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- Osteoarthritis (9)
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- Total hip arthroplasty (4)
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- Autonomic nervous system (2)
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Articles 1 - 30 of 233
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Expansion Of Myeloid-Derived Suppressor Cells Contributes To Metabolic Osteoarthritis Through Subchondral Bone Remodeling, Lixia Zhang, Cameron L. Kirkwood, Jiho Sohn, Ashley Lau, Mary Bayers-Thering, Supinder Kour Bali, Sridhar Rachala, John M. Marzo, Mark J. Anders, Frank Beier, Keith L. Kirkwood
Expansion Of Myeloid-Derived Suppressor Cells Contributes To Metabolic Osteoarthritis Through Subchondral Bone Remodeling, Lixia Zhang, Cameron L. Kirkwood, Jiho Sohn, Ashley Lau, Mary Bayers-Thering, Supinder Kour Bali, Sridhar Rachala, John M. Marzo, Mark J. Anders, Frank Beier, Keith L. Kirkwood
Bone and Joint Institute
Background: Osteoarthritis (OA) subsequent to acute joint injury accounts for a significant proportion of all arthropathies. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of myeloid progenitor cells classically known for potent immune-suppressive activity; however, MDSCs can also differentiate into osteoclasts. In addition, this population is known to be expanded during metabolic disease. The objective of this study was to determine the role of MDSCs in the context of OA pathophysiology. Methods: In this study, we examined the differentiation and functional capacity of MDSCs to become osteoclasts in vitro and in vivo using mouse models of OA and in MDSC …
Diet-Induced Obesity Leads To Behavioral Indicators Of Pain Preceding Structural Joint Damage In Wild-Type Mice, Geoffrey J. Kerr, Bethia To, Ian White, Magali Millecamps, Frank Beier, Matthew W. Grol, Laura S. Stone, Cheryle A. Séguin
Diet-Induced Obesity Leads To Behavioral Indicators Of Pain Preceding Structural Joint Damage In Wild-Type Mice, Geoffrey J. Kerr, Bethia To, Ian White, Magali Millecamps, Frank Beier, Matthew W. Grol, Laura S. Stone, Cheryle A. Séguin
Bone and Joint Institute
Introduction: Obesity is one of the largest modifiable risk factors for the development of musculoskeletal diseases, including intervertebral disc (IVD) degeneration and back pain. Despite the clinical association, no studies have directly assessed whether diet-induced obesity accelerates IVD degeneration, back pain, or investigated the biological mediators underlying this association. In this study, we examine the effects of chronic consumption of a high-fat or high-fat/high-sugar (western) diet on the IVD, knee joint, and pain-associated outcomes. Methods: Male C57BL/6N mice were randomized into one of three diet groups (chow control; high-fat; high-fat, high-sugar western diet) at 10 weeks of age and remained …
Genetic Deletion Of Interleukin-15 Is Not Associated With Major Structural Changes Following Experimental Post-Traumatic Knee Osteoarthritis In Rats, Ermina Hadzic, Garth Blackler, Holly Dupuis, Stephen James Renaud, Christopher Thomas Appleton, Frank Beier
Genetic Deletion Of Interleukin-15 Is Not Associated With Major Structural Changes Following Experimental Post-Traumatic Knee Osteoarthritis In Rats, Ermina Hadzic, Garth Blackler, Holly Dupuis, Stephen James Renaud, Christopher Thomas Appleton, Frank Beier
Bone and Joint Institute
Post-traumatic osteoarthritis (PTOA) is a degenerative joint disease, leading to articular cartilage breakdown, osteophyte formation, and synovitis, caused by an initial joint trauma. Pro-inflammatory cytokines increase catabolic activity and may perpetuate inflammation following joint trauma. Interleukin-15 (IL-15), a pro-inflammatory cytokine, is increased in OA patients, although its roles in PTOA pathophysiology are not well characterized. Here, we utilized Il15 deficient rats to examine the role of IL-15 in PTOA pathogenesis in an injury-induced model. OA was surgically induced in Il15 deficient Holtzman Sprague-Dawley rats and control wild-type rats to compare PTOA progression. Semi-quantitative scoring of the articular cartilage, subchondral bone, …
