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Full-Text Articles in Engineering

Room Temperature Two-Dimensional Electron Gas Scattering Time, Effective Mass, And Mobility Parameters In AlXGa1−XN/Gan Heterostructures (0.07 ≤ X ≤ 0.42), Sean Knight, Steffen Richter, Alexis Papamichail, Philipp Kühne, Nerijus Armakavicius, Shiqi Guo, Axel R. Persson, Vallery Stanishev, Viktor Rindert, Per O. Å. Persson, Plamen P. Paskov, Mathias Schubert, Vanya Darakchieva Nov 2023

Room Temperature Two-Dimensional Electron Gas Scattering Time, Effective Mass, And Mobility Parameters In AlXGa1−XN/Gan Heterostructures (0.07 ≤ X ≤ 0.42), Sean Knight, Steffen Richter, Alexis Papamichail, Philipp Kühne, Nerijus Armakavicius, Shiqi Guo, Axel R. Persson, Vallery Stanishev, Viktor Rindert, Per O. Å. Persson, Plamen P. Paskov, Mathias Schubert, Vanya Darakchieva

Department of Electrical and Computer Engineering: Faculty Publications

AlxGa1-xN/GaN high-electron-mobility transistor (HEMT) structures are key components in electronic devices operating at gigahertz or higher frequencies. In order to optimize such HEMT structures, understanding their electronic response at high frequencies and room temperature is required. Here, we present a study of the room temperature free charge carrier properties of the two-dimensional electron gas (2DEG) in HEMT structures with varying Al content in the AlxGa1-xN barrier layers between x = 0:07 and x = 0:42. We discuss and compare 2DEG sheet density, mobility, effective mass, sheet resistance, and scattering times, …


Study On Debinding And Sintering Conditions In Extrusion-Based Additive Manufacturing Of 316l And 316l + Cu, Jean-François Silvain, Daniel Lincoln Gifford, Sébastien Fourcade, Laurent Cuzacq, Jean-Luc Grosseau-Poussard, Catherine Debiemme-Chouvy, Nicolas Tessier Doyen, Yongfeng Lu Nov 2023

Study On Debinding And Sintering Conditions In Extrusion-Based Additive Manufacturing Of 316l And 316l + Cu, Jean-François Silvain, Daniel Lincoln Gifford, Sébastien Fourcade, Laurent Cuzacq, Jean-Luc Grosseau-Poussard, Catherine Debiemme-Chouvy, Nicolas Tessier Doyen, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

This study investigates the use of a methylcellulose binder in extrusion additive manufacturing of 316L as an alternative to common wax-based binders. Various quantities of copper (Cu) powder were also added in the paste composition to attempt to reduce the sintering temperature by promoting persistent liquid phase sintering. Debinding experiments were conducted under different temperatures and dwell times using argon (Ar), Ar/5%H2, and Ar/1%O2 atmospheres. Debinding reduced carbon (C) content to 0.032 wt.% by using a two-step debinding process of Ar/5%H2 and Ar/1%O2 thermal treatments. Using this debinding process, sintering was conducted at 1200 o …


Nitrogen Radiofrequency Plasma Treatment Of Graphene, Antoine Bident, Nathalie Caillault, Florence Delange, Christine Labrugere, Guillaume Aubert, Cyril Aymonier, Etienne Durand, Alain Demourgues, Yongfeng Lu, Jean-François Silvain Oct 2023

Nitrogen Radiofrequency Plasma Treatment Of Graphene, Antoine Bident, Nathalie Caillault, Florence Delange, Christine Labrugere, Guillaume Aubert, Cyril Aymonier, Etienne Durand, Alain Demourgues, Yongfeng Lu, Jean-François Silvain

Department of Electrical and Computer Engineering: Faculty Publications

The incorporation of nitrogen (N) atoms into a graphitic network such as graphene (Gr) remains a major challenge. However, even if the insertion mechanisms are not yet fully understood, it is certain that the modification of the electrical properties of Gr is possible according to the configuration adopted. Several simulations work, notably using DFT, have shown that the incorporation of N in Gr can induce an increase in the electrical conductivity and N acts as an electron donor; this increase is linked to the amount of N, the sp2/sp3 carbon configuration, and the nature of C-N bonding. …


