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Intracranial Mri Findings In A Patient With Fbxo11- Related Disorder, Vishal Chandra, Anjali Aggarwal, Amanda Moen, Sasha Strul, Can Özütemi̇z

Journal of Pediatric Neurology

FBXO11-related intellectual developmental disorder with dysmorphic facies and behavioral abnormalities is a rare genetic disorder. Brain magnetic resonance imaging (MRI) findings associated with this disorder have been sparsely described in literature. This case report describes and depicts brain MRI of a patient with FBXO11-related disorder. The radiologic findings within this report aim to improve the knowledge of the radiologists and clinicians in the detection of this rare condition.

Anterior Cutaneous Neurectomy - Child's Play?, Srivatsan Thirumalai Vasu, Sudish Karunakaran, Gangadharan V. P., Arun Oommen, Ajay Kumar Ajanvi, Anil Chiluka, Govind Gangadharan, Renu Paul

Journal of Pediatric Neurology

Chronic abdominal pain (CAP) is a common entity in the pediatric population and has an extensive differential diagnosis. Anterior cutaneous nerve entrapment syndrome (ACNES) is an etiology that is not often diagnosed and requires an individualized approach. Treatment options for ACNES include nonsurgical and surgical, often a graded approach is used. A 12-year-old boy presented with CAP and was extensively evaluated as well as underwent multiple abdominal surgeries. He was eventually diagnosed with ACNES and underwent a trial conservative management. Although he initially showed improvement, his pain returned. He later underwent a neurectomy procedure with significant postoperative relief. The patient …

Toe Walking In A Formerly Preterm Child: Is It Just Cerebral Palsy?, Nankee K. Kumar, Ashley M. Bach, Deborah M. Zarnow, Kavita Desai, Benjamin C. Kennedy, Sonika Agarwal

Journal of Pediatric Neurology

Spastic diplegic cerebral palsy (CP) is common among children born preterm and is a known cause of toe walking. By contrast, pediatric tumors of the conus medullaris are rare. We report the case of a 28-month-old formerly extremely preterm male with global developmental delay who presented with toe walking, constipation, and asymmetric hypertonia of the lower extremities. Brain imaging revealed periventricular leukomalacia, ex-vacuo ventricular dilation, and cerebellar dysplasia consistent with a diagnosis of CP secondary to perinatal injury. Lumbar spine imaging obtained due to his worsening constipation and pain while walking demonstrated an intramedullary, well-circumscribed, contrast-enhancing lesion in the conus …

The Effectiveness Of Botulinum Toxin Injections To The Extremities In The Pediatric Population With Severe Cerebral Palsy: A Systematic Review, Debra A. Sala, Eduardo Del Rosario

Journal of Pediatric Neurology

The purpose of this review was to examine the effectiveness of botulinum toxin injections to the upper and lower extremities reported in studies of pediatric participants with severe cerebral palsy on improving ease of care, pain and motor function. PubMed, CINAHL, and Web of Science were searched using combinations of cerebral palsy and various types and abbreviations of botulinum toxin. Additionally, reference lists and citations of reviewed studies were searched. The results of 25 studies were reviewed: three randomized controlled trials (RCT), and 22 non-randomized studies of interventions involving only a botulinum toxin-treated group. Seven studies focused solely on the …

Textvantage, Palakh Shangle

Defensive Publications Series

The present disclosure discloses TextVantage is AI-powered accessibility framework designed to enhance digital finance platform for dyslexic users and merchants. The Present disclosure includes UI Enhancements include Dyslexic-friendly fonts (e.g., OpenDyslexic), text simplification, increased line spacing, and text-to-speech narration. Further, hybrid inputs include Text queries, voice commands (via Web Speech API), autodetection of complex text, and visual toggles for font/spacing/narration. Further, RAG Pipeline retrieves dyslexia research, WCAG guidelines, and text simplification strategies to power an LLM that generates tailored responses (e.g., simplified text, merchant code). The present disclosure discloses merchant support includes Auto-generates dyslexic-friendly code or content via file …

The Healthcare Workforce In Nevada, 2024, Olivia K. Cheche, William E. Brown Jr., Caitlin J. Saladino

Health

This fact sheet presents data on the healthcare workforce in Nevada. The U.S. Bureau of Labor Statistics’ Occupational Employment and Wage Statistics Query System provides data on the amount of employment in all job sectors at the state and metropolitan statistical area (MSA) levels. This fact sheet focuses on employment and wage data for the State of Nevada, the Las Vegas-Henderson-Paradise, NV MSA, and the Reno, NV MSA as of May 2024.