Total Knee Replacement After High Tibial Osteotomy: Time-To-Event Analysis And Predictors, Codie A. Primeau, Trevor B. Birmingham, Kristyn M. Leitch, Kevin R. Willits, Robert B. Litchfield, Peter J. Fowler, Jacquelyn D. Marsh, Bert M. Chesworth, Stephanie N. Dixon, Dianne M. Bryant, J. Robert Giffin
Total Knee Replacement After High Tibial Osteotomy: Time-To-Event Analysis And Predictors, Codie A. Primeau, Trevor B. Birmingham, Kristyn M. Leitch, Kevin R. Willits, Robert B. Litchfield, Peter J. Fowler, Jacquelyn D. Marsh, Bert M. Chesworth, Stephanie N. Dixon, Dianne M. Bryant, J. Robert Giffin
Bone and Joint Institute
© 2021 Joule Inc. or its licensors. BACKGROUND: An important aim of high tibial osteotomy (HTO) is to prevent or delay the need for total knee replacement (TKR). We sought to estimate the frequency and timing of conversion from HTO to TKR and the factors associated with it. METHODS: We prospectively evaluated patients with osteoarthritis (OA) of the knee who underwent medial opening wedge HTO from 2002 to 2014 and analyzed the cumulative incidence of TKR in July 2019. The presence or absence of TKR on the HTO limb was identified from the orthopedic surgery reports and knee radiographs contained …
Combined Medial Patellofemoral Ligament And Medial Patellotibial Ligament Reconstruction For Recurrent Lateral Patellar Dislocation In Flexion, Taher Abdelrahman, Gilbert Moatshe, Elizabeth Arendt, Julian Feller, Alan Getgood
Combined Medial Patellofemoral Ligament And Medial Patellotibial Ligament Reconstruction For Recurrent Lateral Patellar Dislocation In Flexion, Taher Abdelrahman, Gilbert Moatshe, Elizabeth Arendt, Julian Feller, Alan Getgood
Bone and Joint Institute
© 2020 Arthroscopy Association of North America Recurrent lateral patellar dislocation can be a challenging entity to manage. It results from an imbalance between the restraints to lateralization of the patella and the forces applied to the patella within the biomechanical environment of the knee. The medial patellofemoral ligament has been recognized as the most important static soft-tissue restraint. However, the medial patellotibial ligament and medial patellomeniscal ligament are important for patellar stability at higher degrees of knee flexion. Lateral patellar dislocation in flexion poses a particularly challenging clinical entity with a combination of unique characteristics that need to be …
Barriers, Facilitators, Preferences And Expectations Of Joint Protection Programmes For Patients With Hand Arthritis: A Cross-Sectional Survey, Pavlos Bobos, Joy Macdermid, Christina Ziebart, Eleni Boutsikari, Emily Lalone, Louis Ferreira, Ruby Grewal
Barriers, Facilitators, Preferences And Expectations Of Joint Protection Programmes For Patients With Hand Arthritis: A Cross-Sectional Survey, Pavlos Bobos, Joy Macdermid, Christina Ziebart, Eleni Boutsikari, Emily Lalone, Louis Ferreira, Ruby Grewal
Bone and Joint Institute
© Author(s) (or their employer(s)) 2021. Objectives The objective of this survey was to investigate the barriers, facilitators, expectations and patient preferences regarding joint protection (JP) programmes in people with hand arthritis. Design Cross-sectional survey. Setting Tertiary clinic. Participants Patients with hand arthritis: Osteoarthritis, rheumatoid arthritis, psoriatic arthritis and other forms of arthritis. Primary and secondary outcome measures This study used a survey among people with hand arthritis. Descriptive statistics and percentages were reported for all the data about the barriers, facilitators and preferences around JP. Results A total of 192 patients consented to participate. Most of the patients (82%) …
Quadriceps Tendon Autograft Is Becoming Increasingly Popular In Revision Acl Reconstruction, Philipp W. Winkler, Thiago Vivacqua, Stephan Thomassen, Lisa Lovse, Bryson P. Lesniak, Alan M.J. Getgood, Volker Musahl