Detection Of Cancer-Associated Gene Mutations In Urinary Cell-Free Dna Among Prostate Cancer Patients In South Africa, Dada Oluwaseyi Temilola, Martha Wium, Juliano Paccez, Azola Samkele Salukazana, Solomon O. Rotimi, Hasan H. Otu, Giuseppina M. Carbone, Lisa Kaestner, Stefano Cacciatore, Luiz Fernando Zerbini Sep 2023

Detection Of Cancer-Associated Gene Mutations In Urinary Cell-Free Dna Among Prostate Cancer Patients In South Africa, Dada Oluwaseyi Temilola, Martha Wium, Juliano Paccez, Azola Samkele Salukazana, Solomon O. Rotimi, Hasan H. Otu, Giuseppina M. Carbone, Lisa Kaestner, Stefano Cacciatore, Luiz Fernando Zerbini

Department of Electrical and Computer Engineering: Faculty Publications

Prostate cancer (PCa) is the most common cause of cancer death among African men. The presence of tumor-specific variations in cell-free DNA (cfDNA), such as mutations, microsatellite instability, and DNA methylation, has been explored as a source of biomarkers for cancer diagnosis. In this study, we investigated the diagnostic role of cfDNA among South African PCa patients. We performed whole exome sequencing (WES) of urinary cfDNA. We identified a novel panel of 31 significantly deregulated somatic mutated genes between PCa and benign prostatic hyperplasia (BPH). Additionally, we performed whole-genome sequencing (WGS) on matching PCa and normal prostate tissue in an …


Laser-Direct-Drive Fusion Target Design With A High-Z Gradient-Density Pusher Shell, S. S. Hu, L. Ceurvorst, J. L. Peebles, A. Mao, P. Li, Yongfeng Lu, A. Shvydky, V. N. Goncharov, R. Epstein, K. A. Nichols, R. M. N. Goshadze, M. Ghosh, J. Hinz, V. V. Karasiev, S. Zhang, N. R. Shaffer, D. I. Mihaylov, J. Cappelletti, D. R. Harding, C. K. Li, E. M. Campbell, R. C. Shah, T. J. B. Collins, S. P. Regan, C. Deeney Sep 2023

Laser-Direct-Drive Fusion Target Design With A High-Z Gradient-Density Pusher Shell, S. S. Hu, L. Ceurvorst, J. L. Peebles, A. Mao, P. Li, Yongfeng Lu, A. Shvydky, V. N. Goncharov, R. Epstein, K. A. Nichols, R. M. N. Goshadze, M. Ghosh, J. Hinz, V. V. Karasiev, S. Zhang, N. R. Shaffer, D. I. Mihaylov, J. Cappelletti, D. R. Harding, C. K. Li, E. M. Campbell, R. C. Shah, T. J. B. Collins, S. P. Regan, C. Deeney

Department of Electrical and Computer Engineering: Faculty Publications

Laser-direct-drive fusion target designs with solid deuterium-tritium (DT) fuel, a high-Z gradient-density pusher shell (GDPS), and a Au-coated foam layer have been investigated through both 1D and 2D radiationhydrodynamic simulations. Compared with conventional low-Z ablators and DT-push-on-DT targets, these GDPS targets possess certain advantages of being instability-resistant implosions that can be high adiabat (α ≽ 8) and low hot-spot and pusher-shell convergence (CRhs ≈22 and CRPS ≈17), and have a low implosion velocity (vimp < 3 × 107 cm/s). Using symmetric drive with laser energies of 1.9 to 2.5 MJ, 1D LILAC simulations of these GDPS implosions can result …


Aptamer-Based Proteomics Measuring Preoperative Cerebrospinal Fluid Protein Alterations Associated With Postoperative Delirium, Simon T. Dillon, Sarinnapha M. Vasunilashorn, Hasan H. Otu, Long Ngo, Tamara Fong, Xuesong Gu, Michele Cavallari, Alexandra Touroutoglou, Mouhsin Shafi, Sharon K. Inouye, Zhongcong Xie, Edward R. Marcantonio, Towia A. Libermann Sep 2023

Aptamer-Based Proteomics Measuring Preoperative Cerebrospinal Fluid Protein Alterations Associated With Postoperative Delirium, Simon T. Dillon, Sarinnapha M. Vasunilashorn, Hasan H. Otu, Long Ngo, Tamara Fong, Xuesong Gu, Michele Cavallari, Alexandra Touroutoglou, Mouhsin Shafi, Sharon K. Inouye, Zhongcong Xie, Edward R. Marcantonio, Towia A. Libermann

