Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- American Studies (4280)
- Social and Behavioral Sciences (503)
- Physical Sciences and Mathematics (270)
- Education (240)
- Engineering (221)
-
- Medicine and Health Sciences (198)
- Feminist, Gender, and Sexuality Studies (152)
- Philosophy (131)
- Life Sciences (127)
- History (124)
- Other Education (116)
- Psychology (114)
- History of Art, Architecture, and Archaeology (113)
- Communication (109)
- Women's Studies (89)
- Film and Media Studies (75)
- Public Health (75)
- Teacher Education and Professional Development (75)
- Race, Ethnicity and Post-Colonial Studies (69)
- Civil and Environmental Engineering (65)
- Anthropology (61)
- Rhetoric (61)
- Rhetoric and Composition (61)
- Religion (58)
- Environmental Sciences (53)
- Sociology (51)
- Computer Sciences (50)
- Social and Cultural Anthropology (50)
- Earth Sciences (48)
- Keyword
-
- Gender (90)
- Education (66)
- Race (50)
- Identity (40)
- Feminism (38)
-
- Florida (37)
- Women (37)
- Children (35)
- Ethnography (33)
- Religion (33)
- Depression (32)
- GIS (32)
- Simulation (31)
- Archaeology (28)
- Community (28)
- Performance (28)
- Culture (26)
- Health (26)
- Rhetoric (26)
- Assessment (25)
- Communication (25)
- Ethnicity (25)
- Memory (25)
- Ethics (24)
- Modeling (24)
- Motivation (24)
- Phenomenology (24)
- Architecture (22)
- Development (22)
- Narrative (22)
Articles 1561 - 1590 of 5006
Full-Text Articles in Arts and Humanities
Small Flowerings Of Unhu: The Survival Of Community In Tsitsi Dangarembga's Novels, Dana Rine
Small Flowerings Of Unhu: The Survival Of Community In Tsitsi Dangarembga's Novels, Dana Rine
USF Tampa Graduate Theses and Dissertations
This thesis examines the presence of unhu, a process of becoming and remaining human through community ties, in Tsitsi Dangarembga‟s Nervous Conditions and The Book of Not. Dangarembga interrogates corrupt versions of community by creating positive examples of unhu that alternatively foster community building. Utilizing ecocritical, utopian, and postcolonial methodologies, this thesis postulates that these novels stress the importance of retaining a traditional concept like unhu while also acknowledging the need to adjust it over time to ensure its vitality. Both novels depict the creativity and resilience of unhu amid toxic surroundings.
Apparent Total Evaporative Resistance For Clothing Ensembles At High Heat Stress Levels, Patrick Rodriguez
Apparent Total Evaporative Resistance For Clothing Ensembles At High Heat Stress Levels, Patrick Rodriguez
USF Tampa Graduate Theses and Dissertations
Donning protective clothing for mitigation of hazard from chemical agents poses a problem in the form of heat stress. When choosing protective clothing, many factors must be taken into account including insulative properties and evaporative resistance. This study calculated and compared Re,T,a for three clothing ensembles at levels of heat stress past the level of compensation for heat gain to determine if Re,T,a values varied or remained the same with changes in heat stress level. A three-way mixed model analysis of variance demonstrated significant differences for estimated Re,T,a values among ensembles, heat stress levels and interactions among …
Egyptian Body Size: A Regional And Worldwide Comparison, Michelle H. Raxter
Egyptian Body Size: A Regional And Worldwide Comparison, Michelle H. Raxter
USF Tampa Graduate Theses and Dissertations
Human body size and limb proportions can provide important information about adaptation, population movements, and health disparities. This study investigated changes in body size and limb proportions of adult Egyptians temporally and geographically in relation to climatological, sociopolitical and economic developments. It was predicted that Egyptian groups that experienced more environmental stress would be shorter and exhibit less sexual dimorphism. It was also predicted that Egyptians would be intermediate between higher and lower latitude populations in body form and limb length ratios. The main skeletal sample consisted of 492 males and 528 females, all adults from the Predynastic and Dynastic …
Realizing Virtuality: Tracing The Contours Of Digital Culture, Nicholas Andrew Riggs
Realizing Virtuality: Tracing The Contours Of Digital Culture, Nicholas Andrew Riggs
USF Tampa Graduate Theses and Dissertations
People connect digitally through social media, fusing their relationships with meaning in a non-space of relational potential--a translucent and fluctuating enclave where the self becomes elastic. This thesis explores how I have formed bonds in virtual space through ritual interaction. Looking at the ways I learned to use technology through the progression of a close personal relationship, I suggest that social media use is a performance of identity--a virtuality that exposes how people negotiate the digital enclosure of contemporary society. My story is one of digital nativity and reclaiming love through virtual performance. I show how these performances have had …
Sub-Cooled Pool Boiling Enhancement With Nanofluids, Elliott Charles Rice