Quadriceps Tendon Autograft Is Becoming Increasingly Popular In Revision Acl Reconstruction, Philipp W. Winkler, Thiago Vivacqua, Stephan Thomassen, Lisa Lovse, Bryson P. Lesniak, Alan M.J. Getgood, Volker Musahl
Bone and Joint Institute
© 2021, The Author(s). Purpose: To evaluate trends in revision anterior cruciate ligament reconstruction (ACL-R), with emphasis on intra-articular findings, grafts, and concurrent procedures. It was hypothesized that revision ACL-Rs over time show a trend toward increased complexity with increased use of autografts over allografts. Methods: This was a two-center retrospective study including patients undergoing revision ACL-R between 2010 and 2020. Demographic and surgical data including intra-articular findings and concurrent procedures were collected and compared for the time periods 2010–2014 and 2015–2020. All collected variables were compared between three pre-defined age groups (< 20 years, 20–30 years, > 30 years), right and left knees, and …
Appraisal Of Clinical Practice Guideline: 2018 Update Of The Eular Recommendations For The Management Of Hand Osteoarthritis, Armaghan Dabbagh, Joy C. Macdermid
Appraisal Of Clinical Practice Guideline: 2018 Update Of The Eular Recommendations For The Management Of Hand Osteoarthritis, Armaghan Dabbagh, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Dystrophic Calcification And Heterotopic Ossification In Fibrocartilaginous Tissues Of The Spine In Diffuse Idiopathic Skeletal Hyperostosis (Dish), Dale E. Fournier, Patti K. Kiser, Ryan J. Beach, S. Jeffrey Dixon, Cheryle A. Séguin
Dystrophic Calcification And Heterotopic Ossification In Fibrocartilaginous Tissues Of The Spine In Diffuse Idiopathic Skeletal Hyperostosis (Dish), Dale E. Fournier, Patti K. Kiser, Ryan J. Beach, S. Jeffrey Dixon, Cheryle A. Séguin
Bone and Joint Institute
© 2020, The Author(s). Diffuse idiopathic skeletal hyperostosis (DISH) is a prevalent noninflammatory spondyloarthropathy characterized by ectopic mineral formation along the anterolateral aspect of the vertebral column, yet little is known about its underlying pathogenesis. Our objective was to evaluate the histopathological features and composition of ectopic mineral within spinal tissues affected by DISH in humans. Thoracic spine segments from six embalmed cadaveric donors (one female and five males; median age 82 years) meeting the radiographic diagnostic criteria for DISH were evaluated using radiological, histological, and physical analyses. Overall, the histological features of ectopic mineralization at individual motion segments were …
Reproducibility: Reliability And Agreement Parameters Of The Revised Short Mcgill Pain Questionnaire Version-2 For Use In Patients With Musculoskeletal Shoulder Pain, Samuel U. Jumbo, Joy C. Macdermid, Tara L. Packham, George S. Athwal, Kenneth J. Faber
Reproducibility: Reliability And Agreement Parameters Of The Revised Short Mcgill Pain Questionnaire Version-2 For Use In Patients With Musculoskeletal Shoulder Pain, Samuel U. Jumbo, Joy C. Macdermid, Tara L. Packham, George S. Athwal, Kenneth J. Faber
Bone and Joint Institute
© 2020, The Author(s). Background: The Revised Short McGill Pain Questionnaire Version-2 (SF-MPQ-2) is a multidimensional outcome measure designed to capture, evaluate and discriminate pain from neuropathic and non-neuropathic sources. A recent systematic review found insufficient psychometric data with respect to musculoskeletal (MSK) health conditions. This study aimed to describe the reproducibility (test–retest reliability and agreement) and internal consistency of the SF-MPQ-2 for use among patients with musculoskeletal shoulder pain. Methods: Eligible patients with shoulder pain from MSK sources completed the SF-MPQ-2: at baseline (n = 195), and a subset did so again after 3–7 days (n = 48), if …
Content Validation Of The Kamath And Stothard Questionnaire For Carpal Tunnel Syndrome Diagnosis: A Cognitive Interviewing Study, Armaghan Dabbagh, Joy C. Macdermid, Tara L. Packham, Luciana G. Macedo
Content Validation Of The Kamath And Stothard Questionnaire For Carpal Tunnel Syndrome Diagnosis: A Cognitive Interviewing Study, Armaghan Dabbagh, Joy C. Macdermid, Tara L. Packham, Luciana G. Macedo