Department of Electrical and Computer Engineering: Faculty Publications

Delirium is a common postoperative complication among older patients with many adverse outcomes. Due to a lack of validated biomarkers, prediction and monitoring of delirium by biological testing is not currently feasible. Circulating proteins in cerebrospinal fluid (CSF) may reflect biological processes causing delirium. Our goal was to discover and investigate candidate protein biomarkers in preoperative CSF that were associated with the development of postoperative delirium in older surgical patients. We employed a nested case–control study design coupled with high multiplex affinity proteomics analysis to measure 1305 proteins in preoperative CSF. Twenty-four matched delirium cases and non-delirium controls were selected …


Integrating Glycolysis, Citric Acid Cycle, Pentose Phosphate Pathway, And Fatty Acid Beta‑Oxidation Into A Single Computational Model, Sylwester M. Kloska, Krzysztof Pałczyński, Tomasz Marciniak, Tomasz Talaśka, Beata J. Wysocki, Paul H. Davis, Tadeusz A. Wysocki Sep 2023

Integrating Glycolysis, Citric Acid Cycle, Pentose Phosphate Pathway, And Fatty Acid Beta‑Oxidation Into A Single Computational Model, Sylwester M. Kloska, Krzysztof Pałczyński, Tomasz Marciniak, Tomasz Talaśka, Beata J. Wysocki, Paul H. Davis, Tadeusz A. Wysocki

Department of Electrical and Computer Engineering: Faculty Publications

The metabolic network of a living cell is highly intricate and involves complex interactions between various pathways. In this study, we propose a computational model that integrates glycolysis, the pentose phosphate pathway (PPP), the fatty acids beta-oxidation, and the tricarboxylic acid cycle (TCA cycle) using queueing theory. The model utilizes literature data on metabolite concentrations and enzyme kinetic constants to calculate the probabilities of individual reactions occurring on a microscopic scale, which can be viewed as the reaction rates on a macroscopic scale. However, it should be noted that the model has some limitations, including not accounting for all the …


Potential Of Mirnas In Plasma Extracellular Vesicle For The Stratification Of Prostate Cancer In A South African Population, Dada Oluwaseyi Temilola, Martha Wium, Juliano Paccez, Azola Samkele Salukazana, Hasan H. Otu, Giuseppina M. Carbone, Lisa Kaestner, Stefano Cacciatore, Luiz Fernando Zerbini Aug 2023

Potential Of Mirnas In Plasma Extracellular Vesicle For The Stratification Of Prostate Cancer In A South African Population, Dada Oluwaseyi Temilola, Martha Wium, Juliano Paccez, Azola Samkele Salukazana, Hasan H. Otu, Giuseppina M. Carbone, Lisa Kaestner, Stefano Cacciatore, Luiz Fernando Zerbini

Department of Electrical and Computer Engineering: Faculty Publications

Prostate cancer (PCa) is the most common cause of cancer death among African men. The analysis of microRNAs (miRNAs) in plasma extracellular vesicles (EVs) can be utilized as a non-invasive tool for the diagnosis of PCa. In this study, we used small RNA sequencing to profile miRNAs cargo in plasma EVs from South African PCa patients. We evaluated the differential expression of miRNAs between low and high Gleason scores in the plasma EVs of South African patients and in the prostatic tissue from data available in the Cancer Genome Atlas (TCGA) Data Portal. We identified 7 miRNAs differently expressed in …


Integration Of Meta-Multi-Omics Data Using Probabilistic Graphs And External Knowledge, Handan Can, Sree K. Chanumolu, Barbara D. D., Sophie Alvarez, Michael J. Naldrett, Gülhan Ünlü, Hasan H. Otu Aug 2023

Integration Of Meta-Multi-Omics Data Using Probabilistic Graphs And External Knowledge, Handan Can, Sree K. Chanumolu, Barbara D. D., Sophie Alvarez, Michael J. Naldrett, Gülhan Ünlü, Hasan H. Otu

