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Articles 3181 - 3210 of 30047
Full-Text Articles in Engineering
Droplet Jump From A Particle Bed, Karl Cardin, Facundo Cabrera-Booman, Raúl Bayoán Cal
Droplet Jump From A Particle Bed, Karl Cardin, Facundo Cabrera-Booman, Raúl Bayoán Cal
Mechanical and Materials Engineering Faculty Publications and Presentations
Drop tower experiments have been performed to study droplet jump from a particle bed across a wide range of fluid viscosities. Here the droplet jumps from the particle bed in response to the apparent step reduction from terrestrial gravity to microgravity when the experiment is dropped and enters free fall. The presence of a particle layer has been found to affect contact line dissipation and the overall jumping behavior of droplets. Additionally, the study has identified the impact of the Ohnesorge number (Oh) on droplet morphology. The investigation has yielded results that not only validate a modified version of the …
Fibrous Finite Element Modeling Of The Optic Nerve Head Region, Mohammad R. Islam, Fengting Ji, Manik Bansal, Yi Hua, Ian A. Sigal
Fibrous Finite Element Modeling Of The Optic Nerve Head Region, Mohammad R. Islam, Fengting Ji, Manik Bansal, Yi Hua, Ian A. Sigal
Mechanical Engineering Faculty Publications
The optic nerve head (ONH) region at the posterior pole of the eye is supported by a fibrous structure of collagen fiber bundles. Discerning how the fibrous structure determines the region biomechanics is crucial to understand normal physiology, and the roles of biomechanics on vision loss. The fiber bundles within the ONH structure exhibit complex three-dimensional (3D) organization and continuity across the various tissue components. Computational models of the ONH, however, usually represent collagen fibers in a homogenized fashion without accounting for their continuity across tissues, fibers interacting with each other and other fiber-specific effects in a fibrous structure. We …
Computational Modelling Of A Triaxial Vibrating Sample Magnetometer, Leo Rodriguez, Arjun Sapkota, Jonathan Alvarado, Jitendra S. Tate, Wilhelmus J. Geerts
Computational Modelling Of A Triaxial Vibrating Sample Magnetometer, Leo Rodriguez, Arjun Sapkota, Jonathan Alvarado, Jitendra S. Tate, Wilhelmus J. Geerts
Mechanical Engineering Faculty Publications
Magnetic Field Assisted Additive Manufacturing (MFAAM) enables 3D printing of magnetic materials of various shapes which exhibit a complex anisotropy energy surface containing contributions generated from different origins such as sample, particle, and agglomerate shape anisotropy, flow and field induced anisotropy, and particle crystal anisotropy. These novel magnet shapes require the need to measure the x, y, and z components of the magnetic dipole moment simultaneously to fully understand the magnetic reversal mechanism and unravel the complex magnetic anisotropy energy surface of 3D printed magnetic composites. This work aims to develop a triaxial vibrating sample magnetometer (VSM) by adding a …
Analysis Of Wind Turbine Wake Dynamics By A Gaussian-Core Vortex Lattice Technique, Apurva Baruah, Fernando L. Ponta
Analysis Of Wind Turbine Wake Dynamics By A Gaussian-Core Vortex Lattice Technique, Apurva Baruah, Fernando L. Ponta
Michigan Tech Publications
The development and deployment of the next generation of wind energy systems calls for simulation tools that model the entire wind farm while balancing accuracy and computational cost. A full-system wind farm simulation must consider the atmospheric inflow, the wakes and consequent response of the multiple turbines, and the implementation of the appropriate farm-collective control strategies that optimize the entire wind farm’s output. In this article, we present a novel vortex lattice model that enables the effective representation of the complex vortex wake dynamics of the turbines in a farm subject to transient inflow conditions. This work extends the capabilities …
Improving The Energy Efficiency Of Residential Buildings In Egypt Through Whole Building Simulations, Habiba Aly
Improving The Energy Efficiency Of Residential Buildings In Egypt Through Whole Building Simulations, Habiba Aly
Theses and Dissertations
