Technology and Innovation Commons^™

Cxcl11 And Smica As Predictive Biomarkers For Efficacy Of Anti-Ctla4 Immunotherapy, Keith Sadoon Bahjat, Helena Maria Hoen, Yoshinobu Koguchi, Alan J. Korman

Technology Transfer - Patents

Provided herein are methods for selecting a cancer patient for anti-CTLA-4 immunotherapy, or predicting whether a cancer patient will respond to anti-CTLA4 immunotherapy, based on measured levels of CXCL1 1 and/or sMICA. Such methods are useful for determining whether an anti-CTLA-4 immunotherapy is likely to improve overall survival of a cancer patient. Also provided herein are methods of treating a cancer patient with an anti-CTLA-4 immunotherapy, wherein the patient is first tested for levels of CXCL1 1 and/or sMICA. Also provided are methods for treating a cancer patient with a CXCL1 1 antagonist or sMICA ant agonist alone, or in …

Media Backlog Management Application, Luke Hebert

Student Academic Conference

The goal of this project was to create a desktop GUI (Graphical User Interface) application that would manage a user’s media backlog. To do this, the user provides the amount of time they want to spend watching either a show or movie and fills in other optional criteria, such as genre, director, actors, and more. From there, the app returns recommendations based on the search criteria. The backlog of items is provided by the user via a simple search-by-title functionality. This search queries IMDb, a website dedicated to aggregating information about film, TV series, and other visual media, and returns …

Mindstate: A Capstone Project, Kyle Petronio

Honors Theses

Objectives For four years, I have been trying to release music under the moniker of Rookie Plenty. Aside from a few songs on Bandcamp, my releases have been few and far between. In addition to releasing music on streaming platforms, MindState: A Capstone Project is an experiment in exploring genre fluidity. Many mainstream musical projects released in the twenty-first century are often genre constrained and demonstrate minimal sonic deviation between songs. This extended-play album is an attempt to exemplify a mastery of genre conventions while branching outward into new musical territory.

Methods To demonstrate an understanding of genres, I focused …

Lessons Learned: Alejandro Latorre, Maryann Haggerty

Journal of Financial Crises

At the time of the 2007-09 global financial crisis, Alejandro Latorre was an assistant vice president at the Federal Reserve Bank of New York (FRBNY). He was active in the bailout of American International Group (AIG) from its inception to the end, when AIG repaid its outstanding obligations to both the Federal Reserve and the U.S. Treasury. This Lessons Learned summary is based on a Feb. 26, 2020, interview. He emphasized that the views discussed here are his own, not the views of anyone else currently or previously within the Federal Reserve System or the views of his current employer.

Automation Anxieties: Perceptions About Technological Automation And The Future Of Pharmacy Work, Cameron W. Piercy, Angela N. Gist-Mackey

Human-Machine Communication

This study uses a sample of pharmacists and pharmacy technicians (N = 240) who differ in skill, education, and income to replicate and extend past findings about socioeconomic disparities in the perceptions of automation. Specifically, this study applies the skills-biased technical change hypothesis, an economic theory that low-skill jobs are the most likely to be affected by increased automation (Acemoglu & Restrepo, 2019), to the mental models of pharmacy workers. We formalize the hypothesis that anxiety about automation leads to perceptions that jobs will change in the future and automation will increase. We also posit anxiety about overpayment related to …

The Machine As An Extension Of The Body: When Identity, Immersion And Interactive Design Serve As Both Resource And Limitation For The Disabled, Donna Z. Davis, Shelby Stanovsek

Human-Machine Communication

This research explores how the technological affordances of emerging social virtual environments and VR platforms where individuals from an online disability community are represented in avatar form, correspond to these users’ development of embodied identity, ability, and access to work and social communities. The visual attributes of these avatars, which can realistically reflect the user’s physical self or divert from human form entirely, raise interesting questions regarding the role identity plays in the workplace, be it gender, race, age, weight, or visible disability. Additionally, the technology itself becomes fundamental to identity as the increasing use of artificial intelligence (AI), motion …

Secondary Communication Crisis: Social Media News Information, Christi Mcgahan, John Katsion

Liberty University Research Week

Graduate

LUO Remote

Textual or Investigative

A Systematic Literature Review : Information Technology Capital And Performance, Ilham M, Anis Eliyana, Tri Siwi Agustina

