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Full-Text Articles in Engineering

Improving The Intellectual And Social Development Of Children With Autism: Design Of A Training Center For Autism, Hasti Jalalian Apr 2021

Improving The Intellectual And Social Development Of Children With Autism: Design Of A Training Center For Autism, Hasti Jalalian

Makara Journal of Technology

Research on the relationship between the role of architecture and the psychology of children with autism, which indicates that appropriate environments for these children can have a significant effect on their healthcare process, has been recently conducted. However, statistics show that autism spectrum disorders are pervasive, and its extent in Iran has been increasing. Moreover, centers that are specifically designed for children with autism are limited, and paradigms are made without considering the mood of these children. Given the role of architecture in designing a suitable space for these children, an investigation that can identify the specific requirements of these …


Numerical Study Of A Buckling Restrained Brace (Brb) In Steel Structures And Comparison With A Convergent Ordinary Brace (Ocb) Under Static And Dynamic Loading, Fatemeh Habibpour Apr 2021

Numerical Study Of A Buckling Restrained Brace (Brb) In Steel Structures And Comparison With A Convergent Ordinary Brace (Ocb) Under Static And Dynamic Loading, Fatemeh Habibpour

Makara Journal of Technology

Bulk metallic glass (BMG) has good mechanical strength, high hardness, wear resistance, and corrosion resistance with promising application in various industries. However, for the industrial production of BMG, the main issue is how to overcome limitations of joining with other materials. The present study focuses on solder processing at low operating temperature to avoid exceeding the recrystallization temperature. A feasible joining process for BMG was developed using lead-free solders. The BMG surface is pre-plated with copper, nickel, or titanium as a wetting layer. The reaction temperature is set between the glass transition temperature of BMG and the melting point of …


Analysis Of The Interfacial Reaction Between Bulk Metallic Glass Coated Copper, Nickel, And Titanium With Lead-Free Solders, Andromeda Dwi Laksono, Yee-Wen Yen, Rifqi Aulia Tanjung, Teodoro A. Amatosa, Ruki Harwahyu Apr 2021

Analysis Of The Interfacial Reaction Between Bulk Metallic Glass Coated Copper, Nickel, And Titanium With Lead-Free Solders, Andromeda Dwi Laksono, Yee-Wen Yen, Rifqi Aulia Tanjung, Teodoro A. Amatosa, Ruki Harwahyu

Makara Journal of Technology

Bulk metallic glass (BMG) has good mechanical strength, high hardness, wear resistance, and corrosion resistance with promising application in various industries. However, for the industrial production of BMG, the main issue is how to overcome limitations of joining with other materials. The present study focuses on solder processing at low operating temperature to avoid exceeding the recrystallization temperature. A feasible joining process for BMG was developed using lead-free solders. The BMG surface is pre-plated with copper, nickel, or titanium as a wetting layer. The reaction temperature is set between the glass transition temperature of BMG and the melting point of …


Design Of Ac Microgrid Topology With Photovoltaic Uncertainties In A Rural Village, Vannak Vai Apr 2021

Design Of Ac Microgrid Topology With Photovoltaic Uncertainties In A Rural Village, Vannak Vai

Makara Journal of Technology

Energy needs are increasing day by day, especially for developing countries, due to population growth and changing lifestyles. A suitable microgrid topology with renewable energy integration is considered to fulfill the people and society’s needs. This paper focuses on the design of AC microgrid topology for a nonelectrified village with the integration of PV uncertainties in both sitting and sizing. The development of an optimal algorithm based on the conductor use minimization and unbalanced load improvement is proposed. The shortest path is proposed to search for the minimum conductor use. Then, the algorithm for improving the unbalanced load with two …


Mean-Shift Object Tracking Algorithm With Systematic Sampling Technique, Yoanes Bandung, Aris Ardiansyah Apr 2021

Mean-Shift Object Tracking Algorithm With Systematic Sampling Technique, Yoanes Bandung, Aris Ardiansyah