Residential buildings consume around 40% of total electricity consumption in Egypt. This research investigates the energy saving potential of the Green Pyramid Rating system (GPRS) and Tarsheed rating system on the building envelopes of mid-rise middle income residential buildings in Cairo through energy modelling and simulation. The study evaluates the economic feasibility of the recommendations of the two rating systems through Life Cycle Cost (LCC), Simple Payback Period (SPP), Discounted Payback Period (DPP), Net Present Value (NPV), and Internal Rate of Return (IRR) Calculations. This research also aims to develop energy efficiency recommendations to achieve 30% energy savings above the …
A 3d Imaging-Based Critique Of Wire Arc Additive Manufacturing (Waam) Simulations, Omar Oraby
A 3d Imaging-Based Critique Of Wire Arc Additive Manufacturing (Waam) Simulations, Omar Oraby
Theses and Dissertations
Residual stresses play a critical role in the mechanical behavior and structural integrity of engineered components. Understanding and quantifying these stresses are essential for ensuring the reliable performance and durability of materials and structures. Traditionally destructive methods are used that involve sample sectioning and material removal. However, non-destructive methods have gained popularity due to their advantages in preserving the specimen's integrity for further testing and material waste reduction. Among these techniques, Digital Image Correlation (DIC) stands out as a powerful non-contact and full-field measurement approach. DIC captures displacements and strain distributions by analyzing the deformation of speckle patterns on the …
Development Of An Electromagnetic System For Wireless Magnetic Manipulation Of Soft Capsule Endoscope For Drug Delivery Applications, Nada Ashraf Hussein Mahmoud
Development Of An Electromagnetic System For Wireless Magnetic Manipulation Of Soft Capsule Endoscope For Drug Delivery Applications, Nada Ashraf Hussein Mahmoud
Theses and Dissertations
Wireless capsule endoscopy (WCE) is a remarkable diagnostic device that examines the gastrointestinal (GI) tract. The WCE is a small capsule integrated with a camera that is used to visualize the inner mucosa of the GI tract. WCE has been proven to be the most effective method to diagnose GI diseases and GI cancers. The procedure reduces the discomfort and risk compared to conventional endoscopy methods. However, current WCEs lack the ability to take a biopsy or deliver a drug to a specific location. Those therapeutic functions can be introduced by wirelessly controlled WCEs. This thesis introduces an electromagnetic system …
Cardiac Active Tension Modeling Via Genetic Algorithm-Optimized Fractional Order Systems, Afnan Khaled Elhamshari
Cardiac Active Tension Modeling Via Genetic Algorithm-Optimized Fractional Order Systems, Afnan Khaled Elhamshari
Theses and Dissertations
Developing a computational model to model cardiac activity has been increasingly important in recent decades. Accurate cell-level active tension modeling for cardiomyocytes is critical to understanding cardiac functionality on a patient-specific basis and developing an effective in-silico cardiac model. However, cell-level models in the literature fail to account for viscoelasticity and inter-patient variations in active tension. This research proposes a genetic algorithm-optimized, fractional order system to model cell-level active tension by extending Land’s state-of-the-art model of cardiac contraction. The model features the (left) Caputo derivative of six state variables that identify the mechanistic origins of viscoelasticity in a myocardial cell …
Study Of Vortices Formation In Lateral Intakes Of Pumping Stations, Muhammad Elgindi
Study Of Vortices Formation In Lateral Intakes Of Pumping Stations, Muhammad Elgindi
Theses and Dissertations
The inefficient design of pumping stations leads to undesirable flow characteristics and the formation of vortices in the sump. These undesirable flow features adversely affect the pumping unit performance and increase the operation and maintenance cost. The aim of this thesis is to assess the ability of the Realizable turbulence model to predict the formation of free-surface and submerged vortices within lateral pumping stations’ intakes. Additionally, the study aims to investigate the effect of the flow ratio and bottom clearance on the flow characteristics and the vortices formation in the sump. Finally, the study introduces an assessment of curtain walls …
Experimental Investigation On Flexural Behavior And Energy Absorption Of Lightweight Sandwich Panels With Aluminum Honeycomb Core Embedded By Thin-Ply Carbon-Glass Fibers/Epoxy Face Sheets, Reyhanehsadat Kazemian, Nader Fanaie, S. M. Saleh Mousavi-Bafrouyi, Juhyeong Lee
