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Full-Text Articles in Engineering

Development Of Fully Balanced Ssfp And Computer Vision Applications For Mri-Assisted Radiosurgery (Mars), Jeremiah Sanders May 2020

Development Of Fully Balanced Ssfp And Computer Vision Applications For Mri-Assisted Radiosurgery (Mars), Jeremiah Sanders

Dissertations and Theses (Open Access)

Prostate cancer is the second most common cancer in men and the second-leading cause of cancer death in men. Brachytherapy is a highly effective treatment option for prostate cancer, and is the most cost-effective initial treatment among all other therapeutic options for low to intermediate risk patients of prostate cancer. In low-dose-rate (LDR) brachytherapy, verifying the location of the radioactive seeds within the prostate and in relation to critical normal structures after seed implantation is essential to ensuring positive treatment outcomes.

One current gap in knowledge is how to simultaneously image the prostate, surrounding anatomy, and radioactive seeds within the …


Peptoid And Antibody-Based Gfp Sensors, Solomon Isu May 2020

Peptoid And Antibody-Based Gfp Sensors, Solomon Isu

Graduate Theses and Dissertations

In this work, we have made and characterized a pair of immunobiosensors for detecting the green fluorescent protein (GFP) in an aqueous matrix. An anti-GFP antibody-based biosensor was assembled to detect GFP, while a novel peptoid (N-substituted oligomers of glycine designated as IOS-1) biosensor was also assembled for GFP detection. A quartz crystal microbalance (QCM) gold sensor was used as the supporting substrate for self-assembly of the immunobiosensors. Gravimetric measurements of the QCM gold sensor during immunobiosensor construction and operation were available in real-time using a QCM instrument. X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, and Fluorescence microscopy were used …


Artifact Identification For Blood Pressure And Photoplethysmography Signals In An Unsupervised Environment, Pooi Khoon Lim May 2020

Artifact Identification For Blood Pressure And Photoplethysmography Signals In An Unsupervised Environment, Pooi Khoon Lim

Student Works (2020-2029)

Physiological signals play a significant role in clinical diagnosis, it always acts as a major input of a decision support system. However, the physiological signal is easily corrupted by different factors especially motion artifacts. Several research works have been tried to recover the underlying physiological signal by suppressing the artifact. However, not much attention has been paid to situation where the artifact is too extreme and the artifact suppression is not possible. In this situation, physiological signal quality must be evaluated before any further assessment. In this study, an automated artifact detection algorithm was developed for Blood Pressure and PPG …


Designing An Antibiotic Eluting Trauma Screw To Reduce Short Term Infection In Bone Fractures, Dominic Lincoln Apr 2020

Designing An Antibiotic Eluting Trauma Screw To Reduce Short Term Infection In Bone Fractures, Dominic Lincoln

Honors Theses

Orthopedic infection in the United States is one of the most common and severe health risks faced by trauma patients. The most prevalent infection is orthopedic and trauma device-related infection (ORDI) and often occurs in long bones at the fracture site. The purpose of this paper is to explore this infection, its causes, and solutions currently on the market while providing novel solutions to the problem. The designs proposed will be evaluated for their effectiveness and value, while attempting to keep costs low for all stakeholders. The feasibility of patenting these ideas will also be considered, as will the testing …


Développement D’Outils Pour L’Évaluation Du Processus D’Implantation Et L’Analyse Économique D’Une Intervention Ergonomique : Le Cas D’Une Intervention De Prévention Des Troubles Musculosquelettiques Dans L’Industrie De L’Abattage Et De La Transformation De La Volaille, Émilie Desjardins, Hélène Sultan-Taïeb, France St-Hilaire, Nicole Vézina, Élise Ledoux, Patricia Bélanger, Rita Naji Apr 2020

Développement D’Outils Pour L’Évaluation Du Processus D’Implantation Et L’Analyse Économique D’Une Intervention Ergonomique : Le Cas D’Une Intervention De Prévention Des Troubles Musculosquelettiques Dans L’Industrie De L’Abattage Et De La Transformation De La Volaille, Émilie Desjardins, Hélène Sultan-Taïeb, France St-Hilaire, Nicole Vézina, Élise Ledoux, Patricia Bélanger, Rita Naji

