Arts and Humanities Commons^™

The Search For A Coherent Language: The Science And Politics Of Drug Testing And Approval, Jason Karlawish

Jason Karlawish

No abstract provided.

The Importance Of Play In Organisation, Irina M. Verenikina, Helen M. Hasan

I. Verenikina

The role of play as a `social innovation' is attracting emerging research attention since it can affect the emotional climate and complex collaborative performance of the modern workplace. The psychology of play recognises the benefits of incorporating play and `playing games' at work. The increasing use of computer games throughout our society motivates the use of games and game technology for serious purposes including education, training and research. While managers are often reluctant to publicly state that play is good for work, they are willing to use the term `Serious Games'. These are games that engage users in their pursuit, …

Hsisp Annotated Bibliography: Attitudes Toward Animals (1998-2013), Erich Yahner

Erich Yahner, MSLIS

No abstract provided.

Cross-Reactivity And Expansion Of Dengue-Specific T Cells During Acute Primary And Secondary Infections In Humans, Heather L. Friberg-Robertson, Hema Sundara Bashyam, Tomoko Toyosaki-Maeda, James A. Potts, Thomas C. Greenough, Siripen Kalayanarooj, Robert V. Gibbons, Ananda Nisalak, Anon Srikiatkhachorn, Sharone Green, Henry A. F. Stephens, Alan L. Rothman, Anuja Mathew

Alan Rothman

Serotype-cross-reactive memory T cells responding to secondary dengue virus (DENV) infection are thought to contribute to disease. However, epitope-specific T cell responses have not been thoroughly compared between subjects with primary versus secondary DENV infection. We studied CD8(+) T cells specific for the HLA-A*1101-restricted NS3(133) epitope in a cohort of A11(+) DENV-infected patients throughout acute illness and convalescence. We compared the expansion, serotype-cross-reactivity, and activation of these cells in PBMC from patients experiencing primary or secondary infection and mild or severe disease by flow cytometry. Our results show expansion and activation of DENV-specific CD8(+) T cells during acute infection, which …

European Society For The History Of The Human Sciences (Eshhs), Conference 2014, Oulu (Finland), Paper: “Dangerous Passions. The Construction And Cultural And Social Impact Of The ‘Psychiatric’ Framework Of The Passions In France (1790-1830)”, July 22-25 (23th), 2014., Marco Solinas

Marco Solinas

Numerous excellent works have been written on the formation process of ‘psychiatry’ and its concomitant impact on society and culture at the end of the eighteenth century and in the first three decades of the nineteenth century, in particular with regard to France. From Gladys Swain to Dora Weiner, from Jacques Postel to Jan Goldstein, from Jackie Pigeaud to Juan Rigoli, the issue has been analysed in depth and from a variety of different perspectives. However, despite constantly and inevitably resurfacing in these studies, no particular attention has been paid to the passions and emotions drawn up by nascent psychiatry. …

Newcastle And Northumbria Universities, Conference “Fashionable Diseases. Medicine, Literature And Culture, Ca. 1660-1832", Paper: “On The End Of Fashionable Melancholy”, July 3-5 (4th), 2014., Marco Solinas

Marco Solinas

The paper analyze the crucial moment of rupture in the history of the definitions, descriptions and classifications of melancholy within the ambit of medicine that occurred between the end of the Eighteenth- and beginning of the Nineteenth-century, in particular in France. That is the point at which Philippe Pinel, absorbing the contributions of Seventeenth-century British psychiatry, proceeded to abandon both the humoral doctrine and the old Renaissance conception of the dual character – melancholy as a psycho-physiological illness and as a literary and philosophical mood. Pinel now locates melancholy only among forms of mental alienation. I will proceed with the …

Scientists And Animal Research: Dr. Jekyll Or Mr. Hyde?, Andrew N. Rowan

Andrew N. Rowan, DPhil

Why is the public so sensitive about the use of a few tens of millions of animals in research when they do not object to killing hundreds of millions of pigs and cows and billions of chickens for our meat diet? Why is animal research considered so bad despite the public's high opinion of science (and scientists)? Perhaps it is the image of the scientist as an objective and cold individual who deliberately inflicts harm (pain, distress, or death) on his (the public image is usually male) innocent animal victims that arouses so much horror and concern. This paper does …

Graduate School Of Nursing Papers, 1982 – 2010: A Finding Aid, Kristine M. Reinhard

Kristine M. Sjostedt

The Graduate School of Nursing Papers documents the establishment of the Graduate School of Nursing at the University of Massachusetts Medical School, and chronicles its early history and development.

