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Articles 1 - 17 of 17
Full-Text Articles in Engineering
Biocompatible Flavone-Based Fluorogenic Probes For Quick Wash-Free Mitochondria! Imaging In Living Cells, Bin Liu, Mickey Shah, Ge Zhang, Qin Liu, Yi Pang
Biocompatible Flavone-Based Fluorogenic Probes For Quick Wash-Free Mitochondria! Imaging In Living Cells, Bin Liu, Mickey Shah, Ge Zhang, Qin Liu, Yi Pang
Yi Pang
Mitochondria, vital organelles existing in almost all eukaryotic cells, play a crucial role in energy metabolism and apoptosis of aerobic organisms. In this work, we report two new flavone-based fluorescent probes, MC-Mito1 and MC-Mito2, for monitoring mitochondria in living cells. These two probes exhibit remarkably low toxicity, good cell permeability, and high specificity; these probes complement the existing library of mitochondrial imaging agents. The new dyes give nearly no background fluorescence, and their application does not require tedious postwashing after cell staining. The appreciable tolerance of MC-Mito2 encourages a broader range of biological applications for understanding the cell degeneration and …
Biocompatible Flavone-Based Fluorogenic Probes For Quick Wash-Free Mitochondria! Imaging In Living Cells, Bin Liu, Mickey Shah, Ge Zhang, Qin Liu, Yi Pang
Biocompatible Flavone-Based Fluorogenic Probes For Quick Wash-Free Mitochondria! Imaging In Living Cells, Bin Liu, Mickey Shah, Ge Zhang, Qin Liu, Yi Pang
Ge Zhang
Mitochondria, vital organelles existing in almost all eukaryotic cells, play a crucial role in energy metabolism and apoptosis of aerobic organisms. In this work, we report two new flavone-based fluorescent probes, MC-Mito1 and MC-Mito2, for monitoring mitochondria in living cells. These two probes exhibit remarkably low toxicity, good cell permeability, and high specificity; these probes complement the existing library of mitochondrial imaging agents. The new dyes give nearly no background fluorescence, and their application does not require tedious postwashing after cell staining. The appreciable tolerance of MC-Mito2 encourages a broader range of biological applications for understanding the cell degeneration and …
Bioactive Surface Modification Of Metal Oxides Via Catechol-Bearing Modular Peptides: Multivalent-Binding, Surface Retention, And Peptide Bioactivity, Wen Tang, Gina Policastro, Geng Hua, Kai Guo, Chrys Wesdemiotis, Gary Doll, Matthew Becker
Bioactive Surface Modification Of Metal Oxides Via Catechol-Bearing Modular Peptides: Multivalent-Binding, Surface Retention, And Peptide Bioactivity, Wen Tang, Gina Policastro, Geng Hua, Kai Guo, Chrys Wesdemiotis, Gary Doll, Matthew Becker
Gary L. Doll
A series of multivalent dendrons containing a bioactive osteogenic growth peptide (OGP) domain and surface-binding catechol domains were obtained through solid phase synthesis, and their binding affinity to hydroxyapatite, TiO2, ZrO2, CeO2, Fe3O4 and gold was characterized using a quartz crystal microbalance with dissipation (QCM-d). Using the distinct difference in binding affinity of the bioconjugate to the metal oxides, TiO2-coated glass slides were selectively patterned with bioactive peptides. Cell culture studies demonstrated the bioavailability of the OGP and that OGP remained on the surface for at least 2 weeks under in vitro cell culture conditions. Bone sialoprotein (BSP) and osteocalcein …
Stabilization Of Supported Metal Nanoparticles Using An Ultrathin Porous Shell, X. Liang, J. Li, Miao Yu, C. Mcmurray, J. Falconer, A. Weimer
Stabilization Of Supported Metal Nanoparticles Using An Ultrathin Porous Shell, X. Liang, J. Li, Miao Yu, C. Mcmurray, J. Falconer, A. Weimer
Miao Yu
No abstract provided.
H2 Separation Using Defect-Free, Inorganic Composite Membranes, Miao Yu, H. Funke, R. Noble, J. Falconer
H2 Separation Using Defect-Free, Inorganic Composite Membranes, Miao Yu, H. Funke, R. Noble, J. Falconer
Miao Yu
No abstract provided.