Rapports de recherche scientifique

Depuis les années 1990, Nicole Vézina et son équipe ont réalisé des travaux de recherche qui ciblent l’apprentissage de l’affilage et de l’aiguisage des couteaux dans un objectif de prévention des troubles musculosquelettiques (TMS). Le cas à l’étude est une intervention implantée dans le département d’éviscération d’une usine d’abattage et de transformation de la volaille située au Québec. Il s’agit d’une intervention ergonomique de prévention des TMS avec plusieurs types de transfert d’apprentissage dans un contexte de travail à la chaîne à cadence élevée. L’objectif général de cette étude était de développer des outils de collecte de données adaptés aux …


Faculty Instruction Face Shield Project, David Holden, John Schneiderhan Apr 2020

Faculty Instruction Face Shield Project, David Holden, John Schneiderhan

Michigan Tech 3D Designs

Early in the spring of 2020 project contributors David Holden and John Schneiderhan began test printing a variety of open source Personal Protective Equipment (PPE)/Covid related items that could help protect or prevent the spread of the emerging virus. With assistance from Pete Baril of the Western Upper Peninsula Health Department (WUPHD) approval was obtained for the face shields to be used in the health care and nursing homes in the area. With the support and approval from university and library administration efforts were coordinated with Dr. Joshua Pearce and the students from the MOST lab to concentrate on the …


Stationary Exercise Classification Using Imus And Deep Learning, Andrew M. Heroy, Zackary Gill, Samantha Sprague, David Stroud, John Santerre Apr 2020

Stationary Exercise Classification Using Imus And Deep Learning, Andrew M. Heroy, Zackary Gill, Samantha Sprague, David Stroud, John Santerre

SMU Data Science Review

In the current market, successful fitness tracking devices utilize heart rate and GPS to determine performance. These devices are useful, but don't extensively classify stationary exercise. This paper proposes a modern approach for tuning and investigating optimal neural network types on stationary exercises using Inertial Measurement Units (IMUs). Using three IMUs located on the ankle, waist, and wrist, data is collected to map the body as it moves during the stationary physical activity. A novel five-stage deep learning tuning system was written and deployed to classify user movement as one of three classes: air squats, jumping jacks, and kettlebell swings. …


2020 - The Twenty-Fourth Annual Symposium Of Student Scholars Apr 2020

2020 - The Twenty-Fourth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Twenty-fourth Annual Symposium of Student Scholars, held on April 16, 2020. Includes abstracts from the presentations and posters.


Current Status Of Magnetic Resonance On Saliva For Oral And Dental Health Early Diagnosis, Anastasia Katsavochristou, Dimitrios Koumoulis Apr 2020

Current Status Of Magnetic Resonance On Saliva For Oral And Dental Health Early Diagnosis, Anastasia Katsavochristou, Dimitrios Koumoulis

Oral Health Practice Faculty Publications

Magnetic resonance spectroscopy of biomolecules has recently gained attention for clinical diagnosis. Its combination with saliva collection and analysis can promote early disease detection and monitoring, by identifying biomarkers of specific underlying pathology or disease as detected in saliva. With this novel, non-invasive technique, certain salivary biomarkers have been linked to dental and periodontal tissues pathology, as well as to specific head and neck cancer malignancies. At present, diagnostic biomarkers are still in need for further identification (e.g., diagnosis and monitoring of Sjögren’s syndrome), and nuclear magnetic resonance spectroscopy has been found to be a promising technique to compliment the …


Biomimetic Gold Nanoshell-Loaded Macrophage For Photothermal Biomedicine, Sung Hun Kang, Yong Kyu Lee, Il Seok Park, In-Kyu Park, Seok Min Hong, Soon Young Kwon, Young Hee Choi, Steen J. Madsen, Henry Hirschberg, Seok Jin Hong Apr 2020

Biomimetic Gold Nanoshell-Loaded Macrophage For Photothermal Biomedicine, Sung Hun Kang, Yong Kyu Lee, Il Seok Park, In-Kyu Park, Seok Min Hong, Soon Young Kwon, Young Hee Choi, Steen J. Madsen, Henry Hirschberg, Seok Jin Hong

Integrated Health Sciences Faculty Research

The purpose of this study was to investigate the effect of photothermal treatment (PTT) with gold nanoshell (ANS) using a macrophage-mediated delivery system in a head and neck squamous cell carcinoma (HNSCC) cell line. To achieve this, ANS-loaded rat macrophages (ANS-MAs) were prepared via the coculture method with ANS. The human HNSCC (FaDu cell) and macrophage (rat macrophage; NR8383 cell) hybrid spheroid models were generated by the centrifugation method to determine the possibility of using ANS-MAs as a cancer therapy. These ANS-MAs were set into the tumor and macrophage hybrid spheroid model to measure PTT efficacy. Kinetic analysis of the …


