Health and Physical Education Commons^™

The Interdependent Roles Of The Psychosocial Predictors Of Human Papillomavirus Vaccination Among Christian Parents Of Unvaccinated Adolescents, Ayokunle Olagoke, Rachel Caskey, Brenikki Floyd, Jennifer Herbert-Beirne, Andrew D. Boyd, Yamilé Molina

Health and Kinesiology Faculty Publications

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Despite the availability of the human papillomavirus (HPV) vaccine, uptake has been sub-optimal among certain religious groups. Psychosocial factors (threat appraisal, coping appraisal, and attitudes) have been identified as independent determinants of HPV vaccination. However, their interdependent effects have not been tested. We examined the interdependency of these psychosocial factors in predicting HPV vaccination intention among Christian parents of unvaccinated adolescents (using a theory-driven conceptual model). A cross-sectional study of 342 participants showed that perceived self-efficacy (β = 0.2, 0.11–0.29, p = <0.0001) and perceived response efficacy of HPV vaccine (β = 0.65, 0.53–0.77. p < .0001) were positively associated with vaccination intention. Our mediation analysis (using the Preachers and Hayes’ approach) shows that attitudes toward HPV vaccination mediated 59% of the relationship between perceived self-efficacy to vaccinate child and HPV …

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Cigarette Smoking After Aerobic Exercise: The Unfavorable Impacts On Vascular Function, Elizabeth J. Pekas, Song-Young Park

Health and Kinesiology Faculty Publications

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It is well-accepted that vascular dysfunction plays a key role in the pathophysiology of cardiovascular diseases. Although vascular dysfunction is multi-faceted, exercise is a commonly recommended prophylactic strategy to preserve vascular function. We and others have shown that exercise training can elicit beneficial effects on vascular function (e.g., blood pressure and conduit artery function) in healthy and clinical populations^1-4. In fact, indices of vascular function are enhanced shortly after acute exercise^5,6, suggesting that the postexercise recovery period may be a crucial component for facilitating long-term vascular adaptations⁷. Poor habits may be …

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Shared Determinants For Human Papillomavirus And Covid-19 Vaccination Intention: An Opportunity For Resource Consolidation, Ayokunle A. Olagoke, Leslie R. Carnahan, Olakanmi Olagoke, Yamile Molina

Health and Kinesiology Faculty Publications

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Purpose

This study aimed at targeting shared factors that influence the prevention of multiple diseases, which can help address various health problems simultaneously. We identified correlates of human papillomavirus (HPV) vaccination that overlap with COVID-19 vaccination.

Design

Cross-sectional survey data.

Setting

Online Qualtrics recruitment panel.

Subject

Religious parents of 342 adolescents who were unvaccinated for HPV (response rate was 68.1%).

Measures

Outcome variables were COVID-19 vaccination intention for (1) self, (2) child, and (3) HPV vaccination intention for child. Independent variables were psychological factors. Covariates were sociodemographic and socioeconomic factors.

Analysis

We conducted multivariate linear regressions on each outcome variable …

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Acute High-Intensity Exercise And Skeletal Muscle Mitochondrial Respiratory Function: Role Of Metabolic Perturbation, Matthew T. Lewis, Gregory M. Blain, Corey R. Hart, Gwenael Layec, Matthew J. Rossman, Song-Young Park, Joel D. Trinity, Jayson R. Gifford, Simranjit K. Sidhu, Joshua C. Weavil, Russell S. Richardson

Health and Kinesiology Faculty Publications

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Recently it was documented that fatiguing, high-intensity exercise resulted in a significant attenuation in maximal skeletal muscle mitochondrial respiratory capacity, potentially due to the intramuscular metabolic perturbation elicited by such intense exercise. With the utilization of intrathecal fentanyl to attenuate afferent feedback from group III/IV muscle afferents, permitting increased muscle activation and greater intramuscular metabolic disturbance, this study aimed to better elucidate the role of metabolic perturbation on mitochondrial respiratory function. Eight young, healthy males performed high-intensity cycle exercise in control (CTRL) and fentanyl-treated (FENT) conditions. Liquid chromatography-mass spectrometry and high-resolution respirometry were used to assess metabolites and mitochondrial respiratory …