Bone and Joint Institute
© 2020, The Author(s). Background: Accurate diagnosis of carpal tunnel syndrome (CTS) is essential for directing appropriate treatment; and for making decisions about work injury claims. The Kamath and Stothard Questionnaire (KSQ) is a self-reported tool used for the diagnosis of CTS. Comprehensibility and comprehensiveness of this questionnaire are critical to diagnostic performance and need to be established. The purpose of the study was to describe how potential respondents, clinicians, and measurement researchers interpret KSQ questions in order to identify and resolve potential sources of misclassification. Methods: Hand therapists, measurement researchers, participants with CTS, and a control group were interviewed …
A Protocol For A Randomized Controlled Trial Investigating The Safety And Cost-Effectiveness Of Outpatient Total Hip Arthroplasty, Bryn O. Zomar, Jacquelyn D. Marsh, Brent A. Lanting, Dianne M. Bryant
A Protocol For A Randomized Controlled Trial Investigating The Safety And Cost-Effectiveness Of Outpatient Total Hip Arthroplasty, Bryn O. Zomar, Jacquelyn D. Marsh, Brent A. Lanting, Dianne M. Bryant
Bone and Joint Institute
© 2020 The Author(s). Background: A significant proportion of the overall cost of total hip arthroplasty (THA) results from the inpatient hospital stay following the procedure. Considering the substantial and increasing number of these procedures performed annually, shifting to an outpatient model of care where the patient is discharged home the same day as their surgery represents a potential for significant cost savings. The potential significant impact of an outpatient care model on constrained healthcare budgets and lack of high-quality evidence regarding its effectiveness warrants a rigorous comparative trial. The purpose of this prospective, randomized controlled trial is to evaluate …
Medical Comorbidities And Functional Dependent Living Are Independent Risk Factors For Short-Term Complications Following Osteotomy Procedures About The Knee, Eric J. Cotter, Anirudh K. Gowd, Daniel D. Bohl, Alan Getgood, Brian J. Cole, Rachel M. Frank
Medical Comorbidities And Functional Dependent Living Are Independent Risk Factors For Short-Term Complications Following Osteotomy Procedures About The Knee, Eric J. Cotter, Anirudh K. Gowd, Daniel D. Bohl, Alan Getgood, Brian J. Cole, Rachel M. Frank
Bone and Joint Institute
© The Author(s) 2018. Objective: To characterize rates and risk factors for adverse events following distal femoral osteotomy (DFO), high tibial osteotomy (HTO), and tibial tubercle osteotomy (TTO) procedures. Design: Patients undergoing DFO, HTO, or TTO procedures during 2005 to 2016 were identified in the American College of Surgeons National Surgical Quality Improvement Program. Rates of adverse events were characterized for each procedure. Demographic, comorbidity, and procedural factors were tested for association with occurrence of any adverse events. Results: A total of 1,083 patients were identified. Of these, 305 (28%) underwent DFO, 273 (25%) underwent HTO, and 505 (47%) underwent …
Appraisal Of Clinical Practice Guideline: Shoulder Pain And Mobility Deficits: Adhesive Capsulitis, Sanaa A. Alsubheen, Joy C. Macdermid
Appraisal Of Clinical Practice Guideline: Shoulder Pain And Mobility Deficits: Adhesive Capsulitis, Sanaa A. Alsubheen, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Correspondence: Reply To Hadidi Et Al, Vanitha Arumugam, Joy C. Macdermid
Correspondence: Reply To Hadidi Et Al, Vanitha Arumugam, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Defining Pain And Interference Recovery Trajectories After Acute Non-Catastrophic Musculoskeletal Trauma Through Growth Mixture Modeling, Joshua Y. Lee, David M. Walton, Paul Tremblay, Curtis May, Wanda Millard, James M. Elliott, Joy C. Macdermid
Defining Pain And Interference Recovery Trajectories After Acute Non-Catastrophic Musculoskeletal Trauma Through Growth Mixture Modeling, Joshua Y. Lee, David M. Walton, Paul Tremblay, Curtis May, Wanda Millard, James M. Elliott, Joy C. Macdermid