Experimental Investigation On Flexural Behavior And Energy Absorption Of Lightweight Sandwich Panels With Aluminum Honeycomb Core Embedded By Thin-Ply Carbon-Glass Fibers/Epoxy Face Sheets, Reyhanehsadat Kazemian, Nader Fanaie, S. M. Saleh Mousavi-Bafrouyi, Juhyeong Lee
Mechanical and Aerospace Engineering Faculty Publications
Generally, designing lightweight and thin-walled structures with high mechanical performance is one of the challenging issues for mechanical and civil engineering sciences. To this aim, sandwich panels which have been designed and analyzed in present research include aluminum honeycomb core (H) and UD-thin-ply carbon (C)/glass fiber fabric (G) composite facings and investigated the effect of hybridization and stacking sequence on their static and dynamic mechanical properties while keeping thickness constant. Hybrid face sheets panels with three lay-up configurations of [G2C2G2H̅]s, [GCG2CGH̅]s, [CG4CH̅]s and non-hybrid configurations …
Smartphone Color Error Analysis, Mackenna Hawes
Smartphone Color Error Analysis, Mackenna Hawes
The Journal of Purdue Undergraduate Research
No abstract provided.
Liquid Nitrogen Shrink-Fitting Process, Natalie Harvey
Liquid Nitrogen Shrink-Fitting Process, Natalie Harvey
The Journal of Purdue Undergraduate Research
No abstract provided.
Upconversion Photoluminescence Of Monolayer Wse2 With Biaxial Strain Tuning, Shrawan Roy, Jie Gao, Xiaodong Yang
Upconversion Photoluminescence Of Monolayer Wse2 With Biaxial Strain Tuning, Shrawan Roy, Jie Gao, Xiaodong Yang
Mechanical and Aerospace Engineering Faculty Research & Creative Works
Mechanical strain can be used to tune the optical properties of monolayer transition metal dichalcogenides (1L-TMDs). Here, up conversion photoluminescence (UPL) from 1L-WSe2 flakes is tuned with biaxial strain induced by cruciform bending and indentation method. It is found that the peak position of UPL is redshifted by around 24 nm as the applied biaxial strain increases from 0% to 0.51%. At the same time, the UPL intensity increases exponentially for the up-conversion energy difference that lies within a broad range between −157 meV to −37 meV. The observed linear and sublinear power dependence of UPL emission in 1L-WSe …
Thermal Runaway Analysis And Cooling Strategies For Nmc 523 Li-Ion Battery Packs Using Pcm, Heat Pipes, And Air Cooling, Vijethvardhan Singh
Thermal Runaway Analysis And Cooling Strategies For Nmc 523 Li-Ion Battery Packs Using Pcm, Heat Pipes, And Air Cooling, Vijethvardhan Singh
Master's Theses
The growing demand for electric vehicles (EVs) necessitates efficient thermal management of lithium-ion batteries (LIBs), especially NMC 523 cells. This thesis investigates thermal runaway (TR) mechanisms and evaluates cooling strategies to mitigate overheating risks. Using ANSYS Fluent, the TR of four cells in series was simulated and validated with Jun Wu et al.'s experimental data, achieving an error margin below 10%. Peak temperatures reached 1,126°C in the first cell, with delayed propagation in adjacent cells. Sensitivity analysis of voltage, current, and state of charge (SOC) under varying C-rates was performed using a multi-scale multi-domain (MSMD) battery model. A logarithmic voltage …
Analysis And Reflections On Key Platform Facilities Construction Of Global Biomanufacturing Industry, Xiaoyan Wu, Fang Chen, Yaoying Shan, Anjing Lu
Analysis And Reflections On Key Platform Facilities Construction Of Global Biomanufacturing Industry, Xiaoyan Wu, Fang Chen, Yaoying Shan, Anjing Lu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Biomanufacturing, an emerging production method, is becoming a significant trend in global economic development and has garnered widespread international attention. Platform facilities are vital to the biomanufacturing industry’s development, serving as both the foundation for technological innovation and the bridge between research outcomes and practical applications. This study analyzes three key types of platform facilities and their operational mechanisms: technology innovation platforms (exemplified by the U.S. Agile BioFoundry), pilot-scale platforms (represented by European Bio Base Europe Pilot Plant), and industry incubation platforms (illustrated by the UK SynbiCITE). Drawing from these successful examples and examining China’s current platform infrastructure, this paper …