Robert E. Tranquada Papers, 1979-2009: A Finding Aid, Kristine M. Reinhard

Kristine M. Sjostedt

The Robert E. Tranquada Papers chronicle Tranquada’s role as Chancellor and Dean of the University of Massachusetts Medical School.

Memorial Hospital Collection, 1873 – 1990: A Finding Aid, Kristine M. Reinhard

Kristine M. Sjostedt

The Memorial Hospital Collection comprises annual reports and other material by or about The Memorial Hospital in Worcester, Massachusetts.

H. Brownell Wheeler Papers, 1961 – 2009: A Finding Aid, Kristine M. Reinhard

Kristine M. Sjostedt

The H. Brownell Wheeler Papers document the early history of the University of Massachusetts Medical School (UMMS) and University Hospital, collectively known as University of Massachusetts Medical Center (UMMC). This collection also chronicles Dr. Wheeler’s career as a vascular surgeon, educator, administrator, end-of-life care advocate, and inventor. Also included in this collection are materials related to Dr. Wheeler’s personal life including his interest in travel and wood sculpting.

John F. Stockwell Papers, 1966-2006: A Finding Aid, Kristine M. Reinhard

Kristine M. Sjostedt

The John F. Stockwell Papers chronicles Stockwell’s career as the first director of University Hospital, Associate Dean for Administrative Affairs, and Associate Professor of Hospital Administration at the University of Massachusetts Medical School (UMMS). This collection also documents the early history of UMMS and University Hospital, collectively known as University of Massachusetts Medical Center (UMMC).

Samuel Thompson Papers, 1974 – 1982: A Finding Aid, Kristine M. Reinhard

Kristine M. Sjostedt

The Samuel Thompson Papers chronicle the career of Samuel Thompson, Ph.D., Associate Vice Chancellor for Community Relations, Planning and Development and Associate Dean for Administration and Finance at the University of Massachusetts Medical School.

The Death Of Tecumseh, Vivian C. Mcalister

Vivian C. McAlister

In the 1930s, University of Western Ontario surgeon, Dr Edwin Seaborn recorded a series of interviews with members of the Saugeen First Nation to learn about their medical practices. Seaborn used a wax cylinder recording device owned by the medical school. One interview dealt with the death of Shawnee war chief Tecumseh, as told by the grandson of an eye witness to the event. British, Canadian and First Nations' forces retreated eastward up the trail by the Thames River in October 1813. Tecumseh insisted they turn to fight the advancing Americans. The night before the Battle of the Thames, Tecumseh …

A Volunteer Feeding Assistance Program Can Improve Dietary Intakes Of Elderly Patients – A Pilot Study, K. Walton, P. Williams, J. Bracks, Q. Zheng, L. Pond, R. Smoothy, Linda C. Tapsell, M. Batterham, L. Vari

Peter Williams

Malnutrition is prevalent in elderly hospitalised patients and has been associated with longer lengths of stay (LOS), higher rates of complications and increased hospital costs. Feeding assistance has traditionally been the role of nurses, however with an ageing population and an ever-increasing workload there may not be sufficient time to ensure the nutritional care of all patients. A program in which trained volunteers assist, socialise and feed nutritionally vulnerable patients at lunch on weekdays has been initiated in a major suburban hospital in Sydney. The pilot study reported here aimed to evaluate the lunchtime assistance program in terms of dietary …

Validation Of An Australian Electronic Food Frequency Questionnaire To Measure Polyunsaturated Fatty Acid Intake, Monika Swierk, Peter G. Williams, Jennifer Wilcox, Kenneth G. Russell, Barbara J. Meyer

Peter Williams

Objective: To develop and validate a simple non-invasive method that estimates the intakes of omega-3 and omega-6 polyunsaturated fatty acids (PUFA) in a healthy adult population. Methods: A new electronic PUFA food frequency questionnaire (FFQ) was validated by comparison with a 3-d weighed food record and blood biomarkers (erythrocytes and plasma) using the method of triads model and tested for reproducibility. Healthy subjects were recruited from the local Illawarra Region, New South Wales, Australia. Results: The PUFA FFQ adequately estimated intakes for eicosapentaenoic acid, docosahexaenoic acid, total long chain omega-3 PUFA, linoleic acid, total omega-6 PUFA, and total PUFA, which …

Validation Of An Australian Electronic Food Frequency Questionnaire To Measure Polyunsaturated Fatty Acid Intake, Monika Swierk, Peter G. Williams, Jennifer Wilcox, Kenneth G. Russell, Barbara J. Meyer