Makara Journal of Technology

Mean shift is a fast object tracking algorithm that only considers pixels in an object area, hence its relatively small computational load. This algorithm is suitable for use in real-time conditions in terms of execution time. The use of histograms causes this algorithm to be relatively resistant to rotation and changes in object size. However, its resistance to lighting changes is not optimal. This study aims to improve the performance of the algorithm under lighting changes and reduce its processing time. The proposed technique involves the use of sampling techniques to reduce the number of iterations, optimization of candidate search …


Analysis Of Correlation And Mapping Of Chlorophyll-A Concentrations And Sea Surface Temperatures In Coastal Areas Based On Terra Modis Satellite Image Data, Hendrata Wibisana, Bangun Muljo Sukotjo, Umboro Lasminto Apr 2021

Analysis Of Correlation And Mapping Of Chlorophyll-A Concentrations And Sea Surface Temperatures In Coastal Areas Based On Terra Modis Satellite Image Data, Hendrata Wibisana, Bangun Muljo Sukotjo, Umboro Lasminto

Makara Journal of Technology

Ecosystems in aquatic environments are distinct from ecosystems on land. Changes that occur in ecosystems in aquatic environments affect the lives of biota in these waters, including the fish used as a food source in fishing communities in coastal areas. This study aims to determine the role of remote sensing in mapping and analyzing the relationship between the parameters of sea surface temperature and chlorophyll-a concentrations on the coast. The correlation of sea surface temperature with chlorophyll-a concentrations is modeled via linear regression. An analysis of variance test is performed to establish the suitability of the temperature data for the …


Corrosion Rate Prediction In Frp-Concrete Repair, Mohammad A. Khawaja Apr 2021

Corrosion Rate Prediction In Frp-Concrete Repair, Mohammad A. Khawaja

USF Tampa Graduate Theses and Dissertations

Research has proven that wrapping structural elements with fiber-reinforced polymers (FRPs) slows down chloride-induced corrosion rate but does not stop it. Although FRP has been used for corrosion repair for over 40 years, predictive corrosion rate models for FRP-concrete systems are limited in literature. This dissertation presents an oxygen diffusion-based predictive framework to estimate corrosion rate in FRP-concrete systems.

The dissertation has three main components. First, a core framework that is referred to as Khawaja-Sen-Bhethanabotla (KSB) model. In the KSB model, statistical methods were used to extend experimental data on oxygen permeation coefficients. These data were for one and two …


Discovery And Investigation Of Ammonia Decomposition Catalysts, Katherine Mccullough Apr 2021

Discovery And Investigation Of Ammonia Decomposition Catalysts, Katherine Mccullough

Theses and Dissertations

Liquid ammonia can be used as a hydrogen transportation and generation source for use in PEM fuel cells. Current Ru catalysts for ammonia decomposition contain high loadings of Ru and require reaction temperatures at or above 550°C to attain equilibrium conversion. For on-site hydrogen generation, it is of interest to combine hydrogen generation from ammonia decomposition directly with PEM fuel cells. For this occur, operating temperatures need to be considerably lowered and effluent concentrations of ammonia need to be minimized to avoid poisoning of the membrane. Therefore, it is of interest to develop a low-cost catalyst that exhibits high activity …


Mitigating Corrosion And Enhancing Energy Density Of Zinc-Based Anodes In Primary And Secondary Aqueous Batteries, Ehsan Faegh Apr 2021

Mitigating Corrosion And Enhancing Energy Density Of Zinc-Based Anodes In Primary And Secondary Aqueous Batteries, Ehsan Faegh

Theses and Dissertations

Today Lithium-ion (Li-ion) batteries are the most-emphasized battery technology among the many different battery systems in the market. However, due to their high cost (especially for electric vehicle applications), flammability and toxicity, the development of inexpensive and safer alternative battery chemistries has been the focus of a significant amount of recent research. Among various battery chemistries, Aluminum-based (Al-based) and Zinc-based (Zn-based) batteries have been touted as promising options to compete with Li-ion batteries. However, the practical realization of Al battery chemistries has been difficult over a long period of time (170 years) due to a number of fundamental and intrinsic …