Bone and Joint Institute
© 2020 The Author(s). Background: Recovery trajectories support early identification of delayed recovery and can inform personalized management or phenotyping of risk profiles in patients. The objective of this study was to investigate the trajectories in pain severity and functional interference following non-catastrophic musculoskeletal (MSK) trauma in an international, mixed injury sample. Methods: A prospective longitudinal cohort (n = 241) was formed from patients identified within four weeks of trauma, from attendance at emergency or urgent care centres located in London, ON, Canada, or Chicago, IL, USA. Pain interference was measured via the Brief Pain Inventory (London cohort) or the …
Item Reduction Of The Patient-Rated Wrist Evaluation Using Decision Tree Modelling, Mark J.W. Van Der Oest, Jarry T. Porsius, Joy C. Macdermid, Harm P. Slijper, Ruud W. Selles
Item Reduction Of The Patient-Rated Wrist Evaluation Using Decision Tree Modelling, Mark J.W. Van Der Oest, Jarry T. Porsius, Joy C. Macdermid, Harm P. Slijper, Ruud W. Selles
Bone and Joint Institute
© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Background: The aim of this study is to assess the viability of a decision tree version of an often used questionnaire to measure wrist pain and disability, the Patient Rated Wrist Evaluation. Methods: Patient Rated Wrist Evaluation scores were collected from a cohort of 10394 patients who are part of a routine outcome measurement system. A decision tree version of the Patient Rated Wrist Evaluation (PRWE) was created. The intraclass correlation was used to evaluate the inter-version reliability between the original PRWE and the decision …
Evaluation Of The Content Validity Index Of The Australian/Canadian Osteoarthritis Hand Index, The Patient-Rated Wrist/Hand Evaluation And The Thumb Disability Exam In People With Hand Arthritis, Pavlos Bobos, Joy C. Macdermid, Eleni C. Boutsikari, Emily A. Lalone, Louis Ferreira, Ruby Grewal
Evaluation Of The Content Validity Index Of The Australian/Canadian Osteoarthritis Hand Index, The Patient-Rated Wrist/Hand Evaluation And The Thumb Disability Exam In People With Hand Arthritis, Pavlos Bobos, Joy C. Macdermid, Eleni C. Boutsikari, Emily A. Lalone, Louis Ferreira, Ruby Grewal
Bone and Joint Institute
© 2020 The Author(s). Background: The Australian/Canadian Osteoarthritis Hand Index (AUSCAN), the Patient-Rated Wrist/Hand Evaluation (PRWHE) and the Thumb Disability Exam (TDX) are patient-reported outcome measures (PROM) designed to assess pain and hand function in patients with hand arthritis, hand pain and disability, or thumb pathology respectively. This study evaluated the content validity of AUSCAN, PRWHE and TDX in people with hand arthritis. Methods: This study enrolled participants with hand arthritis to rate the items of all 3 PROM in terms of relevance and clarity. The Content Validity Index (CVI) was computed for each item in each scale (I-CVI) as …
Application Of A Novel Automatic Method For Determining The Bilateral Symmetry Midline Of The Facial Skeleton Based On Invariant Moments, Rodrigo Dalvit Carvalho Da Silva, Thomas Richard Jenkyn, Victor Alexander Carranza
Application Of A Novel Automatic Method For Determining The Bilateral Symmetry Midline Of The Facial Skeleton Based On Invariant Moments, Rodrigo Dalvit Carvalho Da Silva, Thomas Richard Jenkyn, Victor Alexander Carranza
Bone and Joint Institute
© 2020 by the authors. Assuming a symmetric pattern plays a fundamental role in the diagnosis and surgical treatment of facial asymmetry, for reconstructive craniofacial surgery, knowing the precise location of the facial midline is important since for most reconstructive procedures the intact side of the face serves as a template for the malformed side. However, the location of the midline is still a subjective procedure, despite its importance. This study aimed to automatically locate the bilateral symmetry midline of the facial skeleton based on an invariant moment technique using pseudo-Zernike moments. A total of 367 skull images were evaluated …