District Impact On State-Wide Charter School Policy: Has Normandy Schools Collaborative Punctuated The Equilibrium? Charter School Policy Analysis Of The Missouri Department Of Elementary And Secondary Education, Tracey L. Cannon

Dissertations

Abstract

Punctuated Equilibrium Theory, as applied by Niles Eldredge and Stephen Jay Gould (1941-2002) to the study of species evolution, examined the infrequency of morphological change or stasis discontinuity.1 While groundbreaking in the field of Paleontology and the study of fossil change, the theory has been well-fitting to the decision sciences as introduced by Baumgartner and Jones2, in their 1993 and 2010 publications. Recognizing typical, incremental policy change, its use in this research looks at how stasis, stagnant policy can be punctuated by changes in political or societal views. This study examines the impact of heightened problem discussion for agenda …

A Narrative Study Of How Secondary School Teachers Experience Generative Ai Writing Tools In The English Language Arts Classroom, Nick Brodell

Doctor of Education (EdD)

With the presence of artificial intelligence (AI) programs such as ChatGPT commonplace in secondary English language arts (ELA) classrooms, scholars and practitioners are both curious and skeptical about the technology’s ability to help students improve their ELA skills. Teachers have been using tutoring software and Web 2.0 technologies for decades, yet AI writing tools offer new functionalities. Teachers and administrators have experiences engaging with the benefits and burdens of the technology, and scholars of composition pedagogy, ITS (intelligent tutoring systems), and ML (machine learning) have theories about students using it for skills acquisition and practice. This study collected and analyzed …

Signal And Noise Analysis In An Undergraduate Instrumental Analysis Laboratory, Ken Overway

Chemistry Faculty Scholarship

Understanding the difference between signal and noise in a measurement is fundamental to analytical chemists. The typical instruments found in an undergraduate chemistry department can be used to teach this concept, as well as signal averaging, by giving students hands-on experience with measurements and data processing. This work presents an undergraduate laboratory module (homework and experiment) that provides specific instructions for using gas chromatographs, fluorometers, a nuclear magnetic resonance spectrometer, an atomic absorption spectrophotometer, and an infrared spectrometer to collect replicate measurements and a framework for calculating the noise level, baseline, signal level, signal-to-noise ratio (SNR), and the signal thresholds …

Atom-Chip Compatible Optical Lattice, Robert Leonard, Spencer E. Olson

Space Dynamics Laboratory Publications

A lattice beam configuration which results in an isotropic 3D trap near the surface of an atom chip is described. The lattice is formed near the surface of a reflectively coated atom chip, where three incident beams and three reflected beams intersect. The coherent interference of these six beams form a phase-stable optical lattice which extends to the surface of the atom chip. The lattice is experimentally realized and the trap frequency is measured. Degenerate Raman sideband cooling is performed in the optical lattice, cooling 80 million atoms to 1.1 μK.

Incidence And Clinical Profile Of Cardiovascular Abnormalities In Infants Of Diabetic Mother, Kailas Randad, Praveen Das, Akash Dnyandeo Sarkate, Qudsiya Ansari

Digital Journal of Clinical Medicine

Background: Maternal diabetes is associated with adverse pregnancy outcomes, notably congenital heart disease (CHD) in infants of diabetic mothers (IDMs). This study evaluated the prevalence and spectrum of CHDs in IDMs and the effect of maternal glycemic control.

Materials and Methods: A prospective observational study was conducted over 18 months at a tertiary care centre in Mumbai. A total of 112 IDMs were enrolled. Maternal glycemic status was assessed using HbA1c and random blood sugar. All infants underwent clinical examination, oxygen saturation measurement, and echocardiography.