Degradative Processes Of Commercial And Next-Generation Lithium-Ion Battery Materials, Benjamin Ng Apr 2021

Degradative Processes Of Commercial And Next-Generation Lithium-Ion Battery Materials, Benjamin Ng

Theses and Dissertations

The work embodied in this thesis bridges the gap between modern and next-generation Li-ion batteries (LIBs). First, a detailed study of the complex interfacial interactions (e.g. electrode/electrolyte, particle/particle, particle/solid-electrolyte interphase) in existing LIBs (graphite anode, Li(Ni_0.5Mn_0.3Co_0.2)O_2 cathode) are investigated and then used to develop strategies for safer, more energy-dense, and more durable electrode materials (i.e. tailored hybrid materials). The first portion of this thesis focuses heavily on decoupling the complex thermodynamics, reaction kinetics, and mass transport properties in commercially available LIBs. This thesis includes a detailed investigation into the operating parameter space for LIBs, including temperature (-30^oC to +52^oC), state-of-charge …


Developing Eco-Friendly And Cost-Effective Porous Adsorbent For Carbon Dioxide Capture., Mahboubeh Nabavinia, Baishali Kanjilal, Noahiro Fujinuma, Amos Mugweru, Iman Noshadi Mar 2021

Developing Eco-Friendly And Cost-Effective Porous Adsorbent For Carbon Dioxide Capture., Mahboubeh Nabavinia, Baishali Kanjilal, Noahiro Fujinuma, Amos Mugweru, Iman Noshadi

Henry M. Rowan College of Engineering Departmental Research

To address the issue of global warming and climate change issues, recent research efforts have highlighted opportunities for capturing and electrochemically converting carbon dioxide (CO2). Despite metal doped polymers receiving widespread attention in this respect, the structures hitherto reported lack in ease of synthesis with scale up feasibility. In this study, a series of mesoporous metal-doped polymers (MRFs) with tunable metal functionality and hierarchical porosity were successfully synthesized using a one-step copolymerization of resorcinol and formaldehyde with Polyethyleneimine (PEI) under solvothermal conditions. The effect of PEI and metal doping concentrations were observed on physical properties and adsorption results. The results …


Prediction Of Self-Diffusion Constants In Model And Real Systems Using Machine Learning, Joshua P. Allers Mar 2021

Prediction Of Self-Diffusion Constants In Model And Real Systems Using Machine Learning, Joshua P. Allers

Chemical and Biological Engineering ETDs

Understanding diffusion of chemical compounds is important for the design and optimization of many chemical engineering and energy processes. Recent modifications to the Darken equation allow for accurate prediction of Maxwell-Stefan (MS) diffusion in mixtures. Still, there are few practical applications due to the requirement of individual self-diffusion constants. A reliable predictive model for self-diffusion constants would be highly valuable when used in conjunction with the modified Darken equation. Here, we show that Machine Learning (ML) can be used to develop generalized models for self-diffusion in Lennard Jones (LJ) systems and real systems of pure solutions. The use of Artificial …


Adsorption And Transport Of Colloids At Interface And In Bulk, Jingyun Lee Mar 2021

Adsorption And Transport Of Colloids At Interface And In Bulk, Jingyun Lee

LSU Doctoral Dissertations

Colloids are suspensions of microscopic insoluble particles dispersed in a continuum phase such as liquid or gas. Colloids are found in our everyday life from food and cosmetic industries to pharmaceutical and biomedical applications. Depending on a global minimum of the free-energy landscape, colloidal suspensions can be classified as two major classes: equilibrium or active colloidal system. This Ph.D dissertation presents strategies to engineer equilibrium self-assembled structures and out-of-equilibrium active matter using various interparticle forces.

