Engineering Commons^™

Self-Assembled Nanoantenna Enhance Optical Activity And Transport In Scalable Thin Films And Interfaces, Keith Richard Berry Jr.

Graduate Theses and Dissertations

Continued population growth and the decrease of existing energy platforms demands long-term solutions for development and implementation of scalable plasmonic metamaterials for energy and agricultural applications. Self-assembled nanoantenna into random and ordered arrangements are advanced herein for optical and thermal enhancements in scalable thin film. An analytical approach to estimating the thermal dynamics of random arrangements of nanoantenna resulted in estimates within 30% across a range of geometric parameters, nanoantenna-containing media, and thermal parameters. Multimodal thermal dynamics of polymer thin films containing gold nanoparticles (AuNPs) were observed through the natural log of the dimensionless temperature driving force plotted versus time …

Synthesis, Characterization, And Evaluation Of Metal Complexes With Cancer Selective Anti-Proliferative Effects And Hydrogen Evolution Catalytic Properties., Nicholas Vishnosky

Electronic Theses and Dissertations

Bis-thiosemicarbazones (BTSC) and their metal chelates have properties that are useful in several different scientific fields. These systems have already received attention in major fields of biology and engineering. Hydrogen evolution reaction (HER) catalysts need to be cheap and operate under minimal overpotentials with a long lifetime. The treatment of cancer requires, novel agents that have potent cytotoxic activity against cancer cells while displaying minimal side effects. In this dissertation the modular synthesis of these bis-thiosemicarbazone systems is utilized to regulate the redox chemistry for employment in the desired sector of chemistry. The ligand and metal chelates synthesized were characterized …

Modeling Of Electrochemical Processes At The Magnesium Anode During Struvite Formation, Tobias Dwyer

Chemical Engineering Undergraduate Honors Theses

This study analyzes the current transients observed during the electrochemical formation of struvite from a solution of ammonium phosphate using a pure magnesium and magnesium alloy electrode. Through converting the chronoamperometric data to chronocoulometric data and fitting the data to various models, the driving mechanisms for struvite nucleation were elucidated. While the pure magnesium anode is controlled by only instantaneous nucleation at the electrode, the AZ31 alloy is nucleation controlled at short times and Cottrell diffusion controlled at long times.

Capture And Release Gels For Optimized Storage (Cargos), Theodore S. Kalbfleisch Ii

Electronic Theses and Dissertations

Unassisted, the lifetime of many proteins outside their natural environment is very short. Scientists generally need to extract the sample, often in remote locations, and then transport, isolate, and store such biospecimens relatively far from the point of origin in order to study them. Currently, the most commonly used methods for storage of biospecimens are cryopreservation or refrigeration which, though effective, have their fair share of flaws. Cryopreservation and refrigeration-based storage of biospecimens requires a great deal of space and other resources to be effective. Furthermore, the hardware required for cold storage does not transport well. These factors make such …

Numerical Study Of Spacer Grid Geometry In A 5 X 5 Nuclear Fuel Rod Bundle, Wan Chuan Fan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Reactor fuel rod bundles serve as the primary heat source in light water reactors (LWRs), commonly found in the aforementioned PWR plants. The fuel rod bundles’ structure consists of a collection of fuel rods put into a parallel grid configuration. The bundles also include fuel rod spacers, which hold the fuel rods in place, in accordance with the grid. Repeating structures of the fuel bundles create the meta-structure in the reactor. In other words, the grid configuration repeats until it fills the entire space of the reactor. This results in reactor fuel rods suspended in the working fluid domain, oriented …

Validation Of An External Bioreactor Filtration Loop Prototype For A Tissue Engineering Test Bed, Jonah Martin Melegrito

Theses and Dissertations

As a cell line thrives within a culture, some of the cells undergo the natural process of death. Whether it is due to apoptotic or necrotic causes, cell death is a significant hurdle for tissue engineering and cell cultivation. When cells attached to a scaffold die, they slough off from the scaffold into the bloodstream. If left unchecked, these dead cells and any cellular waste products accumulate and could affect the living cells’ ability to survive. The objective of this thesis was to construct a separation system that can filter away any unwanted suspended solids while allowing nutrients to recycle …

Residence Time Distribution (Rtd) Analysis Of A Bioreactor's External Recirculation Loop For A Tissue Engineering Test Bed, Adrien Hosking