Library Philosophy and Practice (e-journal)

This study aims to conduct a systematic literature review of research in the field of Information Technology Capital and Performance with data from all international research publications. The data obtained in this study amounted to 113 academic documents published from 1994 to 2020 globally. Research has discussed a lot about the causal relationship between information technology capital and company performance, the results of empirical studies vary to some extent with the exception of Information Technology business partnerships which are referred to as Information Technology business and strategic alignment. To that end, strategic alignment has emerged as one of the most …

What Is The Digital City?, Amit Midha, Archan Misra

Perspectives@SMU

Urban metropolises must adapt and evolve to address disruption and sustainability challenges

Decarbonising And Digitalising Shipping, Perlin Chan, Serene Johnson, Aladdy Choo, Lay Lin Tan, Annie Koh

Perspectives@SMU

Targeted regulation and a mindset shift are necessary to transform the maritime industry

A Proposed Theoretical Foundation For The Information Systems Discipline (Version 1. 1), Steven Alter

Business Analytics and Information Systems

“Rethink the theoretical foundations of the IS discipline” is one of the grand challenges for IS research identified in a Delphi study in Business Information Systems Engineering (Becker et al., 2015). This draft addresses that challenge directly through an integrated approach to the operation and evolution of systems. Almost any attempt to articulate a theoretical foundation for IS (a TFIS) would need to cover that topic although other attempts might emphasize other topics and other viewpoints.

The proposed Theoretical Foundation for IS (TFIS) has three main goals:

1) Integration. Build outward from an integrated core. Do not accept the excuse …

Changes In Consumer Market Preference And Purchase Frequency In Response To The Covid-19 Pandemic, Sean Thomas Dial

Masters Theses & Specialist Projects

Research literature throughout 2020 indicate consumer behavioral changes in response to the systemic effects of the global COVID-19 pandemic, but these studies investigate transient adaptations in consumer behaviors during the early quarantine period of the pandemic. This study intends to investigate lasting or permanent changes in consumer market preference and purchase frequency between BAM and online retail due to the effects of the pandemic. The principal investigator designed a survey for participants to estimate purchase frequencies and market preferences for apparel, electronics, groceries, and general purchases before and after the pervasive effects of the pandemic (N = 1195; n = …

Public Safety Agencies And Uav Technology: A Review Of Uses, Lacey L. Weynand

Student Publications

This study utilizes a systematic review of some of the scholarly literature available on drone usage within Southern California, specifically in Los Angeles and Chula Vista. I ask: how do public safety agencies use drone technology? The review will cover cases from existing scholarly literature, as well as policy reports and books from the Google Scholar database. A systematic review was the best methodology to begin fully investigating my research question, since the scope could have been so large that individual data points would have been difficult to find and instead requires a macro-level review. This data will provide a …

Zero Textbook Cost Syllabus For Mgt 4967 (Technology And Innovation In Entrepreneurship), Baruch College Field Center For Entrepreneurship Faculty

Open Educational Resources

This course provides students with a foundation to understand the role, contribution, and potential implications of technology and innovation in any organizational context. The course is relevant for students starting and managing a technology business as well as for students with an interest in taking a strategic approach to the development of technology and innovation in general. The course will provide a mix of theoretical and practical knowledge about the role of technology in entrepreneurship or any form of venture more generally. With a focus on current technologies, the course emphasizes experiential learning, develops students’ understanding of emerging issues, challenges, …

2021 Ijbe V1 Front Matter, Tamra Connor

International Journal for Business Education

1. Editorial Board
2. President's Letter
3. SIEC-ISBE International

Factors Contributing To Innovation Orientation Of Singapore Technology Small And Medium Enterprises (Smes), Kok Beng Neo

Dissertations and Theses Collection (Open Access)

As Singapore transitioned from economy that was primarily dependent on foreign direct investments (FDI) to a knowledge-based economy driven by indigenously developed science, technology and innovations, it became critical for the local firms to grow and internationalize. The government has thus invested heavily (of $19 billion from 2016 to 2020, and $25 billion from 2021 to 2015) in science and technology research and development. The Committee of Future Economy (CFE) concluded that in an era of rapid technological change where innovation cycles have shortened, one of economic strategy is to support our “high growth” enterprises to “scale up”. However, the …