First, we introduce the means to promote the equilibrium self-assembled structures driven by adsorption of colloids at interface. Typically, adsorption of colloids at interface is …


Development Of A New Technology For Obtaining The Substance Of The Drug Acetamizole, Sarvar Saidov, Asqar Abdurazakov, Rixsibay Karimov, Mavluda Baltabayeva Mar 2021

Development Of A New Technology For Obtaining The Substance Of The Drug Acetamizole, Sarvar Saidov, Asqar Abdurazakov, Rixsibay Karimov, Mavluda Baltabayeva

Chemical Technology, Control and Management

The main goal of this work is to obtain a preparation of acetamizole based on local raw materials by a more convenient method of acylation of 2-methoxycarbonylaminobenzimidazole with glacial acetic acid, this synthesis method is proposed for the first time. On the basis of the conducted experiments, favorable conditions for the reaction were found, the influence of the nature of the acid, the temperature, the duration of the reaction and other factors on the course of the reaction was studied, the technology was developed and implemented at the experimental production of "IHRV AN RUz". Based on experiments conducted by scientists …


Methodology For Determination And Assessment Of Uncertainty Sources Of Textile Materials Total Thermal Resistance, Abdurauf Abdurashidovich Abdukayumov, Ortagoli Sharipovich Hakimov Mar 2021

Methodology For Determination And Assessment Of Uncertainty Sources Of Textile Materials Total Thermal Resistance, Abdurauf Abdurashidovich Abdukayumov, Ortagoli Sharipovich Hakimov

Chemical Technology, Control and Management

The problems of improving of methods for determination of the total thermal resistance of textile materials are considered. A comparative analysis of the applied methods based on stationary and non-stationary heat exchange is performed. A higher accuracy of non-stationary methods based on measuring the cooling time of a heat cell with subsequent determination of the cooling rate and the total thermal resistance of the material under study is noted. A method is proposed for estimating the variance of the main values required for calculating the total thermal resistance of materials. The results of the study of the relationship between sources …


Analysis Of Consistency Of Similarity Predicates To Measures Of Similarity And Advantages Of Their Application In Digital Systems For Solving Intellectual Problems, Makhmudjon Abdullaev, Nodira Batirdjanovna Alimova Mar 2021

Analysis Of Consistency Of Similarity Predicates To Measures Of Similarity And Advantages Of Their Application In Digital Systems For Solving Intellectual Problems, Makhmudjon Abdullaev, Nodira Batirdjanovna Alimova

Chemical Technology, Control and Management

The results of the analysis of the correspondence of similarity predicates to similarity measures used in various metric methods used for signal classification and the feasibility of using similarity predicates in the construction of digital systems for solving intellectual problems, for which the simplification of computational operations is of no small importance, are presented. Some general and distinctive features of the similarity predicate are considered in comparison with the euclidean metric in relation to one-dimensional and two-dimensional spaces, and generalized to the case of n-dimensional metric spaces. The expediency of using methods based on the calculation of similarity predicates, which …


Synthesis Of Control Systems For Multidimensional Dynamic Objects Under Parametric Uncertainty Based On The Invariance Theory, U.F Mamirov Mar 2021

Synthesis Of Control Systems For Multidimensional Dynamic Objects Under Parametric Uncertainty Based On The Invariance Theory, U.F Mamirov

Chemical Technology, Control and Management

The problems of synthesis of control systems for multidimensional dynamic objects in the conditions of parametric uncertainty which are based on invariance theory are considered. When constructing stable synthesis algorithms, a recurrent method for determining pseudo-solutions of linear algebraic systems of equations is used. Computational algorithms for the solution based on singular matrix expansions are given. These computational procedures allow us to regularize the problem of synthesis of the considered algorithms for the synthesis of control systems for multidimensional dynamic objects under conditions of parametric uncertainty and improve the quality indicators of control processes.


Calculate The Reliability Of The Bts-Bsc Network With The Reserved Line Connection, Dilmurod Davronbekov, Utkir Karimovich Matyokubov Mar 2021

Calculate The Reliability Of The Bts-Bsc Network With The Reserved Line Connection, Dilmurod Davronbekov, Utkir Karimovich Matyokubov

Chemical Technology, Control and Management

The issue of reserving communication lines between the base station and the mobile network base station controller which are considered as one system is considered. Analytical expressions have been developed for calculating the reliability of the system for various options for backing up communication lines between the base station and the base station controller. The results of research and calculations of reliability for ten different types of backup communication lines of the base station and the base station controller are presented.