Implantation Of A Capsular Tension Ring During Cataract Surgery Attenuates Predicted Remodeling Of The Post-Surgical Lens Capsule Along The Visual Axis, Kurt A. Ameku, Caleb C. Berggren, Ryan M. Pedrigi
Implantation Of A Capsular Tension Ring During Cataract Surgery Attenuates Predicted Remodeling Of The Post-Surgical Lens Capsule Along The Visual Axis, Kurt A. Ameku, Caleb C. Berggren, Ryan M. Pedrigi
Department of Mechanical and Materials Engineering: Faculty Publications
Introduction: Cataract surgery permanently alters the mechanical environment of the lens capsule by placing a hole in the anterior portion and implanting an intraocular lens (IOL) that has a very different geometry from the native lens. We hypothesized that implant configuration and mechanical interactions with the post-surgical lens capsule play a key role in determining long-term fibrotic remodeling.
Methods: We developed the first finite element-growth and remodeling (FE-G&R) model of the post-surgical lens capsule to evaluate how implantation of an IOL with and without a capsular tension ring (CTR) impacted evolving lens capsule mechanics and associated fibrosis over …
Effects Of Organic Surface Contamination On The Mass Accommodation Coefficient Of Water: A Molecular Dynamics Study, Jordan Hartfield, Eric Bird, Zhi Liang
Effects Of Organic Surface Contamination On The Mass Accommodation Coefficient Of Water: A Molecular Dynamics Study, Jordan Hartfield, Eric Bird, Zhi Liang
Mechanical and Aerospace Engineering Faculty Research & Creative Works
The mass accommodation coefficient (MAC), a parameter that quantifies the possibility of a phase change to occur at a liquid-vapor interface, can strongly affect the evaporation and condensation rates at a liquid surface. Due to the various challenges in experimental determination of the MAC, molecular dynamics (MD) simulations have been widely used to study the MAC on liquid surfaces with no impurities or contaminations. However, experimental studies show that airborne hydrocarbons from various sources can adsorb on liquid surfaces and alter the liquid surface properties. In this work, therefore, we study the effects of organic surface contamination, which is immiscible …
Research On An Improved Cotton Cleaner Unit, Muzaffar Djurayev, Sherqul Hakimov, Ilhom Abbazov, Rashid Kaldybaev
Research On An Improved Cotton Cleaner Unit, Muzaffar Djurayev, Sherqul Hakimov, Ilhom Abbazov, Rashid Kaldybaev
Technical science and innovation
This article analyzes the results of changes to the working parts of a cotton cleaning unit from small and large impurities. It is known that the UXK installation uses continuous cleaning technology, that is, the cotton entering the purifier is cleaned in all its cleaning sections and then transferred to another process. In these sections, pieces of cotton wool from the separated waste are regenerated in a separate drum. Existing purifier suppliers use a manually operated mechanical system to monitor its performance. These factors do not make it possible to control the cleaning process when the quality indicators of cotton …
Polymerizing Actin Regulates Myosin-Independent Mechanosensing By Modulating Actin Elasticity And Flow Fluctuation, Nikhil Mittal, Etienne Michels, Kathleen Pakenas, Shaina P. Royer-Weeden, Sangyoon J. Han
Polymerizing Actin Regulates Myosin-Independent Mechanosensing By Modulating Actin Elasticity And Flow Fluctuation, Nikhil Mittal, Etienne Michels, Kathleen Pakenas, Shaina P. Royer-Weeden, Sangyoon J. Han
Michigan Tech Publications
The stiffness of the extracellular matrix induces differential tension within integrin-based adhesions. However, it has been unclear if the stiffness-dependent differential tension is induced solely by myosin activity. Here, we report that in the absence of myosin contractility, 3T3 fibroblasts still transmit stiffness-dependent differential levels of traction. This myosin-independent differential traction is regulated by polymerizing actin assisted by actin nucleators Arp2/3 and formin where formin has stronger contribution than Arp2/3. Interestingly, we report a four-fold reduction in traction of cells when both Arp2/3 and myosin were inhibited, compared to cells with only myosin inhibition, while there was only a slight …
Myosin-Independent Stiffness Sensing By Fibroblasts Is Regulated By The Viscoelasticity Of Flowing Actin, Nikhil Mittal, Etienne B. Michels, Andrew E. Massey, Yunxiu Qiu, Shaina P. Royer-Weeden, Bryan R. Smith, Alexander X. Cartagena-Rivera, Sangyoon J. Han
