correctly position their body. They are taught how to sit, where to put their hands and fingers on the keys, and how to hold their arms. This initial lesson on posture and hand positioning is often short, as one quickly moves on to learn the embouchure and breathing techniques that allow sound to be produced. As a musician progresses in skill, positioning is emphasized more, and they learn that it can affect their risk of strain or injury and improve their sound …

Sensitivity Of Diffuse Reflectance Spectroscopy To Dose- And Depth-Dependent Changes In Tumor Oxygenation After Radiation Therapy, Daria Semeniak

Graduate Theses and Dissertations

Along with chemotherapy, immunotherapy, and surgery, radiotherapy is one of the most common treatments used against cancer. Around 50% of all cancer patients undergo radiation therapy. While for some patients radiotherapy works efficiently and lead to a complete cancer disappearance, for others treatment outcome may be less favorable due to radioresistance processes happening within a tumor on the molecular level. Radioresistance remains a big challenge for modern oncology. The ability to identify radioresistance at the early stage of radiotherapy would help physicians to improve therapy efficiency. At the current moment, despite the rapid progress in cancer understanding and diagnostic modalities, …

Letter To The Members Of The Georgia Academy Of Science, David L. Bechler

Georgia Journal of Science

This letter is an update and review of recent activities in the Georgia Journal of Science. As of 2016, the journal has gone from a hardcopy format to a digital format through Digital Commons/Bepress (http://digitalcommons.gaacademy.org/gjs/). As a result of this, individuals worldwide now have access to journal articles free and online. Manuscripts accepted for publication are now placed online after the final acceptance and editing is complete.

A review on 20 March 2017 of online download events involving publications in 2016 shows that, of the 21 publications (the annual meeting program was included as one publication), there were …

Kinematics Of The Lower Extremities During Fundamental Martial Arts Tricking Techniques, Kevin P. Grassie

Honors Scholar Theses

Martial Arts Tricking (MAT) is a relatively new sport that combines martial arts, gymnastics, acrobatics, and breakdancing for the purposes of creating aesthetic and impressive combinations of kicks, flips and twists. It has been growing exponentially through social media and the overall athletic and entertainment communities. The sport is very unique in that the movements, with their blended influences, provide novel ways for athletes to generate and utilize their momentum in a creative way. The results often include off-axis flips and twists, single-leg landings, and complicated yet fluid techniques that easily chain together.

Due to the sport only being a …

Optimization Of Fluorescent Imaging In The Operating Room Through Pulsed Acquisition And Gating To Ambient Background Cycling, Kristian J. Sexton, Yan Zhao, Scott C. Davis, Shudong Jiang, Brian Pogue

Dartmouth Scholarship

The design of fluorescence imaging instruments for surgical guidance is rapidly evolving, and a key issue is to efficiently capture signals with high ambient room lighting. Here, we introduce a novel time-gated approach to fluorescence imaging synchronizing acquisition to the 120 Hz light of the room, with pulsed LED excitation and gated ICCD detection. It is shown that under bright ambient room light this technique allows for the detection of physiologically relevant nanomolar fluorophore concentrations, and in particular reduces the light fluctuations present from the room lights, making low concentration measurements more reliable. This is particularly relevant for the light …

Behavioral Sex Difference In Healthy Sprauge-Dawley Rats, Jeffrey Bagg, Jessica Obie, Fei Shang, Natalie Lista, Corinne Kiessling

Binghamton University Undergraduate Journal

Recently, the NIH has pushed for both sexes of a species to be incorporated into behavioral experiments. This push came as a result of an unchecked exclusion of females in experimentation. In rat studies, it is a common argument that females are more variable than males due to the presence of their estrous cycle. This study set out to evaluate this claim, and provide sex differences data for a variety of motor, anxiety, and cognitive behavioral tests. No sex differences in motor or anxiety behavior were found between the sexes. Males performed significantly better on the spontaneous alternation test of …

Social Workers’ Salaries Vs. Educational Student Debt Burden: A Losing Battle, Michael Wadham

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

College tuitions rise at disparate rates with starting salaries and inflation, causing student debt to weigh on social work graduates. Data was collected from 701 social workers in an NASW - Ohio Chapter survey to investigate this disparity and its consequences. The purpose of this study was to analyze the qualitative data set, 174 written comments, for themes and perceptions. The following themes, echoed in current research on the topics of social work salary and student debt burden, were identified: unmanageable debt and financial burden, varying lengths of time and repayment methods, social workers feeling undervalued and underpaid, loan forgiveness …

Legalization Of Gay Marriage And Its Impact On Military Stereotypes Of Homosexuals, Jasmine Moore

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Homosexuality has become a popular research topic in a variety of professional fields, and over the last decade has become a priority for the military. Since the implementation of the law repealing Don't Ask Don't Tell (DADT) researchers have questioned what effects repealing this law has had on the military as a whole. Particular attention has been spent on studying the attitudes and stereotypes about homosexuals after DADT was repealed. However, there is a lack of research examining how marriage equality affects society's stereotypes about homosexuals serving in the United States military.