Intellectual Educational Technologies Of Coherent Maintenance Of Digital Transformations, Igor Ivanovich Gancherenok, Ulugbek Mannanov, A.G. Davydovsky, Yu.A. Chernyavsky Mar 2021

Intellectual Educational Technologies Of Coherent Maintenance Of Digital Transformations, Igor Ivanovich Gancherenok, Ulugbek Mannanov, A.G. Davydovsky, Yu.A. Chernyavsky

Chemical Technology, Control and Management

The problems of forming adequate educational technologies and supporting digital transformations for the formation and development of relevant professional competencies as innovative receptivity are interpreted. The fundamental principles of educational technologies that act as a catalyst for educational innovations in the context of digital transformation of economic and social processes are described. The main modern educational platforms of educational support of professional activity are analyzed. The author's interpretation of the synergetic effects in the education system, as well as loans as an educational cryptocurrency is suggested.


Mathematical Model Of A System For Controlling And Diagnosing The Safety State Of Oil And Gas Territory, Erkin Uljaev, Utkirjon Murodillaevich Ubaydullaev, Gayrat Bakhtiyarovich Tadzhitdinov, Sherzod Kholmuminovich Eshkuvatov Mar 2021

Mathematical Model Of A System For Controlling And Diagnosing The Safety State Of Oil And Gas Territory, Erkin Uljaev, Utkirjon Murodillaevich Ubaydullaev, Gayrat Bakhtiyarovich Tadzhitdinov, Sherzod Kholmuminovich Eshkuvatov

Chemical Technology, Control and Management

In this article, the way of creation mathematical model of a control system and diagnostics of the security status of the oil and gas territory is considered. For performing diagnostics of the safety of a status of the oil and gas territory as a mathematical apparatus it is suggested to use a boolean algebra. The main controlled objects and their technological parameters which define safety, integrity of saving, operational carrying out monitoring status as separate objects and all oil and gas territory, prediction of the expected threats, economic social, and economic damage are selected. For the creation of a mathematical …


Mathematical Models Of New Magnetoelastic Sensor For Measure Of Power And Vibration Parameters, Javhar Sulton Ugli Fayzullayev Mar 2021

Mathematical Models Of New Magnetoelastic Sensor For Measure Of Power And Vibration Parameters, Javhar Sulton Ugli Fayzullayev

Chemical Technology, Control and Management

In the paper, the mathematical models of the new magnetoelastic sensor for measuring power and vibration parameters are developed taking into account the aggregation or scattering of the parameters of electromagnetic chains and the characteristics of the magnetization curve of the magnetic conductor material. The analysis of the generated mathematical models and graphs based on them showed that the magnetic chain in which the coils are assembled does not take into account the nonlinearity of the magnetization curve of the magnetic conductive material (electrotechnical steel), the result is 12 ÷ 15% of the experimental results. It varies by 6 ÷ …


Study Of The Rheological Properties Of The Suspension Formed During The Production Of Caustic Soda By The Lime Method, Aktam Ulashovich Erkaev, Dildora Tursunova Mar 2021

Study Of The Rheological Properties Of The Suspension Formed During The Production Of Caustic Soda By The Lime Method, Aktam Ulashovich Erkaev, Dildora Tursunova

Chemical Technology, Control and Management

The process of obtaining sodium hydroxide - caustic soda by conversion of soda ash with lime milk in the presence of natural mirabilite - has been investigated. The influence of temperature, Na2CO3: Na2SO4 ratio, concentration of lime milk and duration of the conversion process on this process was studied by identifying their optimal values. The study of the rheological properties of the reaction pulp showed that it is mobile and well filtered, which makes it possible to obtain rapidly settling large crystals of Na2CO3·2Na2SO4, Na …