Department of Electrical and Computer Engineering: Faculty Publications

Multi-omics has the promise to provide a detailed molecular picture of biological systems. Although obtaining multi-omics data is relatively easy, methods that analyze such data have been lagging. In this paper, we present an algorithm that uses probabilistic graph representations and external knowledge to perform optimal structure learning and deduce a multifarious interaction network for multi-omics data from a bacterial community. Kefir grain, a microbial community that ferments milk and creates kefir, represents a self-renewing, stable, natural microbial community. Kefir has been shown to have a wide range of health benefits. We obtained a controlled bacterial community using the two …


A Unified Switched Nonlinear Dynamic Model Of An Electric Vehicle For Performance Evaluation, Dibyendu Khan, Kuntal Mandal, Anjan Kumar Ray, Abdelali El Aroudi Jul 2023

A Unified Switched Nonlinear Dynamic Model Of An Electric Vehicle For Performance Evaluation, Dibyendu Khan, Kuntal Mandal, Anjan Kumar Ray, Abdelali El Aroudi

Department of Electrical and Computer Engineering: Faculty Publications

The advanced modeling and estimation of overall system dynamics play a vital role in electric vehicles (EVs), as the selection of components in the powertrain and prediction of performance are the key market qualifiers. The state-space averaged model and small-signal transfer function model are useful for assessing long-term behavior in system-level analysis and for designing the controller parameters, respectively. Both models take less computation time but ignore the high-frequency switching dynamics. Therefore, these two models could be impractical for the development and testing of EV prototypes. On the other hand, the multi-domain model in available simulation tools gives in-depth information …


An Ai-Based Intervention For Improving Undergraduate Stem Learning, Mohammad Rashedul Hasan, Bilal Khan Jul 2023

An Ai-Based Intervention For Improving Undergraduate Stem Learning, Mohammad Rashedul Hasan, Bilal Khan

Department of Electrical and Computer Engineering: Faculty Publications

We present results from a small-scale randomized controlled trial that evaluates the impact of just-in-time interventions on the academic outcomes of N = 65 undergraduate students in a STEM course. Intervention messaging content was based on machine learning forecasting models of data collected from 537 students in the same course over the preceding 3 years. Trial results show that the intervention produced a statistically significant increase in the proportion of students that achieved a passing grade. The outcomes point to the potential and promise of just-in-time interventions for STEM learning and the need for larger fully-powered randomized controlled trials.


Generation Of Vector Vortex Wave Modes In Cylindrical Waveguides, Md Khadimul Islam, Pawan Gaire, Arjuna Madanayake, Shubhendu Bhardwaj Jul 2023

Generation Of Vector Vortex Wave Modes In Cylindrical Waveguides, Md Khadimul Islam, Pawan Gaire, Arjuna Madanayake, Shubhendu Bhardwaj

Department of Electrical and Computer Engineering: Faculty Publications

In this paper, we propose a method to generate Vector Vortex Modes (VVM) inside a metallic cylindrical waveguide at microwave frequencies and demonstrate the experimental validation of the concept. Vector vortex modes of EM waves can carry both spin and orbital angular momentum as they propagate within a tubular medium. The existence of such waves in tubular media can be beneficial to wireless communication in such structures. These waves can carry different orbital angular momentum and spin angular momentum, and therefore, they feature the ability to carry multiple orthogonal modes at the same frequency due to spatial structure of the …


A Flexible Ot Testbed For Evaluating On-Device Implementations Of Iec-61850 Goose, Matthew Boeding, Michael Hempel, Hamid Sharif, Juan Lopez Jr., Kalyan Perumalla Jun 2023

A Flexible Ot Testbed For Evaluating On-Device Implementations Of Iec-61850 Goose, Matthew Boeding, Michael Hempel, Hamid Sharif, Juan Lopez Jr., Kalyan Perumalla

Department of Electrical and Computer Engineering: Faculty Publications

The growing convergence of Information Technology and Operational Technology has enhanced communication and visibility across power grids. This, coupled with the growing use of Distributed Energy Resources in power grids, has enhanced the grid capabilities while also creating a larger attack surface for malicious actors. A common protocol vulnerable to these attacks is the IEC-61850 GOOSE protocol due to its low-latency requirements, multicast packet delivery method, and lack of encryption. In this paper, we evaluate the security implications of different hardware implementations of this protocol by contrasting device response and recovery of two commercial off-the-shelf Intelligent Electronic Devices from separate …