Theses and Dissertations

Currently, in tissue engineering, the focus is on morphing cells into a particular type of tissue by hand, rather than automating the process. Automating cell feeding and waste removal, alone, still requires the removal of cells from their culture to perform imaging and analysis. Without the ability to automate the imaging in a way that does not risk cell death, the advantages of automating the feeding and waste removal are largely lost. By building a fully automated tissue engineering test bed, the capacity for cell reproducibility and cell yield increases significantly. This thesis outlines the design, some initial testing, and …

Recovery Of Water And Salt From Hyper-Saline Mine Water Using Freeze Crystallization, Gabrielle Casey

Chemical Engineering Undergraduate Honors Theses

The Freezerbacks researched, designed, and economically evaluated a full-scale freeze crystallization process as well as two alternative full-scale processes: 5 stage multiple effect evaporation and reverse osmosis. All three processes were designed to treat hyper-saline mine water that was sent into evaporation pond systems. These systems were designed for Freeport-McMoRan’s mines that need to treat impacted water.

The Freeport-McMoRan copper mine in Miami, Arizona was visited in order to gain insight about the problem. The mine is no longer actively mining copper and is in the process of reclaiming land used. An essential part of restoring the land is treating …

Development Of A Ws2 Catalyst For Hydrogen Evolution And Improvement Via Platinum Nanoparticle Decoration, Alexander O'Brien

Chemical Engineering Undergraduate Honors Theses

In response to a growing global need to improve utilization of green energy, the concept of renewable energy storage via electrolytic hydrogen production has gained popularity in recent years. However, the prohibitive expense of the bulk platinum catalysts currently used for the hydrogen evolution reaction prevents such a concept from being widely adoptable. This research focuses on a possible alternative catalyst, nanolayer WS₂, which is capable of promoting the hydrogen evolution reaction while maintaining economic viability. Bulk WS₂ was prepared in semiconducting, nanolayer form through liquid phase exfoliation. Prepared catalyst inks consisting of this material demonstrated successful …

Desalination: Freeze Crystallization, Ibrahim Guiga

Chemical Engineering Undergraduate Honors Theses

The Freezerbacks researched, designed, and economically evaluated a full-scale freeze crystallization process as well as two alternative full-scale processes: 5 stage multiple effect evaporation and reverse osmosis. All three processes were designed to treat hyper-saline mine water that was sent into evaporation pond systems. These systems were designed for Freeport-McMoRan’s mines that need to treat impacted water.

The Freeport-McMoRan copper mine in Miami, Arizona was visited in order to gain insight about the problem. The mine is no longer actively mining copper and is in the process of reclaiming land used. An essential part of restoring the land is treating …

Removal And Reuse Of Phosphorus As A Fertilizer From Cafo Runoff, Hannah Young

Chemical Engineering Undergraduate Honors Theses

Eutrophication is the process in which nutrient saturated waters promote algal blooms on the surface of the water. This limits the amount of dissolved oxygen content in the water, effectively limiting the range of species that can survive in a body of water. Concentrated animal feeding operations (CAFO) can contribute to this issue. The animals in a CAFO produce large amounts of nutrient-rich waste streams that can enter natural waterways if not properly managed and increase the problem of eutrophication. The ability to treat these waste streams and recover the excess nutrients would allow for not only the reduction of …

Effect Of Thiols For Nitrogen Reduction To Ammonia, Zakary R. Ford

Chemical Engineering Undergraduate Honors Theses

Ammonia is an important chemical used for fertilizers and also a potential carbon-free hydrogen storage medium. The Haber-Bosch process is the main production process, which requires large energy- and capital-input. Therefore, it is crucial to develop an alternate scalable synthesis that provides a less energy intensive and more economical route for synthetic ammonia production. In this paper, a 1Fe1Ni film was functionalized with C₃OH and C₆OH for the electrochemical synthesis of ammonia. This work will provide some insight into how thiol ligands can increase the selectivity of the catalyst for nitrogen reduction reaction and can be …

Effects Of Ambient And Laser Light On Water Evaporation From The Surface Of Polyurethane Swabs Doped With Surfactant, Collin Campbell