The Architectural Evolution Of Self-Immolative Polymers, Quinton E.A. Sirianni, Elizabeth R. Gillies
The Architectural Evolution Of Self-Immolative Polymers, Quinton E.A. Sirianni, Elizabeth R. Gillies
Bone and Joint Institute
© 2020 Elsevier Ltd Self-immolative polymers (SIPs) depolymerize to small molecules through a cascade of reactions following cleavage of the polymer backbone or a specific terminal or focal point moiety by a stimulus. They have been developed using the principles of self-immolative spacers and low ceiling temperature (Tc) polymers. Key developments over the past couple of decades have been the polymerization of spacers to enable long reaction cascades, and the introduction of stimuli-responsive end-caps which have allowed depolymerization to be triggered in a controlled manner in response to a wide array of stimuli. This review will focus on the architectural …
Neutral, Water-Soluble Poly(Ester Amide) Hydrogels For Cell Encapsulation, Natalie Liang, Lauren E. Flynn, Elizabeth R. Gillies
Neutral, Water-Soluble Poly(Ester Amide) Hydrogels For Cell Encapsulation, Natalie Liang, Lauren E. Flynn, Elizabeth R. Gillies
Bone and Joint Institute
© 2020 Elsevier Ltd Hydrogels are of significant interest for cell encapsulation and delivery in regenerative medicine. Poly(ester amide)s (PEAs) are a class of biodegradable polymers that exhibit promise for biomedical applications due to the degradability of the ester and amide linkages in their backbones, their preparation from biomolecules such as amino acids, and the ability to readily tune their properties through a modular synthesis approach. Water-soluble PEAs containing cationic arginine moieties have previously been developed, but to the best of our knowledge, neutral water-soluble PEAs based on non-charged amino acids have not been reported. Using a poly(ethylene glycol) (PEG)-based …
A Large-Scale Fifteen-Year Minimum Survivorship Of A Cementless Triple Tapered Femoral Stem, Evangelos Tyrpenou, Amir Khoshbin, Shoaib Mohammad, Emil H. Schemitsch, James P. Waddell, Amit Atrey
A Large-Scale Fifteen-Year Minimum Survivorship Of A Cementless Triple Tapered Femoral Stem, Evangelos Tyrpenou, Amir Khoshbin, Shoaib Mohammad, Emil H. Schemitsch, James P. Waddell, Amit Atrey
Bone and Joint Institute
© 2020 Elsevier Inc. Background: This study reports the long-term outcomes of a metaphyseal fit-and-fill cementless femoral component in total hip arthroplasty (THA) with a follow-up of 15-19 years. Methods: We conducted a retrospective review of 376 consecutive THAs (345 patients), using a triple tapered stem performed between 2000 and 2003 with a view to assessing survivorship and radiological and functional outcomes. Images were assessed for initial alignment, terminal osteolysis, or subsidence, while clinical outcomes were assessed using the St Michael's Hip Score. Results: Forty-five (11.9%) hips were lost to follow-up, 20 (5.31%) had died before our 15-year cutoff follow-up, …
Clinical Outcomes After Anterior Cruciate Ligament Injury: Panther Symposium Acl Injury Clinical Outcomes Consensus Group, Eleonor Svantesson, Eric Hamrin Senorski, Kate E. Webster, Jón Karlsson, Theresa Diermeier, Benjamin B. Rothrauff, Sean J. Meredith, Thomas Rauer, James J. Irrgang, Kurt P. Spindler, C. Benjamin Ma, Volker Musahl, Freddie H. Fu, Olufemi R. Ayeni, Francesco Della Villa, Stefano Della Villa, Scott Dye, Mario Ferretti, Alan Getgood, Timo Järvelä, Christopher C. Kaeding, Ryosuke Kuroda, Bryson Lesniak, Robert G. Marx, Gregory B. Maletis, Leo Pinczewski, Anil Ranawat, Bruce Reider, Romain Seil, Carola Van Eck, Brian R. Wolf, Patrick Yung, Stefano Zaffagnini