Results: CHDs were identified in 26.7% of infants. The most frequent lesions …

Ti-Ulpcs: Threshold-Issuance - Un-Linkable Policy Compliant Signatures, Kiran Deep Ghosh

Master’s Dissertations

Digital signatures, as a strong cryptographic primitive, ensure the authenticity and integrity of signed messages. On one hand, no one can forge a verifiable signature without knowing the secret key, on the other hand, any correctly formed signature is always verifiable under the public key of the signer. Besides signing digital data, they serve as foundational components in more advanced cryptographic systems, including blind signatures, group signatures, direct anonymous attestation, e-cash, e-voting protocols, adaptive oblivious transfer, anonymous credential schemes, Policy-Compliant Signatures, etc. Policy-Compliant Signatures (PCS) enable the enforcement of joint policies between the signer and the verifier. A signature of …

The Kentucky Microbiome Dataset, Rachel L. Washburn, Douglas C. Curl

Research Data--KGS

The Kentucky Microbiome Dataset is a continuously updated geolocated dataset which describes the distribution and diversity of microorganisms across the Commonwealth of Kentucky. Each geolocated point represents a location reported in the peer-reviewed literature where microorganisms were sampled from soil, water, geologic substrates, or clinical settings. Environmental studies include only non-host-associated, non-clinical microorganisms sampled from natural environments. Clinical studies are mapped separately to highlight locations where investigations into host-associated or human health-related microbes have occurred.

For each location, associated metadata include study information, taxonomic classifications, sample type, sampling method, latitude and longitude, sampling date, publication reference, and a direct link …

Welch Foods Inc. V. General Teamsters Local Union No. 397

2025 Decisions

USDC for the Western District of Pennsylvania

Native American Elders’ Perspectives On Death And Dying, Ji Hong, Stephenie M. Wescoup, Gul Nahar, Rockey Robbins

Journal of Indigenous Research

This article employs a qualitative method to facilitate the expression of 16 Native American elders about their feelings about aging and death. They discussed resentments, acceptance of their life experiences, the inevitability of death, participation in the natural re-cycling of nature, and hopes they had for Native Americans in future generations. Throughout the study, theoretical and empirical findings in the field of psychology and Native American literature are cited to help interpret the participants’ remarks. An extended clinical implications section may be helpful to practitioners.

Precision Spectral Measurements Of Chromium And Titanium From 10 To 250  Gev/N And Sub-Iron To Iron Ratio With The Calorimetric Electron Telescope On The International Space Station, O. Adriani, Y. Akaike, K. Asano, Y. Asaoka, E. Berti, P. Betti, G. Bigongiari, W. R. Binns, M. Bongi, P. Brogi, A. Bruno, N. Cannady, G. Castellini, C. Checchia, M. L. Cherry, G. Collazuol, G. A. De Nolfo, K. Ebisawa, A. W. Ficklin, H. Fuke, S. Gonzi, T. G. Guzik, T. Hams, K. Hibino, M. Ichimura, M. H. Israel, K. Kasahara, J. Kataoka, R. Kataoka, Y. Katayose, C. Kato, N. Kawanaka, Y. Kawakubo

Faculty Publications

The Calorimetric Electron Telescope (CALET), in operation on the International Space Station since 2015, collected a large sample of cosmic-ray (CR) iron and sub-iron events over a wide energy interval. In this Letter, we report an update of our previous measurement of the iron flux and we present-for the first time-a high statistics measurement of the spectra of two sub-iron elements Cr and Ti in the energy interval from 10 to 250  GeV/n. The analyses are based on 8 years of data. Differently from older generations of cosmic-ray instruments which, in most cases, could not resolve individual sub-iron elements, CALET …

Ideal Mathematical Pendulum: Examples Of Physics Problem Conditions Expressed Primarily Through Diagrams, Vasiliy Znamenskiy