To Increasing The Absorption Area Of Column Apparatus With Tubular Lattice Nozzles, Nurmukhamedov Habibulla Sagdullaevich, Batir Babatulaev, Elbek Mavlanov, Samukdjan Nigmadjanov Mar 2021

To Increasing The Absorption Area Of Column Apparatus With Tubular Lattice Nozzles, Nurmukhamedov Habibulla Sagdullaevich, Batir Babatulaev, Elbek Mavlanov, Samukdjan Nigmadjanov

Chemical Technology, Control and Management

The problem of creating a compact refrigeration zone for absorbers with tubular-lattice nozzles made of pipes with spiral turbulators is discussed. Research has been carried out on the influence of the groove depth h/D and α/αгл of the step of their placement t/D on the degree of heat transfer intensification α/αо in the transition region of the gas-liquid flow. An intensification of heat transfer has been achieved only by increasing the groove depth from h/D = 0,003 to 0,095 and the optimal pitch of the grooves, the intensity of heat transfer is 2 or more times. Research has …


Estimating The Bubbling Process Of Ozone-Containing Gases In The Water, M.P. Parpiev, А.А. Simonov, Aleksey Kamardin, Abdulaziz M. Nazarov Mar 2021

Estimating The Bubbling Process Of Ozone-Containing Gases In The Water, M.P. Parpiev, А.А. Simonov, Aleksey Kamardin, Abdulaziz M. Nazarov

Chemical Technology, Control and Management

Theoretical estimates were made and significant factors of dissolution of ozone-containing gases in water during bubbling in tanks were determined. The expediency of using microbubbles for more efficient saturation of water and aqueous solutions with ozone and generation of ozone with maximum concentration is shown. It is shown that when bubbling gas in water, including ozone-containing gas, the most important indicator is the volume gas content, which determines the ratio of the volume of the gas phase to the volume of the gas-liquid mixture in the contact apparatus. In the presence of a set of bubbles in the water, the …


Gold-Semiconductor Photocatalysts For Water Treatment Under Visible And Ultraviolet Light, Daniel Willis Mar 2021

Gold-Semiconductor Photocatalysts For Water Treatment Under Visible And Ultraviolet Light, Daniel Willis

LSU Doctoral Dissertations

Water scarcity threatens the lives of millions of people worldwide. It is imperative to improve the energy efficiency and affordability of water treatment methods to avoid a looming water-energy crisis. To meet this challenge, I have pursued research on the use of sunlight—our most reliable and abundant source of energy—to drive water treatment through photocatalysis. I explored the literature and found gold-semiconductor materials to hold promise for harvesting sunlight and catalyzing the breakdown of waterborne contaminants. Initially, I designed a novel optical cavity with gold (Au) nanoparticles on a zinc oxide / titania (TiO2) / aluminum film stack …


Development Of Small-Scale Plutonium Electrorefining In Molten Cacl2, Devin Rappleye, James Mcneese, Richard Torres, Kiel Holliday, Jason R. Jeffries Mar 2021

Development Of Small-Scale Plutonium Electrorefining In Molten Cacl2, Devin Rappleye, James Mcneese, Richard Torres, Kiel Holliday, Jason R. Jeffries

Faculty Publications

Molten salt extraction and electrorefining of plutonium were successfully conducted with only a 200-g initial charge. Due to this small scale, the electrorefining cell components were redesigned relative to conventional, multi-kg standards. The efficiency and yield of this small-scale process are comparable to those of larger-scale exemplars. Chemical analysis of the plutonium product and the anode heel is presented. The product was 99.8% pure. The anode heel was able to be depleted beyond the expected freezing point without significant impurity carryover.