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Phi-010 - Beating The Bugs: The Role Of Microbiology Tests In Antimicrobial Stewardship In Spinal Cord Injury Units, Harveen Kaur, Ayokunle Olagoke, Ashley M. Hughes

Health and Kinesiology Faculty Publications

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Background: Antimicrobial Stewardship Programs (ASPs) aim to optimize the prescription of antibiotics to combat antimicrobial resistance (AMR), reduce Clostridioides difficile infections, and lower antibiotic expenditures. Although ASPs are implemented in Veterans Health Administrations (VHAs) in the US, they are not targeted at the Spinal Cord Injury (SCI) population, which, relative to other patient populations, is more vulnerable to AMR. The goals of the study were to (1) assess the effectiveness of microbiology testing as a strategy to combat AMR and (2) assess the potential for collaboration among ASP leaders and SCI prescribers for implementation of ASPs in SCI units in …

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Sympathoinhibition And Vasodilation Contribute To The Acute Hypotensive Response Of The Superoxide Dismutase Mimic, Mntnbuoe-2-Pyp5+, In Hypertensive Animals, Sarah L. Schlichte, Elizabeth J. Pekas, Taylor J. Bruett, Elizabeth A. Kosmacek, Bryan T. Hackfort, Jordan M. Rasmussen, Kaushik P. Patel, Song-Young Park, Rebecca E. Oberley-Deegan, Matthew C. Zimmerman

Health and Kinesiology Faculty Publications

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The pathogenesis of hypertension has been linked to excessive levels of reactive oxygen species (ROS), particularly superoxide (O2•−), in multiple tissues and organ systems. Overexpression of superoxide dismutase (SOD) to scavenge O2•− has been shown to decrease blood pressure in hypertensive animals. We have previously shown that MnTnBuOE-2-PyP5+ (BuOE), a manganese porphyrin SOD mimic currently in clinical trials as a normal tissue protector for cancer patients undergoing radiation therapy, can scavenge O2•− and acutely decrease normotensive blood pressures. Herein, we hypothesized that BuOE decreases hypertensive blood pressures. Using angiotensin II (AngII)-hypertensive mice, we demonstrate that BuOE administered both intraperitoneally and …

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Body Mass-Normalized Moderate Dose Of Dietary Nitrate Intake Improves Endothelial Function And Walking Capacity In Patients With Peripheral Artery Disease, Elizabeth J. Pekas, Tesean Wooden, Santosh K. Yadav, Song-Young Park

Health and Kinesiology Faculty Publications

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Peripheral artery disease (PAD) is characterized by the accumulation of atherosclerotic plaques in the lower extremity conduit arteries, which impairs blood flow and walking capacity. Dietary nitrate has been used to reduce blood pressure (BP) and improve walking capacity in PAD. However, a standardized dose for PAD has not been determined. Therefore, we sought to determine the effects of a body mass-normalized moderate dose of nitrate (0.11 mmol nitrate/kg) as beetroot juice on serum nitrate/nitrite, vascular function, walking capacity, and tissue oxygen utilization capacity in patients with PAD. A total of 11 patients with PAD received either nitrate supplement or …

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Microvascular Dysfunction In Peripheral Artery Disease: Is Heat Therapy A Viable Treatment?, Cody P. Anderson, Elizabeth J. Pekas, Song-Young Park

Health and Kinesiology Faculty Publications

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Peripheral artery disease (PAD) is characterized by the development of atherosclerotic plaques in the lower-body conduit arteries. PAD is commonly accompanied by microvascular disease, which may result in poor wound healing, plantar ulcer development, and subsequent limb amputation. Understanding the mechanisms underlying the development of plantar ulcers is a critical step in the development of adequate treatment options for patients with PAD. Skin is classified into two major components: glabrous and non-glabrous. These skin types have unique microcirculation characteristics, making it important to differentiate between the two when investigating mechanisms for plantar ulcer development in PAD. There is evidence for …

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