It was hypothesized that participants that have personal …

Wright State University's Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts From Friday, April 21, 2017, Wright State University

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Annual Celebration of Research, Scholarship and Creative Activities on April 21, 2017.

Treating Chronic Post Herpetic Neuralgia Using Topical Superconcentrated Capsaicin, Jaree Naqvi, Scott Seider, Jason Miller, Cole Budinsky, Amol Soin

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Post Herpetic Neuralgia (PHN) is a painful condition that occurs after reactivation of the dormant Herpes Zoster Virus.Typically PHN presents with a unilateral rash affecting a single dermatome which is accompanied by burning, irritation, and hypersensitivity for >3 months.Current treatment includes anticonvulsants, tricyclic antidepressants, narcotic/nonnarcotic painkillers, and topical lidocaine.

We propose the utilization of a superconcentrated transdermal patch of capsaicin called Qutenza 8%, which is 300 times more potent than current OTC capsaicin. The treatment protocol using Qutenza to treat refractory PHN proposes a novel approach to the treatment of this condition.

Capsaicin is commonly known as the active chemical …

Khealth Bariatrics: A Multisensory Approach To Monitoring Patient’S Postsurgical Behavior, Revathy Venkataramanan, Utkarshani Jaimini, Amit Sheth, Joon K. Shim, Priti Parikh, Dene S. Berman

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The rate of obesity is on the rise reaching epidemic proportions. According to American Society for Metabolic and Bariatric Surgery (ASMBS), 500 million people all over the world are obese. The data from Centers for Disease Control and Prevention(CDC) shows that more than 36% of adults in the United States have obesity. According to World Health Organization (WHO), 65% of the world’s population lives in countries where the occurrence of death due to overweight and obesity is higher than being underweight. It is well established that weight loss surgery can play a significant role in reducing, or even eliminating medical …

Measuring Gender-Based Violence Attitude On Twitter, Goonmeet Bajaj, Tanvi Banerjee, Amir Hossein Yazdavar, Valerie L. Shalin, Amit Sheth

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

This study examines social media to analyze communication patterns, specifically in the Gender-Based Violence domain. It explores the pragmatic content of tweets to categorize them into one of the following groups: Belief, Fact Reporting, or Other to determine the tweeting practices prevalent in this domain.

2017 - The Twenty-Second Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Twenty-second Annual Symposium of Student Scholars, held on April 20, 2017. Includes abstracts from the presentations and posters.

Swosu Research And Scholarly Activity Fair 2017, Lisa Appeddu, Cj Smith

SWOSU Research and Scholarly Activity Fair Programs

Welcome to the Twenty-Fourth SWOSU Research and Scholarly Activity Fair! On display today are 158 poster presentations and 11 oral presentations, involving 314 student researchers, writers, presenters, and artists, and 47 faculty sponsors encompassing scholarly activity from the SWOSU Departments of Art, Communication, and Theatre; Biological Sciences; Business & Computer Science; Chemistry and Physics; Engineering Technology; Language & Literature; Music; Pharmaceutical Sciences; Psychology; and Social Sciences; and SWOSU School of Nursing and Allied Health Sciences. In addition, there are poster presentations from the Western Technology Center Biomedical Academy, Francis Tuttle Technology Center, El Reno Public Schools, and BlueSTEM AgriLearning …

Shear Driven Micro-Fluidic Pump For Cardiovascular Applications, Nihad E. Daidzic

Aviation Department Publications

A valveless shear-driven micro-fluidic pump design (SDMFP) for hemodynamic applications is presented in this work. One of the possible medical and biomedical applications is in-vivo hemodynamic (human blood circulation) support/assist. One or more SDMFPs can be inserted/implanted into vascular lumens in a form of a stent/duct in series and/or in parallel (bypass duct) to support blood circulation in-vivo. A comprehensive review of various micro-pump designs up to about mid 2000’s is given in [1,2]. Many of micropump designs considered are not suitable for in-vivo or even in-vitro medical/biomedical applications.