Walking Kinematics In Young Children With Limb Loss Using Early Versus Traditional Prosthetic Knee Prescription Protocols, Mark Daniel Geil, Zahra Safaeepour, Brian Giavedoni, Colleen Coulter Apr 2020

Walking Kinematics In Young Children With Limb Loss Using Early Versus Traditional Prosthetic Knee Prescription Protocols, Mark Daniel Geil, Zahra Safaeepour, Brian Giavedoni, Colleen Coulter

Faculty Articles

The traditional treatment protocol for young children with congenital or acquired amputations at or proximal to the knee prescribes a prosthesis without a working knee joint, based in part on the assumption that a child learning to walk cannot properly utilize a passively flexing prosthetic knee component. An alternative to this Traditional Knee (TK) protocol is an “Early Knee” (EK) protocol, which prescribes an articulating prosthetic knee in the child’s first prosthesis, during development of crawling and transitioning into and out of upright positions. To date, no study has compared samples of children with limb loss at or proximal to …


The Natural Historian’S Guide To The Ct Galaxy: Step-By-Step Instructions For Preparing And Analyzing Computed Tomographic (Ct) Data Using Cross-Platform, Open Access Software, T. J. Buser, O. F. Boyd, A. Cortés, Cassandra M. Donatelli, M. A. Kolmann, J. L. Luparell, J. A. Pfeiffenberger, B. L. Sidlauskas, A. P. Summers Apr 2020

The Natural Historian’S Guide To The Ct Galaxy: Step-By-Step Instructions For Preparing And Analyzing Computed Tomographic (Ct) Data Using Cross-Platform, Open Access Software, T. J. Buser, O. F. Boyd, A. Cortés, Cassandra M. Donatelli, M. A. Kolmann, J. L. Luparell, J. A. Pfeiffenberger, B. L. Sidlauskas, A. P. Summers

Engineering Faculty Articles and Research

The decreasing cost of acquiring computed tomographic (CT) data has fueled a global effort to digitize the anatomy of museum specimens. This effort has produced a wealth of open access digital three-dimensional (3D) models of anatomy available to anyone with access to the Internet. The potential applications of these data are broad, ranging from 3D printing for purely educational purposes to the development of highly advanced biomechanical models of anatomical structures. However, while virtually anyone can access these digital data, relatively few have the training to easily derive a desirable product (e.g., a 3D visualization of an anatomical structure) from …


Cardiovascular Surgery Practice Remodel: Increasing Job Satisfaction And Reducing Turnover Rates Of Advanced Practice Providers, Christian Brooks Apr 2020

Cardiovascular Surgery Practice Remodel: Increasing Job Satisfaction And Reducing Turnover Rates Of Advanced Practice Providers, Christian Brooks

Doctor of Nursing Practice Scholarly Project

Cardiovascular Surgery Practice Remodel: Increasing Job Satisfaction and Reducing Turnover Rates of Advanced Practice Providers

Background: The CVS practice in a Midwestern state had a shift in morale and job satisfaction in their advanced practice providers (APPs). This shift lead to the high turnover rate of 35% in 2018. In an effort to bring a halt to the high turnover rate, and to continue the excellent patient care for which the hospital is known, hospital administration became involved and set up a committee to guide the development of a new CVS APP practice model. The goal was to develop …


Hybrid Electro-Plasmonic Stimulation Of Primary Neurons, Ratka Damnjanovic Apr 2020

Hybrid Electro-Plasmonic Stimulation Of Primary Neurons, Ratka Damnjanovic

USF Tampa Graduate Theses and Dissertations

Biomedical prosthetics utilizing electrical stimulation have limited, effective spatial resolution due to spread of electrical currents to surrounding tissue, causing nonselective stimulation. So, precise spatial resolution is not possible for traditional neural prosthetic devices, such as cochlear implants. More recently, alternative methods utilize optical stimulation, mainly infrared, sometimes paired with nanotechnology for stimulating action potentials, which has its own drawbacks, as it may heat surrounding tissue. Recently, we employed plasmonic stimulation methods utilizing gold nanoparticle-coated nanoelectrodes to convert visible light pulses into localized surface plasmon resonance transduction for stimulation of electrically excitable cells, which had limited success. Here, we report …