Sub-Cooled Pool Boiling Enhancement With Nanofluids, Elliott Charles Rice
USF Tampa Graduate Theses and Dissertations
Phase-change heat transfer is an important process used in many engineering thermal designs. Boiling is an important phase change phenomena as it is a common heat transfer process in many thermal systems. Phase change processes are critical to thermodynamic cycles as most closed loop systems have an evaporator, in which the phase change process occurs. There are many applications/processes in which engineers employ the advantages of boiling heat transfer, as they seek to improve heat transfer performance. Recent research efforts have experimentally shown that nanofluids can have significantly better heat transfer properties than those of the pure base fluids, such …
Characterization Of Aminopeptidase Pepz In Staphylococcus Aureus Virulence, Tiffany Marie Robison
Characterization Of Aminopeptidase Pepz In Staphylococcus Aureus Virulence, Tiffany Marie Robison
USF Tampa Graduate Theses and Dissertations
Staphylococcus aureus is a remarkably successful pathogen, accounting for an estimated 95,000 invasive infections annually in the U.S. alone. The burden of MRSA infections on public healthcare continues to rise, particularly with the continued spread of antibiotic resistant strains and the hyper-virulent CA-MRSA strains. The pathogenic nature of S. aureus can be attributed to the cache of virulence factors encoded within the genome of this organism. Typically, these are secreted toxins which directly interact with the host during infection, and facilitate pathogenesis. A previous screen in our laboratory investigating proteases in S. aureus identified a mutant in aminopeptidase Z as …
Gaming Literacy: Construct Validation And Scale Construction, Kenneth Allen Rosenberg
Gaming Literacy: Construct Validation And Scale Construction, Kenneth Allen Rosenberg
USF Tampa Graduate Theses and Dissertations
This thesis is the first attempt to construct a standardized measure of literacy for the medium of video games, filling a gap in the literature by synthesizing various items of skills, behaviors, and affective components from existent studies and determining their correlations through analyzation of survey data. The five categories that were derived from conceptual review and factor analysis have high measures of internal consistency: Information and Systems Management; Exploration and Enjoyment; Teamwork; Design; and Socialization. To test for external consistency and reliability, the proposed gaming literacy model was compared to the Novak and Hoffman (1997) construction of flow, using …
The Culture Of Mean: Gender, Race, And Class In Mediated Images Of Girls' Bullying, Emily Davis Ryalls
The Culture Of Mean: Gender, Race, And Class In Mediated Images Of Girls' Bullying, Emily Davis Ryalls
USF Tampa Graduate Theses and Dissertations
This dissertation examines narratives about female bullying and aggression through mediated images of "mean girls." Through textual analysis of popular media featuring mean girls (television shows such as Gossip Girl and films like Mean Girls), as well as national news coverage of the case of Phoebe Prince, who reportedly committed suicide after being bullied by girls from her school, this feminist examination questions how the image of the mean girl is raced and classed. This dissertation values an interdisciplinary approach to research that works to make sense of the forces that produce bodies as gendered, raced, and classed.
One of …
Secreted Factors From Human Umbilical Cord Blood Cells Protect Oligodendrocytes From Ischemic Insult, Derrick Rowe
Secreted Factors From Human Umbilical Cord Blood Cells Protect Oligodendrocytes From Ischemic Insult, Derrick Rowe
USF Tampa Graduate Theses and Dissertations
Oligodendrocytes (OL)s are the dominant cell type in the white matter and are integral for synaptic transmission essential for proper neuronal communication between brain areas. Previous studies have shown that intravenous administration of the mononuclear fraction of human umbilical cord blood (HUCB) cells in rat models of stroke reduced white matter injury, gray matter injury and behavioral deficits. Yet the mechanisms used by HUCB cells remain unknown in ischemic injury. These studies will investigate both in vitro and in vivo approaches to elucidate this mechanism in OLs. When mature primary OLs were coincubated with HUCB cells, HUCB cells secreted soluble …
Computational Discovery Of Phenotype Related Biochemical Processes For Engineering, Andrea M. Rocha
Computational Discovery Of Phenotype Related Biochemical Processes For Engineering, Andrea M. Rocha
USF Tampa Graduate Theses and Dissertations
Application of bioengineering technologies for enhanced biological hydrogen production is a promising approach that may play a vital role in sustainable energy. Due to the ability of several naturally occurring microorganisms to generate hydrogen through varying metabolic processes, biological hydrogen has become an attractive alternative energy and fuel source.