Digital Sustainability And Its Implications For Finance And Climate Change, Gerard George, Simon J.D. Schillebeeckx

Research Collection Lee Kong Chian School Of Business

As the pandemic forced the entire world to a virtual standstill, nature revived a little. The US emitted 10.3% less CO2 in 2020 than in 2019 and other regions similarly experienced emission declines. Depending on the source, global carbon emissions were down between 4 and 8% in 2020.2 Consumers globally have expressed more concern about sustainability, an observation confirmed by large survey research by Accenture, Kantar, Boston Consulting Group (BCG), and Ipsos.3 In its latest Emissions Gap Report4 , the UN Environment Programme (UNEP) explicitly connected the pandemic to climate change, nature loss, and pollution. Besides the acceleration of business …

Knowledge Recombination And Inventor Networks: The Asymmetric Effects Of Embeddedness On Knowledge Reuse And Impact, Simon J.D. Schillebeeckx, Yimin Lin, Gerard George, Tufool Alnuaimi

Research Collection Lee Kong Chian School Of Business

Inventors are triply embedded. They are embedded in a network of knowledge components that they can reuse in future inventions. They are embedded in an inventor network, where internal embeddedness (the strength of relationships between focal inventors and their colleagues upon whose knowledge the team builds) and network centrality influence access to information. Finally, they are embedded in the firm, with its specific routines that favor external or internal knowledge search, what we call search orientation. Using a sample of 39,785 semiconductor patents, we study the pattern of knowledge reuse, or the recombination of technologically similar components, on invention impact. …

Managing Value Co-Creation Effectiveness Within The Healthcare Setting Of The Emirate Of Abu Dhabi: Patients’ Perspectives, Mariam Hamad Al Meraikhi

Dissertations

Value co-creation is an emerging trend in the healthcare context, a topic that is attracting increasing attention in modern healthcare settings as the emphasis shifts to encouraging patient engagement in care delivery. Value co-creation seems appropriate for the healthcare setting because of the intrinsic involvement of patients in activities associated with promoting and protecting their health. However, its application in healthcare is still evolving. This study develops a model of how various actors in healthcare delivery can collaborate to improve the delivery and quality of healthcare services. Deeper insights into how to achieve value co-creation in delivering care have received …

Editorial - Subsistence Marketplaces: Journal, Knowledge-Practice Portal, And Organization, Madhu Viswanathan

Subsistence Marketplaces

Subsistence Marketplaces: Journal, Knowledge-Practice Portal and Organization

2021 School Of Culinary Arts And Food Technology, Spring Newsletter, Tu Dublin., James Murphy

Other resources

The School of Culinary Arts and Food Technology, TU Dublin, Spring Newsletter captured the many events, research, awards, significant contributions and special civic and community activities which the students and staff members of the school have successfully completed up to the Spring period of 2021. The successful completion of these activities would not be possible without the active and on-going support of the 'INSPIRED' friends of Culinary Arts (school supporters) and our school's industry association supporters. In this issue we also fondly remember Cathal Brugha Street, Dublin 2 (as the school now prepares to move to our new campus facilities …

Ion Pairing And Dielectric Decrement In Glycosaminoglycan Brushes, James D. Sterling, Wenjuan Jiang, Wesley M. Botello-Smith, Yun L. Luo

Business and Information Technology Faculty Research & Creative Works

Cell−surface polysaccharides are essential to many aspects of physiology, serving as a highly conserved evolutionary feature of life and as an important part of the innate immune system in mammals. Here, as simplified biophysical models of these sugar coatings, we present results of molecular dynamics simulations of hyaluronic acid and heparin brushes that show important effects of ion pairing, water dielectric decrease, and coion exclusion. As in prior studies of macromolecular crowding under physiologically relevant salt concentrations, our results show equilibria with electroneutrality attained through screening and pairing of brush anionic charges by monovalent cations at the atomistic detail. Most …

From Bus Uncle To Botdistrikt, Abhilash Murthy

Perspectives@SMU

How Abhilash Murthy turned a fun project into a successful chatbot company

Covid-19 Pandemic And Opportunities For Digitalisation Of Smes, Yuanto Kusnadi, Gary Pan