Chemical Engineering Undergraduate Honors Theses

Polyurethane swabs are a common instrument for environmental sampling in the food, medical, and forensic fields due to their high recovery of organisms like viruses, spores, and bacteria. For sampling microbes in food and medical facilities, storage of the collected samples occurs under the absence of light to promote growth for more accurate testing. In the forensic fields, microbial growth results in sample contamination so the inhibition of this growth requires the drying of the swabs. This work studies the evaporation rates of water from polyurethane swabs under zero watt incident light, 30 W fluorescent bulb, 50 mW 532 nm …

The Synthesis, Purification, And Characterization Of The P3 Peptoid, Myles Joyce

Chemical Engineering Undergraduate Honors Theses

The relatively young field of nano-systems has vast applications over various different fields. Peptoids (peptide analogues) and their uses are consistently investigated components of these nano-studies. A particularly interesting group of peptoids are able to self-assemble into secondary structures under the right conditions. The P3 peptoid is able to form microspheres if properly synthesized and purified. Microspheres are frequently studied due to their low surface area to volume ratios. This unique aspect of microspheres makes them an excellent candidate for drug delivery systems; however, these systems must also be robust so that the desired compound can be encapsulated within the …

Task 1: Silver-Based Microbial Check Valve For Spacecraft Potable Water Systems, Eric Beitle

Chemical Engineering Undergraduate Honors Theses

As human space exploration increases, the development of a more efficient potable water treatment system suited for spacecraft becomes crucial. This Waste-management Education Research Consortium (WERC) challenge was designed to explore the viability of microbial control through the utilization of silver ions as a biocide for possible integration into the Tranquility Node 3 water purification system aboard the International Space Station (ISS). Current systems using iodine risk causing hyperthyroidism from overexposure; however, silver can be safely ingested without this side effect. After researching silver delivery methods including electrochemical ion production, controlled release, or a combination of the two, our team …

Recovery Of Water And Salt From Hyper-Saline Mine Water Using Freeze Crystallization, Clara Somerville

Chemical Engineering Undergraduate Honors Theses

The Freezerbacks researched, designed, and economically evaluated a full-scale freeze crystallization process as well as two alternative full-scale processes: 5 stage multiple effect evaporation and reverse osmosis. All three processes were designed to treat hyper-saline mine water that was sent into evaporation pond systems. These systems were designed for Freeport-McMoRan’s mines that need to treat impacted water.

The Freeport-McMoRan copper mine in Miami, Arizona was visited in order to gain insight about the problem. The mine is no longer actively mining copper and is in the process of reclaiming land used. An essential part of restoring the land is treating …

Removal And Reuse Of Phosphorus As A Fertilizer From Cafo Runoff, Kristin Moore

Chemical Engineering Undergraduate Honors Theses

Eutrophication is the process in which nutrient saturated waters promote algal blooms on the surface of the water. This limits the amount of dissolved oxygen content in the water, effectively limiting the range of species that can survive in a body of water. Concentrated animal feeding operations (CAFO) can contribute to this issue. The animals in a CAFO produce large amounts of nutrient-rich waste streams that can enter natural waterways if not properly managed and increase the problem of eutrophication. The ability to treat these waste streams and recover the excess nutrients would allow for not only the reduction of …

Scale Model And Flow Visualization Of Jack Rabbit Ii Chlorine Field Test, Charlotte Williams

Chemical Engineering Undergraduate Honors Theses

The release of hazardous gases, especially accidental releases, can have a major impact on the surrounding environment and population. The history of accidental hazardous gas releases is filled with plant destruction, civilian injury, and even death. Knowledge of how these gases travel and disperse once released can significantly lessen physical harm and improve emergency procedures. The Jack Rabbit II field test was conducted in pursuit of this knowledge for a chlorine release. In this field test, a purpose-built chlorine tank was surrounded by CONEX trailers assembled in the desert in Utah to model an urban setting. Multiple releases of chlorine …

Recovery Of Water And Salt From Hyper-Saline Mine Water Using Freeze Crystallization, Patsy Ann Dawson

Chemical Engineering Undergraduate Honors Theses

The Freezerbacks researched, designed, and economically evaluated a full-scale freeze crystallization process as well as two alternative full-scale processes: 5 stage multiple effect evaporation and reverse osmosis. All three processes were designed to treat hyper-saline mine water that was sent into evaporation pond systems. These systems were designed for Freeport- McMoRan’s mines that need to treat impacted water.