Clinical Outcomes After Anterior Cruciate Ligament Injury: Panther Symposium Acl Injury Clinical Outcomes Consensus Group, Eleonor Svantesson, Eric Hamrin Senorski, Kate E. Webster, Jón Karlsson, Theresa Diermeier, Benjamin B. Rothrauff, Sean J. Meredith, Thomas Rauer, James J. Irrgang, Kurt P. Spindler, C. Benjamin Ma, Volker Musahl, Freddie H. Fu, Olufemi R. Ayeni, Francesco Della Villa, Stefano Della Villa, Scott Dye, Mario Ferretti, Alan Getgood, Timo Järvelä, Christopher C. Kaeding, Ryosuke Kuroda, Bryson Lesniak, Robert G. Marx, Gregory B. Maletis, Leo Pinczewski, Anil Ranawat, Bruce Reider, Romain Seil, Carola Van Eck, Brian R. Wolf, Patrick Yung, Stefano Zaffagnini
Bone and Joint Institute
© 2020, The Author(s). Purpose: A stringent outcome assessment is a key aspect for establishing evidence-based clinical guidelines for anterior cruciate ligament (ACL) injury treatment. The aim of this consensus statement was to establish what data should be reported when conducting an ACL outcome study, what specific outcome measurements should be used and at what follow-up time those outcomes should be assessed. Methods: To establish a standardized approach to assessment of clinical outcome after ACL treatment, a consensus meeting including a multidisciplinary group of ACL experts was held at the ACL Consensus Meeting Panther Symposium, Pittsburgh, PA; USA, in June …
Follow-Up Study Evaluating The Long Term Outcome Of Chondromimetic In The Treatment Of Osteochondral Defects In The Knee, Agnes Berta, Matthew S. Shive, Andrew K. Lynn, Alan Getgood, Saara Totterman, Grahame Busby, Jerome Hollenstein, Gábor Vásárhelyi, Imre Kéki, László Hangody
Follow-Up Study Evaluating The Long Term Outcome Of Chondromimetic In The Treatment Of Osteochondral Defects In The Knee, Agnes Berta, Matthew S. Shive, Andrew K. Lynn, Alan Getgood, Saara Totterman, Grahame Busby, Jerome Hollenstein, Gábor Vásárhelyi, Imre Kéki, László Hangody
Bone and Joint Institute
© 2020 by the authors. Scaffolds are thought to be a key element needed for successful cartilage repair treatments, and this prospective extension study aimed to evaluate long-term structural and clinical outcomes following osteochondral defect treatment with a cell-free biphasic scaffold. Structural outcomes were assessed using quantitative 3-D magnetic resonance imaging (MRI) and morphological segmentation to determine the percentage of defect filling and repair cartilage T2 relaxation times, and clinical outcomes were determined with the modified Cincinnati Rating System, and the Knee Injury and Osteoarthritis Outcome Score (KOOS). Seventeen subjects with osteochondral defects in the knee were treated with ChondroMimetic …
Contemporary Strategies To Prevent Infection In Hip And Knee Arthroplasty, Lachlan M. Batty, Brent Lanting
Contemporary Strategies To Prevent Infection In Hip And Knee Arthroplasty, Lachlan M. Batty, Brent Lanting
Bone and Joint Institute
© 2020, Springer Science+Business Media, LLC, part of Springer Nature. Purpose of Review: Prosthetic joint infection (PJI) remains a serious concern in lower limb arthroplasty. Despite the significant consequences of PJI, the assessment of the safety and efficacy of preventative measures is challenging due to a low event rate. Notwithstanding, enormous efforts have been made in this arena, and prevention strategies continue to evolve. This review provides an update on contemporary literature (published within the last 5 years) pertaining to infection prevention in primary hip and knee arthroplasty. Recent Findings: Patient optimization has been highlighted as a critical preoperative factor …
Agreement Between Original And Rasch-Approved Neck Disability Index, Ze Lu, Joy C. Macdermid, Goris Nazari
Agreement Between Original And Rasch-Approved Neck Disability Index, Ze Lu, Joy C. Macdermid, Goris Nazari
Bone and Joint Institute
© 2020 The Author(s). Background: Given the high prevalence of neck pain, the neck disability index (NDI) has been used to evaluate patient status and treatment outcomes. Modified versions were proposed as solutions to measurement deficits in the NDI. However, the original 10-item NDI was scored out of 50 and is still the most frequently administered version. Examining the extent of agreement between traditional and Rasch-based versions using Bland-Altman (B&A) plots will inform our understanding of score differences that might rise from using different versions. Therefore, the objective of current study was to describe the extent of agreement between different …