Cometrics: A New Software Tool For Behavior‑Analytic Clinicians And Machine Learning Researchers, Walker S. Arce, Seth G. Walker, Morgan L. Hurtz Jun 2023

Cometrics: A New Software Tool For Behavior‑Analytic Clinicians And Machine Learning Researchers, Walker S. Arce, Seth G. Walker, Morgan L. Hurtz

Department of Electrical and Computer Engineering: Faculty Publications

Cometrics is a Microsoft Windows compatible clinical tool for the collection and recording of frequency- and duration-based target behaviors, physiological signals, and video data. This software package is designed to record in-vivo observational and physiological data. In addition, we have included features that allow observers to capture video from real-time camera feeds and import saved video for retroactive data collection. By using Microsoft Excel-based spreadsheets, also called keystroke files, assessment and treatment sessions are exported into a single document using the click of a button. Integrated interobserver agreement metrics allow comparisons across primary and reliability observers, with the output exported …


Guest Editorial: Special Issue On Green Iot For Future Space–Air–Ground–Ocean-Integrated Networks And Applications, Bo Rong, Mohamed Cheriet, Jon Montalban, Lei Shu, Yi Qian Jun 2023

Guest Editorial: Special Issue On Green Iot For Future Space–Air–Ground–Ocean-Integrated Networks And Applications, Bo Rong, Mohamed Cheriet, Jon Montalban, Lei Shu, Yi Qian

Department of Electrical and Computer Engineering: Faculty Publications

The Internet of Things (IoT) plays a critical role in enabling the seamless integration of disparate devices. Future IoT will rapidly expand its coverage to offer future worldwide omnipresent applications and services by merging communications in diverse spatial domains to build the space–air–ground–ocean-integrated network (SAGOI-Net). SAGOI-Net will include a significant number of battery-powered network nodes, such as satellites, unmanned vehicles, and underwater devices, due to the extremely vast geographic reach and dynamics in free space. Given the battery limitations, high-energy-efficiency communications and networking will be critical to the future system. Green SAGOI-Net seeks to not only bring ubiquitous connectivity to …


Anticancer Activities Of Tetra-, Penta-, And Hexacyclic Phenothiazines Modified With Quinoline Moiety., Małgorzata Jel, Beata Morak-Młodawska, Rafał Korlacki May 2023

Anticancer Activities Of Tetra-, Penta-, And Hexacyclic Phenothiazines Modified With Quinoline Moiety., Małgorzata Jel, Beata Morak-Młodawska, Rafał Korlacki

Department of Electrical and Computer Engineering: Faculty Publications

The quinoline molecule is a chemical motif showing a highly promising pharmacological potential. Its numerous derivatives introduced into medicine revolutionized in the treatment of many entities of disease. The presence of the quinoline system in the structure of phenothiazines made it possible to obtain new aza- and diazaphenothiazine derivatives that show promising anticancer potential. The aza-analogs of the phenothiazines are structurally modified phenothiazines by the substitution of one or both benzene rings in the phenothiazine ring system with various azine rings. This approach to the strategy of obtaining new substances with biological potential can be classified as molecular hybridization methods …


Study Of Lipophilicity And Adme Properties Of 1,9-Diazaphenothiazines With Anticancer Action, Beata Morak-Młodawska, Małgorzata Jeleń, Emilia Martula, Rafał Korlacki Apr 2023

Study Of Lipophilicity And Adme Properties Of 1,9-Diazaphenothiazines With Anticancer Action, Beata Morak-Młodawska, Małgorzata Jeleń, Emilia Martula, Rafał Korlacki

Department of Electrical and Computer Engineering: Faculty Publications

Lipophilicity is one of the key properties of a potential drug that determines the solubility, the ability to penetrate through cell barriers, and transport to the molecular target. It affects pharmacokinetic processes such as adsorption, distribution, metabolism, excretion (ADME). The 10-substituted 1,9-diazaphenothiazines show promising if not impressive in vitro anticancer potential, which is associated with the activation of the mitochondrial apoptosis pathway connected with to induction BAX, forming a channel in MOMP and releasing cytochrome c for the activation of caspases 9 and 3. In this publication, the lipophilicity of previously obtained 1,9-diazaphenothiazines was determined theoretically using various computer programs …