Peter Williams

Objective: To develop and validate a simple non-invasive method that estimates the intakes of omega-3 and omega-6 polyunsaturated fatty acids (PUFA) in a healthy adult population. Methods: A new electronic PUFA food frequency questionnaire (FFQ) was validated by comparison with a 3-d weighed food record and blood biomarkers (erythrocytes and plasma) using the method of triads model and tested for reproducibility. Healthy subjects were recruited from the local Illawarra Region, New South Wales, Australia. Results: The PUFA FFQ adequately estimated intakes for eicosapentaenoic acid, docosahexaenoic acid, total long chain omega-3 PUFA, linoleic acid, total omega-6 PUFA, and total PUFA, which …

Health Claims And Food Advertising: Comparison Of Marketing And Nutrition Experts' Ratings Of Magazine Advertisements, Sandra C. Jones, Peter Williams, Linda C. Tapsell, Kelly L. Andrews

Peter Williams

To determine the nature and differences in expert opinion from the fields of nutrition and marketing on the use of health claims in the 30 most frequently appearing Australian magazine food advertisements, a survey was conducted with 28 nutritionists and 21 marketing experts in Australia and New Zealand. The experts assessed the advertisements with respect to the accuracy of the nutrition claims, the tactics and intentions of the advertising strategy and the accessibility of the nutrition information to lay consumers. Of 28 advertisements where a claim was identified, for only one did more than 90% believe the claim to be …

Deviance And Diversity In Dietetics, Peter Williams

Peter Williams

Like all professions, dietetics is concerned with the definition, teaching and assessment of professional behaviour (Gingras, 2009; Arnold, 2002), and while diversity may be welcomed, there are limits to what is regarded as acceptable differences in professional practice. There is a dark side: when difference becomes deviance. The deviance of health professionals may seem particularly damaging, because their clients hold them in positions of trust and tend to be unable to question the professional’s judgement (Gauthier, 2001). A dietitian promising to cure cancer with vitamin supplements would be regarded as deviating from the bounds of professionally acceptable behaviour.

Nutrition Status Of Primary Care Patients With Depression And Anxiety, Adrienne K. Forsyth, Peter G. Williams, Frank P. Deane

Peter Williams

The objective of this study was to evaluate the nutrition status of people referred to a nutrition and physical activity program for the management of mental health in a general practice.

Dietary Validation Of A New Australian Food-Frequency Questionnaire That Estimates Long-Chain N-3 Polyunsaturated Fatty Acids, Bethany L. Sullivan, Janelle Brown, Peter Williams, Barbara Meyer

Peter Williams

Currently, there is no FFQ designed to capture the intakes of the long-chain (LC) n-3 PUFA. The objectives of this study were to validate a new LC n-3 PUFA FFQ by comparison with 3 d weighed food records (FR) and to determine its reproducibility assessed 4 to 6 weeks apart. Healthy male and female subjects (n 53) were recruited from Wollongong and the Australian Capital Territory, Australia. The FFQ and FR were analysed for LC n-3 PUFA intakes using a nutrient analysis software package and these intakes were compared using Wilcoxon signed rank tests and Spearman correlation coefficients. Bland–Altman analysis …

Plate Waste In Hospitals And Strategies For Change, Peter G. Williams, Karen Walton

Peter Williams

Plate waste in hospitals refers to the served food that remains uneaten by patients. High levels of plate waste contribute to malnutrition-related complications in hospital, and there are also financial and environmental costs. Plate waste is typically measured by weighing food or by visual estimation of the amount of food remaining on the plate, with results presented as the percentage by weight of the served food, or by calculating the protein, energy or monetary value of the waste. Results from 32 studies in hospitals show a median plate waste of 30% by weight (range: 6-65%), much higher than in other …

Health Benefits Of Herbs And Spices: The Past, The Present, The Future, Linda C. Tapsell, Ian Hemphill, Lynne Cobiac, David R. Sullivan, Michael Fenech, Craig S. Patch, Steven Roodenrys, Jennifer B. Keogh, Peter M. Clifton, Peter G. Williams, Virginia A. Fazio, Karen E. Inge

Peter Williams

The purpose of this supplement is to provide medical and health professionals with a review of the health benefits of herbs and spices. The University of Wollongong, partner organisation of the National Centre of Excellence in Functional Foods, managed the development of the supplement through a committee comprising Professor Linda Tapsell, Dr Craig Patch and Ms Virginia Fazio. Key academics and clinicians with expertise in health and nutrition were invited to review the health aspects of predominantly culinary herbs and spices, using scientific search strategies and National Health and Medical Research Council guidelines for assessing levels of evidence. The resulting …

Food Toxicity And Safety, Peter Williams

Peter Williams

Key Points

• Despite the many potential health risks associated with foods, in practice the degree of risk associated with the modern food supply is extremely low.