One area of particular interest is the production of biological hydrogen in organically-rich engineered systems, such as those associated with waste treatment. Despite the potential for high energy yields, hydrogen yields generated by bacteria in waste systems are often limited due to a focus on microbial utilization of organic material towards …
Visual Search For Smoking Stimuli: Detection And Distraction, Jason A. Oliver
Visual Search For Smoking Stimuli: Detection And Distraction, Jason A. Oliver
USF Tampa Graduate Theses and Dissertations
Extensive research has shown that the attentional systems of addicted individuals are biased towards drug-related stimuli, but despite several decades of effort these results have frequently been inconsistent. Though commonly believed to result from addiction and dependence, cognitive research would suggest that frequent exposure to drug-related stimuli could affect the attentional processing of drug-related cues even if no actual drug use occurs. The present investigation examined attentional bias for smoking cues using a novel visual search paradigm amongst smokers currently in nicotine withdrawal and fully satiated smokers, as well as a non-smoker control group. Variables related to smoking behavior, as …
The Threat To Democracy In Brazil's Public Sphere, Daniel Nettuno
The Threat To Democracy In Brazil's Public Sphere, Daniel Nettuno
USF Tampa Graduate Theses and Dissertations
This thesis looks at the nature of violence with its endemic, and increasingly epidemic presence in Brazil. I analyze the structure of the justice system, police force, and the many governmental security programs in order to better explain why Brazil is so violent and its government has been unable to control this violence. Living under violent conditions, Brazil has become a society where the efficient functioning of the public sphere has been undermined. This public space, shared by citizens, is what many academics believe to be a critical component of a robust and functioning democracy. In Brazil, it is shown, …
Evaluating The Get Into Fitness Today (Gift) Program: Weight Loss And The Roles Of Education And Empowerment, Emily Koby Novicki
Evaluating The Get Into Fitness Today (Gift) Program: Weight Loss And The Roles Of Education And Empowerment, Emily Koby Novicki
USF Tampa Graduate Theses and Dissertations
This study investigated the effects of Get Into Fitness Today (GIFT), a health program for adults that promotes balanced nutrition, physical activity, and weight loss through weekly meetings that provide education and social support. In addition to investigating the effects of GIFT, this evaluation sought to better understand explanatory models used by participants and program staff, and the roles of education and empowerment in weight loss and health education. This mixed methods, case study evaluation consisted of quantitative analysis of existing program records for 664 participants, 40 hours of participant observation of class sessions with ten GIFT groups, and follow-up …
To See And Be Seen: Exploring Layers Of Instructional Leadership And Supervision In The Enactment Of A District-Wide Teacher Evaluation Reform, Jenifer E. Neale
To See And Be Seen: Exploring Layers Of Instructional Leadership And Supervision In The Enactment Of A District-Wide Teacher Evaluation Reform, Jenifer E. Neale
USF Tampa Graduate Theses and Dissertations
This dissertation analyzes instructional leadership and evaluation protocols from a large, diverse district in the Southeastern United States in order to investigate layers of accountability and tensions created when principals are asked to fill the dual roles of both instructional leader and supervisor in a newly implemented teacher evaluation system reform. For this dissertation I investigate the role of the principal as a colleague and mentor and compare this with the role of the principal as supervisor and evaluator in hierarchical systems. I include the role of the peer evaluator, a new position, in my analysis. Critical discourse analysis is …
Nearer, My Farm, To Thee: A Spatial Analysis Of African American Settlement Patterns In Hillsborough County, Florida, Matthew Andrew O'Brien
Nearer, My Farm, To Thee: A Spatial Analysis Of African American Settlement Patterns In Hillsborough County, Florida, Matthew Andrew O'Brien
USF Tampa Graduate Theses and Dissertations
Geographic Information Systems (GIS) have demonstrated their utility in predictively modeling the location of archaeological sites, and providing a framework for cataloging sites eligible for heritage management status. The intent of this GIS-based study is to begin to create a geohistorically organized database of information culled from historic documents and archaeological excavation. In this case study of postbellum land tenure in Hillsborough County, Florida, a GIS-based approach is used to demonstrate the impacts of federal and state land ownership policy decisions during the Reconstruction Era and beyond. GIS data are also used to reveal information about how people use their …