Medication Errors Within The Clinical Setting: A Quality Improvement Project, Gracie Smith, Mary Thornburg, Connor Noble, Breanna Markwell, Sarah Rigsby, Suzi White Apr 2020

Medication Errors Within The Clinical Setting: A Quality Improvement Project, Gracie Smith, Mary Thornburg, Connor Noble, Breanna Markwell, Sarah Rigsby, Suzi White

2022 Celebration of Student Scholarship - Poster Presentations

During a clinical rotation at a large urban teaching hospital, the occurrence of medication errors noted resulted in negative impacts on patient wellness. Research studies indicate that the U.S. spends more than $40 billion each year as a result of medication errors. A large portion of these medication errors are preventable. A thorough literature review of 40 research studies was conducted to identify issues associated with medication errors. This quality improvement project aims to identify the prevalence of medication errors, their effect on patient wellness, its monetary effects in healthcare, and what preventative interventions can be implemented to prevent such …


Craft Academy Solar Powered Racing (Caspr) Team, Andrew Dorn, Ally Hall, Bryce Watkins, Hayley Milner, Kaleb Trent, Owen Day, Sawyer Putnam, Joyce Stubbs, Steve Stubbs Apr 2020

Craft Academy Solar Powered Racing (Caspr) Team, Andrew Dorn, Ally Hall, Bryce Watkins, Hayley Milner, Kaleb Trent, Owen Day, Sawyer Putnam, Joyce Stubbs, Steve Stubbs

2022 Celebration of Student Scholarship - Poster Presentations

The ultimate goal of the CASPR team is to build a solar powered car to race in the solar car for the Solar Car Challenge Classic Division, and race in a cross-county race or at the famous Texas Motor Speedway. The car must have taillights, blinkers, headlights, and extra suspension. For the fall semester of 2021, we researched different parts and other solar cars to see what would be the best fit most beneficial. We were able to find all the parts needed for the construction of the car. The Solar Car Challenge website provides some resources to make finding …


Team Creation Methods In Practice: Understanding The Potential Effects Of Nonverbal Communication In The Leadership Of Team Formation, Troy Allen Robertson Apr 2020

Team Creation Methods In Practice: Understanding The Potential Effects Of Nonverbal Communication In The Leadership Of Team Formation, Troy Allen Robertson

Dissertations

Teams require leadership, even if they are self-managed. The group of individuals who make up a team must be gathered in some form or another. For self managed teams to function successfully, the first step is the process of creating the team. Many aspects may factor into the creation process. Often time is of the essence and methods to quickly assess and form teams show merit. First impressions in general are based largely on nonverbal communication. The focus of this mixed-methods concurrent embedded study is to analyze the potential effects of nonverbal communication on influencing team creation. A group of …


Santa Clara Magazine, Volume 61 Number 2, Spring 2020 [Print Issue V.61:1], Santa Clara University Apr 2020

Santa Clara Magazine, Volume 61 Number 2, Spring 2020 [Print Issue V.61:1], Santa Clara University

Santa Clara Magazine

14 - THE UPSTART How Michael Mondavi ’66 helped get Napa on the wine map. By Ron Hansen.

18 - OF WOMEN AND MEN Emeritus professors dish on their research into wine and women. By Tracy Seipel.

22 - A SIGN OF LIGHT A Jesuit priest finds meaning on death row. By George Williams, S.J.

26 - FIRE AND WINE As the climate changes, what’s next for wine remains murky. By Tracy Seipel.


Computational Approach To Correcting Joint Instability In Patients With Recurrent Patellar Dislocation, Oliver Alvarez, Robert N. Steensen, Paul J. Rullkoetter, Clare K. Fitzpatrick Apr 2020

Computational Approach To Correcting Joint Instability In Patients With Recurrent Patellar Dislocation, Oliver Alvarez, Robert N. Steensen, Paul J. Rullkoetter, Clare K. Fitzpatrick

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Patellar dislocation is a debilitating injury common in active adolescents and young adults. Conservative treatment after initial dislocation is often recommended, but almost half of these patients continue to suffer from recurrent dislocation. The objective of this study was to compare preoperative patellofemoral joint stability with stability after a series of simulated procedures, including restorative surgery to correct to pre-injury state, generic tibial tubercle osteotomy, patient-specific reconstructive surgery to correct anatomic abnormality, less invasive patient-specific surgery, and equivalent healthy controls. Three-dimensional, subject-specific finite element models of the patellofemoral joint were developed for 28 patients with recurrent patellar dislocation. A …


Spring 2020, Joëlle Walls Apr 2020

Spring 2020, Joëlle Walls

The Investigator Research Magazine

Dear readers,

We are proud to present the spring issue of The Investigator, giving you an inside look into the varied research and scholarly activities taking place at Kennesaw State.