Perspectives@SMU

The Covid-19 pandemic has brought about disruptions in all sectors of economy. With lockdown being implemented in most of the countries around the world, it has necessitated changes in the business models of SMEs. A glaring area of business opportunity focuses on online business. For instance, retailers who do not yet have an online presence or have not been paying much attention to conducting sales online were caught off-guard during the circuit breaker period which has resulted in decreased footfall and plummeting sales in most physical stores. Therefore, having an online retail presence has become critical for businesses, as they …

How Is Fintech Helping Digital Entrepreneurs In Developing Communities?, Carmen Leong

Perspectives@SMU

FinTech is playing an important role in helping digital entrepreneurs tap into growth opportunities in Indonesia's developing communities, according to UNSW Business School research

3d Printing Of Human Microbiome Constituents To Understand Spatial Relationships And Shape Parameters In Bacteriology, Jacques Izard, Teklu Kuru Gerbaba, Shara R. P. Yumul

Department of Food Science and Technology: Faculty Publications

Effective laboratory and classroom demonstration of microbiome size and shape, diversity, and ecological relationships is hampered by a lack of high-resolution, easy-to-use, readily accessible physical or digital models for use in teaching. Three-dimensional (3D) representations are, overall, more effective in communicating visuospatial information, allowing for a better understanding of concepts not directly observable with the unaided eye. Published morphology descriptions and microscopy images were used as the basis for designing 3D digital models, scaled at 20,000×, using computer-aided design software (CAD) and generating printed models of bacteria on mass-market 3D printers. Sixteen models are presented, including rod-shaped, spiral, flask-like, vibroid, …

Digital Exploration Alliances, Anurag Vij

Dissertations and Theses Collection (Open Access)

Digital disruption has impacted every industry and the spending on digital transformation technologies and services worldwide is estimated to reach USD 2.3 trillion by 2023 (Statista, 2021). Reflecting the increasing importance of digital transformation, many firms are entering into strategic alliances that feature traditional industry leaders and digital technology leaders. Little research, however, examines these digital exploration alliances in a systematic way. Accordingly, this dissertation synthesizes extant literature with a theories-in-use approach to conduct depth interviews with 26 managers, with a collective 797 years of experience, to offer a parsimonious definition of digital exploration alliances (DEA) and outlines the similarities …

External Impetus, Co-Production And Grassroots Innovations: The Case Of An Innovation Involving A Language, Wee Liang Tan, Ghil'ad Zuckermann

Research Collection Lee Kong Chian School Of Business

In the field of innovation, three constructs co-exist in different research streams that are exploring disadvantaged communities - grassroots innovations, inclusive innovations and social innovations. In this paper we examine an innovation that involves language: the revival of a language among an Aboriginal tribal community in Australia. In our qualitative-conceptual analysis of the case, we uncover that a) the innovation appears at various stages of the language revival project to cut across the typologies of grassroots, inclusive and social innovations; b) complementarities in the three types of innovation contribute to project initiation, planning, and execution. Based on these findings, we …

Introduction To The Special Issue On “Grassroots And Inclusive Innovations: Conceptualizing Synergies And Complementarities”, Wee Liang Tan, Partha Gangopadhyay, Oscar Hauptman

Research Collection Lee Kong Chian School Of Business

The paper provided a review of the state of the field of grassroots and inclusive innovations, suggested and proposed ways forward for research. It also provided a summary of the articles in the special issue and discussed their contributions. With the extant literature, and the modest contribution of the special issue, the paper postulates that grassroots innovation and inclusive innovation activities are complementary. One the one hand, the inclusive innovations actors and processes facilitate and accelerate grassroots innovation. On the other hand, the knowledge of local context and culture enables effective diffusion of external ideas. The paper also highlights the …

Net-Zero Homes, The Homes Of The Future, Primo Guseppi Facchini

Construction Management

Net-Zero homes are the homes of the future (Holmes, 2018). What makes Net-zero homes unique is they rely on solar power, opposed to all standard housing that relies on the power grid. These homes use solar instead of other forms of energy generating technology because it is more affordable and better for the environment. California has blazed the trail for the rest of the United States and the world to follow with their Net-Zero housing proposition. Starting January 2020 California will require all residential buildings to be net-zero homes. Net-Zero homes are important because it is no secret that our …