The Freeport-McMoRan copper mine in Miami, Arizona was visited in order to gain insight about the problem. The mine is no longer actively mining copper and is in the process of reclaiming land used. An essential part of restoring the land is …

Silver-Based Microbial Check Valve For Spacecraft Potable Water Systems, Scott Perry

Chemical Engineering Undergraduate Honors Theses

As human space exploration increases, the development of a more efficient potable water treatment system suited for spacecraft becomes crucial. This Waste-management Education Research Consortium (WERC) challenge was designed to explore the viability of microbial control through the utilization of silver ions as a biocide for possible integration into the Tranquility Node 3 water purification system aboard the International Space Station (ISS). Current systems using iodine risk causing hyperthyroidism from overexposure; however, silver can be safely ingested without this side effect. After researching silver delivery methods including electrochemical ion production, controlled release, or a combination of the two, our team …

Surface Immobilization Of Terpyridine Compounds, Elizabeth Hallett

Chemical Engineering Undergraduate Honors Theses

The deoxydehydration (DODH) of polyols to alkenes is a promising method of producing high-value chemical feedstocks from biomass-derived materials. Current catalytic systems for DODH require the use of costly reducing agents that generate stoichiometric amounts of chemical waste. Immobilizing catalysts on electrode surfaces using chemical linking groups eliminates the need for sacrificial reductants. In this work, glassy carbon electrodes were modified with 4’-(3,4-dihydroxyphenyl)-2,2’:6’,2’’-terpyridine to investigate o-benzoquinone as a potential linking group for DODH, and possibly for other reactions. Previous studies involving electrodes modified with quinone-containing compounds have primarily been focused on catalyzing the oxidation of NADH; the nature or …

Optimization Of Low Salinity Water Flooding In Low Permeability Oil Reservoir, Yang Li

Chemical and Petroleum Engineering Theses

In recent decades, the demand of energy is growing sharply. Oil plays a very important role among all of the energy resources. Low permeability oil reservoirs classified as non conventional oil reservoirs and needs special techniques for oil recovery. The primary aim of this study is to select a proper technique for oil recovery of low permeability carbonate oil reservoir. Different carbonated and non-carbonated brines were employed in this project. Formation brine (17500 ppm), carbonate formation brine, sea water, low salinity water, carbonated sea water (50000 ppm), and carbonated low salinity brine (5000 ppm) were used in this work. Core …

A Review Of Field Oil-Production Response Of Injection-Well Gel Treatments, Munqith Aldhaheri, Mingzhen Wei, Na Zhang, Baojun Bai

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

As life-span extenders, bulk gels have been widely applied to rejuvenate oil production from uneconomic producers in mature oil fields by improving the sweep efficiency of improved-oil-recovery (IOR)/enhanced-oil-recovery (EOR) floods. This paper presents a comprehensive review of the responses of injection-well gel treatments implemented between 1985 and 2014. The survey includes 61 field projects compiled from SPE papers and US Department of Energy reports. Seven parameters related to the oil-production response were evaluated according to the reservoir lithology, formation type, and recovery process, using univariate analysis and stacked histograms. The interquartile-range (IQR) method was used to detect the underperforming and …

Preparation And Electrocatalytic Oxygen Reduction Performance Of Self-Doped Sludge-Derived Carbon, Ya-Li Ye, Wei-Ming Feng, Ge Li, Zhen-Chao Lei, Chun-Hua Feng

Journal of Electrochemistry

The development of low-cost, high-performance cathode catalysts is critical for practical application of fuel cells. Here, the N, P-doped porous graphene-like carbon with outstanding oxygen reduction reaction (ORR) performance was synthesized by pyrolysis of surplus sludge, which functioned as a self-doped, self-activated, and self-templated precursor by acclimation with continuous feedings of phenol. The results show that the amounts of microorganisms were enriched after acclimation, with increasing contents of N, P, Fe, as well as C atoms. The increasing pyrolysis temperature resulted in the formation of an ordered graphitic structure, however, the excessively high temperature induced the drop in the amounts …

Ligand Selectivity In The Recognition Of Protoberberine Alkaloids By Hybrid-2 Human Telomeric G-Quadruplex: Binding Free Energy Calculation, Fluorescence Binding, And Nmr Experiments, Nanjie Deng, Junchao Xia, Lauren Wickstrom, Clement Lin, Kaibo Wang, Peng He, Yunting Yin, Danzhou Yang