Myosin-Independent Stiffness Sensing By Fibroblasts Is Regulated By The Viscoelasticity Of Flowing Actin, Nikhil Mittal, Etienne B. Michels, Andrew E. Massey, Yunxiu Qiu, Shaina P. Royer-Weeden, Bryan R. Smith, Alexander X. Cartagena-Rivera, Sangyoon J. Han
Michigan Tech Publications
The stiffness of the extracellular matrix induces differential tension within integrin-based adhesions, triggering differential mechanoresponses. However, it has been unclear if the stiffness-dependent differential tension is induced solely by myosin activity. Here, we report that in the absence of myosin contractility, 3T3 fibroblasts still transmit stiffness-dependent differential levels of traction. This myosin-independent differential traction is regulated by polymerizing actin assisted by actin nucleators Arp2/3 and formin where formin has a stronger contribution than Arp2/3 to both traction and actin flow. Intriguingly, despite only slight changes in F-actin flow speed observed in cells with the combined inhibition of Arp2/3 and myosin …
Optimum Design Of Metallic And Plastic Cylindrical Gears Using Naturally-Inspired Algorithms: A Review, Marah Elsiedy, Hesham Hegazi, Ahmed Elkassas, Abdelhameed Zayed
Optimum Design Of Metallic And Plastic Cylindrical Gears Using Naturally-Inspired Algorithms: A Review, Marah Elsiedy, Hesham Hegazi, Ahmed Elkassas, Abdelhameed Zayed
Journal of Engineering Research
Abstract- Nowadays, several machinery and vehicles utilize mechanical elements which transmit power ranges from low, middle, and high levels depending on the type of equipment needed. Gears are the most influential design elements on any process during the running of a specific application, moreover engineers tried to obtain the optimality of a gear design which is a more compact, reliable- long service with simply operating features by following a systematic calculation of the mathematical model from standards and handbooks, however this process doesn't give the optimal design of the gears. Optimization techniques have been added to the design process for …
Enhancing The Performance Of Conventional Solar Still Using The Nano-Doped Paint (Ndp) Coating, Hagar Alm-Eldin Bastawissi Prof.Dr, Nermin Elgendy Engineer, Ayman R. El-Tohamy
Enhancing The Performance Of Conventional Solar Still Using The Nano-Doped Paint (Ndp) Coating, Hagar Alm-Eldin Bastawissi Prof.Dr, Nermin Elgendy Engineer, Ayman R. El-Tohamy
Journal of Engineering Research
Nations are throughout the entire globe continuously confronting the problem of potable water shortage. Recently, it has been thought that using solar energy to desalinate brackish water offers a practical answer to the world's water crises. The output of these stills, is meager, and academics haven't done much to boost it in any way. Solar distillers have been proposed as an efficient method to produce potable water. In recent years, saltwater has produced drinking water by various ways. The efficiency of a solar distiller is significantly influenced by various factors, most important factor of them is the absorber surface. In …
Numerical Study Of The Effect Of Long Shroud Diffuser With And Without Plate Obstacle On The Performance Of Savonius Wind Turbine, Alsaied Khalil Mahmoud, Mohamed Mahgoub Bassuoni, Mohamed Fawzy Obiaa, Ahmed Mostafa Khaira
Numerical Study Of The Effect Of Long Shroud Diffuser With And Without Plate Obstacle On The Performance Of Savonius Wind Turbine, Alsaied Khalil Mahmoud, Mohamed Mahgoub Bassuoni, Mohamed Fawzy Obiaa, Ahmed Mostafa Khaira
Journal of Engineering Research
This study presents the three-dimensional (3-D) numerical analysis of the influence of the plate obstacle installed at the entrance of the long flanged diffuser on the simple Savonius rotor performance by ANSYS 2022 R1. In the beginning, the 3-D numerical model is validated using the sst k-ω turbulence model with the previous published experimental results at the same conditions, and they are in good agreement with each other. The numerical results indicate the remarkable enhancement of the rotor performance at a tip speed ratio of 0 to 0.7 by using a flanged diffuser with a plate obstacle. The shrouded diffuser …
The Influence Of Using Hho With Sunflower And Soybean Oil Biodiesel/Diesel Blend On Pcci Engine Characteristics, Mai H. Aboubakr, Medhat Elkelawy Prof. Dr., Hagar Alm-Eldin Bastawissi Prof. Dr., Ayman R. El-Tohamy Dr.