Open Educational Resources

This article explores an innovative approach to physics education centered on the formulation of problems using visual diagrams with minimal textual description. Departing from traditional word-heavy methods, the proposed technique leverages schematic drawings as the primary mode of problem presentation. This visual-first strategy facilitates intuitive understanding, promotes spatial reasoning, and supports the development of abstract thinking in students. The method is especially effective in diverse classrooms where language barriers may hinder comprehension. By engaging learners through image-based tasks, the approach reduces cognitive load, fosters independent discovery of physical principles, and enhances overall conceptual clarity. Examples from mechanics and oscillations illustrate …

Re: Comment Letter For 2024 Annual Operations And Maintenance Report Butte Reclamation Evaluation System (Bres) Annual Summary Report For Work Completed In Quadrant 4 (Dated May 1, 2025), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Preparation And Properties Of Rutin-Casein Complexes, Zhang Nan, Liu Lili, Yang Le, Li Sisi, Zhang Xinyuan

Food and Machinery

［Objective］ To investigate the effect of complexes produced by protein -polyphenol interaction on the bioavailability of polyphenols and proteins.［Methods］ Rutin -casein complexes are prepared using rutin and casein as raw materials.Their physicochemical and structural properties are analyzed.［Results］］ The optimal preparation conditions for the rutin -casein complexes are determined as follows:mass ratio of rutin to casein =1.89∶1.00,reaction time of 5.94 h,pH 8.5,and temperature of 50 ℃.Under such conditions,the binding degree is 40.23%.Compared with casein,the complexes exhibit a decrease in emulsifying activity index (8.47 m2/g) and emulsifying stability (9.39%).The solubility increases by 5.11%,surface hydrophobicity is significantly enhanced,and antioxidant activity markedly improves (P<0.05).Scanning electron microscopy reveals that the rutin -casein complexes display a lamellar structure with smooth surfaces,which may contribute to its functional properties.Infrared spectroscopy demonstrates peak broadening and redshifts in the amide I and II bands,and fluorescence intensity (including synchronous fluorescence ) decreases due to fluorescence quenching.It indicates that rutin alters the secondary structure and conformational arrangement of casein.［Conclusion］ Compared with the uncomplexed casein,the rutin -casein complexes are enhanced in solubility,surface hydrophobicity,and antioxidant activity.引用格式：张楠，刘丽莉，杨乐，等.芦丁—酪蛋白复合物的制备及特性研究 ［J］.食品与机械，2025，41（7）：9-17.C itation:ZHANG Nan,LIU Lili,YANG Le,et al.Preparation and properties of rutin-casein complexes [J].Food & Machinery,2025,41(7):9-17.

Ultrasound-Assisted Enzymatic Extraction And Structural Characterization Of Pectin From The Tender Leaves Of Abelia Macrotera, Mao Qiqi, Luo Yang, Wang Jianglin, Luo Jie, Fan Xiankang, Liu Chengguo, Zhou Hui

Food and Machinery

［Objective］ To clarify the physicochemical properties,microscopic structure,monosaccharide composition,relative molecular mass,and structural characteristics of pectin in the tender leaves of Abelia macrotera.［Methods］ Pectin from the tender leaves of Abelia macrotera was extracted by ultrasound -assisted cellulase method.The microscopic structure was observed under scanning electron microscope.The monosaccharide composition was determined by high performance liquid chromatography.The relative molecular mass was determined by polysaccharide hydrolysis derivatization.The possible structure was inferred by infrared spectroscopy.［Results］］ The yield of pectin from the tender leaves of Abelia macrotera is 23.38%,the esterification degree was 1.17%,and the galacturonic acid content was 72.16%.The pectin is in the form of flakes with …

Effects Of Sodium Chloride Treatment On The Functional Characteristics And Structure Of Porcine Plasma Protein, Wang Deqiang, Zhao Longyuan, Tang Huaijian, Ma Yihao, Jia Feng