Publications and Research

The human telomeric G-quadruplex (G4) is an attractive target for developing anticancer drugs. Natural products protoberberine alkaloids are known to bind human telomeric G4 and inhibit telomerase. Among several structurally similar protoberberine alkaloids, epiberberine (EPI) shows the greatest specificity in recognizing the human telomeric G4 over duplex DNA and other G4s. Recently, NMR study revealed that EPI recognizes specifically the hybrid-2 form human telomeric G4 by inducing large rearrangements in the 50-flanking segment and loop regions to form a highly extensive four-layered binding pocket. Using the NMR structure of the EPI-human telomeric G4 complex, here we perform molecular dynamics free …

Nanogels And Microgels: From Model Colloids To Applications, Recent Developments, And Future Trends, Mattias Karg, Andrij Pich, Thomas Hellweg, Todd Hoare, L. Andrew Lyon, J. J. Crassous, Daisuke Suzuki, Rustam A. Gumerov, Stefanie Schneider, Igor I. Potemkin, Walter Richtering

Engineering Faculty Articles and Research

Nanogels and microgels are soft, deformable, and penetrable objects with an internal gel-like structure that is swollen by the dispersing solvent. Their softness and the potential to respond to external stimuli like temperature, pressure, pH, ionic strength, and different analytes make them interesting as soft model systems in fundamental research as well as for a broad range of applications, in particular in the field of biological applications. Recent tremendous developments in their synthesis open access to systems with complex architectures and compositions allowing for tailoring microgels with specific properties. At the same time state-of-the-art theoretical and simulation approaches offer deeper …

Investigation Of Fouling Mechanisms On Ion Exchange Membranes During Electrolytic Separations, Matthew James Edwards

Honors Theses

The global water crisis is a major problem in our developing world due to the increasing growth of our global population, the depletion of natural water resources, and the continuing contamination of existing water resources as a result of industrialization. Membrane separation is a potential solution for these issues. Electrodialysis (ED) is a separation process which employs membranes to separate inorganic and organic substances. This study investigated how different fouling agents influenced membrane surface characteristic and separation efficiency within an electrodialysis system. While applicable for waste water, this study focuses on model salt water solutions with various fouling agents added …

Metabolon-Inspired Design Of Multi-Modal Catalytic Cascade, Madelaine Seow Chavez

Chemical and Biological Engineering ETDs

Developing hybrid catalytic systems has been researched for the past decade in an effort to efficiently incorporate catalysts of different modalities in catalytic cascades. It has become imperative to design a cascade system where the catalysts are spatially organized to control the delivery of precursors, intermediates, and products. In this work, we have shown that a molecular catalyst, biocatalyst, and metallic catalyst can be co-localized using a carbonaceous support to create a hybrid catalytic system and complete the oxidation of oxalic acid to create a microchemical reactor. The molecular, pyrene-TEMPO catalyst oxidizes glyoxalic acid to oxalic acid. The enzyme oxalate …

Replacement Of A Liquid Filling System For Corrosive Materials, William Breining

Honors Theses

An aging liquid filling system in contact with highly corrosive materials required replacement to protect personnel and surrounding equipment. The current system was investigated to identify areas where efficiency, safety, and productivity could be improved. Several competing solutions, including fillers and bulk chemical storage, were determined along with the corresponding economic and safety studies. The completed study provides information for filler and storage options and provides the necessary legwork for purchase of a replacement system.

Iron-Containing Nanoparticles For The Treatment Of Chrionic Biofilm Infections In Cystic Fibrosis, Leisha M. A. Martin

Nanoscience and Microsystems ETDs

Cystic fibrosis (CF) is the most common genetic disease resulting in the morbidity and mortality of Caucasian children and adults worldwide. Due to a genetic mutation resulting in malfunction of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, CF patients produce highly viscous mucus in their respiratory tract. This leads to impairment of the mucociliary clearance of inhaled microbes. In addition to reduced microbial clearance, anoxic environmental conditions in the lungs promote biofilm-mode growth of the pathogenic bacterial species Pseudomonas aeruginosa. Chronic infections of P. aeruginosa begin in early childhood and typically persist until respiratory failure and death result. The …