The Influence Of Using Hho With Sunflower And Soybean Oil Biodiesel/Diesel Blend On Pcci Engine Characteristics, Mai H. Aboubakr, Medhat Elkelawy Prof. Dr., Hagar Alm-Eldin Bastawissi Prof. Dr., Ayman R. El-Tohamy Dr.
Journal of Engineering Research
This research studies the influence of various blends of sunflower and soybean oil biodiesel with diesel fuel on premixed charge compression engine characteristics, including performance and exhaust emissions, and also investigates the impact caused by oxyhydrogen gas addition on them. The experiments were carried out on a single cylinder PCCI engine which utilizing eight blends of the fuels. Conventional diesel, B20D80, B40D60, B60D40, B80D20, B40D60 + 5 LPM HHO, B40D60 + 10 LPM HHO, and B40D60 + 15 LPM HHO have been used to obtain performance and exhaust emissions characteristics. The hydrogen peroxide additive has introduced into the engine manifold …
Performance Of Photocatalytic Oxidizing Air Cleaners In Different Experimental Setups – A Review, Giovanni Cerrato, Nelson Fumo
Performance Of Photocatalytic Oxidizing Air Cleaners In Different Experimental Setups – A Review, Giovanni Cerrato, Nelson Fumo
Mechanical Engineering Faculty Publications and Presentations
Photocatalytic oxidizing (PCO) air cleaners are offered for the abatement of gaseous pollutants (i.e., Volatile Organic Compounds or VOCs). However, due to a lack of testing standards, the overall characterization of the technology's effectiveness has been met with conflicting results. Different studies use varying experimental setups, test conditions, and different PCO air cleaner designs. According to the literature, the majority of testing has been in controlled laboratory setups with favorable conditions. As PCO air cleaner testing is scaled up to more realistic environments and conditions, the PCO removal efficiency tends to significantly decrease. The differences in removal efficiency can be …
Engineering Neurotoxin-Functionalized Exosomes For Targeted Delivery To The Peripheral Nervous System, Mena Asha Krishnan, Olawale A. Alimi, Tianshu Pan, Mitchell Kuss, Zeljka Korade, Guoku Hu, Bo Liu, Bin Duan
Engineering Neurotoxin-Functionalized Exosomes For Targeted Delivery To The Peripheral Nervous System, Mena Asha Krishnan, Olawale A. Alimi, Tianshu Pan, Mitchell Kuss, Zeljka Korade, Guoku Hu, Bo Liu, Bin Duan
Department of Mechanical and Materials Engineering: Faculty Publications
The administration of therapeutics to peripheral nerve tissue is challenging due to the complexities of peripheral neuroanatomy and the limitations imposed by the blood–nerve barrier (BNB). Therefore, there is a pressing need to enhance delivery effectiveness and implement targeted delivery methods. Recently, erythrocyte-derived exosomes (Exos) have gained widespread attention as biocompatible vehicles for therapeutics in clinical applications. However, engineering targeted Exos for the peripheral nervous system (PNS) is still challenging. This study aims to develop a targeted Exo delivery system specifically designed for presynaptic terminals of peripheral nerve tissue. The clostridium neurotoxin, tetanus toxin-C fragment (TTC), was tethered to the …
Stick-Fixed Maneuver Points In Roll, Pitch, And Yaw And Associated Handling Qualities, Benjamin C. Moulton, Troy A. Abraham, Douglas F. Hunsaker
Stick-Fixed Maneuver Points In Roll, Pitch, And Yaw And Associated Handling Qualities, Benjamin C. Moulton, Troy A. Abraham, Douglas F. Hunsaker
Mechanical and Aerospace Engineering Student Publications and Presentations