Quantitative Pcr Of Small Nucleic Acids: Size Matters, Jay Min Lim, Rahul Tevatia, Ravi Saraf Mar 2021

Quantitative Pcr Of Small Nucleic Acids: Size Matters, Jay Min Lim, Rahul Tevatia, Ravi Saraf

Department of Chemical and Biomolecular Engineering: Faculty Publications

Quantitative dysregulation in small nucleic acids (NA), such as microRNA (miRNA), extracted from minimally invasive biopsies, such as, blood, stool, urine, nose, throat, are promising biomarker for diseases diagnosis and management. We quantify the effect of the extra step of poly(A) ligation for cDNA synthesis and small size of the NA on the limit of quantification (LOQ) of quantitative PCR (qPCR), the gold standard to measure copy number. It was discovered that for small NA, the cycle threshold, Ct that is proportional to −log[c], where [c] is the concentration of the target NA exhibits a sharp transition. The results indicate …


Fabrication And Characterization Of Electrospun Poly(Acrylonitrile-Co-Methyl Acrylate)/Lignin Nanofibers: Effects Of Lignin Type And Total Polymer Concentration, Suchitha Devadas, Saja M. Nabat Al-Ajrash, Donald A. Klosterman, Kenya A. Crosson, Garry S. Crosson, Erick S. Vasquez Mar 2021

Fabrication And Characterization Of Electrospun Poly(Acrylonitrile-Co-Methyl Acrylate)/Lignin Nanofibers: Effects Of Lignin Type And Total Polymer Concentration, Suchitha Devadas, Saja M. Nabat Al-Ajrash, Donald A. Klosterman, Kenya A. Crosson, Garry S. Crosson, Erick S. Vasquez

Chemical and Materials Engineering Faculty Publications

Lignin macromolecules are potential precursor materials for producing electrospun nanofibers for composite applications. However, little is known about the effect of lignin type and blend ratios with synthetic polymers. This study analyzed blends of poly(acrylonitrile-co-methyl acrylate) (PAN-MA) with two types of commercially available lignin, low sulfonate (LSL) and alkali, kraft lignin (AL), in DMF solvent. The electrospinning and polymer blend solution conditions were optimized to produce thermally stable, smooth lignin-based nanofibers with total polymer content of up to 20 wt % in solution and a 50/50 blend weight ratio. Microscopy studies revealed that AL blends possess good solubility, miscibility, and …


Emulsion Templating Application For Synthesis Of A Porous Zein Biocompatible Oil Adsorbent, Nathan Holley Mar 2021

Emulsion Templating Application For Synthesis Of A Porous Zein Biocompatible Oil Adsorbent, Nathan Holley

LSU Master's Theses

The recovery of spilled oil from water sources using hydrophobic porous absorbent has gained significant interest due to the ease of implementation, large-scale adaptability, and robust nature of the technique. However, the lack of biodegradability of these synthetic adsorbents has caused concern of further contaminating the environment from the generation of microplastic waste that is known to persist and accumulate in the marine food chain and other ecosystems. To mitigate this potential hazard, a new biocompatible alternative is needed to replace the non-degradable synthetic materials currently used. This thesis presents ZEin-based Low Density porous Absorbent (ZELDA), synthesized using a particle …


Polymeric Nanovectors Incorporated With Ganciclovir And Hsv-Tk Encoding Plasmid For Gene-Directed Enzyme Prodrug Therapy, Alicia J. Sawdon, Jun Zhang, Sarah Peng, Esmael M. Alyami, Ching An Peng Mar 2021

Polymeric Nanovectors Incorporated With Ganciclovir And Hsv-Tk Encoding Plasmid For Gene-Directed Enzyme Prodrug Therapy, Alicia J. Sawdon, Jun Zhang, Sarah Peng, Esmael M. Alyami, Ching An Peng

Michigan Tech Publications, Part 1

In the area of gene-directed enzyme prodrug therapy (GDEPT), using herpes simplex virus thymidine kinase (HSV-tk) paired with prodrug ganciclovir (GCV) for cancer treatment has been extensively studied. It is a process involved with two steps whereby the gene (HSV-tk) is first delivered to malignant cells. Afterward, non-toxic GCV is administered to that site and activated to cytotoxic ganciclovir triphosphate by HSV-tk enzyme expressed exogenously. In this study, we presented a one-step approach that both gene and prodrug were delivered at the same time by incorporating them with polymeric micellar nanovectors. GCV was employed as an initiator in the ring-opening …