Study Of Lipophilicity And Adme Properties Of 1,9-Diazaphenothiazines With Anticancer Action, Beata Morak-Młodawska, Małgorzata Jeleń, Emilia Martula, Rafał Korlacki Apr 2023

Study Of Lipophilicity And Adme Properties Of 1,9-Diazaphenothiazines With Anticancer Action, Beata Morak-Młodawska, Małgorzata Jeleń, Emilia Martula, Rafał Korlacki

Department of Electrical and Computer Engineering: Faculty Publications

Lipophilicity is one of the key properties of a potential drug that determines the solubility, the ability to penetrate through cell barriers, and transport to the molecular target. It affects pharmacokinetic processes such as adsorption, distribution, metabolism, excretion (ADME). The 10-substituted 1,9-diazaphenothiazines show promising if not impressive in vitro anticancer potential, which is associated with the activation of the mitochondrial apoptosis pathway connected with to induction BAX, forming a channel in MOMP and releasing cytochrome c for the activation of caspases 9 and 3. In this publication, the lipophilicity of previously obtained 1,9-diazaphenothiazines was determined theoretically using various computer programs …


Artificial Neural Network-Based Prediction Assessment Of Wire Electric Discharge Machining Parameters For Smart Manufacturing, Itagi Vijayakumar Manoj, Sannayellappa Narendranath, Peter Madindwa Mashinini, Hargovind Soni, Shanay Rab, Shadab Ahmad, Ahatsham Hayat Mar 2023

Artificial Neural Network-Based Prediction Assessment Of Wire Electric Discharge Machining Parameters For Smart Manufacturing, Itagi Vijayakumar Manoj, Sannayellappa Narendranath, Peter Madindwa Mashinini, Hargovind Soni, Shanay Rab, Shadab Ahmad, Ahatsham Hayat

Department of Electrical and Computer Engineering: Faculty Publications

Artificial intelligence (AI), robotics, cybersecurity, the Industrial Internet of Things, and blockchain are some of the technologies and solutions that are combined to produce “smart manufacturing,” which is used to optimize manufacturing processes by creating and/or accepting data. In manufacturing, spark erosion technique such as wire electric discharge machining (WEDM) is a process that machines different hard-to-cut alloys. It is regarded as the solution for cutting intricate parts and materials that are resistant to conventional machining techniques or are required by design. In the present study, holes of different radii, i.e. 1, 3, and 5mm, have been cut on Nickelvac-HX. …


Deep Reinforcement Learning For Articulatory Synthesis In A Vowel-To-Vowel Imitation Task, Denis Shitov, Elena Pirogova, Tadeusz A. Wysocki, Margaret Lech Mar 2023

Deep Reinforcement Learning For Articulatory Synthesis In A Vowel-To-Vowel Imitation Task, Denis Shitov, Elena Pirogova, Tadeusz A. Wysocki, Margaret Lech

Department of Electrical and Computer Engineering: Faculty Publications

Articulatory synthesis is one of the approaches used for modeling human speech production. In this study, we propose a model-based algorithm for learning the policy to control the vocal tract of the articulatory synthesizer in a vowel-to-vowel imitation task. Our method does not require external training data, since the policy is learned through interactions with the vocal tract model. To improve the sample efficiency of the learning, we trained the model of speech production dynamics simultaneously with the policy. The policy was trained in a supervised way using predictions of the model of speech production dynamics. To stabilize the training, …


A Highly Efficient Broadband Multi-Functional Metaplate, Azhar Javed Satti, Muhammad Ashar Naveed, Isma Javed, Nasir Mahmood, Muhammad Zubair, Muhammad Qasim Mehmood, Yehia Massoud Feb 2023

A Highly Efficient Broadband Multi-Functional Metaplate, Azhar Javed Satti, Muhammad Ashar Naveed, Isma Javed, Nasir Mahmood, Muhammad Zubair, Muhammad Qasim Mehmood, Yehia Massoud

Department of Electrical and Computer Engineering: Faculty Publications

Due to the considerable potential of ultra-compact and highly integrated meta-optics, multi-functional metasurfaces have attracted great attention. The mergence of nanoimprinting and holography is one of the fascinating study areas for image display and information masking in meta-devices. However, existing methods rely on layering and enclosing, where many resonators combine various functions effectively at the expense of efficiency, design complication, and complex fabrication. To overcome these limitations, a novel technique for a tri-operational metasurface has been suggested by merging PB phase-based helicity-multiplexing and Malus's law of intensity modulation. To the best of our knowledge, this technique resolves the extreme-mapping issue …