The stick-fixed pitch maneuver point is an important measure of aircraft longitudinal dynamic response and handling quality characteristics, and includes effects of both aerodynamic and inertia properties of the aircraft about the pitch axis. In the present work, the existence of stick-fixed roll and yaw maneuver points is demonstrated, which are determined from the lateral forces, moments, and inertial properties of the aircraft. These stick-fixed roll and yaw maneuver points are directly related to the predicted lateral handling qualities. Example results are included for several aircraft that demonstrate the importance of this parameter when predicting the dynamic response of the …
Yap Mechanotransduction Under Cyclic Mechanical Stretch Loading For Mesenchymal Stem Cell Osteogenesis Is Regulated By Rock, Eunju Kim, Brandon D. Riehl, Tasneem Bouzid, Ruiguo Yang, Bin Duan, Henry J. Donahue, Jung Yul Lim
Yap Mechanotransduction Under Cyclic Mechanical Stretch Loading For Mesenchymal Stem Cell Osteogenesis Is Regulated By Rock, Eunju Kim, Brandon D. Riehl, Tasneem Bouzid, Ruiguo Yang, Bin Duan, Henry J. Donahue, Jung Yul Lim
Department of Mechanical and Materials Engineering: Faculty Publications
While yes-associated protein (YAP) is now recognized as a potent mechanosensitive transcriptional regulator to affect cell growth and differentiation including the osteogenic transcription of mesenchymal stem cells (MSCs), most studies have reported the YAP mechanosensing of static mechanophysical cues such as substrate stiffness. We tested MSC response to dynamic loading, i.e., cyclic mechanical stretching, and assessed YAP mechanosensing and resultant MSC osteogenesis. We showed that cyclic stretching at 10% strain and 1 Hz frequency triggered YAP nuclear import in MSCs. YAP phosphorylation at S127 and S397, which is required for YAP cytoplasmic retention, was suppressed by cyclic stretch. We also …
Improvement Of Convective Drying Equipment, A Ponasenko, Jasur Safarov, Shaxnoza Sultanova
Improvement Of Convective Drying Equipment, A Ponasenko, Jasur Safarov, Shaxnoza Sultanova
Technical science and innovation
Drying of agricultural raw materials is an energy-consuming but integral process. Therefore, increasing the efficiency of drying and improving the quality indicators of dried material at minimum material and energy costs is relevant for producers of agricultural products. By present time numerous researches on improvement of constructions and processes of work of dryers providing satisfactory parameters of energy saving have been carried out. In some scientific materials it is shown that the use of generative gas and straw as fuel allows to reduce energy costs for the drying process in the fluidised bed dryer by 10-30%, the quality of seeds …
Existing Methods For Monitoring Power Autotransformers, Nurali Berdiyorovich Pyrmatov, Dilafruz Rustamjon Qizi Abdullabekova
Existing Methods For Monitoring Power Autotransformers, Nurali Berdiyorovich Pyrmatov, Dilafruz Rustamjon Qizi Abdullabekova
Technical science and innovation
autotransformers, methods, diagnostics, efficiency, monitoring.Particular attention is given to analyzing the gas composition of transformer oil, which is a sensitive indicator of various defects such as thermal breakdown and heating. In addition, methods based on the measurement of external magnetic field strength are discussed. This technique provides a unique opportunity to detect magnetic anomalies associated with possible defects in the structural components of the transformer. The article emphasizes that successful monitoring requires an integrated approach, combining different techniques. The authors analyze the advantages and limitations of each method and offer practical recommendations for integrating these methods into maintenance systems. In …