In a new interview, President Pamela Whitten discusses KSU's growing research reputation and lessons learned from her own experiences as a researcher and mentor. Similarly, our cover story follows three First-Year Scholars as they explore the possibilities of research in Martin Hudson's lab through a new Office of Undergraduate Research initiative.

This publication would not have been possible without the contributions of the editorial team, including undergraduates Kaelyn Ireland, Geena …


How Do Surgeon Preferences And Technique Variances Affect Outcome?, Anastasia Axiopoulou, Caroline G. L. Cao, Katherine Lin Md, Keith Watson Md Apr 2020

How Do Surgeon Preferences And Technique Variances Affect Outcome?, Anastasia Axiopoulou, Caroline G. L. Cao, Katherine Lin Md, Keith Watson Md

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The goal of the research project is to create a blue-print of a robot-assisted hysterectomy procedure to support design and evaluation of technology to enhance system performance. To create this blue-print, we will conduct a task analysis, model the cognitive task flow and decision making, and develop a simulation of the hysterectomy procedure. The surgical simulation will be used as a platform to train surgeons on robotic-assisted hysterectomies, as well as to assess learning and performance. Additionally, it will be used to design and develop techniques and novel technology to support surgeons in their performance of the surgery. Current research …


Identifying Easy Indicators Of Dementia, Swati Padhee, Tanvi Banerjee, Valerie L. Shalin, Krishnaprasad Thirunarayan Apr 2020

Identifying Easy Indicators Of Dementia, Swati Padhee, Tanvi Banerjee, Valerie L. Shalin, Krishnaprasad Thirunarayan

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Alzheimer’s Disease (AD) is a degenerative chronic neurodegenerative disease that affects millions of people and whose care costs billions of dollars. There is growing evidence that variations in speech and language may be early indicators of dementia. One of the most initial symptoms of dementia is speech impairment, including difficulty in finding words and changes to the grammatical structure. These early indicators can be detected by having the patients perform a picture description task, such as the Cookie Theft task from the Boston Diagnostic Aphasia Examination. However, much of the state-of-the-art NLP for dementia has been limited due to the …


Measuring Nomophobia And Exploration Of Consequences And Comorbidities, Sarah Marie Fryman, William L. Romine Apr 2020

Measuring Nomophobia And Exploration Of Consequences And Comorbidities, Sarah Marie Fryman, William L. Romine

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Excessive use of smartphones has coined the term “Nomophobia”, or fear of not being able to use your smartphone. For many, these devices have become an extension of ourselves, which raises hesitation on whether or not society has become addicted to smartphones. Specific diagnostic criteria for smartphone addiction have yet to be settled, and even appropriate to use the word “addiction” when describing excessive usage of smartphones is controversial.

We therefore explore utilize current measures to explore the symptoms of nomophobia and their hierarchy, as well as comorbidities including social anxiety, self-esteem, distracted driving and sleep quality. A total of …


Predicting Alcohol Withdrawal In Intensive Care Units, Reza Sadeghi, Tanvi Banerjee, William L. Romine Apr 2020

Predicting Alcohol Withdrawal In Intensive Care Units, Reza Sadeghi, Tanvi Banerjee, William L. Romine

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

Alcohol use disorder is a common health issue in older adults who are facing depression caused by retirement, loss of a spouse, pain, and sleep problems. The prolonged, heavy alcohol ingestion will lead to high alcohol dependency such that cessation or reduction of using alcohol causes alcohol withdrawal syndrome (AWS) in roughly 4 to 72 hours after the last drink. During the initial 8 hours, patients face anxiety, insomnia, nausea, and abdominal pain. This condition is followed by high blood pressure, increased body temperature, unusual heart rate, and confusion. If this syndrome does not receive any treatment, the patients will …


Program And Proceedings: Nebraska Academy Of Sciences 1880–2020, 140th Anniversary Year, One Hundred-Thirtieth Annual Meeting Apr 2020

Program And Proceedings: Nebraska Academy Of Sciences 1880–2020, 140th Anniversary Year, One Hundred-Thirtieth Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

No abstract provided.