Updated Perspectives On The Role Of Biomechanics In Copd: Considerations For The Clinician, Jennifer M. Yentes, Wai-Yan Liu, Kuan Zhang, Eric J. Markvicka, Stephen I. Rennard Oct 2022

Updated Perspectives On The Role Of Biomechanics In Copd: Considerations For The Clinician, Jennifer M. Yentes, Wai-Yan Liu, Kuan Zhang, Eric J. Markvicka, Stephen I. Rennard

Department of Electrical and Computer Engineering: Faculty Publications

Patients with chronic obstructive pulmonary disease (COPD) demonstrate extra-pulmonary functional decline such as an increased prevalence of falls. Biomechanics offers insight into functional decline by examining mechanics of abnormal movement patterns. This review discusses biomechanics of functional outcomes, muscle mechanics, and breathing mechanics in patients with COPD as well as future directions and clinical perspectives. Patients with COPD demonstrate changes in their postural sway during quiet standing compared to controls, and these deficits are exacerbated when sensory information (eg, eyes closed) is manipulated. If standing balance is disrupted with a perturbation, patients with COPD are slower to return to baseline …


Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan Sep 2022

Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan

Department of Electrical and Computer Engineering: Faculty Publications

Coronary artery disease (CAD) is one of the major cardiovascular diseases and represents the leading causes of global mortality. Developing new diagnostic and therapeutic approaches for CAD treatment are critically needed, especially for an early accurate CAD detection and further timely intervention. In this study, we successfully isolated human plasma small extracellular vesicles (sEVs) from four stages of CAD patients, that is, healthy control, stable plaque, non-ST-elevation myocardial infarction, and ST-elevation myocardial infarction. Surface-enhanced Raman scattering (SERS) measurement in conjunction with five machine learning approaches, including Quadratic Discriminant Analysis, Support Vector Machine (SVM), K-Nearest Neighbor, Artificial Neural network, were then …


Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan Sep 2022

Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan

Department of Electrical and Computer Engineering: Faculty Publications

Coronary artery disease (CAD) is one of the major cardiovascular diseases and represents the leading causes of global mortality. Developing new diagnostic and therapeutic approaches for CAD treatment are critically needed, especially for an early accurate CAD detection and further timely intervention. In this study, we successfully isolated human plasma small extracellular vesicles (sEVs) from four stages of CAD patients, that is, healthy control, stable plaque, non-ST-elevation myocardial infarction, and ST-elevation myocardial infarction. Surface-enhanced Raman scattering (SERS) measurement in conjunction with five machine learning approaches, including Quadratic Discriminant Analysis, Support Vector Machine (SVM), K-Nearest Neighbor, Artificial Neural network, were then …


Nonlinear Strong Coupling By Second-Harmonic Generation Enhancement In Plasmonic Nanopatch Antennas, Bryson Krause, Dhananjay Mishra, Jiyang Chen, Christos Argyropoulos, Thang Hoang Aug 2022

Nonlinear Strong Coupling By Second-Harmonic Generation Enhancement In Plasmonic Nanopatch Antennas, Bryson Krause, Dhananjay Mishra, Jiyang Chen, Christos Argyropoulos, Thang Hoang

Department of Electrical and Computer Engineering: Faculty Publications

Enhanced electromagnetic fields within plasmonic nanocavity mode volumes enable multiple significant effects that lead to applications in both the linear and nonlinear optical regimes. In this work, we demonstrate enhanced second harmonic generation from individual plasmonic nanopatch antennas which are formed by separating silver nanocubes from a smooth gold film using a sub-10 nm zinc oxide spacer layer. When the nanopatch antennas are excited at their fundamental plasmon frequency, a 104-fold increase in the intensity of the second harmonic generation wave is observed. Moreover, by integrating quantum emitters that have an absorption energy at the fundamental frequency, a …


A New Implementation Of Federated Learning For Privacy And Security Enhancement, Xiang Ma, Haijian Sun, Rose Qingyang Hu, Yi Qian Aug 2022