Tuning The Underwater Oleophobicity Of Graphene Oxide Coatings Via Uv Irradiation, H. Li, Yi Huang, Y. Mao, W. Xu, Harry Ploehn, Miao Yu
Tuning The Underwater Oleophobicity Of Graphene Oxide Coatings Via Uv Irradiation, H. Li, Yi Huang, Y. Mao, W. Xu, Harry Ploehn, Miao Yu
Miao Yu
Ultraviolet (UV) irradiation was utilized to gradually modify the chemistry and structure of graphene oxide (GO) flakes, as confirmed by XPS and AFM. Ultrathin GO coatings/membranes, made of UV-irradiated flakes, showed tunable underwater oleophobicity. UV-treated, superoleophobic GO membranes exhibited excellent antifouling capability for oil/water separation.
Ultra-Thin Microporous–Mesoporous Metal Oxide Films Prepared By Molecular Layer Deposition (Mld), X. Liang, Miao Yu, J. Li, Y.-B. Jiang, A. Weimer
Ultra-Thin Microporous–Mesoporous Metal Oxide Films Prepared By Molecular Layer Deposition (Mld), X. Liang, Miao Yu, J. Li, Y.-B. Jiang, A. Weimer
Miao Yu
No abstract provided.
Origin Of The Unique Activity Of Pt/Tio2 Catalysts For The Water–Gas Shift Reaction, Salai Ammal, Andreas Heyden
Origin Of The Unique Activity Of Pt/Tio2 Catalysts For The Water–Gas Shift Reaction, Salai Ammal, Andreas Heyden
Salai C. Ammal
No abstract provided.
Theoretical Investigation Of H2 Oxidation On The Sr2Fe1.5Mo0.5O6 (001) Perovskite Surface Under Anodic Solid Oxide Fuel Cell Conditions, S. Suthirakun, Salai Ammal, A. Muñoz-García, G. Xiao, Fanglin Chen, Hans-Conrad Zur Loye, E. Carter, Andreas Heyden
Theoretical Investigation Of H2 Oxidation On The Sr2Fe1.5Mo0.5O6 (001) Perovskite Surface Under Anodic Solid Oxide Fuel Cell Conditions, S. Suthirakun, Salai Ammal, A. Muñoz-García, G. Xiao, Fanglin Chen, Hans-Conrad Zur Loye, E. Carter, Andreas Heyden
Salai C. Ammal
No abstract provided.
Obtaining Mixed Ionic/Electronic Conductivity In Perovskite Oxides In A Reducing Environment: A Computational Prediction For Doped Srtio3, S. Suthirakun, Salai Ammal, G. Xiao, Fanglin Chen, Kevin Huang, Hans-Conrad Zur Loye, Andreas Heyden
Obtaining Mixed Ionic/Electronic Conductivity In Perovskite Oxides In A Reducing Environment: A Computational Prediction For Doped Srtio3, S. Suthirakun, Salai Ammal, G. Xiao, Fanglin Chen, Kevin Huang, Hans-Conrad Zur Loye, Andreas Heyden
Salai C. Ammal
No abstract provided.
L-Shaped Three-Center Two-Electron (C−C−C)+ Bonding Array, N. Yoshikai, Salai Ammal, E. Nakamura
L-Shaped Three-Center Two-Electron (C−C−C)+ Bonding Array, N. Yoshikai, Salai Ammal, E. Nakamura
Salai C. Ammal
No abstract provided.
On The Importance Of Metal–Oxide Interface Sites For The Water–Gas Shift Reaction Over Pt/Ceo2 Catalysts, S. Aranifard, Salai Ammal, Andreas Heyden
On The Importance Of Metal–Oxide Interface Sites For The Water–Gas Shift Reaction Over Pt/Ceo2 Catalysts, S. Aranifard, Salai Ammal, Andreas Heyden
Salai C. Ammal
No abstract provided.