Supporting Self-Regulation Of Children With Adhd Using Wearables: Tensions And Design Challenges, Franceli L. Cibrian, Kimberley D. Lakes, Arya Tavakoulnia, Kayla Guzman, Sabrina Schuck, Gillian R. Hayes Apr 2020

Supporting Self-Regulation Of Children With Adhd Using Wearables: Tensions And Design Challenges, Franceli L. Cibrian, Kimberley D. Lakes, Arya Tavakoulnia, Kayla Guzman, Sabrina Schuck, Gillian R. Hayes

Engineering Faculty Articles and Research

The design of wearable applications supporting children with Attention Deficit Hyperactivity Disorders (ADHD) requires a deep understanding not only of what is possible from a clinical standpoint but also how the children might understand and orient towards wearable technologies, such as a smartwatch. Through a series of participatory design workshops with children with ADHD and their caregivers, we identified tensions and challenges in designing wearable applications supporting the self-regulation of children with ADHD. In this paper, we describe the specific challenges of smartwatches for this population, the balance between self-regulation and co-regulation, and tensions when receiving notifications on a smartwatch …


El Artista Está En Línea: E-Performance En El Tiempo De Covid-19, Ezequiel N. González Apr 2020

El Artista Está En Línea: E-Performance En El Tiempo De Covid-19, Ezequiel N. González

Independent Study Project (ISP) Collection

Esta investigación propone una lectura detallada y comparativa de varias e-performances creadas por el artista visual uruguayo Ernesto Rizzo y la performer argentina Susy Shock, trazando un corpus de trabajo creado durante la crisis de COVID-19 y compartido en Instagram desde finales de marzo a finales de mayo de 2020. Al centrarse en el giro digital del arte de performance debido a las particularidades de la cuarentena, esta investigación busca distinguir este momento de "e-performance", entendiendo cuáles serán sus ramificaciones para el/la artista y el arte de performance en general. Así, a través de una reflexión teórica sobre el terreno …


The Geographic Disparities In Transportation-Related Physical Activity In The United States: An Analysis Of The 2017 Nhts Data, Hongwei Dong Apr 2020

The Geographic Disparities In Transportation-Related Physical Activity In The United States: An Analysis Of The 2017 Nhts Data, Hongwei Dong

Mineta Transportation Institute

Research on the relationship between urbanicity and physical activity yielded mixed results despite many studies consistently showing that residents tended to undertake more transportation-related physical activity in a more urban environment. This study analyzed the 2017 NHTS data to examine the geographic disparities in physical activity, particularly transportation-related physical activity in the United States. Our analysis suggests the relationship between urbanicity and physical activity demonstrates a flat U-shape in graphed data. Residents are more physically active when they live in the areas from the two ends of the urbanization spectrum: inner cities and inner suburbs of large metropolitan areas and …


Impedance Analysis Of Tissues In Nspef Treatment For Cancer Therapy, Edwin Ayobami Oshin Apr 2020

Impedance Analysis Of Tissues In Nspef Treatment For Cancer Therapy, Edwin Ayobami Oshin

Biomedical Engineering Theses & Dissertations

Nanosecond pulsed electric field (nsPEF) for cancer therapy is characterized by applications of high voltage pulses with low pulsed energy to induce non-thermal effects on tissues such as tumor ablation. It nonthermally treats tissues via electroporation. Electroporation is the increase in permeabilization of a cell membrane due to the application of high pulsed electric field. The objective of this study was to investigate the effect of nsPEF on tissue by monitoring the tissue’s impedance in real-time. Potato slices (both untreated and electroporated), and tumors extracted from female BALBc mice were studied. 100ns, 1-10kV pulses were applied to the tissues using …


Supercavitation Capabilities On A Submarine, Adam Vu Mar 2020

Supercavitation Capabilities On A Submarine, Adam Vu

Georgia College Student Research Events

Submarines have shaped the way wars have been fought and have been influential in our understanding of fluid dynamics. In the past, supercavitation has been implemented to an idea that has been used to significantly increase the velocity of torpedoes in Chinese and Russian submarines. An example of this is the Russian VA-111 Shkval torpedo. The idea being that if your torpedo is expelling a gas out of the nose cone region, creating a boundary layer between the water and the torpedo, the torpedo will be facing much less resistance relative to when it was traveling in water alone. This …