Food and Machinery

［Objective］ To explore the effects of sodium chloride (NaCl ) on the functional and structural properties of porcine plasma proteins (PPP),with the aim of providing a reference for the practical application of PPP.［Methods］ PPP was treated with different concentrations of NaCl (0~1.0 mol/L ),and changes in its functional and structural properties were measured using ultraviolet -visible spectrophotometry,laser particle size analysis,and Zeta potential analysis.［Results］］ NaCl promoted the solubility of PPP,reaching a peak at 0.2 mol/L.With further increases in NaCl concentration,solubility showed a downward trend.The trends in surface hydrophobicity and emulsifying properties of PPP changed at 0.8 mol/L,with maximum increases of 69.75% …

Effects Of Electron Beam Irradiation On Carotenoids And Capsaicinoids In Pepper Oils Prepared By Different Plant Oils, Ouyang Mengyun, Li Wenge, Cao Sheng, Mo Mo, Zhou Yiji, Zhang Qiling, Xu Yuanfang

Food and Machinery

［Objective］ To investigate the irradiation stability of carotenoids and capsaicinoids in pepper oils prepared using different plant oils.［Methods］ With rapeseed oil (RO),soybean oil (SO),and their blended oil (RSO ) as materials,pepper oils RO -P,SO-P,and RSO -P were prepared,and subjected to high -energy electron beam irradiation (10 MeV ).The effects of different irradiation doses (4~12 kGy ) on the peroxide value (PV),acid value (AV),carotenoid content,and capsaicinoid content of the pepper oils were investigated.［Results］］ Electron beam irradiation promoted lipid oxidation in the pepper oils,resulting in increased PV and AV values,with SO -P exhibiting the highest degree of lipid oxidation.When the irradiation dose …

Optimization Of Sulfur-Free Color Protection Process And Comparison Of Drying Techniques For Honeysuckle, Zhai Yumei, Tang Xiaojuan, Fu Xiao, Gong Min, Liu Yunguo

Food and Machinery

［Objective］ To develop green processing technology to inhibit the browning of fresh honeysuckle (Lonicera japonica Thunb ) and enhance its drying quality.［Methods］ With polyphenol oxidase relative enzyme activity and color difference values as evaluation indicators,the process of sulfur -free compound color -protecting agents (citric acid,D-sodium erythorbate,and DL-sodium malate ) is optimized through response surface methodology.Additionally,the effect of various drying methods,including vacuum freeze drying and microwave drying,on the quality after color protection is compared and analyzed.［Results］］ Citric acid demonstrates the best anti -browning effect.The process parameters are optimal when citric acid concentration is 0.105 mol/L,with D-sodium erythorbate concentration of 0.124 mol/L …

Protective Effects Of Lactobacillus Rhamnosus Cqfp 202412 On The Brain , Intestines , And Motor Functions Of Antibiotic-Damaged Mice, Cheng Bo, Li Chong, Meng Xianlu

Food and Machinery

［Objective］ To explore the effects of Lactobacillus rhamnosus CQFP 202412 on improving the intestinal barrier,liver,brain neurons,and motor function in mice through its antioxidant and anti -inflammatory activities.［Methods］ A mouse model was established by intraperitoneal injection of a mixed antibiotic solution (neomycin 5 mg/mL,vancomycin 25 mg/mL,amphotericin B 0.1 mg/mL,ampicillin 10 mg/mL,metronidazole 5 mg/mL,and lipopolysaccharide 1.5 μg/mL ),followed by intervention with L.rhamnosus CQFP 202412.After the intervention,weight -loaded swimming time and running exhaustion time were measured,along with liver index and oxidative stress/inflammatory markers in serum and brain tissue.Histopathological changes in the brain were observed by HE staining,and PCR was used to detect the …

Anti-Fatigue Activity Of Lycium Barbarum Polysaccharides, Sun Xin, Fan Shijun

Food and Machinery

［Objective］ To clarify the main components of Lycium barbarum polysaccharides that exert an anti -fatigue effect.［Methods］ Lycium barbarum polysaccharides with different relative molecular weights are prepared by water extraction,ultrafiltration membrane fractionation dialysis,and other methods.The components with good anti -fatigue activity are obtained by mice burden swimming test.They are then eluted and purified by ion exchange column and gel chromatography column to determine the relative molecular weights and monosaccharide components.The infrared spectrum is employed to analyze.［Results］］ The content of polysaccharide,protein,and uronic acid in Lycium barbarum polysaccharides with different molecular weights is 63.62%~75.63%,1.77%~2.63%,and 17.77%~24.77%,respectively.The LBP 2 has a higher component yield.The relative …