A New Implementation Of Federated Learning For Privacy And Security Enhancement, Xiang Ma, Haijian Sun, Rose Qingyang Hu, Yi Qian

Department of Electrical and Computer Engineering: Faculty Publications

Motivated by the ever-increasing concerns on personal data privacy and the rapidly growing data volume at local clients, federated learning (FL) has emerged as a new machine learning setting. An FL system is comprised of a central parameter server and multiple local clients. It keeps data at local clients and learns a centralized model by sharing the model parameters learned locally. No local data needs to be shared, and privacy can be well protected. Nevertheless, since it is the model instead of the raw data that is shared, the system can be exposed to the poisoning model attacks launched by …


Influence Of Aluminum Addition On The Laser Powder Bed Fusion Of Copper-Aluminum Mixtures, Nada Kraiem, Loic Constantin, A. Mao, Fei Wang, Bai Cui, Jean-François Silvain, Yongfeng Lu Jul 2022

Influence Of Aluminum Addition On The Laser Powder Bed Fusion Of Copper-Aluminum Mixtures, Nada Kraiem, Loic Constantin, A. Mao, Fei Wang, Bai Cui, Jean-François Silvain, Yongfeng Lu

Department of Electrical and Computer Engineering: Faculty Publications

The high optical reflectivity of copper (Cu) in the near infrared (NIR) domain and its elevated heat dissipation make Cu a challenging metal for laser powder bed fusion (LPBF), even with high energy densities (EDs). In this study, we demonstrated that adding aluminum (Al) powder by as little as 0.75, 1.5, and 3 wt.% substantially enhances Cu processability, leading to denser (up to 98%) and smoother (Ra = 3.3 𝜇m) Cu-Al parts as compared to 95% and 18 𝜇m, respectively, for the parts printed using pure Cu. In addition, this method reduces the ED required by a factor of two …


Asymmetric Control Of Light At The Nanoscale, Christos Argyropoulos Jul 2022

Asymmetric Control Of Light At The Nanoscale, Christos Argyropoulos

Department of Electrical and Computer Engineering: Faculty Publications

Breaking reciprocity at the nanoscale can produce directional formation of images due to the asymmetric nonlinear optical response of subwavelength anisotropic resonators. The self-induced passive non-reciprocity has advantages compared to magnet or time modulation approaches and may impact both classical and quantum photonics.


Halide Perovskites Enable Polaritonic Xy Spin Hamiltonian At Room Temperature, Renjie Tao, Kai Peng, Louis Haeberlé, Quanwei Li, Dafei Jin, Graham R. Fleming, Stéphane Kéna-Cohen, Xiang Zhang, Wei Bao Jun 2022

Halide Perovskites Enable Polaritonic Xy Spin Hamiltonian At Room Temperature, Renjie Tao, Kai Peng, Louis Haeberlé, Quanwei Li, Dafei Jin, Graham R. Fleming, Stéphane Kéna-Cohen, Xiang Zhang, Wei Bao

Department of Electrical and Computer Engineering: Faculty Publications

Exciton polaritons, the part-light and part-matter quasiparticles in semiconductor optical cavities, are promising for exploring Bose–Einstein condensation, non-equilibrium many-body physics and analogue simulation at elevated temperatures. However, a room-temperature polaritonic platform on par with the GaAs quantum wells grown by molecular beam epitaxy at low temperatures remains elusive. The operation of such a platform calls for long-lifetime, strongly interacting excitons in a stringent material system with large yet nanoscale-thin geometry and homogeneous properties. Here, we address this challenge by adopting a method based on the solution synthesis of excitonic halide perovskites grown under nanoconfinement. Such nanoconfinement growth facilitates the synthesis …


Rechargeable Multi-Cell Battery, Wei Qiao, Taesic Kim, Liyan Qu May 2022

Rechargeable Multi-Cell Battery, Wei Qiao, Taesic Kim, Liyan Qu

Department of Electrical and Computer Engineering: Faculty Publications

A method for power management of a multi - cell battery includes identifying a desired power value and voltage value , determining a battery voltage value and a battery current value for a battery , determining a number of battery banks from a plurality of battery banks to use for the battery , where each battery bank includes one or more battery cells ( or battery modules ) , checking availability of each of the one or more battery cells ( or battery modules ) , selecting one or more battery banks from the plurality of battery banks , where …