• By far the most important hazards of significance are those from biological agents: pathogenic bacteria, viruses, fungi and a few toxic seafoods.

• Trends to larger-scale production, longer distribution chains in the food supply, increased eating away from the home and the emergence of new pathogens means foodborne illness continues to be a significant public health issue.

• The assessment of the safety of food additives is led internationally by JECFA, but …

Simulation In Dietetic Education In Australia, Peter Williams, Eleanor Beck

Peter Williams

In 2011 the Dietitians Association of Australia conducted a survey of simulated learning experiences in all universities offering dietetic course in Australia. A total of 35 SLEs currently used were identified: 14 paper-based, 15 physical-based and 6 computer or video based.

Attitudes Toward Sexuality And Sexual Behaviors Of Asian-American Adolescents: Implications For Risk Of Hiv Infection, Connie S. Chan

Connie Chan

Until 1990, Asian Americans represented an ethnic minority group that was perceived to be at lower risk than African Americans or Hispanics/Latinos for HIV infection, the presumed causal agent for AIDS. Reasons cited for this perception include behavioral differences in intravenous drug use, sexual behavioral habits, and underidentification of AIDS cases. However, in urban areas such as San Francisco, Toronto, New York, Boston, Los Angeles, and Seattle, where Asians have immigrated and settled in large numbers, cases of HIV infection and AIDS have begun to increase dramatically, perhaps reflecting the rise in the number of AIDS cases in Asia. In …

Determinants Of Inapparent And Symptomatic Dengue Infection In A Prospective Study Of Primary School Children In Kamphaeng Phet, Thailand, Timothy P. Endy, Kathryn B. Anderson, Ananda Nisalak, In-Kyu Yoon, Sharone Green, Alan L. Rothman, Stephen J. Thomas, Richard G. Jarman, Daniel H. Libraty, Robert V. Gibbons

Sharone Green

BACKGROUND: Dengue viruses are a major cause of morbidity in tropical and subtropical regions of the world. Inapparent dengue is an important component of the overall burden of dengue infection. It provides a source of infection for mosquito transmission during the course of an epidemic, yet by definition is undetected by health care providers. Previous studies of inapparent or subclinical infection have reported varying ratios of symptomatic to inapparent dengue infection. METHODOLOGY/PRINCIPAL FINDINGS: In a prospective study of school children in Northern Thailand, we describe the spatial and temporal variation of the symptomatic to inapparent (S:I) dengue illness ratio. Our …

T-Cell Responses To Dengue Virus In Humans, Ichiro Kurane, Takaji Matsutani, Ryuji Suzuki, Tomohiko Takasaki, Siripen Kalayanarooj, Sharone Green, Alan L. Rothman, Francis A. Ennis

Sharone Green

Dengue virus (DENV) is a leading cause of morbidity and mortality in most tropical and subtropical areas of the world. Dengue virus infection induces specific CD4+CD8- and CD8+CD4- T cells in humans. In primary infection, T-cell responses to DENV are serotype cross-reactive, but the highest response is to the serotype that caused the infection. The epitopes recognized by DENV-specific T cells are located in most of the structural and non-structural proteins, but NS3 is the protein that is most dominantly recognized. In patients with dengue hemorrhagic fever (DHF) caused by secondary DENV infection, T cells are highly activated in vivo. …

Cross-Reactivity And Expansion Of Dengue-Specific T Cells During Acute Primary And Secondary Infections In Humans, Heather L. Friberg-Robertson, Hema Sundara Bashyam, Tomoko Toyosaki-Maeda, James A. Potts, Thomas C. Greenough, Siripen Kalayanarooj, Robert V. Gibbons, Ananda Nisalak, Anon Srikiatkhachorn, Sharone Green, Henry A. F. Stephens, Alan L. Rothman, Anuja Mathew

Sharone Green

Serotype-cross-reactive memory T cells responding to secondary dengue virus (DENV) infection are thought to contribute to disease. However, epitope-specific T cell responses have not been thoroughly compared between subjects with primary versus secondary DENV infection. We studied CD8(+) T cells specific for the HLA-A*1101-restricted NS3(133) epitope in a cohort of A11(+) DENV-infected patients throughout acute illness and convalescence. We compared the expansion, serotype-cross-reactivity, and activation of these cells in PBMC from patients experiencing primary or secondary infection and mild or severe disease by flow cytometry. Our results show expansion and activation of DENV-specific CD8(+) T cells during acute infection, which …

Tsu Faculty Research Interest Database, David Owerbach

David Owerbach

The TSU faculty research interest database was constructed by the Office of Research and was last updated on November 20, 2014.