Effect Of Polygonatum Sibiricum Powder On Properties Of Dough And Quality Of Bread, Wu Kunwei, Wei Ming, Qian Senhe, Li Ziman, Xie Yan

Food and Machinery

［Objective］ To explore the application of Polygonatum sibiricum powder in bread,enhancing its health benefits.［Methods］ Polygonatum powder is added to wheat flour to study its effects on starch gelatinization,gluten structure,dough rheological properties,and bread baking quality.［Results］］ The addition of Polygonatum powder increases the gelatinization temperature of the flour,while peak viscosity and retrogradation values decrease.The gluten yield in the dough is reduced.Changes in the secondary structure of gluten proteins are observed,with an increase in the content of random coil structures.Polygonatum sibiricum powder increases dough hardness,elasticity modulus,and viscosity modulus,but it reduces the dough's fermentation volume.The baking quality of the bread is affected,with the bread …

Research Progress In The Effects Of Processing Techniques On Catechins In Green Tea, Yuan Fangzheng, Wei Yu, Li Fengling, Du Xuehui, Shi Haichuan, Gao Aiying

Food and Machinery

Catechins are the key substances that endow green tea with a bitter and astringent taste,and the changes in their structures and content have an important effect on the flavor quality of green tea.By collating the current research results related to catechins,this paper summarizes the changes of catechins during the main processing steps including withering,de-enzyming,rolling,and drying of green tea,and explores the main mechanisms of changes in catechins during processing and their effects on the bitterness and astringency of green tea.

Advances In The Application Of Machine Learning To Food Nutrition And Health, Zhou Xin, Li Dapeng

Food and Machinery

A balanced diet is fundamental to maintaining human health and preventing or reducing the risk of chronic non -communicable diseases.Efficient and accurate analysis of nutritional and functional components in food,followed by the provision of personalized nutritional guidance,is a research hotspot in the field of food nutrition and health.This article reviews the research progress on artificial intelligence technologies,such as machine learning,in the analysis of food nutritional components,functional component analysis and screening,and personalized nutrition,and highlights the pressing issues that need to be addressed in this field.

Effects Of Drying Conditions On The Forming Process , Structure , And Properties Of Konjac Glucomannan-Based Emulsion Films, Liu Yi, Zhu Jingyu, Cheng Yuhang, Yu Xiang, Jiang Fatang

Food and Machinery

［Objective］ To investigate the mechanism by which lipid distribution induced by drying conditions affects the structure and physicochemical properties of konjac glucomannan -based emulsion films.［Methods］ A film -forming emulsion composed of konjac glucomannan,pectin,and basil essential oil (K-P-OG) was prepared.The effects of different drying temperatures (25 ℃,30 ℃,35 ℃,and 40 ℃) on the physicochemical properties of K -P-OG films were examined.The droplet morphology and water distribution during the film -forming process were tracked using confocal laser scanning microscopy (CLSM ),scanning electron microscopy (SEM ),and low -field nuclear magnetic resonance (LF-NMR ).A rheometer was used to analyze the interactions among components within …

Detecting Misuse Of Security Apis: A Systematic Review, Zahra Mousavi, Chadni Islam, Muhammad Ali Babar, Alsharif Abuadbba, Kristen Moore

Research outputs 2022 to 2026

Security Application Programming Interfaces (APIs) are crucial for ensuring software security. However, their misuse introduces vulnerabilities, potentially leading to severe data breaches and substantial financial loss. Complex API design, inadequate documentation, and insufficient security training often lead to unintentional misuse by developers. The software security community has devised and evaluated several approaches to detecting security API misuse to help developers and organizations. This study rigorously reviews the literature on detecting misuse of security APIs to gain a comprehensive understanding of this critical domain. Our goal is to identify and analyze security API misuses, the detection approaches developed, and the evaluation …