Operating principles, design, and SDMFP features are given in [3]. A …

General Aviation Hypoxia And Reporting Statistics, Timothy B. Holt, Jacqueline Luedtke, Claire Schindler

Publications

“All too often, pilots tell me they don't need physiological training because they don't fly that high. The statement points out the general feelings of a large majority of the aviation population. I suppose then the burning question is ‘why do we still have aircraft accidents?’” (Boshers, 2015). To this day there are no statistics on how often general aviation pilots experience hypoxia during everyday operations. General aviation pilots (i.e. non-commercial operations) were chosen for this study because:

• Little regulation regarding flight physiology training
• General attitude of invulnerability towards hypoxia
• No requirement to report hypoxia or similar events

Exploring Therapeutic Approaches For Marfan Syndrome Associated Aortic Aneurysm, Mitra Esfandiarei

Science Seminar Series

Esfandiearei will be discussing her research on understanding the underlying mechanisms contributing to the progression of aortic aneurysm in Marfan syndrome and the protective effects that exercise may have on the disease process in both laboratory animal models and human patients. Her research has been supported by the Canadian Institutes of Health Research (CIHR), Rare Diseases Foundation, and the Marfan Foundation.

Neuropeptide Modulation Of The Large Conductance Potassium (Bk) Channel In The Auditory System: Therapeutic Implications For Age-Related Hearing Loss, Ellliott James Brecht

USF Tampa Graduate Theses and Dissertations

The auditory temporal processing deficits associated with age-dependent hearing decline have been increasingly attributed to issues beyond peripheral hearing loss. Age-related hearing loss (ARHL), also known as presbycusis, is linked with changes in the expression of both excitatory and inhibitory neurotransmitters in the central auditory system. There are also age-related changes in the expression and function of the ion channels which mediate action potential firing. The slow, Ca²⁺ activated, K⁺ channels of the BK-type are essential in controlling both neurotransmitter release and neural communication via alteration of action potential durations, firing frequency, and neural adaptation. There are many …

Strategies For Reducing Preventable Hospital Readmissions On Medicare Patients, Andres Patricio Garcia-Arce

USF Tampa Graduate Theses and Dissertations

The high expenditure of healthcare in the United States (U.S.) does not translate into better quality of care. Indeed, the U.S. healthcare system is recognized by its lack of efficiency and waste (which represents about 20% of the country’s healthcare expenses). Lack of coordination is one of the most referenced causes of waste in the U.S. healthcare system, and preventable hospital readmissions have been acknowledged to be evidence of poor coordination of care. In fiscal year 2013, the Centers for Medicare and Medicaid Services (CMS) established financial penalties for inpatient care reimbursements in hospitals with excessive readmissions. All the same, …

Santa Clara Magazine, Volume 58 Number 1, Spring 2017, Santa Clara University

Santa Clara Magazine

24 - BIG WIN FOR A TINY HOUSE Turning heads and changing the housing game. By Matt Morgan.

28 - $100 MILLION GIFT TO BUILD John A. ’60 and Susan Sobrato make the largest gift in SCU history. Now see the Sobrato Campus for Discovery and Innovation that will take shape—and redefine the University. Illustration by Tavis Coburn.

36 - CUT & PASTE CONSERVATION We can alter wild species to save them. So should we? By Emma Marris. Illustrations by Jason Holley.

44 - INFO OFFICER IN CHIEF From his office overlooking the White House, Tony Scott J.D. ’92 set …

Water, Sanitation And Hygiene In Rwamwanja Refugee Settlement, Katelyn Bergl

Independent Study Project (ISP) Collection

No abstract provided.

Quality Of Water In Relation To Diarrheal Disease Incidence In Obunga, Tianna Herman

Independent Study Project (ISP) Collection

Kenyan cities are experiencing a serious dilemma in dealing with the large influx of people from rural parts of the country to the cities. Most people come to the city in pursuit of better opportunities and jobs. Rapid urban growth with little planning and preparation by the national and county governments has led to the development of informal settlements. These informal settlements are characterized by poor environmental conditions that predispose their residents for poor health conditions. Because of their illegal status, most residents of informal settlements in Kenya do not receive government services such as water, drainage, sewerage, and rubbish …

Research: South Dakota State University, Spring 2017, Christie Delfanian, Emily Weber

State of Discovery South Dakota State University's Research Magazine

Pharmacy researcher investigates how aspirin kills cancer cells [page] 1
Problem-solving, cornerstone of SDSU research [page] 2
Fluid flow model evaluates clotting risk in new stent graft design [page] 2
Sanford research project inspires graduate student [page] 3
Experience key to nurses' comfort in communicating with terminally ill patients [page] 4
Nondigestible starch feeds gut microbes, reduces inflammation [page] 5
Researchers investigate workings if antibody therapeutics [page] 6
DNA, RNA sequencing available in campus to researchers statewide [page] 7
QUBIC-R software helps researchers model, visualize gene expression networks [page] 8
Scientists assess survival of swine viruses in imported feed ingredients …