The Effect Of Various Carbohydrate Supplements On Postprandial Blood Glucose Response In Female Soccer Players, Nina Pannoni
The Effect Of Various Carbohydrate Supplements On Postprandial Blood Glucose Response In Female Soccer Players, Nina Pannoni
USF Tampa Graduate Theses and Dissertations
PURPOSE: The purpose of this study is to examine the effects of different types of carbohydrates on blood glucose response in collegiate soccer athletes at rest. This will help to determine the effectiveness of a carbohydrate supplement in providing sustained energy and maintained performance if ingested prior to a soccer match. METHODS: In a cross-over design, 10 female collegiate soccer players (n= 10, age 20.10 ± .99 years, height 65.55 ± 2.77 inches, weight 64.12 ± 8.36 kilograms) from the University of South Florida reported to the laboratory on five separate occasions after an overnight fast. Once a baseline blood …
Multivariate Anti-Inflammatory Approaches To Rescue Neurogenesis And Cognitive Function In Aged Animals, Sandra Antonieta Acosta
Multivariate Anti-Inflammatory Approaches To Rescue Neurogenesis And Cognitive Function In Aged Animals, Sandra Antonieta Acosta
USF Tampa Graduate Theses and Dissertations
Studies have shown that there is a strong correlation between aging and neurodegenerative diseases. Aging is considered the number one risk factor to develop neuropathologies such as memory loss, senile dementia, Alzheimer's disease (AD), and Parkinson's disease. Neurodegenerative diseases tend to start during adulthood, and aggravate over time, making them difficult to prevent and to treat. In the Unites States, demographic studies by U.S. Bureau of the Census have determined that our aging population of >65 years is expected to increase from the present 35 million to 78 million in 2030. This would result, not only to an increase of …
Impact Of A Wellness Clinic Visit On Cardiovascular Risk Biomarkers In Employees Of A Va Medical Center, Margaret Asomaning
Impact Of A Wellness Clinic Visit On Cardiovascular Risk Biomarkers In Employees Of A Va Medical Center, Margaret Asomaning
USF Tampa Graduate Theses and Dissertations
Background: Worksite screening programs are increasingly being provided by employers as a means to reduce cardiovascular risk in employees. A screening program that consists of fasting serum analysis of glucose plus a lipid panel is offered yearly to employees at the VA medical center in Tampa. A retrospective study was conducted to determine if a wellness clinic exposure resulted in significant changes in employees' markers of cardiovascular risk.
Methods: Computerized records were used to follow serial outcomes for glucose, triglycerides, HDL cholesterol, and LDL cholesterol in employees whose screening results showed abnormal levels of one or more of …
Children Who Die Of Abuse: An Examination Of The Effects Of Perpetrator Characteristics On Fatal Versus Non-Fatal Child Abuse, Donald L. Dixon
Children Who Die Of Abuse: An Examination Of The Effects Of Perpetrator Characteristics On Fatal Versus Non-Fatal Child Abuse, Donald L. Dixon
USF Tampa Graduate Theses and Dissertations
Approximately 2000 children die annually in the United States from abuse and neglect, but the interplay of factors such as perpetrator characteristics and family composition which place these children at risk have not been wellestablished. The review of the literature focuses on the correlation between child deaths resulting from abuse and perpetrator characteristics most associated with these deaths. Characteristics such as the perpetrator’s age, race/ethnicity, gender, alcohol and substance use/abuse and/or sale, and prior history of abuse are among those examined. Additionally, these factors are examined within ecological and risk and protective factor theoretical frameworks. It is argued that further …
Making Meaning With "Readers" And "Texts": A Narrative Inquiry Into Two Beginning English Teachers' Meaning Making From Classroom Events, Christi Underwood Edge
Making Meaning With "Readers" And "Texts": A Narrative Inquiry Into Two Beginning English Teachers' Meaning Making From Classroom Events, Christi Underwood Edge
USF Tampa Graduate Theses and Dissertations