Synergistic Dimetallic Effects In Propargylic Substitution Reaction Catalyzed By Thiolate-Bridged Diruthenium Complex, Salai Ammal, N. Yoshikai, Y. Inada, Y. Nishibayashi, E. Nakamura
Synergistic Dimetallic Effects In Propargylic Substitution Reaction Catalyzed By Thiolate-Bridged Diruthenium Complex, Salai Ammal, N. Yoshikai, Y. Inada, Y. Nishibayashi, E. Nakamura
Salai C. Ammal
No abstract provided.
Combinatorial Computational Chemistry Approach To The Design Of Metal Oxide Electronics Materials, B. Rodion, Salai Ammal, Y. Inaba, Y. Oumi, S. Takami, M. Kubo, A. Miyamoto, M. Kawasaki, M. Yoshimoto, H. Koinuma
Combinatorial Computational Chemistry Approach To The Design Of Metal Oxide Electronics Materials, B. Rodion, Salai Ammal, Y. Inaba, Y. Oumi, S. Takami, M. Kubo, A. Miyamoto, M. Kawasaki, M. Yoshimoto, H. Koinuma
Salai C. Ammal
Combinatorial chemistry has been developed as an experimental method where it is possible to synthesize hundreds of samples all at once and examine their properties. Recently, we introduced the concept of combinatorial approach to computational chemistry for material design and proposed a new method called `a combinatorial computational chemistry'. In this approach, the effects of large number of dopants, substrates, and buffer layers on the structures, electronic states, and properties of metal oxide electronics material is estimated systematically using computer simulations techniques, in order to predict the best dopant, substrate, and buffer layer for each metal oxide electronics materials.
Analytical Models For Atomic Friction, Yalin Dong, Ajay Vadakkepatt, Ashlie Martini
Analytical Models For Atomic Friction, Yalin Dong, Ajay Vadakkepatt, Ashlie Martini
Dr. Yalin Dong
In this methods article, we describe application of Prandtl–Tomlinson models and their extensions to interpret dry atomic-scale friction. The goal is to provide a practical overview of how to use these models to study frictional phenomena. We begin with the fundamental equations and build on them step-by-step—from the simple quasistatic one-spring, one-mass model for predicting transitions between friction regimes to the two-dimensional and multi-atom models for describing the effect of contact area. The intention is to bridge the gap between theoretical analysis, numerical implementation, and predicted physical phenomena. In the process, we provide an introductory manual with example computer programs …
Zwitteration Of Dextran: A Facile Route To Integrate Antifouling, Switchability And Optical Transparency Into Natural Polymers, Bin Cao, Linlin Li, Haiyan Wu, Qiong Tang, Bingbing Sun, He Dong, Jiang Zhe, Gang Cheng
Zwitteration Of Dextran: A Facile Route To Integrate Antifouling, Switchability And Optical Transparency Into Natural Polymers, Bin Cao, Linlin Li, Haiyan Wu, Qiong Tang, Bingbing Sun, He Dong, Jiang Zhe, Gang Cheng
Dr. Jiang Zhe
This communication reports a facile method for zwitteration of dextran with carboxybetaine (CB), which integrates superior antifouling properties, switchability between zwitterionic and cationic forms, as well as enhanced optical transparency into one polysaccharide material. This study provides a new avenue for generating multifunctional zwitterionic CB materials in situ.
Implantable Polymer/Metal Thin Film Structures For The Localized Treatment Of Cancer By Joule Heating, Nima Rahbar, Kwabena Kan-Dapaah, Christian Theriault, Wole Soboyejo
Implantable Polymer/Metal Thin Film Structures For The Localized Treatment Of Cancer By Joule Heating, Nima Rahbar, Kwabena Kan-Dapaah, Christian Theriault, Wole Soboyejo
Nima Rahbar
This paper presents an implantable polymer/metal alloy thin film structure for localized post-operative treatment of breast cancer. A combination of experiments and models is used to study the temperature changes due to Joule heating by patterned metallic thin films embedded in poly-dimethylsiloxane. The heat conduction within the device and the surrounding normal/cancerous breast tissue is modeled with three-dimensional finite element method (FEM). The FEM simulations are used to explore the potential effects of device geometry and Joule heating on the temperature distribution and lesion (thermal dose). The FEM model is validated using a gel model that mimics biological media. The …