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Antimicrobial Resistance In Eskape Pathogens And Its Effect On Modern Medicine And Treatment, Cameran Runge May 2023

Antimicrobial Resistance In Eskape Pathogens And Its Effect On Modern Medicine And Treatment, Cameran Runge

Honors Theses

Abstract

ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella

pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter

spp.) are seeing a growing resistance to multiple classes of antibiotics. Misuse and overuse of antibiotics have played directly into the resistance observed, and the problem is growing exponentially. Antibiotic resistance is partially due to several intrinsic factors limiting the drug's uptake. These include efflux pumps, increased biofilm production, and reduced cell wall permeability in the resistant bacteria. ESKAPE pathogens also acquire resistance through horizontal gene transfer and plasmids. As antibiotics have become less effective, the bacteria can continue to thrive, leading to a detrimental …


Setting The Foundation For Experiential Learning And Academic Success In Mbio 101: Introduction To The Microbiology Major, Brandi Sigmon Jan 2021

Setting The Foundation For Experiential Learning And Academic Success In Mbio 101: Introduction To The Microbiology Major, Brandi Sigmon

UNL Faculty Course Portfolios

Introductory courses for majors, typically completed by first-year students, are important to student success and retention as they set the foundation for students in their respective majors. At the University of Nebraska-Lincoln, Microbiology majors complete MBIO 101: Introduction to the Microbiology Major during their first semester as their introductory, foundational course. In this course portfolio, I chose to focus on investigating the impact on student learning of integrating more emphasis on experiential learning knowledge and acquisition within the course through the participation of students in a hands-on workshop and research symposium. Integration of these two events into the MBIO 101 …


Plpt 496/892: Disease Dynamics & Evolution—A Peer Review Of Teaching Project Benchmark Portfolio, Sydney E. Everhart Jan 2016

Plpt 496/892: Disease Dynamics & Evolution—A Peer Review Of Teaching Project Benchmark Portfolio, Sydney E. Everhart

UNL Faculty Course Portfolios

This benchmark course portfolio was developed as a component of the University of Nebraska Peer Review of Teaching. The course selected for this portfolio was a new course developed and taught as an Independent Study PLPT 496/892. The working title for the course was Disease Dynamics and Evolution. This course was designed to cover core concepts of disease ecology and pathogen emergence/evolution. Concepts were organism-agnostic and important for understanding infectious diseases of humans, animals, and plants. The course format was lecture-based and inquiry driven, using primary literature as case studies. The goal of this course was to use interesting and …