Situated in a transactional paradigm, connections between the constructs of meaning and experience in both teacher education and reading in English education guided my construction of a theoretical framework called Classroom Literacy. This framework extends Rosenblatt's Transactional Theory of Reading (1978, 1994, 2005), broadens the concept of text to include the verbal and non-verbal communicative signs related to the context of the classroom, and positions teachers as "readers" of their classrooms as texts. The Classroom Literacy theoretical framework guided my thinking as I re-conceptualized three persistent problems in learning to teach (Hammerness, Darling-Hammond, Bransford, Berliner, Cochran-Smith, McDonald, & Zeichner, 2005)--an …
Literacy And Hazard Communication Comprehension Of Employees Presenting To An Occupational Health Clinic, Christine Bouchard
Literacy And Hazard Communication Comprehension Of Employees Presenting To An Occupational Health Clinic, Christine Bouchard
USF Tampa Graduate Theses and Dissertations
More than 100 million American workers, 7 million workplaces, and 945,000 hazardous chemical products are covered under the Hazard Communication Standard (HCS), regulated by the Occupational Safety and Health Administration. There were a total of 1,183,500 recordable non-fatal illnesses and injuries in private industry workplaces in 2006 resulting in days away from work. Of these, 19,480 were due to chemicals and chemical products. In addition, there were a total of 5,703 work-related fatalities in 2006. In 191 of these, chemicals and chemical products were listed as the primary source of injury and as the secondary source of injury in 104 …
Atomistic Studies Of Shock-Wave And Detonation Phenomena In Energetic Materials, Mikalai Budzevich
Atomistic Studies Of Shock-Wave And Detonation Phenomena In Energetic Materials, Mikalai Budzevich
USF Tampa Graduate Theses and Dissertations
The major goal of this PhD project is to investigate the fundamental properties of energetic materials, including their atomic and electronic structures, as well as mechanical properties, and relate these to the fundamental mechanisms of shock wave and detonation propagation using state-of-the-art simulation methods. The first part of this PhD project was aimed at the investigation of static properties of energetic materials (EMs) with specific focus on 1,3,5-triamino-2,4,6-trinitrobenzene (TATB). The major goal was to calculate the isotropic and anisotropic equations of state for TATB within a range of compressions not accessible to experiment, and to make predictions of anisotropic sensitivity …
A Framework For Determining The Reliability Of Nanoscale Metallic Oxide Semiconductor (Mos) Devices, Wilkistar Otieno
A Framework For Determining The Reliability Of Nanoscale Metallic Oxide Semiconductor (Mos) Devices, Wilkistar Otieno
USF Tampa Graduate Theses and Dissertations
An increase in worldwide investments during the past several decades has pro-pelled scienti c breakthroughs in nanoscience and technology research to new and exciting levels. To ensure that these discoveries lead to commercially viable prod-ucts, it is important to address some of the fundamental engineering and scientific challenges related to nanodevices. Due to the centrality of reliability to product integrity, nanoreliability requires critical analysis and understanding to ensure long-term sustainability of nanodevices and systems. In this study, we construct a relia-bility framework for nanoscale dielectric lms used in Metallic Oxide Semiconductor (MOS) devices. The successful fabrication and incorporation of metallic …
Advanced Signal Processing Techniques For Single Trial Electroencephalography Signal Classification For Brain Computer Interface Applications, Kun Li
USF Tampa Graduate Theses and Dissertations
Brain Computer Interface (BCI) is a direct communication channel between brain and computer. It allows the users to control the environment without the need to control muscle activity [1-2]. P300-Speller is a well known and widely used BCI system that was developed by Farwell and Donchin in 1988 [3]. The accuracy level of the P300-BCI Speller as measured by the percent of communicated characters correctly identified by the system depends on the ability to detect the P300 event related potential (ERP) component among the ongoing electroencephalography (EEG) signal. Different techniques have been tested to reduce the number of trials needed …
Down, But Not Out: An Ethnographic Study Of Women Who Struggled With And Overcame Methamphetamine Addiction, Jodi Nettleton
Down, But Not Out: An Ethnographic Study Of Women Who Struggled With And Overcame Methamphetamine Addiction, Jodi Nettleton
USF Tampa Graduate Theses and Dissertations
Women suffer methamphetamine (meth) addiction at a rate much higher than rates for addiction to other drugs. Female meth users are susceptible and predisposed to gender-related risks: high rates of unprotected vaginal and anal sex, sex-work, and sexual coercion. Precursors for addiction (e.g., abuse, body dysphasia) put females in a difficult position for recovery and highlight the need for gender-specific research and treatment.