White Matter Hyperintensity Associations With Cerebral Blood Flow In Elderly Subjects Stratified By Cerebrovascular Risk, Ahmed A. Bahrani, David K. Powell, Guoqiang Yu, Eleanor S. Johnson, Gregory A. Jicha, Charles D. Smith

Biomedical Engineering Faculty Publications

Objective: This study aims to add clarity to the relationship between deep and periventricular brain white matter hyperintensities (WMHs), cerebral blood flow (CBF), and cerebrovascular risk in older persons. Methods: Deep white matter hyperintensity (dWMH) and periventricular white matter hyperintensity (pWMH) and regional gray matter (GM) and white matter (WM) blood flow from arterial spin labeling were quantified from magnetic resonance imaging scans of 26 cognitively normal elderly subjects stratified by cerebrovascular disease (CVD) risk. Fluidattenuated inversion recovery images were acquired using a high-resolution 3-dimensional (3-D) sequence that reduced partial volume effects seen with slicebased techniques. Results: dWMHs but not …

Speaker-Specific Adaptation Of Maeda Synthesis Parameters For Auditory Feedback, Joseph Vonderhaar

Master's Theses (2009 -)

The Real-time Articulatory Speech Synthesizer (RASS) is a research tool in the Marquette Speech and Swallowing lab that simultaneously collects acoustic and articulatory data from human participants. The system is used to study acoustic-to-articulatory inversion, articulatory-to-acoustic synthesis mapping, and the effects of real-time acoustic feedback. Electromagnetic Articulography (EMA) is utilized to collect position data via sensors placed in a subject’s mouth. These kinematic data are then converted into a set of synthesis parameters that controls an articulatory speech synthesizer, which in turn generates an acoustic waveform matching the associated kinematics. Independently from RASS, the synthesized acoustic waveform can be further …

Curated Exhibit Price Of War: Advances In Military Medicine, Laura J. Hall

Posters and Presentations

The Price of War: Advances in Military Medicine exhibit, curated by Laura J. Hall, MFA, explored the significant medical innovations arising from wartime, with a special focus on New Mexico's contributions. The exhibit highlighted the development of the atomic bomb at Los Alamos National Labs and the Trinity Site, the post-war work of the Atomic Bomb Casualty Commission, and the pioneering efforts of Dr. Randy Lovelace in space medicine. On display from April 1, 2017, to March 17, 2020, it documented key medical advancements, from field surgical installations in World War II to modern prosthetics and regenerative medicine, showing how …

Program And Proceedings: Nebraska Academy Of Sciences 1880–2017, 137th Anniversary Year, One Hundred-Twenty-Seventh Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

Program

Aeronautics and Space Science

Chemistry and Physics

Collegiate Academy: Biology

Collegiate Academy: Chemistry and Physics

Biological and Medical Sciences

Aeronautics and Space Science: Poster Session

Applied Science and Technology

Maiben Memorial Lecture

Anthropology

Earth Science

Applied Science and Technology

Teaching of Science and Mathematics

Environmental Sciences

Friend of Science Award: Kacie Baum and Todd Young

Chitosan Nanoparticle Modifications For Improved Gene Delivery In An Oral Dna Vaccine Application, Austin Helmink

Honors Program: Senior Projects (Public)

Vaccines represent one of the most significant medical innovations of the 20^th century, resulting in the eradication or near eradication of a handful of deadly diseases. However, many infectious diseases remain resistant to effective vaccination, largely due to a lack full immune activation by traditional protein-based vaccines. A promising alternative vaccination strategy is the emerging development of DNA vaccines, which rely upon the delivery of exogenous genetic material to host cells encoding for a viral or bacterial antigen in order to induce a robust immune response by closely mimicking live infection. The delivery of genetic material requires a carrier …

Undergraduate Research On General Aviation Hypoxia: A Student’S Perspective, Claire Schindler

Discovery Day - Prescott

During the fall academic term of 2016, an opportunity arose through the College of Aviation to serve as an undergraduate research assistant. Through discussion with faculty mentors, it was decided that a severely overlooked aspect of the aviation industry was survivors of hypoxia, especially in the less regulated general aviation community. The problem this study addresses is the uncertainty of the common circumstances that general aviation pilots find themselves in that create a hypoxic state, as well as whether or not that pilot reported the occurrence to the proper establishments. The results of this study showed not only those that …