Appraisal Of Clinical Practice Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain, Stephanie Reischl, Joy C. Macdermid
Appraisal Of Clinical Practice Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain, Stephanie Reischl, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Clinical Outcomes After Anterior Cruciate Ligament Injury: Panther Symposium Acl Injury Clinical Outcomes Consensus Group, Eleonor Svantesson, Eric Hamrin Senorski, Kate E. Webster, Jón Karlsson, Theresa Diermeier, Benjamin B. Rothrauff, Sean J. Meredith, Thomas Rauer, James J. Irrgang, Kurt P. Spindler, C. Benjamin Ma, Volker Musahl, The Panther Symposium Acl Injury Clinical Outcomes Consensus Group, Freddie H. Fu, Olufemi R. Ayeni, Francesco Della Villa, Stefano Della Villa, Scott Dye, Mario Ferretti, Alan Getgood, Timo Järvelä, Christopher C. Kaeding, Ryosuke Kuroda, Bryson Lesniak, Robert G. Marx, Gregory B. Maletis, Leo Pinczewski, Anil Ranawat, Bruce Reider, Romain Seil, Carola Van Eck, Brian R. Wolf, Patrick Yung
Clinical Outcomes After Anterior Cruciate Ligament Injury: Panther Symposium Acl Injury Clinical Outcomes Consensus Group, Eleonor Svantesson, Eric Hamrin Senorski, Kate E. Webster, Jón Karlsson, Theresa Diermeier, Benjamin B. Rothrauff, Sean J. Meredith, Thomas Rauer, James J. Irrgang, Kurt P. Spindler, C. Benjamin Ma, Volker Musahl, The Panther Symposium Acl Injury Clinical Outcomes Consensus Group, Freddie H. Fu, Olufemi R. Ayeni, Francesco Della Villa, Stefano Della Villa, Scott Dye, Mario Ferretti, Alan Getgood, Timo Järvelä, Christopher C. Kaeding, Ryosuke Kuroda, Bryson Lesniak, Robert G. Marx, Gregory B. Maletis, Leo Pinczewski, Anil Ranawat, Bruce Reider, Romain Seil, Carola Van Eck, Brian R. Wolf, Patrick Yung
Bone and Joint Institute
© The Author(s) 2020. A stringent outcome assessment is a key aspect of establishing evidence-based clinical guidelines for anterior cruciate ligament (ACL) injury treatment. To establish a standardized assessment of clinical outcome after ACL treatment, a consensus meeting including a multidisciplinary group of ACL experts was held at the ACL Consensus Meeting Panther Symposium, Pittsburgh, Pennsylvania, USA, in June 2019. The aim was to establish a consensus on what data should be reported when conducting an ACL outcome study, what specific outcome measurements should be used, and at what follow-up time those outcomes should be assessed. The group reached consensus …
Appraisal Of Clinical Practice Guideline: Optima Revised Recommendations For Non-Pharmacological Management Of Persistent Headaches Associated With Neck Pain, Stephanie Reischl, Armaghan Dabbagh, Joy C. Macdermid
Appraisal Of Clinical Practice Guideline: Optima Revised Recommendations For Non-Pharmacological Management Of Persistent Headaches Associated With Neck Pain, Stephanie Reischl, Armaghan Dabbagh, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Does Endoscopic Sinus Surgery Alter The Biomechanics Of The Orbit?, Leigh J. Sowerby, Matthew S. Harris, Rootu Joshi, Marjorie Johnson, Tom Jenkyn, Corey C. Moore
Does Endoscopic Sinus Surgery Alter The Biomechanics Of The Orbit?, Leigh J. Sowerby, Matthew S. Harris, Rootu Joshi, Marjorie Johnson, Tom Jenkyn, Corey C. Moore
Bone and Joint Institute
© 2020 The Author(s). Objective: The purpose of this study is to determine if removal of ethmoid cell septations as commonly performed in endoscopic sinus surgery leads to a change in orbital wall fracture patterns and the force required to create them. Methods: Six fresh-frozen cadaveric heads were acquired and underwent endoscopic uncinectomy, maxillary antrostomy, and anterior and posterior ethmoidectomy on one, randomized, side. The contralateral sinuses were used as intra-specimen control. Hyaluronic acid gel globe injections were performed to simulate normal intra-ocular pressure. Post-op CT scans confirmed no orbital fractures or violation of the lamina papyracea prior to trauma …