Methamphetamine (a synthetically derived stimulant) creates psychological and physical dependency that affects every neuron of the brain and damages the body immediately. Women ingest meth for initial effects that allay social pressures: feeling euphoric, connecting with others …
African American Athletes And The Negotiation Of Public Spaces: An Examination Of Athletic Capital And African American Perceptions Of Success, Keona Lewis
USF Tampa Graduate Theses and Dissertations
This dissertation explores the culture of sport among African American male football players as well as African American perspectives on sport and success. A case study of six African American, Division 1 FBS (Football Bowl Subdivision) collegiate student athletes was conducted along with seventeen supplemental interviews with community members, parents, coaches and former athletes and fans. The participants answered questions that explored education, success, identity construction, ethnicity and sport. Archival data was also reviewed framing the discussion on football in Florida, links between education and sport participation and African American male academic achievement. While many perspectives varied, there were collective …
Corrole Synthesis And Catalytic Applications Toward Cobalt(Iii)-Catalyzed Epoxidation, N-H Insertion, And Cyclopropanation, Chung Sik Kim
Corrole Synthesis And Catalytic Applications Toward Cobalt(Iii)-Catalyzed Epoxidation, N-H Insertion, And Cyclopropanation, Chung Sik Kim
USF Tampa Graduate Theses and Dissertations
A variety of bromocorroles, useful precusors for Pd-based cross coupling, were sucessfully synthesized in moderate to good yields. Chiral corroles were also synthesized through use of chiral amides in the aforementioned cross coupling reactions. Cobalt complexes bearing π-acceptor (CNtBu) and σ-donor (PPh3) ligands were also prepared in excellent yields. In this dissertation, cobalt (III) corrole complexes were applied to three different reaction areas: epoxidation, N-H insertion, and cyclopropanation. Cobalt(III) corroles were found to be efficient catalysts for epoxidation reactions. The epoxidation reactions can be carried out using ethyl phenyldiazoacetate, an acceptor/donor diazo compound, as a carbenoid precusor.The reaction provided highly …
Comparison Of Safety Performance By Design Types At Freeway Diverge Areas And Exit Ramp Sections, Hongyun Chen
Comparison Of Safety Performance By Design Types At Freeway Diverge Areas And Exit Ramp Sections, Hongyun Chen
USF Tampa Graduate Theses and Dissertations
The primary objective of the study is to evaluate the safety performance of different freeway exit types used in current practical designs. More specific, the research objectives include the following two parts: 1) to compare the safety performance of different design types at freeway diverge areas and exit ramp sections; and 2) to identify the impact factors contributing to the crashes happening at these two specific segments.
The study area includes four subjects, the freeway widely-spaced diverge areas; the freeway closely-spaced diverge areas; the left-side off-ramps and the exit ramp sections. For the freeway diverge areas, design types were defined …
Florida's Adolescent Literacy Policy: An Alternative Reading And Response, Diane Kroeger
Florida's Adolescent Literacy Policy: An Alternative Reading And Response, Diane Kroeger
USF Tampa Graduate Theses and Dissertations
In this qualitative case study, I constructed interpretations of the meanings conveyed by state-level discourse communities as they were manifested in the primary and secondary speech genres of Florida’s adolescent literacy policy. Meanings (or values, beliefs and feelings) are highly tacit understandings embedded in the language, actions and objects of policy (Yanow, 2000), and are conveyed through informal and formal speech (Bakhtin, 1986). Results revealed (a) state policy meanings convey multiple versions of literacy with a heavy focus on receptive aspects of literate practice; (b) a typology of students and their fit within the institutional system; and (c) an emphasis …
Evaluation Of Common Inherited Variants In Mitochondrial-Related And Microrna-Related Genes As Novel Risk Factors For Ovarian Cancer, Jennifer Permuth Wey
Evaluation Of Common Inherited Variants In Mitochondrial-Related And Microrna-Related Genes As Novel Risk Factors For Ovarian Cancer, Jennifer Permuth Wey
USF Tampa Graduate Theses and Dissertations
Epithelial ovarian cancer (EOC) is a leading cause of morbidity and mortality among women in the United States, and the etiology is incompletely understood. Common, low penetrant genetic variants such as single nucleotide polymorphisms (SNPs) likely contribute to a significant proportion of EOC. We examined whether SNPs in two understudied yet biologically important types of genes, mitochondrial-related and miRNA-related genes, may contribute to EOC susceptibility using data from a large, homogeneous study population of 1,815 EOC cases and 1,900 controls (frequency-matched on age-group and race/ethnicity) genotyped through stage 1 of an ongoing genome-wide association study. Inter-individual variation in genes involved …